Coldflu- a combined medicinal product used for the symptomatic treatment of acute respiratory diseases. The drug has antipyretic, anti-allergic, analgesic and anti-inflammatory effects, reduces the symptoms of rhinitis, and has some stimulating effect on the central nervous system. The mechanism of action and pharmacological effects of the drug are due to the properties of its active components.
Paracetamol- a drug of the group of non-steroidal anti-inflammatory drugs, a derivative of paraaminophenol. The mechanism of action of paracetamol is associated with its ability to inhibit the enzyme cyclooxygenase, as a result of which the metabolism of arachidonic acid and the synthesis of prostaglandins are disrupted. Paracetamol inhibits both cyclooxygenase isoforms - cyclooxygenase-1 and cyclooxygenase-2. The drug reduces the amount of prostaglandins in the tissues of the central nervous system, as a result of which the sensitivity of receptors to chemical stimuli decreases and the intensity of pain sensations decreases. Due to the direct effect on the center of thermoregulation in the hypothalamus, paracetamol has an antipyretic effect. The peripheral effect of the drug is weak, since the drug is inactivated by cellular peroxidases.
Caffeine is an alkaloid derived from tea and coffee beans; in addition, caffeine is synthesized from uric acid and xanthine. The drug has a stimulating effect on the central nervous system, enhances and regulates the processes of excitation in the cerebral cortex. Caffeine increases physical and mental capacity for work, increases the excitability of the respiratory and vasomotor centers. When taking the drug, an increase in heart rate is noted and the intensity of contractions of the heart muscle increases. An increase in blood pressure under the influence of caffeine is noted only in shock and collapse, while caffeine does not significantly affect normal blood pressure. The drug stimulates the function of the endocrine glands. There was a slight decrease in platelet aggregation with the use of caffeine. The mechanism of action of the drug is based on its ability to bind to adenosine receptors in the brain. The binding to the receptors occurs due to the structural similarity of the caffeine and adenosine molecules. Since adenosine leads to a decrease in arousal processes, its substitution with caffeine helps to stimulate the nervous system. However, with prolonged use of the drug, nervous exhaustion may develop.
Chlorpheniramine maleate- a drug of the group of H1-histamine receptor blockers. The drug competitively blocks H1-histamine receptors. The most effective drug is for the prevention and treatment of immediate allergic reactions, in which a large amount of histamine is released from mast cells into the blood. The drug has a lower affinity for H1-histamine receptors than histamine, therefore, when it is used, there is no competitive displacement of histamine from the already formed bonds. Chlorpheniramine is only able to prevent the binding of histamine to receptors. The drug has antihistamine, anticholinergic, sedative and atropine-like effects. Chlorpheniramine helps to normalize vascular permeability, reduce itching, eliminate smooth muscle spasm and other effects caused by histamine. In addition, the drug is a blocker of seretonin and m-cholinergic receptors, has a pronounced sedative effect. The drug has a short-term effect, therefore it must be used during the entire time of the allergen's influence.
Phenylpropanolamine hydrochloride- a drug with adrenomimetic activity. Phenylpropanolamine hydrochloride stimulates the release of norepinephrine into the synaptic cleft, resulting in vasoconstriction in the nasal mucosa. The drug helps to reduce swelling and improve nasal breathing. In addition, phenylpropanolamine hydrochloride reduces phenomena such as congestion of the nasal mucosa, sneezing, lacrimation and rhinorrhea.
All active components of the drug are well absorbed in the gastrointestinal tract after oral administration. The maximum concentration of paracetamol in blood plasma is reached within 30-60 minutes after oral administration, phenylpropanolamine hydrochloride - within 1-2 hours, chlorpheniramine maleate - within 30-60 minutes. Caffeine is evenly distributed in the body, well penetrates the blood-brain barrier. Paracetamol is metabolized in the liver, with the formation of glucuronide, sulfate and cysteine compounds. Caffeine is metabolized in the body by demethylation and oxidation. Phenylpropanolamine is not metabolized in the body. Chlorpheniramine maleate is characterized by the effect of the first passage through the liver. Phenylpropanolamine is excreted from the body unchanged in the urine. The rest of the active substances are excreted mainly in the form of metabolites in the urine, a small part is excreted unchanged. The half-life of paracetamol is about 2 hours, phenylpropanolamine - 3-5 hours, caffeine - 4-5 hours, chlorpheniramine maleate - 1-1.5 hours.
The therapeutic effect of the drug occurs 30 minutes after application and lasts about 12 hours after oral administration.
Indications for use
A drug Coldflu It is used for the symptomatic treatment of acute respiratory diseases of various etiologies (including acute respiratory viral diseases), including respiratory diseases accompanied by rhinitis, swelling of the nasal mucosa, and fever.In addition, the drug is used to treat mild to moderate pain syndrome, including headache and diseases of the ENT organs, which are accompanied by pain syndrome.
Mode of application
Doses of the drug Coldflu and the duration of the course of treatment is determined by the attending physician individually, depending on the nature of the disease and the personal characteristics of the patient.Adults are usually prescribed 1 tablet of the drug 3-4 times a day.
Children over the age of 12 are usually prescribed 1/2 tablet of the drug 3-4 times a day.
The duration of the course of treatment is no more than 7 days.
The tablet is swallowed whole, without chewing or crushing, drinking plenty of water. The tablet can be divided if necessary.
Side effects
A drug Coldflu usually well tolerated by patients, however, the development of such side effects associated with taking Coldflu is possible:From the gastrointestinal tract: nausea, vomiting, anorexia, indigestion, pain and discomfort in the epigastric region, dry mouth.
From the side of the central nervous system: headache, dizziness, drowsiness, disturbed sleep and wakefulness, increased excitability, irritability.
From the hematopoietic system: anemia, thrombocytopenia.
Allergic reactions: skin rash, itching. In patients with hypersensitivity, anaphylactic reactions may develop.
In addition, when using the drug in some patients, the development of accommodation disorders and an increase in intraocular pressure were noted.
In isolated cases, the development of urination disorders was noted.
Contraindications
:Contraindications to the use of the drug Coldflu are: increased individual sensitivity to the components of the drug; pregnancy and lactation, children under the age of 12; severe impaired liver and / or kidney function, arterial hypertension and chronic heart failure; hyperthyroidism, diabetes mellitus, prostate adenoma, which is accompanied by impaired urination; whose work is associated with the control of potentially dangerous mechanisms or driving a car.
Pregnancy
:A drug Coldflu not prescribed during pregnancy. If it is necessary to prescribe the drug during lactation, it is recommended to resolve the issue of stopping breastfeeding.
Interaction with other medicinal products
Drug interaction Coldflu with other drugs due to the properties of its active ingredients, in particular:Paracetamol, with simultaneous use, enhances the effects of anticoagulants, a group of coumarin derivatives, increases the risk of developing liver damage when using drugs with hepatotoxic properties.
With the simultaneous use of atropine, peptidin and other drugs with an antispasmodic effect, increase the time to reach the maximum plasma concentration of paracetamol.
Barbiturates, rifampicin, ethyl alcohol and antiepileptic drugs, when used simultaneously with paracetamol, increase the risk of developing toxic liver damage due to increased breakdown of paracetamol to hepatotoxic compounds.
Inhibitors of microsomal oxidation (cimetidine) reduce the risk of liver damage when using paracetamol.
Caffeine, when used simultaneously, enhances the effects of drugs that stimulate the central nervous system and reduces the effectiveness of hypnotics and narcotic drugs.
Barbiturates, primidone, nicotine, and anticonvulsants increase the metabolism and elimination of caffeine. Ciprofloxacin, disulfiram, norfloxacin, cimetidine, and oral contraceptives increase the concentration of caffeine in the blood. When using high doses of caffeine simultaneously with monoamine oxidase inhibitors, selegiline, procarbazine and furazolidone, the risk of arrhythmia and arterial hypertension increases. The drug increases the toxicity of cardiac glycosides. Caffeine reduces the absorption of calcium ions in the gastrointestinal tract. An increase in the excretion of lithium preparations was noted when used simultaneously with caffeine. With the simultaneous use of caffeine and beta-blockers, a mutual decrease in the effectiveness of these drugs is noted. Chlorpheniramine maleate, when used simultaneously with monoamine oxidase inhibitors and furazolidone, increases the risk of developing hyperpyrexia and hypertensive crisis. The drug is not prescribed simultaneously with calcium chloride, kanamycin sulfate, phenobarbital and norepinephrine. With the simultaneous use of chlorpheniramine maleate with ethyl alcohol, tranquilizers and other agents that depress the central nervous system, an increase in the sedative effect of chlorpheniramine is noted. Phenylpropanolamine, when used simultaneously with monoamine oxidase inhibitors, increases blood pressure and increases the risk of developing a hypertensive crisis. Reserpine reduces the effectiveness of phenylpropanolamine. The simultaneous use of phenylpropanolamine with drugs that stimulate the central nervous system is not recommended, since phenylpropanolamine increases the risk of tremor, arterial hypertension and increased excitability. With the simultaneous use of phenylpropanolamine with beta-blockers, levodopa and digitalis drugs, the risk of arrhythmias increases. When using the drug before inhalation anesthesia, severe arrhythmias may develop after the administration of inhalation drugs for anesthesia.
Overdose
:When taking the drug Coldflu in doses exceeding the recommended, the development of nausea, vomiting, dry mouth, drowsiness, headache is noted. With a further increase in the dose, the development of arrhythmias, arterial hypertension, urinary disorders and thrombocytopenia is possible.
There is no specific antidote. In case of an overdose of the drug, gastric lavage, intake of enterosorbents and symptomatic therapy are indicated. With the development of a headache associated with taking high doses of the drug, further administration of the drug is contraindicated in order to relieve pain.
Hemodialysis and peritoneal dialysis are not effective.
Storage conditions
A drug Coldflu It is recommended to store in a dry place away from direct sunlight at temperatures between 15 and 25 degrees Celsius.Shelf life is 4 years.
Release form
Tablets of 4 in strips, 1 strip in an envelope.Composition
:1 tablet Coldflu contains: paracetamol - 500 mg; caffeine - 30 mg; phenylpropanolamine hydrochloride - 25 mg; chlorpheniramine maleate - 2 mg.
Excipients.
Source: www.piluli.kharkov.ua
main parameters
| Name: | COLDFLU |
Description
- Homeopathic
For relief of symptoms of colds and flu:
- Runny nose
- Sneezing
- Cough
- Body pain
- Chills and nausea
on indications: c To relieve minor cold and flu symptoms such as runny nose, sneezing, flushing, chills, body aches, headache, cough, sore throat / sore throat.
Symptoms
Symptoms
Flu starts very quickly and may include headache, chills, dry cough, body aches, fever, nasal congestion, and sore throat. After infection, symptoms usually begin within 1-4 days. You can spread the flu with others before your symptoms start and up to 3 to 4 days after symptoms start.
The US Centers for Disease Control and Prevention (CDC) estimates that 10-20% of Americans go down with the flu in each flu season. Children are 2 to 3 times more likely than adults to get the flu, and children often spread the virus to other people.
how to treat flu symptoms
Many help relieve flu symptoms:
- Using; flu
- Resting in bed
Drinking clear liquid
Cold & amp; flu pills are easy to take in the unpleasant cold and flu season. This tablet has been designed to dissolve quickly under the tongue. Take it with you wherever you go - no water needed to use cold & flu. They won't get caught!
Common cold symptoms
Sneezing, sore throat / sore throat, runny nose, cough, sneezing, blockage of the nasal passages, swelling of the sinus membranes, headaches, all cold symptoms. It is perhaps the most common disease known to man, with over 200 different types of viruses that can lead to symptoms of the common cold. After infection, symptoms often begin within 2–3 days, and can last 1–2 weeks.
Hand-washing is one of the most effective ways to keep from catching colds. Avoid touching your nose or eyes during cold and flu season. Cough or sneeze into a tissue and discard, and try to avoid those with colds. Cold microbes can survive for up to 3 hours outside the nasal passages on inanimate objects and skin, therefore, the ecological cleanliness of surfaces with the use of disinfectants.
how to treat cold symptoms
- NaturalCare; flu
- Bed rest
- Plenty of pure water
- Gargle with lemon water
- Use zinc
- Take hot baths
Annually, childhood colds are 6-10, adults can average 2-4 and those over 60 often have less than one cold year.
Natural Care, Cold & Flu Away Flu & Cold Formula 60 Tablets:
Application Recommendations
Adults and children over 6 years of age: If symptoms occur, take 2 tablets (put under the tongue) every 4 hours, up to a maximum of 6 tablets per day, or as directed by your healthcare practitioner. Not for use by children under 6 years of age.
Natural Care, Cold & Flu Away Flu & Cold Formula 60 Tablets:
Warnings
Do not use if security seal is broken or missing. If you are pregnant or lactating, ask a doctor before use. Keep out of the reach of children. Do not use this product for more than 10 days (adults) or 5 days (children). Chronic coughing can be a sign of a serious condition. If the cough persists for more than 7 days, usually recurs, or is accompanied by a rash, persistent headaches, fever lasts more than 3 days, or if new symptoms occur, consult your doctor. If the sore throat is severe, persists for more than 2 days, or is accompanied or accompanied by fever, headache, rash, nausea or vomiting, seek medical attention immediately. In case of overdose, get medical help or contact the Poison Control Center right away.
Hello, my constant friends and those who looked at the blog for the first time))
Autumn time - the charm of the eyes and at the same time the problem of all mothers: how to prevent a child from getting sick, and if he is already sick, then how to effectively and quickly cure a cold / sore throat / flu ...
It is especially difficult if the child is very small, most of the drugs are contraindicated for him due to age, and he does not want to stuff chemistry not only with such babies, but also with older children.
A good option is folk methods of treatment, herbs, decoctions, but personally I do not work well with them ... well, not a herbalist, I never)
To rinse your throat with chamomile or sage is yes, and more complex methods of treatment happen that not only do not help, but look as if it does not work out worse (this happened with the treatment of my allergies, I wrote about this in an article that I treated with the help of decoction of a series, and now I can not tolerate this broth))
Although it worked out with Indian onions, he helped, apparently because my mother prepared the tincture for me))
Here's what to do in such cases? For me, the best way out was to use ready-made syrups, powders and drops made by those for whom this is a profession.
I buy them in pharmacies, most of all I respect, as I have already written more than once, the international online store iHerb, where you can buy goods for both beauty and health. If you are not familiar with it yet, then here you can, which have been bought by me more than once. Well, or by tag you can ask.
So, the preface was not the shortest)) I turn to the main thing. Today's article is dedicated to those who are not very strong in traditional methods of treatment, but want to treat their children with safe means.
Just in case, let me remind you that if a child is sick, self-medication should never be done, we go to the doctor who diagnoses, prescribes treatment, and then we accept what the doctor ascribed.
But in addition to or for mild diseases, you can use drugs that are suitable for the prevention and treatment of non-serious diseases, as well as in addition to the main treatment.
So, we are reading about preparations with iHerb for colds and flu for children, for coughs, for throats, and about a medicine for strengthening immunity in children.
I'll start with the "common" medicines - for colds.
These drugs help with the appearance of "all at once" symptoms - cough, runny nose, perspiration, should alleviate the general condition and provide a therapeutic effect. I must say many of them cope with a bang.
1. Hyland "s, 4 Kids Cold" n Cough Day & Night Value Pack
If you are wondering how to treat a cold in a child of 2-3 years old, when at this age many of the drugs are absolutely contraindicated, then pay attention to this drug.
It relieves all symptoms of a cold, coughs, runny nose, nasal congestion, sneezing and eagle pain. It is highly advisable to take at the first sign of an onset cold.
It can be taken at night and in the daytime, the dosage depends on the age of the child, and it is also suitable for adults, but due to the increase in dosage, the purchase of a drug for the treatment of an adult may be economically unprofitable))
Cough remedies for children
- Homeolab USA, Kids Relief, Cough & Cold
A remedy in the form of a cough syrup for children from 2 years of age.
Helps with different types of coughs, both dry and cough with phlegm. As an added bonus, it relieves fever and associated pain. I won't say about fever, but it really does a very good job with a cough.
Despite the fact that the medicine needs to be given often, every 4 hours, it still lasts for a long time, the bottle is large, and the syrup is consumed sparingly.
So if you only have one child at home who doesn't get sick too often, grab the 100ml Kids Relief bottle ($ 7.99).
If there are two or more children or coughs are frequent, buy a 250 ml bottle of Kids Relief, Cough & Cold ($ 9.99).
- Hyland "s, Baby, Cough Syrup
Pay attention to the remedy suitable for very young children who generally find it difficult to imagine what to give for a cold.
It can be used from 6 months, for even younger ones, be sure to consult a doctor before using.
This dry cough remedy for kids does a good job on a simple cold cough.
Do not use it as the only remedy for treatment, it is still a homeopathic remedy, which means it is not as strong as conventional medicines.
Despite such an abundance of medicines, I still wish you do without them 🙂
Name:
Coldflu
Pharmachologic effect:
Coldflu is a combined drug used for the symptomatic treatment of acute respiratory diseases. The drug has antipyretic, anti-allergic, analgesic and anti-inflammatory effects, reduces the symptoms of rhinitis, and has some stimulating effect on the central nervous system. The mechanism of action and pharmacological effects of the drug are due to the properties of its active components.
Paracetamol is a drug of the group of non-steroidal anti-inflammatory drugs, a derivative of paraaminophenol. The mechanism of action of paracetamol is associated with its ability to inhibit the enzyme cyclooxygenase, as a result of which the metabolism of arachidonic acid and the synthesis of prostaglandins are disrupted. Paracetamol inhibits both cyclooxygenase isoforms - cyclooxygenase-1 and cyclooxygenase-2. The drug reduces the amount of prostaglandins in the tissues of the central nervous system, as a result of which the sensitivity of receptors to chemical stimuli decreases and the intensity of pain sensations decreases. Due to the direct effect on the center of thermoregulation in the hypothalamus, paracetamol has an antipyretic effect. The peripheral effect of the drug is weak, since the drug is inactivated by cellular peroxidases.
Caffeine is an alkaloid derived from tea and coffee beans, in addition, caffeine is synthesized from uric acid and xanthine. The drug has a stimulating effect on the central nervous system, enhances and regulates the processes of excitation in the cerebral cortex. Caffeine increases physical and mental capacity for work, increases the excitability of the respiratory and vasomotor centers. When taking the drug, an increase in heart rate is noted and the intensity of contractions of the heart muscle increases. An increase in blood pressure under the influence of caffeine is noted only in shock and collapse, while caffeine does not significantly affect normal blood pressure. The drug stimulates the function of the endocrine glands. There was a slight decrease in platelet aggregation with the use of caffeine. The mechanism of action of the drug is based on its ability to bind to adenosine receptors in the brain. The binding to the receptors occurs due to the structural similarity of the caffeine and adenosine molecules. Since adenosine leads to a decrease in arousal processes, its substitution with caffeine helps to stimulate the nervous system. However, with prolonged use of the drug, nervous exhaustion may develop.
Chlorpheniramine maleate is a drug of the group of H1-histamine receptor blockers. The drug competitively blocks H1-histamine receptors. The most effective drug is for the prevention and treatment of immediate allergic reactions, in which a large amount of histamine is released from mast cells into the blood. The drug has a lower affinity for H1-histamine receptors than histamine, therefore, when it is used, there is no competitive displacement of histamine from the already formed bonds. Chlorpheniramine is only able to prevent the binding of histamine to receptors. The drug has antihistamine, anticholinergic, sedative and atropine-like effects. Chlorpheniramine helps to normalize vascular permeability, reduce itching, eliminate smooth muscle spasm and other effects caused by histamine. In addition, the drug is a blocker of seretonin and m-cholinergic receptors, has a pronounced sedative effect. The drug has a short-term effect, therefore it must be used during the entire time of the allergen's influence.
Phenylpropanolamine hydrochloride is a drug with adrenomimetic activity. Phenylpropanolamine hydrochloride stimulates the release of norepinephrine into the synaptic cleft, resulting in vasoconstriction in the nasal mucosa. The drug helps to reduce swelling and improve nasal breathing. In addition, phenylpropanolamine hydrochloride reduces symptoms such as redness of the nasal mucosa, sneezing, lacrimation and rhinorrhea.
All active components of the drug are well absorbed in the gastrointestinal tract after oral administration. The maximum concentration of paracetamol in blood plasma is reached within 30-60 minutes after oral administration, phenylpropanolamine hydrochloride - within 1-2 hours, chlorpheniramine maleate - within 30-60 minutes. Caffeine is evenly distributed in the body, well penetrates the blood-brain barrier. Paracetamol is metabolized in the liver, with the formation of glucuronide, sulfate and cysteine compounds. Caffeine is metabolized in the body by demethylation and oxidation. Phenylpropanolamine is not metabolized in the body. Chlorpheniramine maleate is characterized by the effect of the first passage through the liver. Phenylpropanolamine is excreted from the body unchanged in the urine. The rest of the active substances are excreted mainly in the form of metabolites in the urine, a small part is excreted unchanged. The half-life of paracetamol is about 2 hours, phenylpropanolamine - 3-5 hours, caffeine - 4-5 hours, chlorpheniramine maleate - 1-1.5 hours.
The therapeutic effect of the drug occurs 30 minutes after application and lasts about 12 hours after oral administration.
Indications for use:
The drug is used for the symptomatic treatment of acute respiratory diseases of various nature (including acute respiratory viral diseases), including respiratory diseases accompanied by rhinitis, swelling of the nasal mucosa, and fever.
In addition, the drug is used to treat mild to moderate pain syndrome, including headache and diseases of the ENT organs, which are accompanied by pain syndrome.
Application method:
Doses of the drug and the duration of the course of treatment are determined by the attending physician individually, depending on the nature of the disease and the personal characteristics of the patient.
Adults are usually prescribed 1 tablet of the drug 3-4 times a day.
Children over the age of 12 are usually prescribed 1/2 tablet of the drug 3-4 times a day.
The duration of the course of treatment is no more than 7 days.
The tablet is swallowed whole, without chewing or crushing, drinking plenty of water. The tablet can be divided if necessary.
Adverse events:
The drug is usually well tolerated by patients, however, the development of such side effects associated with taking Coldflu is possible:
From the gastrointestinal tract: nausea, vomiting, anorexia, indigestion, pain and discomfort in the epigastric region, dry mouth.
From the side of the central nervous system: headache, dizziness, drowsiness, disturbed sleep and wakefulness, increased excitability, irritability.
From the hematopoietic system: anemia, thrombocytopenia.
Allergic reactions: skin rash, itching. In patients with hypersensitivity, anaphylactic reactions may develop.
In addition, when using the drug in some patients, the development of accommodation disorders and an increase in intraocular pressure were noted.
In isolated cases, the development of urination disorders was noted.
Contraindications:
Increased individual sensitivity to the components of the drug.
The drug is not prescribed for women during pregnancy and lactation, as well as for children under the age of 12 years.
The drug is prescribed with caution to patients suffering from severe impaired liver and / or kidney function, arterial hypertension and chronic heart failure.
In addition, care must be taken when prescribing the drug to patients with hyperthyroidism, diabetes mellitus, prostate adenoma, which is accompanied by impaired urination.
During pregnancy:
The drug is not prescribed during pregnancy.
If it is necessary to prescribe the drug during lactation, it is recommended to resolve the issue of stopping breastfeeding.
Interaction with other medicinal products:
The interaction of Coldflu with other drugs is due to the properties of its active ingredients, in particular:
Paracetamol, with simultaneous use, enhances the effects of anticoagulants, a group of coumarin derivatives, increases the risk of developing liver damage when using drugs with hepatotoxic properties.
With the simultaneous use of atropine, peptidin and other drugs with an antispasmodic effect, increase the time to reach the maximum plasma concentration of paracetamol.
Barbiturates, rifampicin, ethyl alcohol and antiepileptic drugs, when used simultaneously with paracetamol, increase the risk of developing toxic liver damage due to increased breakdown of paracetamol to hepatotoxic compounds.
Inhibitors of microsomal oxidation (cimetidine) reduce the risk of liver damage when using paracetamol.
Caffeine, when used simultaneously, enhances the effects of drugs that stimulate the central nervous system and reduces the effectiveness of hypnotics and narcotic drugs.
Barbiturates, primidone, nicotine, and anticonvulsants increase the metabolism and elimination of caffeine.
Ciprofloxacin, disulfiram, norfloxacin, cimetidine, and oral contraceptives increase the concentration of caffeine in the blood.
When using high doses of caffeine simultaneously with monoamine oxidase inhibitors, selegiline, procarbazine and furazolidone, the risk of arrhythmia and arterial hypertension increases. The drug increases the toxicity of cardiac glycosides.
Caffeine reduces the absorption of calcium ions in the gastrointestinal tract.
An increase in the excretion of lithium preparations was noted when used simultaneously with caffeine.
With the simultaneous use of caffeine and beta-blockers, a mutual decrease in the effectiveness of these drugs is noted.
Chlorpheniramine maleate, when used simultaneously with monoamine oxidase inhibitors and furazolidone, increases the risk of developing hyperpyrexia and hypertensive crisis. The drug is not administered concurrently with calcium chloride, kanamycin sulfate, phenobarbital and norepinephrine.
With the simultaneous use of chlorpheniramine maleate with ethyl alcohol, tranquilizers and other agents that depress the central nervous system, an increase in the sedative effect of chlorpheniramine is noted.
Phenylpropanolamine, when used simultaneously with monoamine oxidase inhibitors, increases blood pressure and increases the risk of developing a hypertensive crisis. Reserpine reduces the effectiveness of phenylpropanolamine.
The simultaneous use of phenylpropanolamine with drugs that stimulate the central nervous system is not recommended, since phenylpropanolamine increases the risk of tremor, arterial hypertension and increased excitability.
With the simultaneous use of phenylpropanolamine with beta-blockers, levodopa and digitalis drugs, the risk of arrhythmias increases.
When using the drug before inhalation anesthesia, severe arrhythmias may develop after the administration of inhalation drugs for anesthesia.
Overdose:
When taking the drug in doses exceeding the recommended ones, the development of nausea, vomiting, dry mouth, drowsiness, and headache is noted. With a further increase in the dose, the development of arrhythmias, arterial hypertension, urinary disorders and thrombocytopenia is possible.
There is no specific antidote. In case of an overdose of the drug, gastric lavage, intake of enterosorbents and symptomatic therapy are indicated. With the development of a headache associated with taking high doses of the drug, further administration of the drug is contraindicated in order to relieve pain.
Hemodialysis and peritoneal dialysis are not effective.
Release form of the drug:
Tablets of 4 in strips, 1 strip in an envelope.
Storage conditions:
Shelf life is 4 years.
Synonyms:
Composition:
1 tablet contains:
Paracetamol - 500 mg
Caffeine - 30 mg
Phenylpropanolamine hydrochloride - 25 mg,
Chlorpheniramine maleate - 2 mg
Excipients.
Drugs with a similar action:
Kofol (ointment) (Kofol) Kofol (lozenges) (Kofol) Humer 050 (Humer) Humer 150 / Humer monodose (Humer) Combigripp (syrup) (Combigripp)
Dear doctors!
If you have experience in prescribing this drug to your patients - share the result (leave a comment)! Did this medication help the patient, did any side effects occur during treatment? Your experience will be of interest to both your colleagues and patients.
Dear patients!If you have been prescribed this medication and you have undergone a course of therapy, tell us if it was effective (helped), if there were side effects, what did you like / dislike. Thousands of people search the Internet for reviews of various medications. But only a few leave them. If you do not personally leave a review on this topic, the rest will have nothing to read.
Many thanks!- Natural homeopathic medicine
- May Help Temporarily Relieve Cold and Flu Symptoms
- Does not contain alcohol
- Natural sweet taste
- Has no side effects
- Does not contain sugar
- Doesn't cause drowsiness
- Manufactured to US Homeopathic Pharmacopoeia Standards
- Quality that parents can trust
NatraBio is committed to leading natural health products formulated and manufactured to pharmaceutical standards.
Indication: For the temporary relief of cold and flu symptoms such as nasal congestion, sore throat, nausea and vomiting, sneezing, runny nose, headache and body aches.
Dosage. For children and infants from 4 months, give 0.5 ml under the tongue every 20 minutes until symptoms disappear, then repeat once every 4 hours or as needed. Consult a physician prior to use in children under 4 months of age.
For best results. Before use, you must clean the mouth. After application, it is not recommended to drink, eat or brush your teeth for at least 15 minutes.
Other ingredients
Active: Aconite (aconitum napellus) 3X, 6X, 12X, 30X, echinacea (echinacea angustifolia) 3X, red onion (allium cepa) 6X, eyebright (euphrasia officinalis) 6X, gelsemium (gelsemium sempervirens) 6X, cinquefoil X, candensis (sanguinaria) lungwort (sticta pulmonaria) 6X; Auxiliary: Citric acid, glycerin, purified water, sodium benzoate.
Warnings
Denial of responsibility
iHerb makes every effort to ensure that images and product information are provided in a timely and correct manner. However, sometimes there may be a delay in updating the data. Even in cases where the labeling of the products you received differs from those presented on the site, we guarantee the freshness of the goods. We recommend that you read the instructions for use indicated on the product before using it, and not only rely entirely on the description provided on the iHerb website.
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