Online consultations. Chlamydia, symptoms and treatment Tactics of chlamydia eradication

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Please respond to those who managed to cure chlamydia. Do such people exist in life?

06.11.2008 00:00, trash
I haven’t been treated for three years out of the five that I’ve been sick. Previously, I was treated using three systems from two different doctors. I didn’t keep the exact systems because a long time had passed and they didn’t help me, BUT I talked with SERGEY and wrote him the medications that I I took it because I don’t understand anything about them (and in general in medicine in general) and he told me that they were weak and not relevant. So I can only draw one conclusion that the way I was treated before was all *garbage*. Here I want to ask you Tanya, how are you feeling?

06.11.2008 00:00, Tanya

06.11.2008 00:00, Tanya
I started treatment with Klacid with Biseptol. It helped, but I don’t know whether it was Klacid or Biseptol. Probably Klacid because then I couldn’t take Biseptol because it was very bitter and I became one with Klacid, which was fine. I think you can eat 3 grams of Klacid at a time see how you feel.

06.11.2008 00:00, S
Does anyone know about Biseptol, they say that it can also treat chlamydia, has anyone tried using it in a regimen?

Treatment of chlamydia - drugs, treatment regimens for chlamydia

Today, the problem of treating chlamydia poses great difficulties for many doctors and patients, since often after treatment with antimicrobial agents, after a certain time, this insidious disease manifests itself again.

The problem is that most patients have chronic urogenital chlamydia, drug treatment for which is often ineffective.

What is the danger of chlamydia?

Chlamydia trachomatis most often causes the following pathologies of the urogenital tract:

  • urethritis in men and women (over half of all non-gonococcal urethritis),
  • prostatitis and orchiepididymitis in men, cervicitis, salpingitis, endometritis,
  • Combined organ damage is often observed (for example, urethritis, arthritis and conjunctivitis in the Reiter's syndrome program).

At the same time, there is a fairly extensive list of laboratory methods for diagnosing chlamydia, although the most reliable methods today are immunoassays with monoclonal antibodies (venous blood is used) and PCR diagnostics (usually scrapings of the endothelium of the urogenital tract).

In the treatment of chlamydial infection, as well as in the treatment of other infectious processes, the primary tasks are eradication of the pathogen and getting rid of acute or chronic inflammation of the genitals and urinary tract, which reduces the quality of life. Fortunately, a urologist, gynecologist or venereologist does not have a goal to reduce mortality from chlamydia, since dying from a chlamydial infection of the urogenital tract is very problematic.

An intermediate goal may be to avoid the chronicization of chlamydia, reduce the number of relapses of the chronic chlamydial process, as well as reduce the number of articular and ocular complications of urogenital chlamydia. We can also talk about the desire to reduce the number of complicated or miscarried pregnancies due to chlamydia and to avoid post-chlamydial infertility in both women and men.

Choice of drugs for the treatment of chlamydia

With an active inflammatory process, a whole range of medications is required for a full course of treatment for chlamydia. The drugs used in treatment regimens are selected by the doctor taking into account the individual characteristics of the patient’s body, clinical symptoms of the disease, the severity of the inflammatory process and the results of all tests - immunograms, liver tests, general blood tests, urine cultures, PCR results, ELISA and other laboratory data.

Today, treatment standards do not require the use of immunostimulants or immunomodulators in the treatment of even complicated chlamydia. Drugs of these groups, with the exception of serious cytostatic drugs that have strict indications and are prescribed only after an immunogram, should not be used as drugs with unproven effects. The shamanism of a large number of urologists, venereologists or gynecologists in this area is more often explained by bonuses from pharmaceutical representatives or an attempt to lengthen and increase the cost of treatment for patients of paid clinics and medical centers.

All information about medications and treatment regimens is intended for informational purposes only. Treatment of chlamydia is prescribed only by a qualified doctor based on test results, taking into account the patient’s medical history, concomitant diseases, etc.

Chlamydia eradication tactics

Eradication is essentially ridding the body of an infectious agent. Chlamydia is an intracellular resident, which, in addition to its main form, can exist in the L-variant (vegetative), which is not capable of exiting the cell and reproducing without significantly suppressing the host’s immunity, escaping from the effects of antibacterial agents or physical influences (increased temperature). The best way to treat chlamydia is with drugs from three antibacterial groups: tetracyclines, macrolides and fluoroquinolones.

It is worth noting that before starting therapy, sowing chlamydial cultures to determine sensitivity to antibiotics is not advisable, since studies conducted in 2000 at the Research Institute of Obstetrics and Gynecology named after. D.O. Otta RAMS, St. Petersburg, Research Institute of Physico-Chemical Medicine of the Russian Ministry of Health, Moscow, Institute of Clinical Bacteriology, Uppsala University, Sweden, showed that laboratory-resistant strains retained their sensitivity to antibiotics in patients.

Antibiotics for chlamydia

Antimicrobial agents are the main ones in the treatment regimen for chlamydia. And as a rule, for chronic chlamydia, drug treatment consists of using a combination of 2 antibiotics. The duration of the course of treatment and individual dosage are determined by the attending physician depending on the type of disease and the dynamics of the inflammatory process.

When choosing an antibiotic for chlamydia, laboratory data to determine the sensitivity of the pathogenic microorganism to a specific antibacterial drug is indispensable. Therefore, it is advisable to supplement cultural methods of laboratory diagnostics with an antibiogram.

Treatment of chlamydia in men: symptoms, treatment regimens, effective drugs

This type of microorganism cannot synthesize energy on its own; they are completely dependent on the host cell. It is this feature of chlamydia that determines the main route of transmission of infection - sexual (in rare cases - hematogenous, contact-household).

The prevalence of chlamydia in men is up to 4%, while up to 30% of urethritis is associated with chlamydial infection. However, only people with severe symptoms seek medical help, which leads to an increase in the number of sick and infected people.

Causes of the disease

The causes of chlamydia infection can be:

  1. Absence of barrier methods during sexual intercourse with an “unverified partner.”
  2. Decreased protective reserves of the body (in immunodeficiency states).
  3. Latent course of the disease (without clinical signs) in a partner.

Clinical symptoms

Signs of chlamydia in men can be tracked by certain symptoms.

The disease is characterized by:

  1. Itching in the urethra.
  2. Burning, pain when urinating (urine may be cloudy).
  3. Light, almost colorless discharge from the urethra.
  4. Frequent urge to urinate.
  5. Redness and slight swelling in the area of ​​the urethral outlet.
  6. Swelling, sharp pain, local increase in temperature in the scrotum area.
  7. Pain in the scrotum, rectum.
  8. Pain in the lumbar and sacral regions, and even in the lower extremities (along the sciatic nerve).
  9. Possible Reiter's triad: urethritis, conjunctivitis and arthritis. As a rule, one of the large joints (for example, knee, hip or ankle) is affected unilaterally.
  10. Discomfort during defecation (typical for damage to the rectum and prostate).

Early treatment

To effectively treat chlamydia in men, it is necessary to act on the causative agent of the disease.

In the primary acute process, antibacterial drugs from the group of macrolides (Azithromycin, Clarithromycin, Josamycin, Midekamycin) and tetracyclines (Doxycycline) showed good results.

However, treatment with drugs from a number of tetracycline antibiotics has a number of disadvantages:

  1. A course of treatment for 1 week does not achieve the desired result. According to studies, relapse of the disease occurs in 15-20% of cases with this treatment regimen.
  2. Extending the time of taking medications to 14 days is dangerous due to the re-development of infection in 15% of cases.
  3. Treatment for 21 days avoids relapses, as it affects 7 cycles of development of the infectious agent. However, such a long-term regimen is inconvenient for patients: violations in taking antibiotics often occur. Skipping pills or not using them regularly can lead to the development of chlamydia resistance to this drug. In addition, long-term use of drugs can provoke the development of fungal infections, as well as dysbiosis of the digestive tract. To prevent these complications, it is necessary to prescribe antifungal drugs (Nystatin, Levorin, Ketoconazole), as well as eubiotics (Linex).

Considering the above disadvantages of antibiotics from the tetracycline group, the most convenient is treatment with macrolides.

The drug Azithromycin (Sumamed) is especially effective.

Advantages of the drug "Azithromycin" :

  1. A convenient treatment regimen is a single dose of 1 g of Azithromycin.
  2. The effect of the drug lasts 10 days even after a single dose (this effect is created due to the half-life).
  3. A simple scheme ensures 100% compliance with the doctor’s recommendations.
  4. Azithromycin persists for a long time in tissues affected by the inflammatory process.
  5. Low percentage of side effects.
  6. The antibiotic affects intracellular pathogens due to the ability to accumulate inside cells (in particular, phagocytes). This is very important in the treatment of chlamydia, since chlamydia is completely dependent on the host cell.

So, if you carefully choose a drug and are thinking about how to more effectively cure chlamydia in a man, the best drug is Azithromycin (Sumamed), an antibiotic that fully meets the requirements for the treatment of chlamydia.

Treatment of chronic chlamydia

The chronic form of the disease is much more difficult to effectively treat and is dangerous due to the occurrence of relapses.

Preference is also given to antibiotics from the group of tetracyclines and macrolides.

The following treatment regimens are effective:

  1. Continuous intake of Doxycycline 200 mg 2 times a day for 28 days.
  2. The pulse therapy method consists of prescribing tetracyclines 3 times for 10 days with a break of 7 days. This scheme makes it possible to influence resistant intracellular strains of bacteria, affecting all development cycles.
  3. Take Azithromycin 500 mg 2 times a day for 5 days (or 7 days for a long, often relapsing course of the disease).

Be sure to prescribe, along with the use of etiotropic treatment:

  1. Eubiotics (“Linex”, “Bifiform”)
  2. Anticandidal drugs (Nystatin, Fluconazole).
  3. Immunomodulators (“Polyoxdonium”, “Interferon-Alpha”).

Consequences of chlamydial infection for men

In addition to pain in the affected organs and tissues, there are also long-term consequences:

  1. Chlamydial infection is the cause of male infertility in 30%.
  2. With a long course of the disease without proper treatment, the formation of chronic pelvic pain syndrome is possible.
  3. Chlamydia can cause erectile dysfunction (if the infection spreads to the prostate).

Chlamydial infection is very “insidious”, since in most cases it is practically asymptomatic or “masked” in the form of banal cystitis and urethritis. However, the consequences of this disease can be extremely serious.

Lack of timely treatment for chlamydia can cause irreversible changes in reproductive function (infertility development). For this reason, it is necessary to follow the principles of “protected” sexual intercourse, and if alarming symptoms occur, be sure to consult a doctor to prescribe competent and effective treatment.

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Chlamydia, symptoms and treatment.

Chlamydia is an infectious disease that is sexually transmitted and mainly affects the genitourinary system. The causative agent is Chlamydia trachomatis, an intracellular microorganism.

Every year, about 80 million new cases of chlamydia infection are registered worldwide.

Chlamydia infection routes:

  1. Sexual (main route)
  2. Household (rarely)
  3. During pregnancy - intrapartum/intrauterine.

Risk groups for the disease:

  1. young age and early sexual life
  2. a large number of sexual partners + casual relationships.
  3. uncontrolled use of antibiotics and hormonal drugs.
  4. gynecological diseases.
  5. frequent abortions

Chlamydia symptoms:

Symptoms of chlamydia in women are somewhat different from those in men.

  • The incubation period for chlamydia lasts on average 7–14 days, it is shorter than for gonorrhea. The course is usually asymptomatic (especially in women).
  • scanty discharge from the urethra and vagina, mucous or mucopurulent, can be in the form of a morning drop (in men).
  • itching, pain, discomfort in the urethra.
  • increased frequency of the urge to urinate.
  • Discharge from the urethra often appears after prolonged urinary retention, during bowel movements or at the end of urination.
  • inflammation of the urethral sponges, their redness and sticking together.

You can find out more about the symptoms of chlamydia in the following articles:

Chlamydia treatment.

Treat the necessary treatment for both the patient and the sexual partner!

Treatment for chlamydia includes:

  1. Etiotropic (effects on chlamydia)
  2. Pathogenetic
  3. Symptomatic
  4. Local methods of treatment.

Etiotropic treatment of chlamydia:

Tetracyclines have the greatest effect, especially semisynthetic tetracyclines - doxycycline and other drugs of this group (Unidox Solutab, Vibramycin, Minocin, etc.). For uncomplicated chlamydia:

Prescribe doxycycline 200-300 mg/day (in 2 doses) or tetracycline (2.0-2.5 g/day, 4 doses) for 10-14-21 days. It has been noted that intravenous administration of doxycycline is more effective and better tolerated by patients.

If the use of tetracyclines is contraindicated (pregnant women, nursing mothers, newborns, children under 7 years of age), macrolides are recommended:

Erythromycin (2.5-2.0 g/day, 4 doses, 14-15 days, considered as a reserve antibiotic) and other drugs of this group (macropen, rovamycin, Rulid, etc.);

Azalides - azithromycin (sumamed, zithromax, etc.) - 1.0 g orally (in 1-2 doses).

Fluoroquinolones are recommended for the treatment of chlamydia - ofloxacin (600-800-1200 mg/day, 2-3-4 doses), ciprofloxacin (1,000-1,500 mg/day, 2-3 doses), etc. The drugs are good when taken orally absorbed, also prescribed intravenously (drip); Not recommended for pregnant women, children and adolescents, as well as persons with mental disorders. In many cases, sulfonamides are effective, incl. their combined forms (especially when combined sequentially with tetracyclines or erythromycin) - Bactrim, Biseptol, etc.

Pathogenetic treatment:

In complicated forms of the disease (along with etiotropic drugs), the use of pathogenetic therapy is mandatory. Interferon inducers (cycloferon, neovir, amiksin, savrac, kagocel, etc.), natural and recombined interferons (laferon, etc.), thymus preparations, systemic polyenzymes, and, if indicated, sex hormones should be prescribed; biocorrection with eubiotics, etc. They use methyluracil, sodium nucleinate, levamisole, aloe extract and other means of nonspecific immunotherapy, as well as biogenic stimulants, adaptogens, therapeutic doses of vitamins.

Local treatment:

carried out taking into account the location of the lesion. On the other hand, there are objections, for example, to the introduction of antiseptics into the urethra (irritant effect, including burns of the mucous membrane, epithelial metaplasia, formation of strictures).

As local effects, rinsing, douching with a solution of potassium permanganate (1:8000) is used in alternation with instillations of solutions: 1-2% protargol, collargol, 0.25% copper or zinc sulfate, as well as the use of formulations with erythromycin, tetracycline, nitroxaline , quinozole, metronidazole, oil solution of chlorophyllipt, levorin - with the addition of dimexide (no more than 10-20%).

Of the official drugs, you can use the appropriate suppositories, creams, ointments (tetracycline, erythromycin, betadine, vocadine, iodicerin, etc.) - in the form of applications, vaginal tampons. It is advisable to use probiotics locally (on days free from local drugs) - tampons with liquid bifidum-bacterin or lactobacterin, etc. Clinical cure should be confirmed laboratory (PCR, level of chlamydial antibodies, their decrease, etc.).

Attention! Do not self-medicate. Treatment should be prescribed by your attending physician, after a thorough examination and a number of laboratory and instrumental research methods. The dosage, course of administration and groups of drugs are selected individually! Clinical cure of chlamydia should be confirmed laboratory (PCR, level of chlamydial antibodies, their decrease, etc.).

Prostatitis is a disease of the prostate in which inflammation occurs. Most often, the cause of pathology is infection of the gland by pathogenic microbes, mainly Escherichia coli, staphylococci, streptococci, and less often other microorganisms and STIs.

Prostatitis is also caused by congestion in the gland; this is usually observed in elderly patients. Men in the midst of their reproductive years suffer precisely from bacterial prostatitis, which requires treatment. Biseptol is an antibiotic that is used to treat prostatitis. But before starting therapy, you should read the instructions and consult your doctor.

The benefits of Biseptol for prostatitis

Biseptol is a rather outdated drug that is currently not prescribed so often. Andrologists, especially young ones, prefer more modern drugs that have fewer side effects, but are very effective for bacterial prostatitis.

You need to understand that there are no bad antibiotics, only the wrong course of treatment. Therefore, the use of Biseptol for prostatitis is not excluded, but it is very important to first determine whether the bacteria that provoked the inflammation are sensitive to this remedy.

Biseptol is a drug from the sulphyllamide group. Sulfamethoxazole, which is part of the drug, is very similar in composition to para-aminobenzoic acid. This is a vitamin-like component involved in the synthesis of folic acid in microbes; it is an important factor in the growth of bacteria. The drug replaces para-aminobenzoic acid and thus disrupts the process of growth and division of pathogenic microorganisms, which leads to their death.

Many microorganisms are sensitive to the drug, including those that provoke prostatitis:

  • steptococci;
  • coli;
  • staphylococci;
  • salmonella;
  • Klebsiella, etc.

Biseptol is also effective against chlamydia and gonorrhea. But with genital herpes and candidiasis, this drug will not help. Therefore, before starting treatment, you need to consult a doctor to identify the type of pathogen.

Do not forget that prostatitis still requires complex therapy. Despite the positive reviews about Biseptol, it is most likely impossible to get by with just one drug. The patient must also take other medications prescribed by the doctor, for example, vitamins. It is also very important during the period of treatment of acute bacterial prostatitis to rest more, maintain sexual rest, and eat a balanced diet.

When taking Biseptol during pregnancy, you must not forget about regular sex and the prevention of genitourinary infections.

Contraindications and side effects

Biseptol is used in the treatment of a variety of diseases, the list of indications includes pathologies of the respiratory tract, pelvic organs, skin and intestinal infections and other bacterial infections such as scarlet fever, toxoplasmosis, etc.

The drug is widely used for prostatitis, urethritis, pyelonephritis, as well as for sexually transmitted diseases of a bacterial nature. The advantage of the drug is the slow development of resistance to it, which many modern drugs cannot boast of.

The following situations are contraindications to taking Biseptol for prostatitis:

  • If the disease was provoked not by bacteria, but by fungi or viruses, protozoa.
  • For serious kidney pathologies.
  • Pathologies of the cardiovascular system are also contraindications.
  • Hypersensitivity to the components of the drug, in particular to antibiotics of the sulfonamide group.

For pathologies of the endocrine system, bronchial asthma and atopic dermatitis, before using the drug, you need to consult an appropriate specialist. This is associated with an increased likelihood of side effects.

Side effects of Biseptol in the treatment of prostatitis:

  • disorders of the gastrointestinal tract;
  • allergic skin rashes;
  • headaches, depression;
  • changes in the synthesis of B vitamins.

Biseptol is usually easily tolerated and no serious side effects occur. If you do experience a rash or other symptoms, it is best to consult your doctor.

How to take Biseptol for prostatitis

How to take Biseptol for prostatitis, it is better to ask your doctor. Any antibiotic will be ineffective if the dosage is chosen incorrectly. Only a doctor can recommend the right course of therapy.

When treating prostatitis with Biseptol, it is very important to take the drug as much as the doctor tells you. Even if the pain has long disappeared and urination has returned to normal, you cannot stop taking the medicine ahead of time. This will lead to the fact that not all bacteria will die, and a relapse will soon occur, as soon as you become hypothermic.

Most often, Biseptol for prostatitis is prescribed in a dosage of 480 mg twice a day, that is, the patient must take 960 mg of the drug per day. The duration of therapy is at least 14 days, usually even longer.

In any case, this issue needs to be discussed with a doctor; only an andrologist can assess the severity of the situation and say how long the drug should be used.

Biseptol is recommended to be taken in the morning and evening after meals, with plenty of water. Alcohol is contraindicated during treatment, as it can enhance the negative reactions of the drug. In addition, the drug has some negative effects on the liver, which increases when taking ethyl alcohol. And the symptoms of prostatitis become more pronounced when drinking alcohol.

Many patients are interested in reviews of the use of Biseptol for prostatitis. This drug is very popular among men because it is very effective for inflammation of the prostate gland. But despite the fact that patients praise Biseptol and the reviews about it are mostly positive, it is not recommended to prescribe it for yourself for prostatitis.

Treatment of inflammation of the prostate gland with Biseptol must be selected in consultation with a doctor. If the patient is sure that the drug will help him, it is better to discuss this with his andrologist rather than risk his health. If Biseptol really helps in a particular case, the doctor will allow you to take it and tell you how to do it correctly.

Conclusion

Prostatitis is the most common male disease, which greatly impairs the quality of life, leading to impotence and urinary incontinence. Therefore, patients are advised to consult a doctor at the first signs of the disease and be treated under his supervision.

ANSWERED: 02/22/2012

Hello, Sergey! Previously, this drug was used to treat chlamydia. Currently, it is not used due to its low effectiveness.

Clarification question

ANSWERED: 02/27/2012 Maystryonok Anna Mikhailovna Baranovichi 0.0 dermatovenerologist

Dear Sergey! In any case, before taking antibiotics that your doctor will prescribe for you (taking into account allergies), you need to do a test to determine their tolerance (for example, RAL). For the treatment of chlamydia at the farm. There are enough drugs of different groups on the market.

Clarification question

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Urogenital chlamydia is one of the most common infectious and inflammatory diseases. According to estimates, the number of newly diagnosed cases is about 4 million per year. It affects almost half of men of active sexual age (from 16 to 40 years old) and a third of women.

The causative agent of chlamydia

The disease is caused by bacteria of the chlamydia genus. In nature, there are 4 types of chlamydia. Chlamydia trachomatis and Chlamydia pneumoniae are predominantly human pathogens, while the other two primarily infect animals. In terms of their properties, chlamydia occupy an intermediate position between viruses and bacteria. Therefore, chlamydia is still more difficult to diagnose and treat than ordinary bacterial infections. Urogenital chlamydia is a sexually transmitted disease. There is often a combination of chlamydia with other genitourinary infections - trichomoniasis, gardnerellosis, ureaplasmosis.

Symptoms of chlamydia

The incubation period for chlamydia is approximately 1-3 weeks. Women experience slight discharge from the cervical canal, and may also experience itching, pain when urinating, and bleeding during the intermenstrual period. Sometimes the general condition suffers - weakness is noted, body temperature rises slightly. It should be noted that chlamydia often occurs without pronounced symptoms or does not manifest itself at all. Even without treatment, after some time (about 2 weeks), the symptoms of the disease disappear. In this case, chlamydia becomes chronic; the chlamydial infection is, as it were, “preserved” in the body, waiting for an opportunity to remind itself again.

Complications of chlamydia

The main danger of chlamydia lies precisely in the complications it can cause. In women, chlamydial infection often causes obstruction of the fallopian tubes, ectopic pregnancy, postpartum or post-abortion endometritis. Chlamydia can get on the wall of the bladder and cause hemorrhagic cystitis. Chronic inflammation of the urethra caused by chlamydia leads to the development of its narrowing (stricture). In addition to various complications affecting the genital organs, chlamydia can cause damage to other organs. Then this disease will already be called disease, or Reiter's syndrome. With Reiter's syndrome, the eyes (chlamydial conjunctivitis), joints (usually ankles, knees and spine), skin, and internal organs (usually hepatitis, but almost any organs can be affected) can be affected.
Chlamydia is especially dangerous in pregnant women. During pregnancy, an asymptomatic course of chlamydia is typical. At the same time, the course of pregnancy is characterized by a high frequency of complications. The threat of miscarriage is observed in every second woman with chlamydia. The incidence of ectopic pregnancy, spontaneous abortion, and undeveloped pregnancy is also high. When chlamydia affects the tubes and endometrium of the uterus, the process of development of the placenta is disrupted, which leads to disruption of the proper maturation of the fetus, improper formation of organs in the early stages of pregnancy, or low birth weight of the fetus when infected with chlamydia in late pregnancy.

Diagnosis of chlamydia

Diagnosing chlamydia is more difficult than diagnosing a bacterial infection. The simplest methods have an accuracy of no more than 40%. The most accurate and accessible method for determining chlamydia today is the immunofluorescence reaction (RIF) using antibodies labeled with a special substance - FITC.
It is safe to say about chlamydia that it is much easier to avoid than to cure. Prevention of complications of chlamydial infections attracts special attention, since patients with asymptomatic disease do not seek medical help. An example of successful experience in the prevention of chlamydia is Switzerland, the only country in the world where the number of patients with chlamydia is declining. Prevention of chlamydia in the country consists of the following main provisions: creation of a network of diagnostic laboratories, free treatment, promotion of the use of condoms, increasing the moral responsibility of partners for the spread of chlamydia infection.

Treatment of chlamydia

Due to the characteristics of chlamydia, antibacterial drugs against them are not as effective as against ordinary bacteria, therefore the treatment of chlamydia is more complex and time-consuming. In addition to the course of antibacterial therapy, it necessarily includes immunomodulatory therapy, multivitamin therapy, diet, and abstinence from sexual activity for the duration of treatment. Treatment of chlamydia must be carried out for all partners. At the end of the course, control tests are carried out. If chlamydia is not detected, then tests are carried out 2 more times after 1 month (in women - before menstruation). Only after this will it be possible to talk about the effectiveness of the therapy.
The following groups of antibacterial drugs are used to treat chlamydia:
1. Group of tetracyclines (Unidox salutab, Bassado, Vibramycin, Doxylan, Doxycycline Nycomed, Doxycycline hydrochloride, Doxt, Medomntsin, Tetradox, Metacycline hydrochloride, Tetracycline hydrochloride, etc.).

Drug for the treatment of chlamydia: Unidox solutab (Yamanouchi Europe, Netherlands)

Oral form of doxycycline. After oral administration, doxycycline is almost completely absorbed from the gastrointestinal tract. Eating food or milk has little effect on the absorption of doxycycline. Doxycycline reversibly binds to plasma proteins (80-90%) and penetrates well into tissues. Accumulates in the reticuloendothelial system and bone tissue. The recommended dosage is 0.1 g (1 tablet) x 2 times a day. The half-life of Unidox Solutab after a single oral dose is 16-18 hours, after taking repeated doses - 22-23 hours. The half-life of doxycycline in patients with impaired renal function does not change, because its excretion through the intestines increases. Hemodialysis and peritoneal dialysis do not affect the concentration of doxycycline in the blood plasma.
1 soluble tablet of Unidox Solutab contains 100 mg of doxycycline monohydrate.

2. Group of co-trimoxazoles (Co-trimoxazole, Aposulftrim, Bactoreduct, Bactrim, Bactrim syrup, Berlocid 240,480,960, Bicotrim, Biseptol, Bisutrim, Groseptol, Duo-septol, Intrim, Co-trimoxazole-ICN, Co-trimoxazole-ACRI, Co -trimoxazole-TEVA, Cotrimol, Cotripharm 480, Oriprim, Rancotrim, Septrin, Septrin-forte, Sinersul, Sulotrim, Sumetrolim, Trim, Trimezol, Trimosul, Tsiplin, Expozol and others).
Co-trimoxazole - active substances - sulfamethoxazole and trimethoprim. It has a bactericidal effect against a number of gram-positive and gram-negative microorganisms, including chlamydia. The dosage regimen is set individually and depends on the type of pathogen, the severity of the infection, and the dynamics of the patient’s condition.

Drug for the treatment of chlamydia: Biseptol (Polfa, Poland)

Antibacterial agent with a wide spectrum of action. The combination of trimethoplrim and sulfamethoxazole enhances the bacteriostatic effect. Biseptol has a stronger effect on bacteria and less often leads to the formation of resistant strains than its components used in monotherapy. The drug is quickly and completely absorbed from the gastrointestinal tract. The drug should be taken with plenty of liquid, preferably after a meal. Biseptol is usually well tolerated by patients. Sometimes there are dysfunctions of the digestive tract (nausea, vomiting, less often diarrhea) and allergic skin reactions. Available in the form of tablets of 120 and 480 mg.

3. Group of macrolides - azithromycin (Sumamed, Azivok), clarithromycin (Klacid, Kriksan, Klabaks, Fromilid), erythromycin (Erythromycin), midecamycin (Macropen), roxithromycin (Rulid), spiramycin (Rovamycin), josamycin (Vilprafen) and others.

Drug for the treatment of chlamydia: Wilprafen (Heinrich Mack Nacht, Germany)

An antibiotic whose active ingredient is josamycin. When high concentrations are created at the site of inflammation, it has a bactericidal effect. After oral administration, the drug is quickly absorbed from the gastrointestinal tract. Taking the drug at intervals of 12 hours ensures that a high concentration of the active substance is maintained in tissues throughout the day. Indicated for the treatment of infectious diseases of the genitourinary system, including genital chlamydia. As a result of the studies, Vilprafen proved to be a fairly effective remedy for the treatment of urogenital chlamydia (of 68 patients observed, cure was achieved in 64 (94.1%)). Compared to other macrolides (for example, erythromycin), Vilprafen has a more favorable safety profile; it causes fewer side effects from the gastrointestinal tract. The drug is available in the form of film-coated tablets, 500 mg, 10 pcs. in packaging, and oral suspensions of 300 mg (in 10 ml), 100 ml in a bottle complete with a measuring cup.

4. Group of fluoroquinolones (Maxaquin, Ofloxin 200, Abaktal, Normax, Okatsin, Tsifran, Tsipromed, Tsiprlet, Ciloxan, Peflacine, Peflacin, Perflox, Perti, Tarivid, Zanotsin, Normax, Norilet, Girablok, Norbactin, Nolitsin, Lomflox, Raksar, Enoxor, Tsiprinol, Quintor, Quipro, Liprokhin, Tsiprobay, Tsiprosan, Ciprofloxacin, Tsifloksinal, Tsiprocinal and others).

Drug for the treatment of chlamydia: Abaktal (Lek, Slovenia)

A synthetic broad-spectrum antimicrobial agent whose active substance is pefloxacin. Abactal is rapidly absorbed (20 minutes after oral administration of a single dose of 400 mg, 90% of pefloxacin is absorbed) and reaches maximum concentration 1-2 hours after administration. Thanks to its high volume of distribution, it quickly penetrates into tissues, organs and body fluids. The drug is indicated for the treatment of infections caused by organisms sensitive to pefloxacin: urogenital infections, including chlamydia. During treatment with Abaktal, exposure to ultraviolet radiation should be avoided. Available in the form of 400 mg tablets and solution for injection.

Drug for the treatment of chlamydia: Girablok (Medochemie, Cyprus)

The drug, the active ingredient of which is norfloxacin, is an antibiotic from the fluoroquinolone group. Causes a decrease in the virulence of microorganisms, suppression of their production of exotoxins and exoenzymes, and an increase in phagocytic activity against microbial cells. When taking Girablok, high concentrations are created in the intestines, bile, prostate gland, testicles, uterus, kidneys, bladder, urethra; effective when taken orally. It has a wide spectrum of bactericidal action, is active against extra- and intracellular pathogens, including chlamydia and mycoplasmas. Girablok is also active against hospital strains, including Pseudomonas aeruginosa. Causes a long-term post-antibiotic effect. The development of bacterial resistance to the drug is very slow, “multi-stage”. Indications for use are infections of the urinary system; genital organs, including prostatitis, cervicitis, gonorrhea; acute bacterial enterocolitis. It is several times more active against urinary infections than nalidixic acid. The frequency of side effects when using the drug does not exceed 5%. Release form: film-coated tablets, 200 and 400 mg.

Drug for the treatment of chlamydia: Maxaquin (Searle, USA)

A broad-spectrum antimicrobial drug whose active ingredient is lomefloxacin. Resistance to Maxaquin rarely develops. The drug is active against strains of microorganisms that are multi-resistant to antibiotics. The drug is indicated for the treatment of acute and recurrent chlamydia (including mixed bacterial-chlamydial infection). Maxaquin is used 400 mg once a day, regardless of food intake. The duration of treatment for acute chlamydia is 14 days, for recurrent chlamydia, including mixed bacterial-chlamydial infection, 14-21 days. Maxaquin is produced in the form of film-coated tablets containing 400 mg of active substance, 5 pieces in a blister.

Drug for the treatment of chlamydia: Sparflo (Dr. Reddy's Laboratories, India)

A new antibacterial drug from the fluoroquinolone group. The main active ingredient of the drug is sparfloxacin, which has the highest activity against gram-positive bacteria without significant changes in activity against gram-negative microbes, compared to other widely used fluoroquinolones. Sparflo is relatively slowly absorbed from the gastrointestinal tract and penetrates well into various organs and tissues of the body. It is characterized by a prolonged action and provides a high concentration in the tissues and cells of the phagocytic system. The drug can be taken regardless of meals. Indications for the use of Sparflo are infections of the respiratory tract, kidneys and urinary tract, skin and soft tissues, gastrointestinal tract, surgical infections, as well as sexually transmitted diseases - gonorrhea, chlamydia. It is the drug of choice for the treatment of nosocomial infections. The drug is easy to use - it is active in low daily doses when taken orally, applied once a day. The drug is usually well tolerated. During treatment with Sparflo and for 3 days after the end of treatment, patients should not be exposed to ultraviolet radiation due to the possibility of developing photosensitivity reactions. Available in the form of film-coated tablets containing 200 mg of sparfloxacin, 6 tablets per package.

Drug for the treatment of chlamydia: Tsiprolet (Dr. Reddy's Laboratories, India)

A powerful and fast-acting antibacterial agent, the active substance of the drug is ciprofloxacin. From the group of fluoroquinolones. It acts bactericidal, inhibiting DNA gyrase of bacteria, without exerting a toxic effect on human cells due to the difference in enzyme systems. Effective against most aerobic gram-negative and gram-positive microorganisms. The drug acts on strains resistant to other antibacterial agents. Tsiprolet has a large volume of distribution in the body and creates high concentrations in tissues. It is used for various infections caused by microorganisms sensitive to the drug, in particular for infections of the respiratory system, ENT organs, genitourinary system, gastrointestinal tract, bones and joints, skin and soft tissues, sepsis, as well as gonorrhea. The use of the drug is contraindicated during pregnancy and lactation, as well as in childhood until the end of intensive growth. Tsiprolet is available in the form of tablets of 250 or 500 mg, 10 tablets per package, a solution for injection in bottles of 200 mg 100 ml and an ophthalmic solution in a dropper bottle (3 mg/5 ml).

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