Anthelmintic drugs for people with a wide spectrum of action. Deworming. Instructions for the use of anthelmintic drugs Foresta and anthelmintic drugs can be taken together

Deworming: Frequently Asked Questions.

What is deworming?

At what age and how often should an animal be dewormed? In what case is repeated deworming needed 10 days after the main one?

Periodic deworming is best started at 3 weeks of age. For this purpose, use preparations marked “For kittens” and “For puppies”. The rest of the angelmints are designed for more mature individuals - such products are best used no earlier than 1.5 months, or even 2 months of age.

The frequency of preventive deworming varies depending on age. It is recommended to deworm young pets up to one year old at least once a quarter (3 months). It is customary to deworm adult animals once every six months.

What types of angelmints are there?

For preventive deworming, you choose the type of drug that is suitable for your animal’s age, as well as the most convenient to use and calculate the dose.

For example, now the vast majority of anthelmintic tablets for dogs are designed for 10 kg of animal weight. But how many microscopic parts will the tablet have to be divided into if you have a Chihuahua weighing 950 grams? In such a case, it is more convenient to use suspensions for small breeds of dogs - they come in a dosage of 1 ml per 1 kg of weight. Or even use drops on the withers (spot-ons). Simple arithmetic!

Now there are various dosage forms of angelmintics on the market: tablets, suspensions, drops on the withers. You choose the drug that will be easier/more convenient to set. If in doubt, consult a pharmacist at your local veterinary pharmacy.

Isn't this dangerous?

It should be noted that anthelmintic drugs are poison in a prophylactic dose. This means that their active ingredients (praziquantel, fenbendazole, albendazole, piperazine, ivermectin, pyrantel, etc.) in doses specified by the manufacturer are safe for the health of the pet.

Two basic safety rules for the deworming procedure:

My animal does not leave the house, should it be dewormed?

Necessarily. If a pet does not go outside, this does not mean that it cannot be infected. Animals that do not leave the apartment are dewormed according to the general scheme: up to a year - once every three months; after a year - once every six months.

If your animal does not go for walks, but eats raw meat, offal, minced meat, and fresh fish, it should be dewormed once every 3-4 months.

Why do veterinarians insist on deworming the animal before vaccination?

We veterinarians often hear:

“We have a “clean” animal, we don’t go for walks anywhere, we have no need to worm!” or

“We would have noticed his discomfort!”

Dear owners:

Just like in order to contract a viral infection, an animal does not necessarily need to go for a walk. Most of your pets are infected in early childhood, from a mother who was not wormed before mating; It is also important to remember that YOU walk down the street - and bring all sorts of things on your shoes. There is also a risk of infestation from raw meat if you feed your pet natural food.

Understand, the term “preventive deworming” would not exist if it were not necessary.

It is necessary to deworm the animal 7 - 10 days before vaccination to achieve the best effect of vaccination and the formation of strong, lasting immunity.

Is it possible to give angelmints to pregnant and lactating animals?

The annotation for most drugs states that it is not recommended to anthelmintize lactating and pregnant females. And this is true, because the drug, being absorbed into the blood, enters the fetus, having an embryotoxic effect, or ends up in the milk that the cubs feed on. The result is developmental disorders or severe poisoning.

To protect the expectant mother and her offspring, it is recommended to deworm the female 10-14 days before the intended mating; subsequently, the cubs are wormed 3 weeks after birth.

However, manufacturers of some drugs allow deworming of pregnant and lactating animals; but many veterinarians are skeptical of such claims and stick to the old scheme.

But there are critical situations: for example, you picked up a pregnant cat, and then realized that she had worms. What to do? Take emergency measures. If there is no choice, you can trust drugs whose annotations indicate their harmlessness to the fetus; Or you can wait until the birth, and immediately after it, worm the animal, neither earlier nor later. There is an option to combine these two methods. But in any case, this is done after carefully weighing all possible consequences!

CONCLUSION:

1) preventive deworming is an integral part in the process of maintaining the health of your pet;

2) kittens and puppies are dewormed no earlier than 3 weeks of age once every 3 months; Upon reaching the age of one year, young animals that do not go outside and consume ready-made food are dewormed once every six months. It is recommended to deworm street animals every 3-4 months.

3) deworming of animals is mandatory 7-10 days before the expected date of vaccination;

4) deworming of pregnant and lactating animals is prohibited to avoid toxic active substances entering the fragile body of the fetus;

5) choosing the form of anthelmintic is not a fundamental question, boiling down to what exactly will be easier to ask the animal.

6) Two basic safety rules for the deworming procedure:

  • Strictly act in accordance with the instructions for the drug: follow the dosage, regimen, frequency.
  • Do not deworm weak, sick, exhausted, or recently operated animals. In this case, the pet’s body is weakened, and the additional toxic effects of angelmintics can lead to disastrous results.

7) Be sure to deworm the animal 7 - 10 days before the intended vaccination; this helps to achieve a better vaccination effect and the formation of a healthy, viable immune system.

8) Deworming of lactating and pregnant females is not recommended. Deworming should be carried out 10-14 days before the intended mating. Cubs are dewormed no earlier than 3 weeks of age.

Now, let's talk about antihelminthics.

Indeed, as you write, most first-time residents are well aware of 3-4 medications for worms and, most often, this is enough.

But I remember one incident from my pharmacy life. Once a buyer came to us, named some exotic rubbish and asked us to find him a medicine for it.

We ourselves began to wonder if we had a remedy that could cope with it?

We reached into the storage unit, were surprised that it turned out that there were not 3 anthelmintic drugs, but more, we began to get instructions and read the complex Latin names of helminth infections in order to find this exotic one.

Of course, now we can say that a doctor should prescribe this, blah blah blah, but, you know how it happens... I really wanted to help the person.

Our search was crowned with success, the drug was found! We felt like winners!

Below I will talk about it.

So today we will talk about those drugs that are well known to you, and those, or rather, the one that is not at all well-known.

How do they work?

Which illegal immigrants are affected?

What antihelminthic drugs are prescribed for very young children, and which ones can be taken by pregnant women?

And what should you tell the buyer when selling each product?

I took information about the drugs from the website of the State Register of Medicines.

I will not touch on “dead souls” that are no longer on the market: fenasal, medamin, niclosamide, chloroxyl, etc.

Well, shall we get started?

Levamisole (Decaris)

Available in two forms: tablets of 150 mg, 1 piece per package, and 50 mg tablets, 2 pieces per package.

Remember:

Decaris has no effect on pinworms!

Look at the indications: ascariasis, necatoriasis, hookworm disease. The last two are also roundworms and are much less common than roundworms.

How does it work"?

In Russian, it causes muscle paralysis in helminths and also disrupts the energy processes in the body of an illegal immigrant.

Well, if the energy is at zero and the muscles are relaxed, nothing prevents them from being calmly expelled from the intestines. Moreover, you don’t even need laxatives. Everything happens naturally, thanks to intestinal peristalsis.

Forms of release and mode of administration

150 mg tablets are indicated for adults. It only takes one pill to paralyze a parasite.

50 mg tablets are prescribed to children 3-14 years old.

Why are there 2 tablets in the package? Because depending on age, ½ to 2 tablets are recommended once.

To be on the safe side, you can repeat the dose after 7-14 days.

What side effects might there be?

Headache, dizziness, cramps, palpitations, nausea, vomiting, abdominal pain.

Who is it contraindicated for?

Nursing women, children under 3 years of age. For pregnant women only under strict indications.

What to say when selling?

  • Take Decaris after meals.
  • You should not drink alcohol for 24 hours after taking it.
  • After 1-2 weeks, repeat the course.

Mebendazole (Vermox, Wormin)

What helminths does it work on?

The action of this anthelmintic extends to a much larger list of helminths than Dekaris. But it works best on pinworms and whipworms.

Indications: enterobiasis, ascariasis, capillariasis, strongyloidiasis, trichinosis, hookworm disease, taeniasis, echinococcosis, alveococcosis, trichocephalosis, gnathostomiasis.

How does it work?

Didn’t I tell you that helminths have a sweet tooth? They love glucose, which is consumed by the owner. By the way, this can explain the frequent feeling of hunger during helminthiasis.

In addition, they need glucose like air, since it is involved in the synthesis of ATP, the main source of energy for the life of most living creatures.

Vermox disrupts the absorption of glucose by worms, which means that ATP synthesis is also disrupted. The helminth's strength leaves.

It is practically not absorbed in the intestines, so it works directly in the enemy’s lair.

Reception mode

The dose and regimen depend on the age and type of helminth. For example, with enterobiasis, a 10-year-old child needs 1 tablet to deal with an illegal immigrant. But it is better to repeat the course after 2-4 weeks.

And for ascariasis, you will need 6 tablets (a whole package) to kill a dependent, since in this case you need to take 1 tablet 2 times a day for 3 days.

Other helminths require different tactics. See instructions.

Abdominal pain, nausea, dizziness.

Who is it contraindicated for?

Children under 2 years old, pregnant and lactating women.

What to say when selling?

  • After 2-4 weeks the course must be repeated.
  • Alcohol should not be consumed within 24 hours after taking it.
  • Fatty foods enhance the absorption of the drug into the blood. While you are being treated with Vermox, try to avoid fatty foods.

Pyrantel (Pyrantel, Helmintox)

What helminths does it work on?

Effective on pinworms, roundworms, hookworms, whipworms.

In medical terms it will sound like this: enterobiasis, ascariasis, hookworm disease, trichocephalosis.

How does it work?

It works on young and adult illegal immigrants, but it spares the larvae, so repeated use is necessary.

It is very poorly absorbed from the intestines.

Forms of release and mode of administration

This drug is good because it comes in the form of a suspension.

Pyrantel suspension can be given to a child from 6 months of age. Remember last time we said that enterobiasis is very contagious, and an older child can easily infect a younger one?

Age-specific dosages of the suspension are indicated in the instructions, so you don’t need to calculate anything per kilogram of weight. Just open the instructions and read.

The number of tablets depends on age and weight. For example, an 8 year old child will need 2 tablets per dose. Usually, for enterobiasis and ascariasis, a single dose is sufficient, but for combined helminthiases (this also happens), you will have to repeat the dose one or two more times.

What adverse reactions can it cause?

When taking it, you may experience abdominal pain, nausea, vomiting, dizziness, headache, rash, drowsiness or insomnia.

Who is it contraindicated for?

  • Nursing.
  • With caution - pregnant women and people with liver failure.

What should you say when selling?

  1. Take Pirantel during or after meals, chewing the tablets thoroughly and drinking a glass of water.
  2. For car enthusiasts: it may cause drowsiness, so it is better not to drive while taking this drug.
  3. After 3 weeks it is advisable to repeat the course.

Piperazine adipate (Piperazine)

A good old, although forgotten, anthelmintic.

Who does it affect?

For roundworms and pinworms (ascariasis, enterobiasis).

How does it work?

Causes paralysis of the muscles of helminths.

Neutralizes 90-95% of enemy units the first time. The second time - 100%.

It is quickly absorbed into the blood and excreted mainly by the kidneys. This explains the side effects, which are discussed below.

But in general, this is a low-toxic drug.

Forms of release and mode of administration

Previously there were tablets of 0.2 and 0.5 g. Now only 0.5.

Drink Piperazine 1 hour before meals or 0.5-1 hour after meals in age-specific dosages. For example, adults need to take 3 tablets at once. And so 2 times a day.

For ascariasis, take 2 days in a row, for enterobiasis, 5 days. In the latter case, it is recommended to take another 1-2 courses, taking a week break between them.

What side effects does it cause?

Abdominal pain, nausea, headache.

If kidney function is impaired, there may be tremors, euphoria, hallucinations, and impaired coordination of movements.

Who is it contraindicated for?

  • Pregnant, nursing. Security not established. Although I read in other sources that this is the only drug approved for use by pregnant women. In general, be careful with pregnant women, and if you take responsibility for advising something, recommend only not in the first trimester.
  • Persons with chronic renal failure and organic diseases of the central nervous system.

What to say when selling?

  1. Take it an hour before meals or 30 minutes to 1 hour after.
  2. At night, do an enema (4-5 glasses for adults, 1-2 glasses for children) to mechanically remove worms.
  3. After a week, repeat the course (for enterobiasis).

Albendazole (Nemozol)

What helminths does it work on?

  • For roundworms: roundworms, pinworms, hookworms, whipworms, etc. (ascariasis, enterobiasis, hookworm disease, necatoriasis, trichuriasis).
  • For intestinal acne - the disease is called strongyloidiasis (it’s still that kind of rubbish: many organs are affected, but most often the bile ducts).
  • Pork tapeworm larvae (Neurocysticercosis).
  • Echinococcus (echinococcosis).
  • Giardia.
  • Toxocara is the causative agent of toxocariasis (common helminthiasis in dogs).

How does it work?

It is poorly absorbed from the intestines, but eating fatty foods increases absorption into the blood 5 times, which means there will be more side effects.

Forms of release and mode of administration

Nemozol is available in the form of chewable tablets, suspension and film-coated tablets.

Take it during meals or immediately after.

The dose and course depend on the type of helminth and the patient’s body weight.

Who is it contraindicated for?

Pregnant women, persons with retinal damage.

Caution: nursing mothers, people with liver failure and hematopoietic disorders.

What side effects does it cause?

There are a lot of them, and they are serious, so I would not advise you to take it upon yourself and recommend this drug yourself.

See what could happen:

  • Liver dysfunction
  • Leukopenia, agranulocytosis, thrombocytopenia,
  • Acute renal failure,
  • Increasing A/D,
  • Meningeal symptoms
  • Well, and more harmless ones: abdominal pain, nausea, vomiting, headache, dizziness, reversible alopecia, itchy skin, rash.

Has a teratogenic effect. Therefore, during treatment with it and for a month after its completion, reliable contraception is required!

During treatment with Nemozol, you need to take a blood test regularly, once every 2 weeks.

What to say when selling?

  1. For a woman: during treatment and for another month after the end of treatment with this anthelmintic, you need to protect yourself from pregnancy.
  2. While you are being treated with this drug, avoid fatty foods and grapefruits as they increase the absorption of the drug into the blood and increase the likelihood of adverse reactions.
  3. Take it with or immediately after meals.
  4. For car enthusiasts: the drug may reduce the reaction, so they are not recommended to drive during treatment.

Praziquantel (Biltricide)

This is exactly the drug that I talked about at the beginning.

Indications:

  • Infections caused by schistosome worms (Schistosoma haematobium, Schistosoma mansoni, Schistosoma intercalatum, Schistosoma japonicum, Schistosoma mekongi). Their common name is schistosomiasis.
  • Infections caused by liver and lung flukes (Clonorchis sinensis, Opistorchis viverrini, Paragonimus westermani). Have you heard about opisthorchiasis? It occurs when eating contaminated, poorly cooked fish.

Both of them have suckers in order to securely attach to the host’s body, which is why they are called “flukes.”

How does it work?

Quickly and completely absorbed from the gastrointestinal tract into the blood.

Forms of release and mode of administration

Available in film-coated tablets, 6 tablets per package.

Take the drug without chewing, after meals. Treatment lasts only 1 or 2 days depending on the type of helminth.

The tablets can be taken once, twice or three times a day. This also depends on the type of illegal immigrant.

The instructions clearly state single dosages by weight.

If you have to dispense this drug, do not be lazy to count the number of tablets per course. Perhaps one package will not be enough.

What side effects does it cause?

Abdominal pain, nausea, vomiting, headache, itching, fever.

Who is it contraindicated for?

  • Patients with impaired liver function.
  • Pregnant women (especially strictly contraindicated in the 1st trimester) and lactating women. Breastfeeding should not be done during treatment with the drug and for another three days.
  • Children under 4 years old.

What to say when selling?

  • Take the tablets without chewing after meals.
  • For car enthusiasts: it is better not to drive while being treated with this drug.

Conclusions:

If we are dealing with ascariasis, Dekaris, Vermox or Piperazine are quite suitable, but they are weaker.

If the uninvited guests are pinworms, Vermox and Pirantel will deal with them wonderfully, and there is no need to use heavy artillery in the form of Nemozol. You can get by with Piperazine, but you will have to give it for 5 days.

If a family with pinworms has a child aged 6-12 months, only one drug is suitable for him: Pyrantel in suspension.

Nemozol and Vermox act on tapeworms (pork tapeworm, echinococcus, alveococcus, etc.). The latter is weaker, but less toxic.

And if illegal immigrants are flukes, the main drug here is Biltricide.

If some helminths are not listed in the instructions, then remember that three drugs have the widest spectrum of action: Nemozol, Biltricid and Vermox.

Strictly contraindicated for pregnant women:

Mebendazole (Vermox), albendazole (Nemozol).

Strictly contraindicated for nursing mothers:

Levamezole (Dekaris), mebendazole (Vermox, Wormin), Pyrantel.

Complex sales for helminthiasis

And finally.

Exercise for the mind

And finally, two math problems.

Just to solve them, you will have to take the instructions:

Problem number one

The family lives: mother, father, grandmother, 6-year-old son and 8-month-old daughter.

A little son (6 years old) came to his father and showed him a piece of paper from kindergarten, where it was written in red ink that, they say, your child has been diagnosed with pinworms, treat it urgently!

Attention, question:

Which drugs and in what quantity would you recommend to this dad?

Problem number two

The Paramonov family consists of a mother, father, an 8-year-old son and another 3-year-old son. One morning, oh, horror, my mother found little white worms in the stool of my youngest. Mom immediately, headlong, flew to you, to the pharmacy.

Attention, question:

What will you offer her, and how many packages?

And very, very finally:

You may have been asked about pumpkin seeds and garlic enemas: they say they are very effective for helminthiasis.

What will I tell you:

About pumpkin seeds: they actually work on some worms (although history is silent on which ones). But for results to be achieved, a single dose of seeds must be 300 grams! As for the coursework, only God knows.

Although, if the pharmacy has them in stock, you can offer them in combination with an anthelmintic.

Regarding the garlic enema.

Write down the recipe.

Take a head of garlic. Grind. Pour a glass of water and bring to a boil. Cool, strain, put into a syringe and administer rectally to MOM or DAD, who was going to give his little blood such an execution.

Better yet, add the juice of one onion to the garlic and add the SAME.

Perhaps the helminths burst into tears from the juice of onions and sneeze from the smell of garlic, but this is unlikely to have any effect on their health and existence. But the child’s rectal mucosa will be seriously damaged.

On this sad note, let me end our conversation for today.

With love to you, Marina Kuznetsova

A small group of medicines, which in pharmaceuticals are called anthelmintics, is of increased interest among consumers. Of course - after all, from TV screens, and on the pages of newspapers and magazines, and on popular websites, we are frightened with loud statements about “terrible and terrible” helminthiases that have affected almost every first inhabitant of the planet. They say that most health problems are associated with helminthic infestations, ranging from discomfort after eating to almost cancer.

The hype about total helminthiases could not help but affect parental experiences. As soon as a child complains of stomach pain or refuses to eat, mothers are already wondering: what anti-worm tablets can be used for prevention, “just in case.” You never know - the child fussed around in sandboxes, ate unwashed or insufficiently washed fruits and vegetables, hugged cats and dogs, and possibly became infected.

Who are you, worm?

But before we begin a detailed acquaintance with the drugs of this group, it would be good to find out what helminthiases actually are.

There are also other, rarer types of helminthic infestations, which we will not mention - the likelihood of getting sick from them is too scanty.

An inquisitive reader may be surprised: why does he need to know all these complex, incomprehensible names of diseases? It's simple - anti-worm tablets, which are sold in Russian pharmacies, are classified depending on what specific type of helminth they affect.

Classification of drugs for worms

In modern pharmacology, several classifications of anthelmintic drugs are used, based on various characteristics of the drugs.

Thus, the classification by pharmacological action divides all anthelmintics depending on what type of worms they adversely affect. In accordance with it, they distinguish:

  • anti-nematode tablets against worms (piperazine adipate, mebendazole, pyrantel, wormwood flowers, tansy);
  • anticestodiasis (fern extract, pumpkin seeds);
  • protrotrematodous.

Classification according to the mechanism of action divides anthelmintics into:

  • drugs that disrupt the functioning of the neuromuscular system of roundworms, nematodes (pyrantel, piperazine adipate, levamisole);
  • drugs that paralyze the neuromuscular system in flatworms;
  • drugs that have a negative effect on the energy processes of worms (mebendazole).

There is also a classification based on chemical structure, but in order not to frighten the reader with the complex names of the active ingredients included in the anti-worm tablets, we will not dive into its subtleties, but will move directly to the description of the drugs. And we will start with a product that has been sold in pharmacies for many decades.

Piperazine - anti-worm tablets for humans and animals

The organic compound piperazine adipate was first proposed as a deworming agent back in 1953. Its anthelmintic effect is based on the ability to paralyze the muscles of nematodes. Piperazine exhibits the highest activity against ascariasis and enterobiasis. According to research, even after a single use, the effectiveness of the medicine ranges from 90-95%, and with repeated use it reaches 100%.

Piperazine is produced in the Russian Federation in the form of tablets with the same name. Their distinguishing feature is their very low cost. However, despite its cheapness, Piperazine as a medicine for worms for the treatment of humans today is not popular either among doctors or among consumers. The reason for this is rather poor tolerance. After taking the drug, there are frequent cases of nausea, vomiting, abdominal pain, bowel dysfunction, in particular diarrhea. Allergic reactions are possible.

Today, piperazine adipate is practically not used in medicine. But it is used in veterinary medicine to treat helminthic infestations in animals.

Levamisole: time-tested!

Much more often today, another “experienced” drug is used - Levamisole hydrochloride. It, like piperazine, has a low cost. True, imported products based on Levamisole are somewhat more expensive than domestic ones. The drug is registered in Russia under the trade names Levamisole (domestic analogue) and Dekaris, produced by the famous Hungarian company Gedeon Richter.

The history of Levamisole has been going on for more than half a century - it was discovered in 1966, and since then it has been invariably used to treat helminthic infestations in adults and children. The World Health Organization has included Levamisole in its famous list of drugs of vital importance to human health.

The antihelminthic effect of Levamisole is due to its ability to disrupt the energy metabolism of helminths and especially roundworms. Under the influence of the tablets, the worms become paralyzed, and they are eliminated from the body naturally within 24 hours after taking them.

Along with ascariasis, Levamisole is also used for other helminthic infestations, such as enterobiasis, trichuriasis, and so on. In addition, the drug is also prescribed for toxoplasmosis.

An imported analogue of Levamisole, Dekaris is available in two dosages - for children 50 mg and for adults 150 mg. For the treatment of worms in children, depending on age, a dose of 25-100 mg is prescribed, and for adults - 150 g. In both adult and pediatric practice, the tablets are taken once, in the evening, with a moderate amount of water.

How is Levamisole tolerated?

The safety of Levamisole, like Piperazine, is not all smooth sailing. Even a single dose can be toxic to the body, especially a weakened one. Side effects of this medicine are divided into:

  • gastrointestinal - nausea, abdominal pain, diarrhea, vomiting;
  • neurological - headache, fatigue, insomnia, change in taste;
  • changes in the blood system - a decrease in the number of leukocytes, sometimes severe;
  • allergies, in particular rashes.

In addition, sometimes taking Levamisole is accompanied by impaired renal function, gynecological bleeding and other undesirable reactions.

To avoid the development of complications, experts recommend at least a general blood test before taking Levamisole and a few weeks after treatment.

And one more feature of Levamisole: it is incompatible with alcoholic beverages. When taken together with alcohol, the drug causes a so-called disulfiram-like reaction, on which the principle of action of the drug for the treatment of alcoholism Esperal is based. Levamisole blocks the breakdown of the intermediate breakdown product of ethyl alcohol, acetaldehyde, which, when accumulated in the blood, contributes to the development of intoxication. The latter is accompanied by nausea, vomiting, headache, weakness, and in severe cases, confusion and other effects.

Due to serious adverse reactions in many countries around the world, including the United States and Canada, Levamisole is prohibited for use as a deworming drug for humans. But in the post-Soviet space it is still used, although not as often as ten to twenty years ago.

Additional properties of Levamisole

It is impossible not to mention the effects of Levamisole, which, although they have nothing to do with the anthelmintic effect, are nevertheless widely used in medicine. And sometimes even wider than the main effect.

First of all, clinical studies have confirmed the effectiveness of Levamisole in combination with the oncological drug fluorouracil in the treatment of colon cancer. There is evidence of positive results in the treatment of malignant neoplasms of the breast and bronchi with Levamisole, as well as in the treatment of leukemia, rheumatoid arthritis and other diseases.

Levamisole is supposed to stimulate the immune system, and some doctors prescribe it as an immunomodulator, including for influenza and ARVI. However, this practice causes skepticism among many specialists, based on the fact that, firstly, Levamisole is quite toxic, and secondly, its immunostimulating effect has not been confirmed in serious clinical trials.

Anti-worm tablets Pirantel

  • pinworms;
  • roundworms;
  • hookworms.

The effect of Pyrantel is due to its ability to cause permanent paralysis of the muscles of sensitive worms, which then naturally leave the body. In this case, the drug works regardless of the sexual maturity of the worms, but is not effective against the larvae.

Pyrantel is used to treat worms in adults and children weighing more than 12 kg. The course of treatment depends on what type of invasion is detected:

  • when infected with pinworms and roundworms, the drug is used once, calculating the exact dosage depending on the weight of the child or adult. To prevent reinfection (re-infection), Pirantel is taken again after 3 weeks.
  • when infected with hookworms, Pirantel is prescribed for 2-3 days based on the patient’s weight.

The convenience of Pirantel is that for the treatment of young children, not traditional tablets are produced, but a special, pediatric form for worms in the form of a suspension. For children over 6 years of age, it is more convenient to give tablets at a dose of 125 mg. Well, Pirantel for adults is produced in tablets with a dose of 250 mg.

Pyrantel is much better tolerated than Piperazine and Levamisole. Occasionally, side effects may develop, such as nausea, abdominal pain, allergies and some others, but more often adverse reactions are not observed when taking therapeutic doses.

And one last thing. There are several analogues of Pirantel on the Russian market, including:

  • Helmintox, a French medicine for worms. It is distinguished by high quality and higher cost compared to other analogues;
  • Nemotsid, produced by an Indian company. More economical compared to the French product;
  • Pirantel, under this name, a number of drugs for worms are produced, including Russian, Polish, and Indian.

Albendazole: a popular broad-spectrum dewormer

The next drug is radically different from those we have already described. Albendazole was synthesized in 1975 by pharmacists of the world famous company Glaxo. Just like Levamisole, it is included in the WHO list of drugs vital for human health.

Unlike Levamisole and Piperazine, Albendazole deworming tablets have a wide spectrum of action, including roundworms, cestodes and nematodes. Thus, it has an anthelmintic effect against most helminths, so the drug is used for many helminthiases, including:

  • ascardiasis;
  • enterobiasis (infection with pinworms);
  • toxocariasis;
  • echinococcosis;
  • trichinosis and others.

Albendazole is available in adult and pediatric dosage forms. For children over 6 years of age, tablets with a dose of 200 mg are intended, for adults - tablets of 400 mg. For babies over 1 year of age, it is better to offer a pediatric suspension. Some manufacturers offer a convenient form of Albendazole in the form of chewable tablets that do not need to be washed down with water.

The dosage and course of treatment are calculated based on the type of disease, age and weight of the patient.

When infected with roundworms and pinworms, it is recommended that an adult take 1 tablet of Albendazole with a dosage of 400 mg once, a child over 6 years old - a tablet with a dose of 200 mg once, and for children aged 1 to 6 years, a suspension is ideal, 5 ml of which contains 100 mg of the active substance ( the full therapeutic dose in this case is 10 ml).

In order to prevent re-infection, it is recommended to repeat single doses of Albendazole three weeks after treatment for both adults and children.

Safety and analogues of Albendazole

In general, Albendazole is well tolerated. However, it is possible that a number of side effects may occur, including:

  • nausea, abdominal pain, constipation or diarrhea, bloating;
  • changes in blood picture, increased blood pressure;
  • insomnia or, conversely, drowsiness, headache and dizziness, blurred vision (temporary);
  • allergies, which most often manifest as rash and itching.

During pregnancy, Albendazole is strictly contraindicated: according to the FDA classification, it belongs to category C. This includes drugs that have demonstrated side effects on the fetus in animal studies. In order to exclude a possible teratogenic effect, Albendazole should not be taken by women who are planning a pregnancy at least one month before conception.

And about analogues. There are several generic products containing Albendazole on the Russian market. Among them:

  • Nemozol produced by the Indian company Ipka has a wide range of release forms (chewable tablets, film-coated tablets and children's suspension). It is economical and of fairly high quality, meeting modern requirements for drugs;
  • Sanoxal, a less popular deworming remedy, also made in India, is available only in the form of chewable tablets for adults with a dose of 400 mg;
  • Gelmodol-VM, tablets with a dose of 400 mg, produced in Egypt.

Domestic companies do not produce Albendazole, but they produce another drug against worms, which is very similar to it structurally and in its mechanism of action - Mebendazole.

Antihelminthic Mebendazole: features of the drug

And the last noteworthy anthelmintic drug, Mebendazole, synthesized in the early 70s by Belgian pharmacists, is one of the most commonly used anthelmintic drugs. It also belongs to the list of vital means for human health.

The features of the pharmacological action of Mebendazole are very similar to the mechanism of action of Albendazole: it also blocks the production of ATP, disrupts the excretion of glucose in the tissues of worms and contributes to their death.

Unfortunately, there is no release form for Mebendazole for young children. Only 100 mg deworming tablets are available. They can also be given to children over 2 years old, dividing the tablet into parts (children's dose at the age of 2-10 years is about 25-50 mg). However, such a division will be very arbitrary - the tablets do not have marks, and an attempt to calculate “by eye” what part of it will be 25 mg is unlikely to be very successful. Therefore, it is still better not to use Mebendazole tablets for the treatment of worms in children under 10 years of age, especially since there are children's forms of the same Albendazole or Pyrantel.

The duration of treatment with Mebendazole depends on what type of helminth the infection occurred.

So, when adults or children over 10 years of age are infected with pinworms, it is enough to take a tablet with a dose of 100 mg once. Sometimes (but not always, only in case of re-infection) the drug is re-prescribed after a few weeks at the same dosage.

When infected with roundworms, Mebendazole is taken for three days in a row, two tablets per day (one in the morning and one in the evening).

Tolerability of Mebendazole and its analogues

Despite the fact that Mebendazole is usually tolerated without problems, the likelihood of developing side effects while taking it still exists. Among them, “traditional” for deworming tablets are nausea and abdominal pain, changes in the blood picture, and allergies. Headache and drowsiness are also possible. In addition, during treatment with Mebendazole, changes in urine analysis (the appearance of blood in the urine and others) are not excluded.

In Russian pharmacies you can buy several analogues of Mebendazole, and the most popular of them is the product of the Hungarian company Gedeon Richter Vermox. Indian Vormin is in less demand. The domestic analogue of Mebendazole, called Vero-Mebendazole, can be classified as one of the inexpensive drugs that are of fairly high quality.

Herbal anthelmintic drugs

And finally, we just have to take a closer look at herbal medicines for worms. They are often used in folk medicine and can be included in a combination treatment regimen along with medications.

Tansy flowers

One of the most famous medicinal plants that are used in the treatment of helminthiases is tansy. For medicinal purposes, small yellow flowers collected in inflorescences-baskets are used.

The pharmacological effect of tansy flowers is due to the content of active substances in them, in particular, essential oil, flavonoids and alkaloids. They exhibit an anthelmintic effect, primarily directed against two types of helminths - roundworms and pinworms. Therefore, tansy flowers are used only for two types of helminthic infestations.

An infusion is made from tansy flowers, which is taken several times a day (2-3) in a dose of approximately 50-70 ml. The course of treatment can last several weeks. To ensure that the therapy was effective, it is important to conduct laboratory testing at the end of treatment. And lastly: despite the fact that tansy infusion is a natural, natural preparation, it cannot be used during pregnancy.

Pumpkin seeds

If an infestation by tapeworms is detected, a decoction of pumpkin seeds can be used as an additional remedy, while the main treatment of worms should be carried out with the help of medications.

Rules for treatment with drugs for worms

It would seem that there could be no wisdom: I took one tablet at night and forgot about the worms as if it were an unpleasant dream. But there are actually a few things to keep in mind.

Firstly, effective treatment of worms should involve not only taking pills, but also hygienic measures to prevent re-infection. To prevent this from happening, it is important to remember that:

  • After visiting the toilet and before eating, you must wash your hands thoroughly with soap;
  • the patient's bed linen and underwear must be changed daily, washed at high temperature and ironed with a hot iron on both sides;
  • The house must be wet cleaned every day using disinfectants.

Secondly, it is important to take measures to prevent family members from becoming infected. Again, this can be achieved by scrupulously following hygiene requirements.

When treating laboratory-confirmed helminthiasis, some doctors recommend preventive therapy for worm infection for all family members. However, this issue remains controversial and controversial.

Thirdly, during treatment with Albendazole and Mebendazole, it is important to stop drinking alcoholic beverages for 3-5 days. The requirement is due to the disulfiram-like effect of these two drugs. Otherwise, intoxication develops, whose symptoms resemble alcohol poisoning. This rule does not apply to other anti-worm tablets (Dekaris, Pirantel).

And another important question that worries many consumers is whether it is necessary to take antihelminthic drugs prophylactically, “just in case.” He deserves special attention.

Tablets for the prevention of worms: benefit or harm?

The need for preventive administration of tablets against worms is still the subject of ongoing debate both among consumers and among doctors. And the opinions of the latter differ on this matter.

Some doctors believe that prevention of worm infection, including in children, is justified if the child or adult is at risk. Indications for periodic preventive therapy in this case include:

  • regular contact with pets (dogs, cats);
  • contact with sand, earth;
  • fishing or hunting.

Children who attend kindergartens and schools are also at risk.

To prevent the most common infections, it is recommended to take deworming tablets, preferably broad-spectrum, twice a year.

However, opponents of prophylactic antihelminthic tablets make compelling arguments against preventive tactics.

Arguments against prevention

The most important counterargument in the debate between supporters and opponents of helminthiasis prevention is the rather low safety profile of anti-helminthic drugs. As we have already seen, they cannot be called very well tolerated. Cases of side effects when taking them are quite common. Moreover, there are situations where treatment with anthelmintics was accompanied by severe adverse reactions requiring medical attention.

Thus, taking paralyzing anthelmintics can be quite dangerous, in particular if a person has a partial intestinal obstruction. It develops as a result of various neoplasms, both benign and cancerous, as well as against the background of other diseases. Alas, in some cases, partial obstruction may not make itself felt. If such a patient takes Decaris or Pirantel, the paralyzed helminths can block the lumen of the already narrowed intestine, and then the patient needs emergency surgery.

In addition, many experts are categorically against the prevention of worms in children and adults who do not have clinical symptoms of infection. The fact is that helminth infection very rarely occurs hidden. Usually the disease has a fairly pronounced clinical picture, including:

  • abdominal pain;
  • nausea, sometimes even vomiting;
  • fatigue, restless sleep, especially in children;
  • pallor, blue circles under the eyes, weakness;
  • itching in the anal area;
  • weight loss, stunting in children.

What to do if symptoms of worm infection appear?

If alarming signs appear, it is necessary to consult a doctor and diagnose helminthiasis, and it is important to find out what type of worm the infection occurred. Diagnostic difficulties should also be taken into account. According to statistics, only one out of five patients is diagnosed with enterobiasis (pinworm infection) during the first examination of the material. False negative results are also very likely when infected with roundworms. Therefore, you may have to undergo tests more than once to accurately determine the diagnosis.

And yet, storming laboratories to make sure of infection or, on the contrary, its absence, is much safer than randomly taking “incomprehensible” pills for worms ourselves or, moreover, giving them for prevention to children, especially at their own request, without doctor consultations. It’s not for nothing that all anthelmintic drugs are prescription drugs. Take pity on your body - it most likely has to fight hard for your health when polluted air enters your lungs, and genetically modified products, preservatives and other chemical achievements enter your digestive tract. Do not load him with anti-helminthic tablets unless necessary, which is a laboratory confirmed diagnosis. And if the disease is confirmed, give the doctor the right to prescribe medications and a course of treatment. And then you can be sure of success.

Artificial and semi-synthetic tablets have a more powerful effect compared to their herbal counterparts. They not only kill helminths, but also quickly remove toxic waste products from the body. In addition, most medications are used to get rid of extraintestinal invasions.

The main types of medicines for worms

  • medications against cestodosis;
  • medications for trematodiasis;
  • means against nematodes.

Medicines do a good job with adult worms, while the effect of medicines does not apply to worm larvae and eggs. They remain practically unharmed, so patients are prescribed a second course of anthelmintic drugs a couple of weeks after the first.

Anticestodoses

Antitrematodose therapy

Dealing with flukes is not easy even with the appropriate medications. The thing is that these medications can only be used by adults and only in the absence of contraindications. The drugs are highly toxic, so in some cases their use is fraught with the development of serious side effects. In patients taking anti-trematode drugs, the liver becomes enlarged, the heart rhythm becomes erratic, and pain in the sternum is possible. Allergy sufferers should be especially careful when using such medications, since individual intolerance to the drug can lead to angioedema or anaphylactic shock.

If the described symptoms appear, you should immediately seek medical help. Specialists will assess the risk of taking medications and the advisability of using the medication in the future. Anti-trematode anthelmintic drugs for humans should not be prescribed to pregnant and nursing mothers, patients with heart or liver diseases.

Treatment of nematodosis

Helminthiasis, which is characterized by the presence of roundworms in the intestines, usually does not lead to complications. The therapeutic program for this infectious disease itself is considered the simplest. Taking antinematode drugs is accompanied by adverse reactions only in exceptional cases, since they are characterized by relatively low toxicity and a high level of effectiveness.

A pronounced clinical picture, indicating infection with worms, allows the doctor to promptly draw conclusions about the stage of the disease and refer the patient to undergo diagnostic procedures. As soon as the test results reveal what type of worms the patient’s body is affected by, the specialist will be able to prescribe a broad-spectrum anthelmintic drug. For people, they most often use means, which you can learn about in more detail below.

"Pirantel"

The drug is available in tablets and suspensions. Despite the low concentration of toxic substances, Pirantel is very effective. With confirmed enterobiasis (caused by pinworm) and ascariasis, you only need to take the drug once. The dosage is calculated by the attending physician, adhering to the formula of 10 mg of the active substance of the same name per 1 kg of body weight. For other types of helminthic infestation, longer use is required (on average 2-3 days).

It is not advisable for pregnant women to take Pirantel, although the use of this drug is not excluded if the benefit to the mother outweighs the potential risk to the unborn baby. Side effects, judging by reviews of the anthelmintic drug, are extremely rare in people. The cause of nausea, vomiting, other dyspeptic disorders, and headaches may be non-compliance with the dosage during a prolonged course of treatment. The advantages of Pirantel include its price - in pharmacies in our country, a package of this drug costs no more than 100 rubles.

"Helmintox"

Contraindications to the use of the drug are similar to those present with Pirantel. It is also important to know that this product contains allergenic auxiliary components (for example, sorbitol, ascorbic acid, povidone, polysorbate). In case of individual intolerance to these substances, therapy with Helmintox should be discontinued.

"Dekaris"

This medicine is considered one of the best anthelmintic drugs for humans. The main substance is levamisole. The medication is taken once, is approved for both adults and children over three years of age, and is produced, respectively, in different dosages: for children (50 mg in one tablet) and for patients over 14 years of age (150 mg of levamisole per pill). Indications for use of "Dekaris":

  • hookworm disease;
  • nekarotosis;
  • ascariasis;
  • enterobiasis.

A full course of deworming requires about 24 hours. Levomisole does not accumulate in tissues and leaves the body almost completely along with urine and feces over the next 6-8 hours after absorption into the blood.

This anthelmintic should be recommended with caution to a person suffering from renal or liver failure. In addition, a direct prohibition for the use of “Dekaris” is a history of diseases of the blood and hematopoietic system, gestation, lactation, early childhood and allergies. The cost of "Dekaris" varies between 80-90 rubles. per package.

"Albendazole" and "Mebendazole"

An analogue of Albendazole is the drug Mebendazole, which is similar in principle of action and price. Both drugs have a wide spectrum of action and are used for the treatment of single and multiple infestations of roundworms, cestodes, and trematodes. The drugs are available in a loading dose of 400 milligrams. The products are available not only in tablet form, but also in the form of syrup. During pregnancy, with pathologies of the organs of vision, hematogenous diseases, the drug should not be taken. Compared to previous medications for worms, this has a higher price - it is sold in pharmacies with a prescription for 200-250 rubles.

"Vormil"

Antihelminthic drugs for humans containing albendazole have a wide spectrum of action. "Vormil" is no exception. This remedy can be used for any intestinal and extraintestinal helminthic infestations, as well as for prophylactic purposes. The drug is available in the form of chewable tablets with fruit flavor. The duration of therapy with Vormil in severe cases can reach 30 days.

"Vermox"

Suspensions and drops

Medicines in drops are diluted with water before taking. This form is convenient to use for people who have difficulty swallowing. Antihelminthic drops are prescribed to children and elderly patients. However, most of the drip remedies for worms do not belong to the category of medicines, but are bioactive food additives.

Dietary supplements for worms: do they help?

In addition, it should be remembered that such drugs are not tested in laboratories and do not undergo full clinical trials, unlike pharmaceutical drugs. Therefore, it is not advisable to take them to treat helminthiasis. They are effective at best in preventing invasion.

Which anthelmintic drugs for humans are suitable for pregnant women

The spectrum of action of this drug is limited (it helps only with enterobiasis and ascariasis), so it is recommended to supplement therapy with natural anthelmintic agents. Pregnant women, for example, are advised to consume raw and ground pumpkin seeds. It is not advisable to fry or boil them - the seeds will lose their healing properties.

Contraindications to drug therapy vary depending on the specific drug. Among those described above, Mebendazole and its analogues have the greatest number of restrictions in use. They should not be used by patients with diseases such as:

  • heart failure;
  • Crohn's disease;
  • stomach or duodenal ulcer;
  • nonspecific ulcerative colitis;
  • liver or kidney failure;
  • cholelithiasis;
  • moderate anemia, leukopenia;
  • retinal lesions.

Other anthelmintic drugs, including natural formulations based on tansy and wormwood, are not recommended to be taken during pregnancy and breastfeeding. Any tablets and suspensions for worms should be prescribed with caution to children under two years of age. An allergy to any of the components of the drug is an absolute contraindication to its further use.

Drug prevention

  • wash your hands thoroughly with soap before eating, after going outside, being in public places and visiting the toilet;
  • consume meat and fish products only if they have undergone the necessary heat treatment;
  • drink only boiled water;
  • include raw onions, garlic, and red peppers in your diet.

It is not advisable to use tansy as a preventive measure. This plant also contains toxic compounds that, if not taken in the correct dosage, can harm the liver and kidneys.

It should be remembered that timely deworming of cats and dogs plays an important role in the prevention of human helminthiasis.
Puppies and kittens: first deworming at two weeks of age, then monthly until 6 months.
Adult animals: deworming every three months.
Pregnant cats and bitches: deworming two weeks before birth and two weeks after.
It is recommended to deworm animals before vaccination, before mating, and also if there is a risk of re-infection with helminths.
Attention! Many helminths found in our pets (echinococci, roundworms, tapeworms) are dangerous for humans, especially for children!
Fleas are carriers of helminth larvae, so deworming should be carried out in conjunction with treating the animal with insecticidal preparations against fleas.

Endoguard

Dose and method of administration: The drug is administered to dogs once during feeding. Endoguard It is highly palatable to dogs and is usually easily eaten by hand. If the dog refuses to eat, the tablet is given in crushed form with a small amount of food or injected forcibly onto the root of the tongue after feeding.

Endoguard 10: For weight: 2.5-5kg - 0.5 tablets,
6-10kg - 1 tablet,
11-15kg - 1.5 tablets,
16-20 kg - 2 tablets.
Endoguard 30: For weight: 11-15kg - 0.5 tablets,
16-30kg - 1 tablet,
31-45 kg - 1.5 tablets,
45-60kg - 2 tablets.

For the treatment of giardiasis Endoguard used in the usual dosage, once a day, for three days. A preliminary starvation diet and the use of laxatives before deworming are not required. In order to prevent dirofilariasis in regions unfavorable for the disease, the drug is used in the spring-summer-autumn period (April-October): a month before the start of the summer season of mosquitoes and mosquitoes (carriers of the disease pathogen) once, then once a month and the last time in the season two months after the end of insect flight.
Pregnant and lactating bitches Endoguard can be used if necessary, strictly observing the dosage.

Contraindications: Do not use simultaneously with piperazine. Endoguard should not be used on puppies younger than 2 weeks of age.

Compound:
Endoguard 10(per tablet 0.9g): febantel 150 mg, pyrantel pamoate 144 mg, praziquantel 50 mg, ivermectin 0.06 mg, auxiliary components up to 900 mg.

Endoguard 30(per tablet 2.7g): febantel 450 mg, pyrantel pamoate 432 mg, praziquantel 150 mg, ivermectin 0.18 mg, auxiliary components up to 2,700 mg.

Dehinel Plus

Tablets are dosed according to the weight of the dogs according to the table:

It is necessary to monitor the ingestibility of the drug. No preliminary fasting diet or use of laxatives is required. Preventive deworming should be carried out 3–4 times a year, as well as before vaccination and mating.
Side effects: in animals hypersensitive to the components Dekhinela Plus Allergic reactions are possible. With proper use and dosage, side effects are usually not observed.
Contraindication: increased individual sensitivity to the drug. Appointment prohibited Dekhinela Plus puppies under 3 weeks of age, pregnant bitches in the first two-thirds of pregnancy, as well as animals sick with infectious diseases and convalescing animals. Simultaneous use is not allowed Dekhinela Plus with cholinergic drugs (levamisole, piperazine, etc.), as well as with organophosphorus compounds.

Dosalid

Dosalid– a medicinal product in the form of tablets for oral administration, intended for deworming dogs.
As active ingredients Dosalid contains pyrantel (in the form of pamoate) and epsiprantel, and lactose monohydrate and microcrystalline cellulose as auxiliary components.
Pharmacological properties: Dosalid has a wide spectrum of anthelmintic action against nematodes and cestodes in dogs, including Toxocara canis, Toxascaris leonine, Uncinaria stenocephala and Ancylostoma caninum. Dipylidium caninum, Taenia hydatigena, Taenia pisiformis, Echinococcus granulosus and Echinococcus multilocularis.
Dosalid insoluble and poorly absorbed in the intestine. The drug is excreted unchanged in feces. At recommended doses Dosalid well tolerated by animals.
Directions for use: Dosalid used in dogs for the prevention and treatment of infestations caused by nematodes (Toxocara canis, Toxascaris leonine, Uncinaria stenocephala and Ancylostoma caninum) and cestodes (Dipylidium caninum, Taenia hydatigena, Taenia pisiformis, Echinococcus granulosus and Echinococcus multilocularis).
The first preventive deworming of puppies is carried out at the age of 2 - 4 weeks, and then every 4 weeks until they reach the age of 6 months, and then after 6 months.
In puppies infected with T.canis, deworming is carried out twice with an interval of 2-3 days. For lactating females, preventive deworming is carried out 2 weeks after the birth of puppies, and then at intervals of 2 weeks until weaning.
It is recommended to deworm lactating females and puppies at the same time. Adult animals undergo regular preventive deworming twice a year from 6 months of age annually.
When treating infestation in adult animals, repeated deworming is carried out after 7-14 days. As a rule, there are no side effects or complications in dogs when using the drug in accordance with these instructions.

Poliverkan(sugar cubes)

Drontal plus
anthelmintic for dogs

Drontal Plus intended for therapeutic and prophylactic treatment of dogs against round and tape helminths.
Compound: praziquantel, pyrantel embonate, febantel.
Dosage and method of application: Drontal Plus prescribed to adult dogs once at the rate of 1 tablet per 10 kg of animal weight. Drontal Plus can be given to puppies, old and weakened animals, whelping and lactating bitches.
For preventive purposes, we recommend treating adult dogs against helminths 4 times a year. This especially needs to be done before vaccination, mating and 10 days before whelping.

Lawyer drops for dogs
from the largest to the smallest dogs

Kanikvantel plus
with meat flavor

Kanikquantel Plus
Compound:
Indications for use: Kanikquantel Plus
1 tablet Kanikquantel Plus per 10 kg body weight.
For cats, as a rule, according to their body weight, 1/2 tablet per animal is sufficient. For ongoing (preventive deworming) it is recommended to repeat treatment Kanikvantelom Plus
Kanikvantelom Plus Kanikvantel plus

Kanikquantel Plus XL
for large breed dogs

Kanikvantel Plus XL broad-spectrum antihelmetic.
Indications for use: the drug is used orally for mixed helminthiasis of dogs and cats caused by round and flatworms. Due to the fact that infection with flatworms in newborn puppies can occur only starting from three weeks of age, treatment with the drug Kanikquantel PlusXL, with a confirmed diagnosis of mixed invasion, should begin no earlier than after reaching the age of three weeks.
Indicated for the prevention and treatment of helminthiases in dogs and cats caused by Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus multilocularis, Echinococcus granulosus, Dipylidium caninum, Taenia spp., Multiceps multiceps
Compound: praziquantel, fenbendazole.
Dosage and method of application: for veterinary purposes only. Apply orally.
1 tablet Kanikquantel Plus XL per 20 kg body weight.
For cats, as a rule, according to their body weight, 1/4 - 1/2 tablet per animal is sufficient. For ongoing (preventive deworming) it is recommended to repeat treatment Kanikvantelom Plus XL every 3 months. In case of particularly severe infection, the dosage is repeated.
When infected with roundworms - especially in young dogs - a single application may not be enough for complete deworming, which can lead to the possibility of infection of people in close contact with the animals. Therefore, for ascaris infestation, treatment Kanikvantelom Plus XL should be repeated after 2-3 weeks. Tablets are administered to animals orally once in a piece of meat, sausage, with minced meat, porridge or on the root of the tongue, preferably before morning feeding and without the use of laxatives. In case of refusal to feed with an anthelmintic, Kanikvantel plus XL administered in the form of an aqueous suspension using a syringe or catheter. No special dietary measures are required.

Milbemax
tablets for small dogs and puppies

Milbemax broad-spectrum antihelmetic. Milbemax


Dog weight quantity
0.5 – 1 kg ½ tablet
1 – 5 kg 1 tablet
5 – 10 kg 2 tablets
5 – 25 kg 1 tablet
5 – 50 2 tablets
50 – 70 kg 3 tablets

Indications for use:

Milbemax
tablets for medium and large dogs


Milbemax broad-spectrum antihelmetic. Milbemax can be given with a small amount of food. Tablets are dosed according to the weight of the animal.
Ingredients: milbemycin oxime, praziquantel.
Tablets are dosed according to the weight of the animal according to the table:
Dog weight quantity
0.5 – 1 kg ½ tablet
1 – 5 kg 1 tablet
5 – 10 kg 2 tablets
5 – 25 kg 1 tablet
25 – 50 kg 2 tablets
50 – 70 kg 3 tablets

Indications for use: prescribed to dogs for preventive and therapeutic purposes for nematodes (toxocariasis, toxascariasis, hookworm disease, trichocephalosis) and cestodiasis (taeniasis, echinococcosis, dipylidiasis, mesocestoidosis). And also for the prevention of dirofilariasis in regions where Dirofilaria immitis is registered.


Helminthal suspension
complex anthelmintic for puppies and dogs against round and tapeworms

Azinox plus
anthelmintic for dogs

Azinox broad-spectrum anthelmintic against tapeworms and roundworms for dogs.
Compound: The active ingredients are praziquantel and levamisole.
Dosage: 1 tablet per 10 kg of body weight, given once. If necessary, repeat after 12-15 days. The drug is given on an empty stomach with a small amount of food or water. Complete feeding of the animal approximately one hour after taking the drug.

Bars spot-on a medicinal product in the form of a solution for external use, intended for the treatment and prevention of nematodes and arachnoentomosis in dogs.
Compound: praziquantel and ivermectin, as well as auxiliary components.
Release Bars spot-on dogs and puppies.
Application: Bars spot-on prescribed to dogs and puppies over 2 months of age for the treatment and prevention of intestinal nematodes, cestodiases, entomoses, otodectosis, sarcoptic mange, demodicosis. Bars stop-on Apply dropwise to dry, intact skin in the area of ​​the shoulder blades. To destroy fleas, lice and hair lice, animals are treated once, to prevent re-infestation once a month throughout the entire season of insect activity. In order to prevent re-infestation by fleas, the animals' bedding is replaced or treated with an insecticidal agent in accordance with the instructions for its use. To treat otodectosis (ear scabies), the drug is applied to the skin once. During the treatment process, it is recommended to clean the ear canal of exudate and scabs, and in case of complications with otitis media, prescribe antimicrobial agents and after 7 days, repeat the treatment with application to the withers.
6. For therapeutic purposes in cases of sarcoptic mange and demodicosis in dogs, the drug is used 2-4 times, with an interval of 10-14 days; in order to prevent possible invasion - 1 time per month.
For deworming of animals with nematodes and cestodes of the gastrointestinal tract, the drug is used for therapeutic purposes once, for prophylactic purposes - once a quarter.
Bars spot-on It is prohibited to use in puppies under 2 months of age, pregnant, lactating animals, patients with infectious diseases and convalescent animals.
In rare cases, if there is increased individual sensitivity to the drug (lacrimation, excessive salivation, muscle tremors, vomiting) or signs of skin irritation, the use of the drug should be stopped and washed off with soap and water. The drug is not recommended for collie, sheltie, and bobtail dogs.

Febtal combo

Febtal combo This is a new anthelmintic suspension created specifically to protect your pet from tapeworms and roundworms.
Now you can drive away worms without stress for your pet - your pet will like the taste of the suspension, and the syringe will help you accurately and effortlessly give the medicine to the animal.
Application: Febtal combo prescribed to dogs and cats for prophylactic and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, trichuriasis, hookworm infection), cestodiasis (tenidosis, dipylidiasis, echinococcosis, diphyllobothriasis, mesocestoidosis) and mixed nematodo-cestodiasis infestations.
Febtal combo They are administered to animals once, individually, in the morning feeding with a small amount of food, or they are administered forcibly.
Before use, the container with the suspension should be shaken thoroughly.
No preliminary fasting diet or use of laxatives is required.
To deworm animals weighing less than 0.5 kg, immediately before use, add 0.3 ml of boiled water in a measured dose of the drug, then shake the container thoroughly and administer the suspension to the animal.
For therapeutic purposes, deworming of dogs and cats is carried out according to indications, for preventive purposes - quarterly in a therapeutic dose.
In case of increased individual sensitivity of the animal to the active components of the drug and the appearance of side effects, the use of the anthelmintic drug is discontinued.
Febtal combo should not be used on pregnant or lactating bitches, as well as puppies and kittens under 3 weeks of age.
Compound: praziquantel and albendazole, as well as auxiliary components.
Dosage: at the rate of 1 ml of suspension per 1 kg of animal weight.

Prazicide suspension
for puppies and dogs

Prazitel
for kittens and puppies

Prazitel is a broad-spectrum anthelmintic drug.
Compound: praziquantel, pyrantel.
Properties: the drug is active against round and tape helminths in animals.
Indications for use: preventive and therapeutic deworming for cestodiases, nematodes and mixed infestations.
Dosage and method of application: 1 tablet per 1 kg of animal weight. Prazitel is given individually, once, in the morning feeding with a small amount of food. With a high degree of infestation, deworming is repeated after 10 days. For preventive purposes, Prazitel is used for kittens once every 3 months, starting at 3 weeks, for puppies at the age of 2 weeks, then at 4-6 weeks, 6 months, depending on the vaccination schedule.
Side effect: side effects and complications during use have not been established. Individual intolerance to the components of the drug is possible.
Contraindications: the drug should not be used in puppies under 2 weeks of age and kittens under 3 weeks of age. Do not use together with piperazine.

Prazitel suspension
for puppies and small breed dogs

Dirofen suspension
for dogs containing pumpkin seed oil

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