Medical treatment of bacterial prostatitis. Chronic bacterial prostatitis: treatment, causes, symptoms and diagnosis Causes of chronic prostatitis

Do I need to take antibiotics for prostatitis? Antibacterial therapy is necessary if the nature of the disease is infectious or bacterial. There are five groups of drugs, the action of which is aimed at eliminating the pathogen that caused the development of the disease.

What is prostatitis?

Prostatitis is a disease in which the tissue of the prostate gland becomes inflamed. If the pathology is caused by an infection, the prostatitis is called infectious, if the disease was provoked by bacteria (mycoplasma, chlamydia, trichomonas), it is bacterial. Both types of prostatitis are treated with antibacterial drugs. In the absence of such therapy, the disease progresses.

Spicy

Symptoms of acute prostatitis:

• The temperature rises to 38-39 degrees.
• Pain in the perineum, groin when urinating.
• Bloody, purulent impurities in the urine.
• Pain during ejaculation.
• Liquefaction of semen, blood points, green streaks in seminal fluid.
• Swelling of the perineum.

It becomes painful for a man to sit, walk. He may often run to the toilet to urinate, but very small portions of urine will come out.

Chronic

Chronic prostatitis can develop as a complication after acute. This form of the disease is characterized by a long course and blurred symptoms. The infectious stage lasts about two months, post-infection, in the absence of treatment, several years.

Signs of the disease:

• The presence of impurities in the ejaculate.
• Difficulty urinating.
• Feeling of discomfort in the perineum.
• Violation of potency.
• Lower abdominal pain.
• Unpleasant sensations accompanying urination, ejaculation.

If any symptoms occur, you should consult a doctor. In the initial stages, it is much easier to cure the disease than in an advanced state.

Features of therapy: how to choose the right antibiotic?

For an accurate diagnosis, the doctor takes from the patient. Scraping from the mucosa is sent to the laboratory for culture. For several days, under special conditions, observations are made of the flora growing in the test tube. This type of study allows not only to determine the type of bacteria that has infected a person, but also to give an answer how aggressive they are, how quickly they multiply, what antibacterial drug can destroy them.

Self-treatment for infectious prostatitis is strictly contraindicated! Only after the laboratory has identified the causative agent of the disease, treatment can begin.

Do not choose on your own which antibiotic to take for prostatitis. You can drink medicines only after they are prescribed by a doctor. With unsystematic intake of antibacterial drugs, the development of resistance (resistance of bacteria to the drug) is possible. As a result, the drug will not help, and the disease will only progress.

TOP 8 best antibiotics for the treatment of prostatitis in men

The course of antibiotic therapy for prostatitis is 10-14 days. Dosage and treatment regimen is determined individually. The most effective are antibiotics of the groups of aminoglycosides, macrolides, cephalosporins. Quinols have slightly lower penetration into prostate tissue, but they are also prescribed if sensitivity to this particular type of antibacterial agent is detected.

This is a 3rd generation semi-synthetic aminoglycoside, one of the most advanced broad-spectrum drugs created specifically for the treatment of infectious diseases. Available in the form of solutions for intravenous or intramuscular administration. It must be injected into the blood slowly, so it is often put with the help of droppers.

The drug is well absorbed, relieves swelling and inflammation in the soft tissues. Within 10 hours after entering the body, Amikacin reaches a therapeutic concentration and eliminates most of the pathogenic bacteria.

Antibiotic contraindications:

• Renal failure.
• Intolerance to the components of the drug.
• Allergy to aminoglycosides.
• Inflammation of the auditory nerve.
• Breastfeeding and pregnancy.

Analogues of Amikocin include Gentamicin, which can be produced in other forms - suppositories, ointments.

A macrolide drug used to treat infections of the genitourinary tract and soft tissues. May be administered at normal dosage to elderly patients and patients suffering from renal insufficiency. Roxithromycin is available in tablets; with bacterial prostatitis, men are shown taking 1 tablet 2 times a day. When prescribing the drug to patients with renal insufficiency, the dose should be halved.

The most effective medicine against:

• Legionella pneumophila.
• Chlamydia trachomatis.
• Ureaplasma urealyticum.
• Mycoplasma pneumoniae.

The drug is contraindicated to be taken together with ergotamines. This can lead to alkaloid poisoning and necrosis of leg tissues.

Analogues: Rulil, Josamycin, Roxibid. The choice of drug depends on the severity of the development of the disease and the possible pathogen.

Available in the form of tablets, capsules, granules for suspension. It is a semi-synthetic antibacterial drug belonging to the penicillin group. It cleanses the body of cocci, streptococci, rod, anaerobic microorganisms that are sensitive to penicillin. Indications for the use of Amoxicillin:

• Acute urinary tract infection.
• Chronic bacterial prostatitis.
• Prostatitis complicated by gonorrhea, chlamydia.
• Sepsis.
• Purulent tissue infection.

It is contraindicated to take an antibacterial drug for men allergic to penicillin. Possible side effects: nausea, loose stools, skin rash.

Analogues include Flemoxin, Ecobol, Amosin. Amoxiclav (an antibiotic with clavulonic acid) is also often used to treat prostatitis. It is highly effective, since the acid provides an increase in bactericidal activity.

The drug belongs to the third generation of cephalosporins. It is prescribed for the treatment of severe prolonged chronic prostatitis. The use of Cefotaxime as a second round of antibiotic therapy gives good results, even if the drugs of the penicillin, aminoglycoside, sulfanilamide series have not coped before.

Available in powders, which must be diluted with distillate or saline. It is administered intramuscularly or intravenously. The action of the drug is long in the blood serum of Cefotaxime lasts up to 12 hours. It penetrates well into tissues, quickly reduces the concentration of pathogens.

The drug can be used to treat chronic or acute prostatitis complicated by sexual infection, fungal infection.

• Ceftriaxone.
• Claforan.
• Digital.
• Cefantral.

The antibiotic should be taken with caution in patients with renal and hepatic insufficiency. The drug is contraindicated in patients who have had enterocolitis, suffering from bleeding of any kind.

One of the most used bacteriostatic antibiotics of the tetracycline series. Produced in capsules, absorbed into the systemic circulation through the gastric mucosa. Due to the negative impact on the gastrointestinal tract, it is necessary to take drugs that restore the intestinal flora during antibiotic therapy with this medicine.

Indications for taking Doxycycline:

• Infectious prostatitis.
• Bacterial damage to soft tissues.
• Purulent infections of the urinary tract.
• Mycoplasmosis
• Chlamydia.
• Gonorrhea.
• Chronic prostatitis.

The dose of the drug is selected strictly individually. Not only the type of disease is taken into account, but also the patient's weight, age, gender. The duration of treatment is 1-2 weeks. If necessary, Doxycycline is prescribed in combination, in combination with Gentamicin.

The cheapest analogue of Doxycycline is Tetracycline tablets. The medicine is more expensive - the Dutch Unidox Solutab. It also contains tetracycline, but it acts faster, so the course of treatment with it is shorter, no more than 10 days.

An antimicrobial drug belonging to the group of quinols. Sparfloxacin is a third-generation difluoroquinol used to treat acute and chronic infections of the genitourinary system. Effective for the treatment of bacterial and infectious prostatitis, as well as pathologies complicated by tuberculosis and chlamydia. It can be prescribed after surgery, trauma to the genital organs to prevent infection.

Possible side effects:

• Vasodilation.
• Nausea, vomiting, epigastric pain.
• Violation of the mobility of the tendon of the lower extremities.
• Rash, itching, burning of the skin.
• Dizziness, headache.
• Increased anxiety.
• Sleep disturbance.

Patients under the age of 18 years, the drug is not prescribed. Also, the medicine should not be taken by people with diagnosed photosensitivity.

The drug belongs to the group of oxyquinolines, has a wide spectrum of action. It is prescribed for infectious, bacterial prostatitis, complicated by a fungal infection. The medicine can be prescribed to both an adult man and a child, a teenager. Tablets are also prescribed as a prophylactic.

In chronic infections, a course of Nitroxaline therapy with a break is recommended. The first period of therapy - 14 days, then a break for two weeks and a second course - 14 days. The drug is well tolerated, although side effects in the form of a rash may occur.

Quinole analogues:

• Levofloxacin.
• Ofloxacin.
• Ciprofloxacin.
• Lomefloxacin.
• Norfloxacin.
• Tarivid.

When treating prostatitis with antibiotics, the patient must continue taking the prescribed medication for the period of time prescribed by the doctor. If you stop the course of treatment with the disappearance of unpleasant symptoms, it is possible to renew the disease, so it is not completely destroyed.

Unfortunately, it is a fairly common ailment. According to statistics, almost half of men at one age or another face this problem. The causes of inflammation can be different, and therefore in modern medicine there are several types of this disease. One of them is bacterial prostatitis.

In view of such a large spread of the disease, many men are interested in additional information about it. What are the causes of bacterial inflammation? What are the symptoms to look out for? What methods of modern treatment are the most effective?

What is prostatitis? The main forms of the disease

Before considering the question of what bacterial prostatitis is, it is worth analyzing what the prostate gland, or prostate, is. It is a small organ that is part of the reproductive system. It is located just below the bladder, around the urethra. The prostate produces up to 70 percent of seminal fluid, which then mixes with sperm, which is formed in the testicles. The prostate gland also plays a role in the ejaculation process and maintains an erection. In addition, it affects the retention of urine.

Prostatitis is a disease that is accompanied by an inflammatory process in the tissues of the prostate gland. Depending on the causes of development in modern medicine, several main types of the disease are distinguished:

• acute bacterial prostatitis - inflammation in this case develops against the background of infection of the organ with specific bacteria (for example, chlamydia, gonococci, etc.);
• the chronic form of bacterial prostatitis, as a rule, develops against the background of improper therapy or its absence (the disease lasts more than three months, the well-being period is replaced by exacerbations of the inflammatory process);
• nonspecific prostatitis - the inflammatory process in this disease is caused by activation or is not at all associated with a bacterial infection;
• asymptomatic inflammatory prostatitis occurs without pronounced symptoms, and quite often the inflammatory process subsides on its own.

Causes of bacterial prostatitis

As the name itself says, the inflammatory process in this case is associated with the activity of bacterial microorganisms. The causative agents of bacterial prostatitis quite often penetrate the tissues of the prostate gland if the patient has a sexually transmitted infection. Almost any sexually transmitted disease (for example, gonorrhea, chlamydia) can lead to inflammation of the prostate.

In middle-aged men, opportunistic pathogens, such as E. coli, can also act as a pathogen. A slightly different picture is observed in older patients. The fact is that many men over 50 years old are diagnosed with the so-called benign prostatic hyperplasia (accompanied by tissue growth). With such a pathology, the evacuation of secretory fluid from the prostate is difficult, as a result of which it begins to accumulate inside the gland. The stagnation of the secret leads to the active reproduction of pathogens and, accordingly, to inflammation.

Also, bacterial prostatitis can develop against the background of various pathologies of the genitourinary system. For example, inflammation is much more often diagnosed against the background of bladder obstruction, urinary tract infection, epididymitis, urethritis. The spread and penetration of the infection inside is facilitated by phimosis (fusion of the foreskin). Various perineal injuries, the installation of a urinary catheter, a previous cystoscopy (internal examination of the bladder) or a biopsy can provoke inflammation of the prostate.

Are there risk factors?

As you can see, the causes of inflammation can be different. In addition, there is a group of so-called risk factors, the presence of which increases the likelihood of developing both acute and chronic prostatitis:

Signs of bacterial prostatitis are usually quite characteristic. The disease begins acutely and develops rapidly. Often, patients first notice fever, weakness, body aches, fatigue, muscle pain, nausea, and vomiting.

Along with this, there are also problems with the work of the genitourinary system. The process of urination becomes difficult and painful, the urge becomes more frequent. However, the bladder does not empty completely. The stream during urination becomes weak, while the urine itself acquires a rather unpleasant odor. It may also contain small amounts of blood. There may be pain and burning in the urethra.

Patients often report other symptoms of bacterial prostatitis. In particular, there is pain in the pubic area, which also radiates to the lower back. There may be pain in the testicles and perineal area. Men have problems with erection, and ejaculation is accompanied by painful sensations. Sometimes traces of blood can be seen in semen. Pain is also present during bowel movements.

If you notice these symptoms, you should immediately consult a doctor. The sooner the patient receives qualified medical care, the less likely the disease becomes chronic.

Chronic bacterial prostatitis

It should be noted right away that this form of the disease is quite rare. Chronic bacterial prostatitis may be due to the activity of bacteria that are protected from the effects of drugs, as they are located deep in the tissues of the prostate. In addition, some microorganisms become resistant to broad-spectrum antibiotics.

Exacerbation of chronic bacterial prostatitis is accompanied by almost the same symptoms as the acute form of the disease. There is pain during urination, pain in the abdomen and perineum, the presence of blood in the urine and semen. On the other hand, fever and other signs of intoxication of the body are rarely observed. The exacerbation is replaced by a period of relative well-being - the man feels fine, but there are still some disturbances in the work of the genitourinary system. In particular, patients suffer from increased urge to urinate. There are also problems with erection (sometimes up to serious erectile dysfunction) and a decrease in sexual desire.

Diagnosis of the disease

To begin with, the doctor conducts a physical examination and collects an anamnesis in order to get a complete picture of the symptoms that bother the patient. As a rule, this is enough to suspect prostatitis and prescribe additional tests.

The patient gives blood and urine samples, the analysis of which helps to detect markers of inflammation. You also need a digital rectal gland, which allows the doctor to determine the size, contours, consistency of the organ, the degree of pain and some other parameters. In addition, during prostate massage, you can get samples of her secret, which are then sent for laboratory analysis. Sowing samples helps to determine the type of infection and the degree of its sensitivity to certain drugs.

Further examination is carried out only if there are suspicions of complications. With the help of cystoscopy, the doctor can examine and evaluate the condition of the urinary canal and bladder. Sometimes additional urodynamic tests are performed. Transrectal ultrasound and computed tomography help to better understand the condition of the prostate, to detect the presence of abscesses or stones. If a malignant degeneration of cells is suspected, a prostate biopsy is performed.

Medical treatment of prostatitis

After a complete examination, the doctor will be able to draw up the most effective treatment regimen. As a rule, the first treatment for bacterial prostatitis is antibiotics. In particular, preparations containing tetracycline and ciprofloxacin are considered quite effective antibacterial agents. Depending on the severity of the disease and the type of infection, antibiotic therapy can last from four to six weeks. Sometimes in the first few days, the drugs are administered intravenously, and then they switch to the tablet form. In the chronic form of inflammation, treatment can last up to 12 weeks.

Other drugs are used to treat bacterial prostatitis. In particular, antispasmodics can alleviate the patient's condition, which help to relax the bladder neck and reduce pain during urination. As a rule, Alfuzosin, Terahozin, Silodosin and some others are included in the treatment regimen.

If necessary, the patient is prescribed painkillers, namely non-steroidal anti-inflammatory drugs (Paracetamol, Ibuprofen), which also help relieve fever. The reception of multivitamin complexes, immunomodulators, biostimulants will positively affect the condition of a man.

Other treatments

During the recovery phase, patients are often advised to perform prostate massage. This procedure helps to eliminate fluid stagnation, improve tissue metabolism, increase local immunity, restore the drainage function of the prostate, and also increase blood flow.

Also, during the treatment process, various methods of physiotherapy can be used, in particular:

• magnetotherapy;
• transrectal ultrasound therapy;
• electrical stimulation.

All of the above methods contribute to the normalization of blood circulation and the elimination of stagnant processes.

When is surgery necessary?

Surgery is a last resort. It is used only if long-term drug therapy and other methods of treatment do not give any effect. A partial surgical procedure is usually performed on elderly patients. At a young age, they try to avoid such radical treatment, as it sometimes leads to impotence, enuresis and infertility. The operation is most often prescribed for elderly patients with chronic forms of prostatitis, because they have to suffer from problems with urination and constant pain for many years. If necessary, an additional plastic correction is carried out, which helps to restore the urinary tract, normalize the functioning of the bladder.

Alternative treatments for the disease

Naturally, there are some other, less traditional treatments for prostatitis. For example, sometimes medicinal microclysters, treatment with leeches, acupuncture, massage give a good effect.

Patients with chronic forms of the disease are recommended sanatorium treatment. Also, special physical exercises will positively affect the state of the body, which will help restore blood circulation and eliminate blood stasis in the pelvic organs.

How to treat bacterial prostatitis with folk remedies? To date, there are many means to eliminate the inflammatory process. In particular, the warm decoction of yarrow, horsetail, sage sometimes has a positive effect on the state of the pelvic organs. Special rectal suppositories are also prepared from bee products and medicinal herbs.

In any case, it is worth remembering that before using any remedy, you should definitely consult your doctor.

What are the prognosis for patients?

Does it allow men to achieve good results? It should be said right away that the success of therapy will depend on many factors, including the stage and form of the disease, the age of patients, the presence of concomitant diseases, etc.

Acute bacterial prostatitis responds well to medical treatment. Already a few days after the start of therapy, the patient may notice an improvement in well-being. On the other hand, improper treatment, its absence or termination (for example, quite often men stop taking medications when symptoms disappear without completing the full course) can lead to the development of a chronic form of the disease.

Chronic prostatitis is a disease that is much more difficult to treat. Relapses can happen again and again. And in such cases, doctors often recommend surgery to patients. The results of surgical treatment are usually positive. Again, sometimes the operation is fraught with not too pleasant consequences.

Prostatitis is a common prostate disease that affects many men around the world. Inflammation of the organ is caused by a number of reasons, which is important to consider when determining the tactics of treatment for each individual patient. The scheme is drawn up on an individual basis and very often it is not possible to do without antibacterial drugs.

When is antibiotic treatment indicated?

Prostatitis can be caused by bacteria, or it can be non-infectious in nature. In the latter case, the appointment of antibiotics, as a rule, is not required. They should be taken if the prostatitis has an acute or chronic course against the background of bacterial damage to the prostate gland. In this case, the severity of the symptoms does not matter. Often, chronic bacterial prostatitis generally occurs without any signs indicating the presence of inflammation. In addition, the appointment of antibacterial agents may be due to test therapy, even against the background of abacterial inflammation.

It is very important to follow all the points of diagnosing prostatitis in order to find out the cause of inflammation, identify the pathogenic agent and determine its individual sensitivity to a particular drug:

The first stage of diagnostic studies. The first stage includes:

Blood sampling for clinical analysis.

Urine sampling for bacterial culture, for a three-glass sample.

Sampling of the urethral epithelium for the detection of STIs by PCR, including chlamydia, mycoplasmosis, gonorrhea, etc.

Collection of prostate secretion for a comprehensive study.

Ultrasound examination of the prostate.

Blood sampling to determine the level of PSA in it, which allows you to exclude.

Second phase diagnostic studies: When the content of leukocytes in the prostatic secret does not exceed 25, then testing with the drug Omnic (tamsulosin) is indicated. It is taken for a week, after which the secret is taken for analysis again.

The results of the examination determine the type of prostatitis

Abacterial prostatitis. When there is no leukocyte jump even while taking Omnic, and no bacteria are found in the cultures, then inflammation of the prostate gland is defined as non-bacterial. This condition is called pelvic pain syndrome, which requires symptomatic therapy.

At the same time, the patient is waiting for the result of tests for tuberculosis, which will be ready in at least 10 weeks. If they are positive, then the patient is placed in an anti-tuberculosis dispensary (in the urological department).

Tuberculous prostatitis. You can determine the disease by performing a biopsy of the prostate. The infection most often affects not only the prostate gland, but also the epididymis, urinary system, seminal vesicles. Despite the fact that in the Russian Federation tuberculosis is becoming epidemic, and not only the lungs, but also other organs are affected, the diagnosis of this disease presents certain difficulties. There is also a danger in the fact that special forms of the disease caused by therapy-resistant bacteria are becoming more common.

Tuberculosis of the genitourinary system of men often develops latently, without giving acute symptoms. Laboratory studies can give a false negative result, especially if a man takes antibiotics for prostatitis from the fluoroquinlone group.

Symptoms that may indicate prostate tuberculosis are low-grade fever, aching or burning pains in the perineal region, in the lumbosacral region, and increased fatigue. The age of patients in whom tuberculous prostatitis is most often detected is in the range between 20-40 years.

Bacterial infectious prostatitis. In the event that the analysis of the secret of the prostate indicates leukocytosis with an increase in the number of leukocytes over 25, and taking Omnic makes this figure higher, then it makes sense to talk about bacterial or latent infectious prostatitis. Antibacterial therapy in this case is carried out without fail.

The PCR method allows you to identify the existing pathogens of sexual infection already a day later, so the doctor will be able to recommend taking this or that drug at the next visit. The drug of choice remains the agent for which the established flora has maximum sensitivity, or an antibiotic is prescribed that is active against most pathogenic agents.

If there is no effect from the ongoing treatment, then it is necessary to wait for the result of bacteriological seeding, which makes it possible to more accurately determine the choice of remedy.

What antibiotics are most effective for prostatitis?

It is impossible to determine any specific antibiotic for bacterial prostatitis that would help all men without exception in the treatment. It all depends on the sensitivity of the microbes that caused the disease in each case.

Self-therapy with the use of antibacterial and other means, self-diagnosis of the disease is impossible. An effective drug can only be selected if a specific bacterial agent is known, after doctors have established its susceptibility to drugs. Only the doctor decides how long the treatment will need to be carried out, what doses of the drug are needed for this. Most often, specialists prescribe broad-spectrum drugs.

If specific bacteria are not detected, then medication is recommended based on culture of prostate secretion. There, nonspecific streptococci and staphylococci are most often detected.

Treatment involves an integrated approach and does not last for 30-60 days:

An antibiotic is prescribed.

NSAIDs are indicated.

You should take funds aimed at normalizing blood circulation.

Immunostimulating therapy is carried out.

Vitamin complexes or monovitamins are prescribed.

In some cases, phytotherapy is prescribed.

Thermal microwave therapy, prostate massage can be performed only when tuberculosis is excluded. Otherwise, the disease may worsen, which will worsen the patient's condition.

Sedative drugs, antidepressants are recommended for men with chronic prostatitis against the background, with a deterioration in the quality of life. In this case, psychotropic drugs are auxiliary.

Depending on which pathogen is identified, one or another antibiotic for prostatitis is selected.

The sensitivity of pathogenic microorganisms to antibacterial drugs is presented in the table:

	Tetracycline drugs	Preparations of the penicillin group	Cephalosporins	Macrolides	Fluoroquinolones
Mycoplasmas
Ureaplasmas
Chlamydia
Gonococci
Enterococci
Enterobacteria
Klebsiella
Pseudomanad
tuberculosis bacterium
coli

It should not be excluded that the cause of the development of inflammation of the prostate gland are mycotic microorganisms. Therefore, in complex therapy, it is possible to prescribe the following drugs: Safocid, Fluconazole, Azithromycin and Seknidazole.

List of antibiotics for prostatitis: pros and cons

Preparations from the group of fluoroquinolones are prescribed by modern practicing urologists more often than others. They show high efficiency in the treatment of chronic bacterial prostatitis, however, they can have a negative impact on the functioning of the brain, cause mental disorders, and reduce the resistance of skin cells to ultraviolet radiation. Before starting treatment with fluoroquinolones, it is necessary to make sure that the Koch stick is absent in the body. Medicines of this group are used to treat tuberculosis, but it should be complex with the inclusion of anti-tuberculosis drugs in the therapeutic regimen. Therapy with only fluoroquinolones will lead to the fact that tuberculosis bacteria will develop drug resistance and it will be very difficult to get rid of them in the future. A situation is considered dangerous when a man underwent a course of treatment with fluoroquinolones, his condition returned to normal, and after 30-60 days it worsened again. In this case, repeated tuberculin sampling is necessary.

The following antibiotics of this group are used:

Based on Levofloxacin (Elefloks, Tavanic);

Based on Ciprofloxacin (Cifran, Tsiprobay, Tsiprinol);

Based on Ofloxacin (Zanocin, Ofloxin).

Preparations of the tetracycline group. In recent years, they are used less and less, as they have a large number of side effects. The exception is Doxycycline (Unidox Solutab), which is somewhat easier for patients to tolerate.

Drugs from the group of Cephalosporins are administered intramuscularly - these are Suprax, Cefotaxime, Ceftriaxone, Kefadim, Klaforan, Cefspan and others.

Of the drugs of the penicillin series, Amoxiclav, Flemoklav solutab, Augmentin, Flemoxin solutab are prescribed.

With regard to macrolides, studies that would confirm their effectiveness against bacterial prostatitis have not been conducted. However, logically speaking, macrolides are agents of low toxicity, with high activity against certain bacteria, especially against mycoplasma and chlamydia. Therefore, theoretically, their use in inflammation of the prostate is possible. These are means such as: Fromilid with the active ingredient Clarithromycin and Sumamed, or Zitrolide with the active ingredient Azithromycin.

In the treatment of prostatitis, it is very important that the drug can penetrate into the tissues of the prostate and accumulate there in the organ. Such capabilities are possessed by drugs of the group of fluoroquinolones, macrolides and aminoglycosides (Gentamicin). If the patient arrives with an acute stage of inflammation, then for its speedy elimination it is possible to use several antibiotics at once for prostatitis.

Eleflox is an antibacterial drug from the group of fluoroquinolones with the main active ingredient Levofloxacin. The drug is available in tablets and in solution for infusion. Eleflox is the drug of choice in the treatment of prostatitis.

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The main advantage of the drug Elefloks lies in its high activity against gram-positive and gram-negative bacteria, which most often provoke the development of prostatitis. Among such microorganisms: E. coli, Klebsiella, Proteus mirabilis, fecal enterococcus, Pseudomonas aeruginosa, ureaplasma, chlamydia and mycoplasma. Thanks to taking the drug Elefloks, the improvement occurs after a few days.

Another advantage of the drug is its proven microbiological and clinical efficacy. It has a high pharmacokinetic profile and penetrates well into the tissues of the prostate gland, which is essential for the successful treatment of prostatitis.

Eleflox based on Levofloxacin is a second-generation fluoroquinolone drug, it is twice as well tolerated by patients than first-generation fluoroquinolones, and also shows high efficiency against penicillin-resistant bacterial strains. This is a significant plus of the drug.

It has been established that after taking the drug, its concentration in the prostate gland is 4 times higher than the concentration in the blood plasma. As a result, the bacteria inhabiting the tissues of the prostate quickly die, since Eleflox causes profound changes in the cytoplasm, membranes and cell wall of pathogenic microorganisms.

The next advantage of the drug Elefloks is that it is available both in the form of tablets and in the form of a solution for infusion. Therefore, you can choose the method of taking the drug, which will be optimal for a particular patient.

Minuses

The main disadvantage of the drug is the presence of contraindications to its use. It is strictly forbidden to take it for the treatment of prostatitis in the event that a person has a suspicion of tuberculosis. The fact is that fluoroquinolones are included in the treatment regimen for tuberculosis, but effective therapy will require the simultaneous administration of several antibiotics at once. If a person infected with Koch's bacillus takes Eleflox to treat prostatitis, then further anti-tuberculosis therapy may not work. Other contraindications include epilepsy, hypersensitivity to fluoroquinolones in general, and age under 18 years of age.

One of the disadvantages of the drug is its high cost, which starts from 700 rubles and more for tablets, and from 420 rubles for a solution.

It is worth noting such a minus of the drug Elefloks as side effects that may develop against the background of its use. Among them are various allergic reactions, nausea, diarrhea, headaches, dizziness, increased heart rate, etc.

When treating with Eleflox, it should be remembered that it is able to interact with other drugs, which can also be attributed to its disadvantages. For example, when taken simultaneously with glucocorticosteroids, the risk of tendon rupture increases. Therefore, it is necessary to start treatment with this antibacterial drug only after a medical examination.

Tavanic is an antibacterial drug for the treatment of prostatitis with the main active ingredient Levofloxacin. Tavanic belongs to the fluoroquinolones.

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The main advantage of Tavanic is its wide spectrum of antibacterial activity. Moreover, it is effective against most bacteria that are the causative agents of infectious prostatitis. These are not only gram-positive and gram-negative microorganisms, ureaplasmas, mycoplasmas, gonococci, but also anaerobes. Sensitivity to the drug Tavanic has Escherichia coli, which very often causes inflammation of the prostate.

Tavanic belongs to the second generation fluoroquinolone antibiotics, that is, it shows a higher activity in terms of getting rid of various bacteria and is better tolerated by patients.

The drug is produced by the well-known group of companies Sanofi Aventis, which is one of the global leaders in the field of healthcare. This means that the drug meets all international safety requirements and has passed all the necessary clinical trials.

Another advantage of Tavanic is its high ability to penetrate and accumulate in prostate tissues. Moreover, the intracellular concentration of the main active substance is 8-9 times higher than its extracellular concentration. This allows you to effectively use the drug Tavanic for the treatment of intracellular pathogens of prostatitis - chlamydia, ureaplasma and mycoplasma.

It is worth noting such a plus of the Tavanic drug as the presence of several dosage forms: it is available in tablets with various dosages and in the form of a solution for infusion.

Minuses

The main disadvantage of Tavanic is the presence of contraindications to its use. These include: epilepsy, hypersensitivity to fluoroquinolones, age under 18 years, the presence of tendon damage during treatment with quinolones. Do not prescribe a drug for the treatment of prostatitis to people with suspected tuberculosis. Therefore, if there is any doubt, it is necessary to take appropriate tests.

The disadvantages of the drug include side effects. More often than others, there are: diarrhea, nausea, headache, drowsiness, sleep disturbance, asthenia, an increase in hepatic transaminases is possible. Other side effects are observed with less frequency - these are fever, hepatic reactions, tendon ruptures, etc.

With caution, the drug should be taken against the background of treatment with other drugs. For example, with NSAIDs, glucocorticosteroids, vitamin K antagonists, Cimetidine, etc.

The last disadvantage of the drug Tavanic can be considered its high cost. So, the price for 5 tablets with a dosage of 500 mg starts from 590 rubles. A bottle with a solution for infusion costs from 1250 rubles.

Cifran is an antibacterial drug from the group of fluoroquinolones, with the main active ingredient Ciprofloxacin. Cifran is the drug of choice in the treatment of prostatitis.

pros

The main advantage of the drug Cifran is its high activity against bacteria that cause inflammation of the prostate gland. It is prescribed for prostatitis caused by microbes of the intestinal group (E. coli, Klebsiella, Proteus, Enterobacter, etc.). Trichomonas, ureaplasmas, Staphylococcus aureus, chlamydia trachomatis, anaerobic bacteria and other pathogenic flora that can provoke the development of inflammation of the prostate gland respond well to Cifran.

The advantage of the drug Tsifran is that it begins to act very quickly. This is possible due to the high bioavailability of the drug, which accumulates in high concentrations in the tissues of the prostate. Under such conditions, the bacteria lose their viability, and recovery occurs.

Due to the clinically proven efficacy of Cifran in the treatment of prostatitis, it is prescribed not only to get rid of the acute, but also the chronic form of the disease. And Tsifran more effectively fights Pseudomonas aeruginosa, compared with drugs based on Levofloxacin.

The advantages of the drug include its relatively low cost, which is about 300 rubles.

Minuses

Cifran, with the main active ingredient Ciprofloxacin, belongs to the first generation fluoroquinolones, while there are already 2nd generation drugs. Therefore, when treating prostatitis with Cifran, there is a higher risk that the bacteria will become resistant to it. In addition, first-generation fluoroquinolones are worse tolerated by patients than second-generation drugs. This can be attributed to the disadvantages of the drug.

Cifran has moderate activity against atypical pathogens of inflammation in the prostate gland, which somewhat limits its scope. The disadvantages of the drug Cifran include the presence of side effects, including: nausea, diarrhea, skin rash, candidiasis of the mucous membranes, hepatitis, eosinophilia, arthralgia, headaches, sweating, urticaria, taste disturbances, etc.

The drug should not be used to treat children under 18 years of age, to treat patients with pseudomembranous colitis. It is not prescribed for people with a history of hypersensitivity to fluoroquinolones.

Tsiprobay is the antibacterial drug of choice in the treatment of prostatitis. It belongs to the group of fluoroquinolones, the main active ingredient in it is Levofloxacin.

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Cyprobay is an antibacterial drug that has a detrimental effect on gram-positive and, to a greater extent, gram-negative bacteria, which are common causative agents of prostatitis. It has been proven to be highly effective against chlamydia, mycoplasma, ureaplasma, gram-negative bacteria of the intestinal group, anaerobes.

The drug, when taken orally, is rapidly absorbed and well distributed throughout the tissues, accumulating in high concentrations in the prostate gland. This leads to the death of the pathogenic flora and the rapid elimination of the disease.

Another advantage of the drug is two forms of release: a solution for infusion and tablets, which allows for the treatment of prostatitis more effectively, starting with intravenous administration of the drug, and then moving on to oral administration.

The drug is produced by the well-known pharmaceutical company Bayer, which has been creating and selling medicines since 1863. Therefore, you can be sure that Tsiprobay is a high-quality antibiotic that has passed all the necessary clinical trials.

The price of the drug is relatively low; for a package of tablets in a dosage of 500 mg, you will have to pay about 370 rubles.

Minuses

Cyprobay is a first generation fluoroquinolone. Therefore, the risk of developing resistance in bacteria to the drug is higher than to second-generation fluoroquinolones. This can be considered the main disadvantage of the drug.

The second disadvantage of the drug Tsiprobay is the presence of contraindications to its use, including: age under 18, epilepsy, organic brain damage, mental illness. With caution, the drug is prescribed to the elderly.

The third disadvantage of the drug can be called the presence of side effects - these are fungal lesions of the mucous membranes, eosinophilia, loss of appetite, diarrhea and nausea, headache, taste distortion, sleep disturbance, etc.

Before starting treatment, you should definitely visit a doctor, as the drug is able to interact with other drugs, which can provoke an increase in side effects.

Tsiprinol is an antibacterial drug with the main active ingredient Ciprofloxacin. Tsiprinol belongs to the group of first-generation fluoroquinolones and is the drug of choice for the treatment of prostatitis.

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The main advantage of the drug Tsiprinol is its pronounced bacteriostatic activity against most pathogens of prostatitis. The drug has a wide spectrum of action, inhibiting the enzyme DNA gyrase of bacteria, which makes it impossible to start the process of protein synthesis in their cells. As a result, the pathogenic flora dies.

The drug has low toxicity to humans, since DNA gyrase is absent in its cells.

Another plus of Tsiprinol is its high activity against bacteria that are resistant to aminoglycosides, penicillins, cephalosporins and tetracyclines. Prostatitis caused by gram-negative bacteria (enterobacteria, E. coli, shigella, pseudomonas, moxarella, legionella, listeria, etc.) responds well to treatment with Tsiprinol. Some gram-positive aerobes are sensitive to the drug: staphylococci and streptococci.

An important advantage of the drug is that it has a high bioavailability and accumulates in high concentrations in the tissues of the prostate gland. Cyprinol is able to destroy bacteria that multiply and that are at rest.

Another advantage of the drug Tsiprinol is its affordable price. So. For 10 tablets of 500 mg, you will have to pay about 120 rubles.

Minuses

The main disadvantage of the drug is that some bacteria may not be sensitive to it. For example, corynebacteria, fragilis bacteroids, some types of Pseudomonas, treponema. Bacteria resistant to methicillin are resistant to Tsiprinol. The drug is a first-generation fluoroquinolone, while second-generation antibiotics have been developed that have higher antimicrobial activity and are better tolerated by patients.

Another disadvantage of the drug is that it has a number of side effects. Most often, patients complain of nausea and diarrhea, although the development of a fungal infection, pseudomembranous colitis is not excluded, sometimes allergic reactions occur, up to angioedema and anaphylactic shock. Changes are possible on the part of metabolism, on the part of the nervous system, organs of vision, etc. However, the frequency of side effects is not high and most often Tsiprinol is well tolerated by patients.

It is worth noting such a minus of the drug as contraindications to its use. It is strictly forbidden to prescribe Tsiprinol for the treatment of prostatitis in people with hypersensitivity to fluoroquinolones, in patients with chronic renal failure, in children and adolescents under 18 years of age.

Tsiprinol is able to interact with other drugs. For example, it should not be taken with tizanidine, as this may cause a drop in blood pressure levels.

Zanocin is a broad-spectrum antibacterial drug with the main active ingredient - Ofloxacin. Zanocin is a second-generation fluoroquinolone.

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Zanocin is the drug of choice in the treatment of prostatitis. The main active ingredient perfectly penetrates into the tissues and secretion of the prostate gland and covers a huge range of prostatitis pathogens.

An important advantage of Zanocin is its high activity against most gram-negative microbes of the intestinal group (E. coli, Klebsiella, Proteus, Enterobacter), as well as against Pseudomonas, Trichomonas, Ureaplasma, Mycoplasma and other pathogens of prostatitis. Sensitive to Zanocin strains of bacteria that are resistant to antibiotics of other groups.

The undoubted advantage of Zanocin is that it can be used during complex antibacterial therapy, that is, it is prescribed with cephalosporins, macrolides, beta-lactam antibiotics.

The drug is available in two forms: in tablets and in the form of a solution for infusion. At the same time, it has an equivalent bioavailability for oral and parenteral administration, so there is no need for dose adjustment. This is a significant plus of the drug, for example, compared with drugs based on Ciprofloxacin.

The price range of the drug is average. So, Zanocin tablets at a dosage of 400 mg can be purchased at a price of about 314 rubles.

Minuses

Although Zanocin is the drug of choice for treating prostatitis, some bacterial strains may be resistant to it. For example, Escherichia coli gives resistance to Zanocin in 4.3% of cases in Russia as a whole. In some regions, this figure is higher, for example, in St. Petersburg it is 13%. Therefore, it is recommended to use preparations based on Ofloxacin in the treatment of uncomplicated prostatitis.

Another disadvantage of the drug is the presence of side effects, including: nausea, vomiting, diarrhea, fatigue, increased intracranial pressure, tachycardia, anemia, leukopenia, impaired kidney function, etc.

The next drawback of the drug is its ability to interact with other drugs, which often leads to an increase in their side effects. For example, you can not combine taking Zanocin and Theophylline, as this will lead to a sharp drop in blood pressure. And the simultaneous use of Zanocin with NSAIDs increases its side effects on the central nervous system.

Zanocin is not prescribed for the treatment of prostatitis in people with hypersensitivity to fluoroquinolones, it should not be used to treat children and adolescents under the age of 18 years.

Ofloxin is a broad-spectrum antibacterial drug related to second-generation fluoroquinolones. The main active ingredient is Ofloxacin.

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Another advantage of Ofloxin is its high bioavailability, which ranges from 95 to 100%. In addition, it does not differ between oral and parenteral administration, which does not require dose changes when changing the route of administration. This is quite relevant for the treatment of prostatitis, since a stepwise scheme is often used.

The next advantage of the drug is that it perfectly hits the target organs. In this case, we are talking about the tissue and the secret of the prostate gland.

Another advantage of the drug: Ofloxin does not have a pathogenic effect on bifidus and lactobacilli, and therefore does not contribute to the violation of the intestinal microflora.

It should be noted that, unlike most other fluoroquinolones, Ofloxin does not give any clinically significant phototoxic effect and does not interact with Theophylline.

The price of Ofloxin is very acceptable, for 10 tablets at a dosage of 200 mg you will need to pay about 180 rubles.

Minuses

The main disadvantage of Ofloxin is the presence of side effects that occur on average in 4-8% of patients. Most often they are associated with disruption of the digestive tract, central nervous system and skin. Among them: nausea, vomiting, gastralgia, headaches, sleep disturbance, increased anxiety, skin rash and itching, urticaria, petechiae, papular rash, etc.

Another disadvantage of the drug is that it is not used to treat people with hypersensitivity to fluoroquinolones, to treat children and adolescents under 18 years of age.

Some strains of Escherichia coli are resistant to Ofloxin (about 4.3% of cases), which can lead to ineffective use of the drug for the treatment of prostatitis. Moderate resistance to Ofloksin is shown by some strains of gram-positive bacteria.

Unidox Solutab is a broad-spectrum antibacterial drug from the tetracycline group. The main active ingredient is Doxycycline.

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Unidox Solutab is practically the only drug from the tetracycline group that modern proctologists use to treat prostatitis, since it is more easily tolerated by patients than others.

Unidox Solutab has antibacterial activity against ureaplasma, mycoplasma, chlamydia, Klebsiella, enterobacteria, Pseudomonas and E. coli.

Another advantage of the drug is its high bioavailability, which is 100%. Already half an hour after the first dose, the dose of the drug substance that is necessary to provide a therapeutic effect will be concentrated in the prostate gland.

Unidox Solutab is available in the form of dispersible tablets, which makes taking the drug very convenient.

The price of the drug is not very high and is about 350 rubles for a pack of 10 tablets.

Minuses

The main disadvantage of Unidox Solutab is that such possible pathogens of prostatitis as Proteus, Serrata, some strains of Pseudomonas, Acinetobacter, symbiotic enterococci are resistant to it. In addition, resistance to Unidox Solutab, which occurs in the treatment of prostatitis, will be extended to other drugs from the tetracycline group. Therefore, in some cases, it is required to replace the drug with a radically different antibiotic.

Another disadvantage of the drug is that it is not prescribed for the treatment of people with severe disorders of the kidneys and liver, with porphyrin disease, with hypersensitivity to tetracyclines.

Another disadvantage of Unidox Solutab is the side effects that may occur after taking it, including: anorexia, nausea, diarrhea, enterocolitis, allergic reactions, liver damage, anemia, eosinophilia, increased ICP, etc.

Suprax is a broad-spectrum antibacterial drug from the group of cephalosporins (3rd generation of drugs). The main active ingredient is cefixime.

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The main advantage of Suprax in the treatment of prostatitis is its high antibacterial activity against gram-negative bacterial strains. Suprax allows you to get rid of prostatitis caused by gonococci, enterobacteria, Proteus, Klebsiella and E. coli.

Suprax is a drug for oral administration. It has three forms of release - in capsules, in tablets, in suspension, so it can be used for treatment not only in a hospital, but also at home.

The drug is produced by the well-known company Astellas, which is one of the 20 leading pharmaceutical companies in the world. Therefore, the drug has passed all the necessary clinical trials, which is its undoubted advantage.

Taking the drug Suprax does not have a pronounced effect on the human immune system, does not reduce the protective functions of the body, which is also its advantage over some other antibiotics.

Minuses

Suprax does not have high permeability in the prostate tissue, which is a significant disadvantage of the drug in the treatment of prostatitis.

Another drawback of the drug is the insensitivity to it of bacteria such as: ureaplasma, mycoplasma, chlamydia, enterococci, pseudomonads, seration, listeria. Therefore, if prostatitis was caused by one of these microorganisms, the therapeutic effect cannot be achieved. Or you will have to use Suprax in combination with other antibiotics.

Another disadvantage of the drug is its high cost. So, for a package with 6 capsules at a dosage of 400 mg, you will have to pay about 700-800 rubles.

It is worth noting such a drawback of the drug as the presence of side effects. Perhaps the occurrence of allergic reactions, the appearance of dry mouth, the development of diarrhea, nausea, flatulence, vomiting, dizziness and headaches.

Cefotaxime is a broad-spectrum antibiotic from the group of third-generation cephalosporins with the main active ingredient Cefotaxime.

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The main advantage of Cefotaxime is its extended spectrum of action compared to previous generations of cephalosporins, as it has increased resistance to beta-lactams. Therefore, Cefotaxime may be prescribed for the treatment of complicated prostatitis.

The drug is active against most bacteria that provoke prostatitis, including: gonococci, enterobacteria, Klebsiella, Proteus, staphylococci. Cefotaxime can help to get rid of the disease, even when there is no effect from treatment with tetracyclines, penicillins and aminoglycosides. Often it is used in the complex therapy of prostatitis.

It should also be noted such a plus of the drug as the absence of contraindications to its use, with the exception of hypersensitivity reactions to cephalosporins.

The price of the drug is not high, so a bottle with 1 g of the active substance can be purchased for 20-40 rubles.

Minuses

One of the disadvantages of the drug can be called the fact that it is allowed to be used only for parenteral administration. The drug is not available in tablets or capsules, that is, oral administration is not available.

Treatment with Cefotaxime is carried out only in a hospital setting.

Another disadvantage of Cefotaxime is the presence of side effects, including: local reactions to the administration of the drug, skin rashes, disorders of the digestive tract, pseudomembranous colitis, etc.

Ceftriaxone is a broad-spectrum antibiotic from the group of third-generation fluoroquinolones.

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The main advantage of the drug is that it has a pronounced bactericidal effect. It can be used to treat prostatitis caused by Gram-positive and Gram-negative bacteria.

Another plus of Ceftriaxone is its increased resistance to beta-lactamase enzymes produced by most pathogenic microorganisms. This means that the drug will be effective even where other antibacterial agents (penicillins and even cephalosporins of previous generations) fail.

When administered parenterally, the drug penetrates well into the tissues and fluids of the prostate. Moreover, the drug has practically no contraindications, with the exception of the possibility of a hypersensitivity reaction to cephalosporins.

The price of Ceftriaxone is not high. The average cost of 1 bottle with 1 g of the active substance varies between 22-30 rubles.

Minuses

One of the disadvantages of the drug is that it can only be used for parenteral use. Therefore, treatment with Ceftriaxone is carried out only in a hospital setting.

Another disadvantage of the drug is the possibility of side effects after its administration. These include: diarrhea, nausea, eosinophilia, allergic, urticaria, headaches, congestion in the gallbladder.

Klaforan is a broad-spectrum antibiotic from the group of third-generation cephalosporins. The main active ingredient is Cefotaxime.

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The main advantage of the drug Klaforan in the treatment of prostatitis is that it has bactericidal properties against gram-negative and gram-positive pathogenic flora. Unlike some other cephalosporins, Klaforan has a detrimental effect on bacteria that synthesize beta-lactamase. Therefore, it can be used to treat patients who have not responded to tetracycline and other antibiotic therapy.

The drug is produced by the well-known pharmaceutical company Sanofi Aventis, which means that it has a high degree of purification.

The drug has practically no contraindications. It should not be used solely for the treatment of patients with hypersensitivity to cephalosporins in general.

Minuses

One of the main disadvantages of the drug is that it can be used exclusively for parenteral administration. Therefore, Klaforan treatment is carried out only in a hospital setting.

It is also worth noting such a drawback of the drug as its relatively high price compared to other 3rd generation cephalosporins. So, 1 bottle with a dosage of 1 g will cost from 155 rubles.

The disadvantages of the drug include the possibility of side effects, including: disorders of the digestive system (nausea, loss of appetite), allergic reactions, arrhythmia, fever, pain at the injection site, etc.

Amoxiclav is a broad-spectrum antibiotic, with the main active ingredient amoxicillin + clavulanic acid. The drug belongs to the group of penicillins.

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The main advantage of Amoxiclav in the treatment of prostatitis is that it effectively fights bacteria that produce beta-lactamase enzymes. This allows you to have a pronounced bactericidal effect against a wide range of pathogenic microorganisms.

To date, Amoxiclav is one of the most effective antibiotics for the treatment of prostatitis among penicillins. It allows you to get rid of such bacteria that cause prostatitis, such as: gonococci, enterobacteria, enterococci, Klebsiella, Proteus, seracia, E. coli and some others.

The drug was developed by the famous pharmaceutical company SmithKline Beecham Pharmaceuticals. Therefore, you can not worry about the quality and safety of the drug.

Another advantage of Amoxiclav is its selective activity against bacterial cells. That is, it recognizes pathogenic cells and destroys them, while healthy tissues are not damaged.

The advantage of the drug is its relatively low price. So, a package of Amoxiclav tablets 20 pieces in a dosage of 500 mg can be purchased for 300-400 rubles.

Minuses

The main disadvantage of the drug in the treatment of prostatitis can be considered its low efficiency against bacterial strains such as: ureaplasma, mycoplasma, chlamydia and pseudomonads. Therefore, although Amoxiclav is a clavulanic acid protected semi-synthetic aminopenicillin, it may not be effective in the treatment of prostatitis caused by atypical or resistant flora.

Another obvious disadvantage of Amoxiclav is that it can provoke a number of side effects, including: nausea, diarrhea, vomiting, heartburn, liver and kidney disorders, allergic reactions, fungal infection, etc.

Flemoclav Solutab is an antibiotic from the penicillin group with the main active ingredient Amoxicillin + potassium clavulanate.

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Flemoklav Solutab, like Amoxiclav, is a protected penicillin, which ensures its high antibacterial activity against most bacteria that can provoke the development of prostatitis.

An important advantage of the drug Flemoklav solutab is that it is available in the form of dispersible tablets. This makes it convenient to take for some groups of patients. Moreover, this form of release has a gentle effect on the gastric mucosa and is more easily absorbed by the body.

It is impossible not to mention such a plus of the drug Flemoklav solutab, as its ability to fight beta-lactamase strains of bacteria that are resistant to a number of other antibiotics.

Minuses

Among the disadvantages of the drug Flemoklav solutab is its high cost compared to other forms of penicillins with clavulanic acid. So, for the packaging of the drug, it will be necessary to pay 400-500 rubles.

Also, the disadvantages of the drug include the presence of contraindications to its use, including: hypersensitivity to the components of the drug, jaundice, liver dysfunction, infectious mononucleosis, lymphocytic leukemia.

It is worth noting such a minus of the drug as the presence of side effects that may occur while taking it. Most often, patients suffer from diarrhea and nausea, as well as from fungal infections that occur against the background. It is also possible to develop allergic reactions, exanthema, candidiasis, hepatitis and other undesirable reactions.

Augmentin is a broad-spectrum antibiotic containing Amoxiclav and clavulanic acid.

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The main advantage of Augmentin is its resistance to bacteria that produce beta-lactamase enzymes, which is possible due to clavulanic acid in its composition. Augmentin acts against many strains of gram-positive and gram-negative bacteria that can provoke the development of prostatitis.

The drug is available in tablets, in the form of a powder for the preparation of a suspension, in the form of a powder for intravenous and intramuscular administration. This is also an important advantage of the drug Augmentin, as it makes it possible to use it for different groups of patients.

Minuses

One of the disadvantages of the drug is its high cost, which, depending on the form of release of the drug, can reach 1800 rubles.

The disadvantages of Augmentin include its resistance to some atypical pathogens of prostatitis, including strains of mycoplasma, ureaplasma, chlamydia, pseudomonas, as well as some gram-negative anaerobes.

Separately, it should be noted the side effects that may occur while taking Augmentin. Most often, patients complain of diarrhea, a feeling of nausea and fungal infections. Although there may be a violation of the work of such organs and systems as: the central nervous system, the lymphatic system, the liver, gallbladder, blood vessels, urinary tract, skin.

Flemoxin Solutab is a broad-spectrum antibiotic based on Amoxicillin. The drug belongs to the group of penicillins.

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Flemoxin Solutab has activity against a number of gram-negative and gram-positive bacteria that can cause prostatitis. These are some strains of staphylococci, streptococci. Moderate activity shows the drug against enterococci, Proteus, Salmonella, Shigella.

The drug is released in the form of dispersible tablets, which makes it convenient to take it for some categories of patients. In addition, the trihydrate is better absorbed by the gastrointestinal tract and does not irritate the gastric mucosa.

The drug is produced by Astellas, which has proven itself in the pharmacological market. This means that the drug meets all global safety standards.

The drug is in the middle price range. It can be purchased at a price of 230 rubles and above, depending on the dosage.

Minuses

The drug is not effective against bacteria producing beta-lactamase enzymes, against Pseudomonas, Enterobacter, Ureaplasma, Mycoplasma, Chlamydia and some other pathogenic microorganisms. Therefore, the treatment of prostatitis with Flemoxin Solutab alone may not be effective. This is the main disadvantage of the drug.

It is also worth noting the presence of side effects that may occur when taking it: a change in taste, vomiting, diarrhea, nephritis, agranulocytosis, skin reactions, etc.

Gentamicin is a broad-spectrum antibacterial drug from the group of aminoglycosides.

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The main advantage of the drug is its high antibacterial activity against gram-negative flora, which can provoke the development of prostatitis, for example, against Salmonella, Enterobacter, Klebsiella, Proteus, Pseudomonas, etc.

The drug is rapidly absorbed into the blood and already an hour after its administration in plasma, its therapeutic concentration is observed.

A significant advantage of the drug is its low price. So, a package of 10 ampoules can be purchased for only 40-50 rubles.

Minuses

One of the significant disadvantages of the drug Gentamicin is its limited spectrum of action, that is, it will be ineffective against some strains of bacteria that cause prostatitis. Therefore, it is most often used in a complex treatment regimen for inflammation of the prostate.

The disadvantages of the drug include the fact that it is administered only parenterally. Oral administration of the drug is not available.

Also a minus of Gentamicin are its numerous side effects, including: vomiting, nausea, anemia, leukopenia, oliguria, headaches, increased drowsiness, hearing impairment, etc.

The drug has contraindications for use, for example, neuritis of the auditory nerve, impaired renal function.

Education: A diploma in the specialty "Andrology" was obtained after completing residency at the Department of Endoscopic Urology of the Russian Medical Academy of Postgraduate Education at the Urological Center of the Central Clinical Hospital No. 1 of Russian Railways (2007). Postgraduate studies were completed here in 2010.

Almost every second man faces prostatitis at different ages. This disease is associated with an inflammatory process in the prostate, which can be caused by congestive processes in the pelvic region, various infections, etc. In the case when the result of the analysis showed the presence of pathogens in the secretion of the prostate gland, the doctor diagnoses bacterial prostatitis. Why does the disease develop and how is it treated?

Based on the name, it becomes clear that the main reason for the development of the disease is the entry of bacteria into the prostate. The causative agents can be:

• Escherichia and Pseudomonas aeruginosa.
• Staphylococcus.
• Enterococcus.

• Klebsiella.
• Enterobacter.

• Proteus.
• Sexually transmitted infections.

Many pathogenic microorganisms are always present in the human body without harming it. However, when favorable conditions arise, the infection begins to actively develop, causing the disease. Conditions favorable for bacteria include:

1. Diseases of the urinary tract.
2. Bacterial infections that develop in the body and can enter the prostate through the blood or lymph fluid.
3. Phimosis of the prostate.
4. Acute epididymitis.
5. Urethral catheterization.

Dear readers, we invite you to watch the video of the immunologist Georgy Alexandrovich Ermakov about the causes and symptoms of the disease:

1. Reflux (intraprostatic or urethroprostatic) when pathogens enter the prostate.
2. Transurethral operations that were performed without prior antibiotic therapy.

1. Violation of urination due to the abnormal structure of the bladder.
2. Conditions associated with a decrease in immune defense (AIDS, diabetes, hemodialysis procedure, etc.).

When bacteria enter the prostate area, the pathogenic microflora begins to actively develop and an inflammatory process appears in the organ.

Risk factors that increase the likelihood of developing prostatitis include:

The main causes of inflammation of the prostate gland

• Prolonged sexual abstinence.
• Having bad habits.
• Weakened immunity.

• Wrong nutrition.
• Dehydration of the body.
• A sedentary lifestyle, which leads to the appearance of stagnant processes in the pelvic area.
• Frequent stressful situations.

Symptoms

It is simply impossible not to notice the symptoms of bacterial prostatitis, since this form of the disease begins acutely. The patient is concerned about:

1. An increase in body temperature, accompanied by chills.
2. Pain in the perineum, lower abdomen and lower back.
3. Painful urination. The patient notes pain and, which are especially strongly felt at night.
4. Difficulty urinating, feeling of incomplete emptying of the bladder.
5. Possible constipation due to compression of the anus by an inflamed prostate.
6. Signs of intoxication of the body (headache, general weakness of the body, body aches).
7. Discharge from the urethra.

A short video will tell you about the main symptoms of the disease and methods of therapy:

Symptoms of the disease also vary depending on the stage of bacterial prostatitis:

• At the beginning of the disease, inflammation does not spread beyond the prostate. A man is worried about soreness in the perineum, which can radiate to the sacrum. Urination is frequent and accompanied by pain.
• In the second stage, inflammation passes to the lobules of the prostate gland. In this case, the pain intensifies and can radiate to the anus. Urination is significantly disturbed, up to its complete detention.

• With the advanced form of bacterial prostatitis, the inflammation spreads to all the lobules of the prostate. The patient complains of signs of general intoxication of the body. Body temperature rises to 40 degrees. Urinary retention becomes acute. There are pulsating sensations in the perineum. Frequent constipation occurs.

Possible Complications

With untimely or poor-quality treatment, acute bacterial prostatitis can cause serious harm to the health and life of a man. The most dangerous of them is sepsis.

Also, the infection can rise above the prostate gland and lead to pyelonephritis or.

Bacterial prostatitis can turn into, the treatment of which is often difficult and leads to complications such as adenoma, infertility, impotence, etc.

Diagnostics

Since bacterial prostatitis has characteristic symptoms, it is usually fairly easy to diagnose. If the disease is not acute, the doctor will conduct a rectal examination, probing the area of ​​​​the gland and taking a sample of the secret for analysis. The following studies help to make a diagnosis:

1. Clinical and bacterial analysis of the patient's blood and urine.
2. Ultrasound of the prostate.

1. PSA blood.
2. Analysis of scrapings of the epithelium from the urethra.

Treatment

The danger of bacterial prostatitis is that it can quickly become chronic. That is why it is so important to start treatment when a disease is detected. After all, the chronic form of the disease contributes to the spread of the inflammatory process to the surrounding tissues and organs. If you ignore the treatment and do not take it, then the prostate can completely atrophy.

For the treatment of bacterial prostatitis are prescribed. Only a doctor can recommend this or that medicine after examination and obtaining the result of microbiological tests.

Treatment with antibacterial drugs is considered the most appropriate for the bacterial nature of the disease. Due to the fact that antibiotics are able to make the tissues of the organ permeable, the medicine can freely penetrate to the site of inflammation.

In the treatment of bacterial prostatitis, the following antibiotics are prescribed:

• Ampicillins ("Amoxiclav", "Augmentin", etc.).
• Macrolide preparations ("Azithromycin", "Clarithromycin", etc.) are quite effective in the fight against many pathogens.
• Medicines of the cephalosporin group ("Supraks", "Ceftriaxone", etc.) are effective in the acute phase of the disease.

• Fluoroquinolones ("Ofloxacin", "Ciprofloxacin", "Levofloxacin") are highly sensitive to many bacteria. Due to the fact that these medicines have a large number of side effects, they are prescribed with caution.
• Tetracyclines ("doxycycline") can be difficult to tolerate, so recently, they are prescribed very rarely.

The course of antibiotic treatment cannot be less than 10 days.

Additionally, non-steroidal anti-inflammatory drugs (Ibuprofen, Diclofenac) are used for treatment. They effectively relieve pain and inflammation of the prostate.

If problems with urination are observed, the patient is shown the use of alpha-blockers (Alfuzosin, Tamsulosin, etc.), which lead to a decrease in tension in the smooth muscles of the urethra and bladder.

Often, bacterial prostatitis is accompanied by a depressive state and a frequent change in the patient's mood. In such cases, the doctor recommends the use of drugs with a sedative effect (Afobazol, Miaser, etc.).

Urologist, andrologist Soloviev Nikolai Konstantinovich will talk about the use of antibiotic therapy:

If the disease is severe, the patient needs detoxification treatment, which consists in the intravenous administration of glucose, saline with trace elements and vitamin complexes. It is important for a man to observe the drinking regimen and drink at least 2 liters of pure water per day.

Medications should be aimed at normalizing blood circulation in the pelvic region and increasing the body's defenses. For this use:

1. Vitamin and mineral complexes.
2. Antispasmodics ("No-shpa", "Papazol", "Drotaverine", etc.).
3. Immunomodulators ("Imunofan").
4. Biological products ("Vitaprost").

In addition to taking medications, the doctor will recommend doing microclysters with a decoction of medicinal herbs (chamomile, calendula, etc.). The use of topical preparations in the case of bacterial prostatitis should be strictly limited, as there is a high risk of various complications.

After the elimination of the inflammatory process, the patient is prescribed treatment with physiotherapeutic methods (electrical stimulation of the prostate, magnetic therapy, etc.). They help speed up recovery and are performed on an outpatient basis.

In extreme cases, when medication has not given the desired result, the doctor may decide to perform a surgical operation. Such an intervention consists in resection of the prostate and is usually performed on older men. Young people are not prescribed such treatment due to possible complications (enuresis, impotence, infertility).

If bacterial prostatitis has become chronic, it is quite difficult to treat it. It must be remembered that it is no longer possible to do this at home.

Preventive measures

The best bacterial prostatitis is an active lifestyle. This is due to the fact that the gland itself is poorly provided with blood. Therefore, those who have a sedentary job need to regularly take a break in order to walk around a bit or do something (retracting the muscles of the anus, etc.).

A good effect gives a contrast shower. In this case, the jet of water is directed directly to the perineal area. The time of using warm (hot) water is 30 seconds, cool - should not exceed 15 seconds. The average duration of the procedure should be 5 minutes.

Preventive measures also include:

• Prevention of hypothermia of the body.
• Fight against constipation. If you can’t get rid of them on your own, you should consult a doctor who will advise mild laxatives.

• Normalization of sexual life (choosing a permanent partner, using a condom in case of doubtful contact, avoiding prolonged absence or excessively active sex).

• Regular preventive examination by a urologist for all men over 40-45 years old.

Forecast

What are the consequences of bacterial prostatitis in a man? The success of treatment depends on how timely and how well the therapy was prescribed. In addition, this is influenced by the patient's age, lifestyle, stage of the disease, the presence of other diseases of the body, etc.

The acute phase lends itself well to drug treatment, which, after a few days, significantly improves the condition of a man. But with improper treatment or its interruption, a relapse and the transition of prostatitis to a chronic form are possible, which is much more difficult to cure.

To avoid the unpleasant consequences of bacterial prostatitis, it is important for a man to monitor his health, follow preventive measures, and in case of discomfort in the perineum, consult a doctor.

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Antibiotics in the treatment of prostatitis are a medical course of treatment and they are prescribed in certain cases.

Often, it is precisely the right antibiotic therapy in the early stages of prostatitis that allows you to avoid the most undesirable consequences in the future.

When are antibiotics needed to treat prostatitis?

Prostatitis in men develops mainly under the influence of two main reasons. This is the penetration of various bacteria into the tissues of the organ and the violation of blood circulation in the pelvis.

Antibiotics for prostatitis are especially effective if the bacterial nature of the origin of the disease is proven.

Without antibiotic therapy, it is impossible to cope with the inflammatory reaction, which causes all the symptoms.

The course of antibiotics in each case is selected individually. The doctor also calculates the general treatment regimen.

Also, if the bacterial flora is not destroyed, it can negatively affect other organs, primarily the bladder and kidneys. That is, untreated prostatitis can also cause pyelonephritis, and later urolithiasis.

Antibiotics in the treatment of prostatitis are also necessary in the inflammatory process.

Often a sick man does not immediately go to the doctor. Many patients try and the acute phase of the disease fades on its own, but this does not lead to the complete elimination of the infection.

This means that in order to cope with bacteria, a course of antibiotic therapy must also be obtained in the chronic form of prostatitis.

Often, repeated antibiotic treatment regimens are prescribed in order to prevent another exacerbation of the disease.

What research is needed before prescribing antibiotics

Modern antibiotics for the most part have a wide spectrum of action, that is, they can destroy several types of bacteria simultaneously present in the human body.

But in order to successfully cure prostatitis, it is necessary to know which pathogens have influenced inflammation in the tissues of the prostate gland and whether they are sensitive to a certain group of drugs.

Acute prostatitis can be caused by both venereal disease pathogens, that is, chlamydia, gonococci, Trichomonas, and various streptococci and even E. coli.

Each type of these bacteria reacts in a certain way to the components of antibiotics and the task of the doctor is to find the optimal drug that will help to quickly destroy the pathogen and will not have a negative effect on the cells of the prostate gland.

Therefore, before prescribing an antibacterial treatment regimen, the patient must pass.

• To determine the causative agent of the disease, a prostate secret and a general urine test are needed;
• The degree of inflammation is determined by blood tests;
• Sensitivity to antibiotics shows bacteriological culture.

Based on the tests performed, the doctor selects the most effective drug. Depending on the stage of the inflammatory process and the patient's well-being, the antibiotic can be both in tablets and in injections.

The doctor also evaluates the ability of the components of the drug to penetrate into the tissues of the gland.

First of all, the drug is selected that quickly penetrates into the organ and lingers in it at the required concentration. Such treatment provides rapid elimination of inflammation and discomfort.

Injectables are usually stronger.

Rules for prescribing drugs

Antibiotics for prostatitis in the event that the patient turned to the urologist in the acute stage of inflammation are prescribed almost immediately. That is, the doctor will not wait for these tests.

Therefore, in the first days, a medicine with a wide spectrum of action is selected, the selection scheme is very similar in selection.

Preference is given to:

• macrolides.

• aminoglycosides.

• fluoroquinolones.

Antibiotics from the erythromycin group are prescribed less frequently, since they are not able to have a detrimental effect on several bacteria at once.

After laboratory data are received by the doctor, it usually takes two to three days, a decision is made either to continue the selected therapy regimen, or to prescribe a new, more effective drug.

When choosing a medicine, the doctor must take into account the age of the patient, the presence of certain somatic diseases in his anamnesis, and allergic reactions.

The patient, in turn, must warn the doctor about the antibiotics he has previously used.

If a man was treated with any medicine a few weeks before prostatitis, then it is likely that at this stage it will not be as effective as necessary to relieve inflammation.

Among the different groups of antibiotics there are so-called "reserves", they include drugs with a strong effect on the body. The urologist prescribes them only if the previous conservative treatment has not helped.

This may be evidenced by the lack of effect of therapy and the presence of the causative agent in repeated analyzes.

Strong antibiotics are mainly used in injections and therefore they are put into a vein or intramuscularly in a hospital setting.

For home treatment, antibiotics are selected in tablets, when using them, the doctor must tell in detail the entire treatment regimen.

Antibacterial therapy requires compliance with certain conditions.

• Antibiotics are prescribed for a certain period of time. Usually it is at least 2 weeks. In the future, the doctor evaluates the condition of the prostate gland and cancels the drug, or advises continuation of treatment;
• The dosage of the drug is also selected individually;
• The entire course of treatment must be completed. If it is interrupted, then the body develops suitable conditions for the transition of an acute infectious process into a chronic one;
• From the moment you start using antibiotics to reduce pain and discomfort, no more than three days should pass. If after this period the condition has not improved, then you need to re-consult a doctor for a review of therapy and the selection of another antibiotic.

Antibiotic therapy is one of the most important conditions for complete recovery from bacterial prostatitis. A sick man should understand that his trouble-free life in the future depends on compliance with the entire treatment regimen.

Groups of drugs for home treatment

Several decades have passed since the invention of antibiotics. And if at the beginning of their use the choice of groups of drugs was limited only to the penicillin series, then today there are several of them, and therefore it is not difficult for doctors to choose the most suitable one for their patient.

Antibiotics for prostatitis are selected from the following drug groups.

from penicillins.

This group has a wide range of effects on bacteria and therefore it is most often prescribed precisely before data is received from the laboratory.

Used in the treatment of prostatitis Amoxiclav, Amoxicillin. Another advantage of these medicines is their budgetary price, and therefore every patient can receive treatment.

from macrolides.

This group includes Sumamed, Josamycin, Klacid, Rulid. Macrolides perfectly penetrate the tissues of the prostate gland and begin to fight infection after their first intake.

This group of drugs is practically non-toxic and does not affect the state of the intestinal microflora.

Cephalosparins.

They are mainly used in hospitals, as they are administered intramuscularly or intravenously.

Tetracyclines.

Effective for prostatitis caused by chlamydia. But these drugs are highly toxic and have a spermatotoxic effect. Therefore, before planning the conception, they are not prescribed.

Fluoroquinols.

They are used when there is no effect from drugs of other groups. These drugs include Ciprofloxacin, Levofloxacin.

When using antibiotics for the first time, it is necessary to record all changes in well-being. These drugs often cause severe allergic reactions, especially in patients with a history of allergies.

Amoxiclav

The antibiotic Amoxiclav belongs to the penicillin group and has a wide spectrum of action.

Due to this, Amoxiclav is often prescribed in the acute period of prostatitis even before the tests.

This medicine is not prescribed for severe violations of the functioning of the liver and for sensitivity to penicillins. It is used with caution in patients with renal pathologies.

When treating with Amoxiclav, it is important to always follow the dosage, since a slight excess of the dose can affect the appearance of dyspeptic disorders, increase anxiety and cause insomnia.

Usually, uncomplicated prostatitis with Amoxiclav is cured in a few days.

Roxithromycin is a macrolide. The components of the drug penetrate into the tissues of the prostate gland and accumulate in them, due to this, the therapeutic effect occurs quite quickly.

Roxithromycin is rapidly excreted from the intestine, but it is not prescribed for severe liver disease.

During the course of treatment, the simultaneous use of ergot alkaloids is excluded. Macrolides effectively fight mycoplasma, chlamydia, gonococci.