Dentamet- an effective antimicrobial complex that affects the main pathogenic microflora of the oral cavity, which is the main cause of the development of the inflammatory process
Thanks to the adhesive properties of its gel base, Dentamet is reliably fixed in the lesion, which provides a long-term therapeutic effect.
The effectiveness of the drug is due to the presence of two antibacterial components in its composition:
Metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal diseases: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.
Chlorhexidine is a broad-spectrum antiseptic that has a bactericidal effect against vegetative forms of gram-negative and gram-positive microorganisms, as well as yeast, dermatophytes and lipophilic viruses.
Indications for use:
Dentamet intended for the treatment of infectious and inflammatory diseases of periodontal and oral mucosa:
- acute and chronic gingivitis;
- acute ulcerative-necrotizing gingivitis of Vincent;
- acute and chronic periodontitis;
- juvenile periodontitis;
- periodontal disease complicated by gingivitis;
- aphthous stomatitis;
- cheilitis;
- inflammation of the oral mucosa when wearing dentures;
- post-extraction alveolitis (inflammation of the socket after tooth extraction);
- periodontitis, periodontal abscess (as part of combination therapy).
Mode of application:
Dentamet applied topically, for dental use only.
For adults and children over 6 years of age with gum inflammation (gingivitis), Dentamet is applied to the gum area 2 times a day; it is not recommended to wash off the gel. The duration of treatment is on average 7-10 days. After applying the gel, you should refrain from drinking and eating for 30 minutes.
In case of periodontitis, after removing dental plaque, periodontal pockets are treated with Dentamet gel and the gel is applied to the gum area. Exposure time - 30 minutes. The number of procedures depends on the severity of the disease.
In the future, the patient can apply the gel independently: Dentamet is applied to the gum area 2 times a day for 7-10 days.
For aphthous stomatitis, Dentamet is applied to the affected area of the oral mucosa 2 times a day for 7-10 days.
To prevent exacerbations of chronic gingivitis and periodontitis, Dentamet gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses of treatment are carried out 2-3 times a year.
To prevent post-extraction alveolitis after tooth extraction, the hole is treated with Dentamet gel, then the gel is applied on an outpatient basis 2-3 times a day for 7-10 days.
Side effects:
When applying the gel topically Dentamet the risk of developing systemic side effects is low, but sometimes headache and allergic reactions (skin rash, itching, urticaria) may occur.
Contraindications:
Contraindications to the use of the gel Dentamet are: individual intolerance to metronidazole and other derivatives of nitroimidazole, chlorhexidine; intolerance to any components included in the drug; children under 6 years of age.
Interaction with other drugs:
When applied topically in recommended doses, systemic interaction of the gel Dentamet with other drugs not detected.
Overdose:
Cases of drug overdose Dentamet was not observed with topical application.
Storage conditions:
In a dry place, protected from light, at a temperature not exceeding 25 °C.
Keep out of the reach of children.
Release form:
Dentamet - dental gel.
In an aluminum tube 10 or 25 g.
Compound:
100 g of the drug Dentamet contains active ingredients: metronidazole 1g, chlorhexidine gluconate 20% solution 0.5g.
Excipients (adhesive gel base): menthol 0.25 g, glycerin (glycerol) 5 g, propylene glycol 5 g, thermostable triethanolamine 0.47 g, arepol 1.25 g, soluble saccharin 0.25 g, purified water 86.28 g.
Composition and release form of the drug
10 g - tubes (1) - cardboard packs.
25 g - tubes (1) - cardboard packs.
pharmachologic effect
Combined drug for local use.
Metronidazole- a nitroimidazole derivative with antiprotozoal and antibacterial effects against anaerobic protozoa and anaerobic bacteria causing: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenic us, Selenomonas spp.
Inactive against aerobic bacteria.
The mechanism of action is the biochemical reduction of the 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.
- disinfectant, active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It affects bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of dissociation of chlorhexidine salt in a physiological environment) with the negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, it has a bacteriostatic effect; at high concentrations, the cytoplasmic contents of the bacterial cell are precipitated, which ultimately leads to the death of the bacteria.
Indications
Acute gingivitis; Vincent's acute necrotizing ulcerative gingivitis; chronic edematous gingivitis; chronic hyperplastic gingivitis; chronic atrophic (desquamative) gingivitis; chronic periodontitis; periodontal abscess; recurrent aphthous (ulcerative) stomatitis; gangrenous pulpitis; post-extraction alveolitis; juvenile periodontitis; toothache of infectious origin.
Contraindications
Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives); children under 6 years of age.
With caution: pregnancy, lactation period.
Dosage
For dental use only.
Topically, after thoroughly brushing your teeth, apply to the gums and interdental spaces. Apply 2 times/day.
For the purpose of prevention, a small amount is added to toothpaste.
Side effects
Local reactions:"metallic" taste in the mouth.
Systemic reactions:, allergic reactions (skin rash, itching, urticaria).
Drug interactions
Enhances anticoagulant effect warfarin(increased time of prothrombin formation).
Simultaneous use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.
The antimicrobial activity of metronidazole is reduced when used simultaneously with and phenytoin due to accelerated metabolism of metronidazole.
Cimetidine inhibits the metabolism of metronidazole, which may lead to increased concentrations of metronidazole in the blood serum.
special instructions
The use of the drug does not replace hygienic brushing of teeth, therefore, during the course of treatment with the drug, tooth brushing should be continued. However, you should not combine applying the gel with toothpaste.
Avoid contact with eyes.
Pregnancy and lactation
During lactation, if it is necessary to prescribe the drug, the issue of stopping breastfeeding should be decided.
Use in childhood
Contraindication- children under 6 years of age.
Instructions for use
Dentamet instructions for use
Dosage form
Compound
Dental gel 1 g
Metronidazole 10 mg
Chlorhexidine bigluconate (20% solution) 5 mg
Pharmacodynamics
Combined antimicrobial drug. The effectiveness of the drug is due to the presence in its composition of such active ingredients as metronidazole and chlorhexidine.
Metronidazole is a nitroimidazole derivative that has antiprotozoal and antibacterial effects against anaerobic protozoa and anaerobic bacteria that cause periodontitis: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti, Bact eroides melaninogenicus, Selenomonas spp .
Inactive against aerobic bacteria.
The mechanism of action is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microbial cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.
Chlorhexidine is a disinfectant that is active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It affects bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of dissociation of chlorhexidine salt in a physiological environment) with the negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, it has a bacteriostatic effect; at high concentrations, the cytoplasmic contents of the bacterial cell are precipitated, which ultimately leads to the death of the bacteria.
Side effects
“Metallic” taste in the mouth, headache, allergic reactions (skin rash, itching, urticaria).
Selling Features
Available without a prescription
Special conditions
Avoid contact with eyes.
Indications
Acute gingivitis;
Vincent's acute necrotizing ulcerative gingivitis;
Chronic edematous gingivitis;
Chronic hyperplastic gingivitis;
Chronic atrophic (desquamative) gingivitis;
Chronic periodontitis;
Periodontal abscess;
Recurrent aphthous (ulcerative) stomatitis;
Gangrenous pulpitis;
Post-extraction alveolitis;
Juvenile periodontitis;
Toothache of infectious origin.
Contraindications
Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives).
Strengthens the anticoagulant effect of warfarin (increasing the time of prothrombin formation).
Concomitant use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.
The antimicrobial activity of metronidazole is reduced when used simultaneously with phenobarbital and phenytoin due to the accelerated metabolism of metronidazole.
Cimetidine inhibits the metabolism of metronidazole, which may lead to increased metronidazole serum concentrations.
Drug interactions
Avoid contact with eyes.
The use of the drug in pregnant and lactating women is undesirable.
Prices for Dentamet in other cities
Buy Dentamet,Dentamet in St. Petersburg,Dentamet in Novosibirsk,Dentamet in Yekaterinburg,Dentamet in Nizhny Novgorod,Dentamet in Kazan,Dentamet in Chelyabinsk,Dentamet in Omsk,Dentamet in Samara,Dentamet dental gel is one of the most effective antimicrobial agents that affect the main pathogenic microflora in the mouth. This article provides detailed instructions for the use of this medication and its analogues.
General characteristics of the dental product Dentamet
Dentamet belongs to medications with antimicrobial properties, used for the treatment of inflammation of infectious etiology. The drug is produced in the form of a gel of uniform consistency, white in color with a slightly yellow tint.
The drug contains metronidazole– the main active component of the gel is chlorhexidine bigluconate.
Additional components of the medicine consist of:
- Glycerol (distilled glycerin).
- Sodium saccharinate dihydrate.
- Levomenthol (L-Menthol).
- Propylene glycol.
- Carbomer.
- Trolamine (thermostable triethanolamine).
- Purified water.
The gel is available in tubes of ten or twenty-five grams. The tubes are packed in cardboard boxes. Widely used only in dentistry.
Dentamet in gel form belongs to the group of combined antimicrobial drugs. A high treatment effect is achieved thanks to metronidazole and chlorhexidine, which are part of the medicine.
Metronidazole is a nitroimidazole derivative that has an antiprotozoal and antimicrobial effect on anaerobic unicellular organisms and a group of prokaryotes that provoke the development of periodontal inflammation. Has no effect on aerobic prokaryotic microorganisms.
Chlorhexidine is a disinfectant. It is a medicine with a wide range of effects and is highly active. It has a detrimental effect on or suppresses the vital activity of gram-negative and gram-positive microbes, yeast-like fungi, and viruses. Destroys bacterial spores only during hyperthermia.
In what situations is the medication prescribed?
Dentamet dental gel is prescribed in the presence of symptoms:
- Acute gingivitis.
- Vincent's acute necrotizing ulcerative gingivitis.
- Chronic inflammation of the gums.
- Chronic hyperplastic gingivitis.
- Gum atrophy.
- Chronic apical periodontitis.
- Periodontal disease, which was complicated by gingivitis.
- Cavities in periodontal tissues filled with pus.
- Recurrent aphthous (ulcerative) stomatitis.
- Gangrenous pulpitis.
- Post-extraction alveolitis.
- Heilita.
- Prepurbent periodontitis.
- Pain caused by infection.
- Inflammatory process of the gums, provoked by the presence of prosthetic structures in the mouth.
Information! The drug should be prescribed exclusively by a doctor based on diagnostic results.
Instructions for use
You can apply the gel not only with a brush, but also with your finger (be sure to clean your hands).
The drug is used only by dentists for topical application to the affected area of the gum. The rules for the procedure are as follows:
- Carry out good dental hygiene.
- Prepare a solution using baking soda.
- Rinse your mouth with it.
- Dry the mucous membranes of the gums well with a gauze napkin.
- Squeeze the gel, the size of a small pea, onto a toothbrush.
- Using a brush, distribute the gel on the periodontium and the space between the teeth.
- Do not eat or drink water for thirty minutes after applying Dentamet.
- The frequency of use of the gel is twice a day.
- The duration of therapeutic treatment is recommended up to one and a half weeks.
For the purpose of prevention, ointment is used after extraction of a dental unit, aggravation of chronic periodontitis and gingivitis. To do this, squeeze a drop of dentamet into the paste and brush your teeth morning and evening for thirty days in a row. It is necessary to repeat preventive measures every six months.
Use of the gel in pediatrics, pregnancy and lactation
The drug is prescribed to children upon reaching the age of six. Prescribed by dentists for gingivitis and ulcerative stomatitis. For local use only. The gel is applied to the affected area in the morning and evening. They hold it for half an hour, and then they are allowed to rinse their mouth, drink and eat. On average, gel treatment lasts seven to ten days.
During treatment with the gel, you should not cancel hygienic brushing of your teeth. Experts do not recommend using the drug during pregnancy and breastfeeding.
Important! Self-prescription of dentament for children and during gestation of the intrauterine fetus contributes to the formation of irreversible consequences.
Contraindications and side effects
The drug is contraindicated for:
- Individual intolerance to one or more components of dentamet.
- Not recommended for children under six years of age. This is associated with insufficient study of the safe and effective effects of the drug on the children's body.
- Not prescribed for pregnant women, especially in the first three months.
- Breastfeeding is also a contraindication.
- When using the gel, side effects are possible, which are manifested by the following symptoms:
- Metallic taste in the mouth.
- Vertigo and pain in the head area.
- Dermatological rashes.
- Burning.
- Manifestation of nettle rash.
You should pay attention to the negative consequences if the gel gets into your eyes.
How does the gel interact with other medications?
Increases the anticoagulant effect of warfarin. When using disulfiram and dentamet simultaneously, it is possible that the toxic picture may increase, which can provoke the development of neurological symptoms.
The antibacterial activity of metronidazole is reduced when phenobarbital and phenytoin are taken simultaneously, due to increased metabolism of metronidazole.
If the gel is applied externally and cimetidine is used as prescribed during this period, the metabolism of metronidazole will decrease, which will lead to an increase in the level of metronidazole in the blood serum.
Attention! When prescribing dentament gel, it is recommended to tell your doctor about taking any medications. This approach will achieve the maximum therapeutic effect and avoid the development of side effects.
Shelf life, storage and release conditions
The following conditions must be followed to store the drug:
- Maintain temperature conditions (no more than twenty-five degrees)
- Do not freeze.
- Be sure to store in original packaging and with instructions for use.
- The drug should be kept in a closed cabinet so that it is not exposed to direct sunlight and cannot be reached by children.
- Follow the expiration dates written on the packaging.
- Do not use the drug after the expiration date.
The medication can be purchased at pharmacies without a doctor's prescription. The price varies from 105 to 115 rubles.
Analogues and prices
Dentament has a number of similar drugs that have similar pharmacological effects. Among them, experts highlight:
| Drug name | Description | Price |
| Metrodent | A drug with antimicrobial and antiseptic properties with a lemon, pineapple, strawberry scent. Dental gel is prescribed locally for both treatment and prevention of dental diseases. Metronidazole and chlorhexidine are the main active ingredients of the drug. Prescribed for adults and children over sixteen years of age. | from 130.00 to 135.00 rubles |
| Metrohex | Complex antimicrobial medicine. Has antiprotozoal and antibacterial effect. The drug has a detrimental effect on unicellular organisms and anaerobic bacteria. Metrohex has no effect on aerobic microorganisms. The main active components of the gel are metronidazole and chlorhexidine. Indicated for infectious and inflammatory diseases of the oral mucosa in adults and children over 16 years of age. During pregnancy and lactation, the use of this dental product is prohibited. Use is contraindicated in case of individual intolerance to metronidazole, chlorhexidine and nitroimidazole derivatives. | From 223.00 rubles |
| Metrozol Denta | Dental antimicrobial gel. Affects the vital activity of unicellular and bacterial organisms. The drug consists of metronidazole, chlorhexidine and excipients. The medicine is prescribed for many forms of gingivitis, chronic periodantitis, aphthous stomatitis, gangrenous pulpitis and other dental ailments caused by infectious infection. The drug is contraindicated during pregnancy and lactation. | From 225.00 rubles |
Important! When choosing a similar medicine to Dentament, you should carefully consider its main components and contraindications. Changing the drug yourself is strictly prohibited.
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