Maximum efficiency will be in the treatment of sports injuries, arthritis, bruises. I personally use it for cervical pain.
I apply the ointment with massaging movements, and wrap my neck with a warm scarf, the pain disappears after 20-30 minutes, most often I do it in the evening before going to bed, and in the morning I get up healthy. For me, this drug is like an "ambulance" for severe pain not associated with any joint changes.
Description of the drug
Finalgon, without the slightest exaggeration, can be called a legendary drug. Older people remember how in the "stagnant" years, doctors advised their patients suffering from back and joint pain to get the Finalgon by any means. It was very difficult, because at that time Finalgon entered only the "Kremlin" clinics and was available to the elite.
But those who were lucky enough to receive the coveted tube could fully appreciate the medical advice. Times have changed - today Finalgon is in every pharmacy. Only the ability of the drug to easily relieve sudden back pain and restore the joy of life has not changed.
What explains such properties of Finalgon? The preparation contains two active and synergistically working substances. The first is nicoboxil, a derivative of nicotinic acid, which dilates blood vessels at the site of application of the cream (5 times compared to the initial value!).
The result of this action is not only an increase in skin temperature by 5-8 ° C and a subjective feeling of pleasant warmth in the painful area, but also the elimination of muscle spasm and increased metabolism. All this leads to the fact that the muscles and ligaments become more elastic, which means that they are capable of light movements and more resistant to stress and injury.
The effect of nicoboxil does not end there. Perhaps its most important property is its ability to provide easy penetration of another active component - nonivamide - a derivative of capsaicin (hot pepper) into the deeper layers of the skin. There, nonivamide acts directly on the nerve endings, resulting in rapid pain relief.
What does Finalgon ointment help from? The active components of Finalgon can, on the one hand, independently exert a therapeutic effect, and on the other, their combination makes the combination perfect, since it provides multidirectional and multilevel effects.
And the feeling of gentle warmth so characteristic of Finalgon is only one of the most striking manifestations of its effects.
In addition to the ability to quickly relieve sudden back pain, Finalgon® can be used for arthrosis, trauma, muscle pain, and also as an adjunct therapy for peripheral circulation disorders. As already mentioned, a feature of Finalgon® is the speed of the onset of the effect. The analgesic effect begins to manifest itself after a few minutes, reaching its maximum by the 20-30th minute, and lasts 6-8 hours.
Finalgon is very easy to use. Do not just forget a few important details of its use. Firstly, one must remember that the optimal dose of the drug is an extruded column 0.5 cm in size - no more than a pea. This amount is sufficient to apply the ointment with the applicator to a palm-sized area of the skin.
If this dose is exceeded, instead of a relaxing feeling of warmth, you may get an unpleasant burning sensation. In this case, you should dab the skin with a cotton swab dipped in oil, and next time be more careful.
The second condition for the more effective use of Finalgon is the application or wrapping of a sore spot with a woolen cloth after applying the ointment. You also need to know that accidental contact with the ointment in the eyes or on the mucous membranes can cause an unpleasant burning sensation. Finalgon ointment should not be used on damaged or irritated skin.
And the last thing with regard to the rules of application - after applying the Finalgon ointment, hands should be thoroughly washed with soap and water.
An important feature of Finalgon is its cost-effectiveness - one package contains up to 150 doses. It is also worth noting that Finalgon® is produced by Boehringer Ingelheim, which means the high German quality of the drug.
Since Finalgon ointment quickly eliminates not only sudden back pain, but also other pain symptoms due to a feeling of caring warmth and a direct effect on nerve endings, the drug can be safely attributed to emergency home care.
pharmachologic effect
Finalgon is a topical agent, which is a combination of two vasodilators: nonivamide, a synthetic analogue of capsaicin, and nicoboxil, a derivative of nicotinic acid. The drug belongs to the group of skin irritating agents that cause:
- Local effects: hyperemia, swelling, irritation of sensitive receptors (pain, burning sensation)
- Reflex effects:
- axon reflexes
- reflex irritation of the respiratory and vasomotor centers from any area of the skin, especially from the skin of the face
- stimulation of the hypothalamus-pituitary-adrenal system, increased release of adrenocorticotropic hormone, glucocorticoids
- Humoral effects: the entry into the bloodstream of breakdown products of tissue proteins, histamine and other mediators.
The distracting effect of the drug is based on irritation of areas of the body surface, which is accompanied by a change in the functional state of certain organs. In addition, the influence of irritating substances is carried out on the corresponding organs through trophic reflexes - nervous influences on the metabolism in tissues. The mechanism of the "distracting" action is very complex and not fully understood.
However, it is known that all reflexes from skin receptors, including trophic, the so-called cutane-visceral, are directed mainly to internal organs that receive innervation from the same segment of the spinal cord. For this reason, it is necessary to rationally select the site of application of the irritating agent.
Finalgon's action differs from the mechanism of action of non-steroidal anti-inflammatory drugs that suppress cyclooxygenase and prostaglandin synthesis. The reduction of soft tissue tenderness achieved by the use of irritants is based on the principles described and is widely used in rheumatology and sports medicine.
Irritants are pain relievers and increase the blood supply to the muscle. Improved blood supply leads to muscle relaxation and increased cellular regeneration. This leads to the relief of chronic pain associated with degenerative and inflammatory lesions of the musculoskeletal system. Pains associated with sprains or muscle injuries are also reduced.
Nonivamide is a synthetic analogue of capsaicin and has analgesic properties, which are manifested as a result of the gradual penetration of the active substance into the peripheral nociceptive C-fibers and A-delta nerve fibers upon repeated application of the drug to the skin. Nonivamide has a vasodilating effect, which is accompanied by an intense, prolonged sensation of warmth, due to the stimulation of afferent nerve endings in the skin.
Nicoboxil is a derivative of niacin, which has vasodilating properties with the participation of prostaglandins I2 and E2. The hyperemic effect of nicoboxil (butoxyethyl ester of nicotinic acid) develops faster and is more intense than the hyperemic effect of nonivamide.
Nonivamide and nicoboxil have complementary vasodilating properties, cause flushing of the skin, increase the rate of enzymatic reactions, and activate metabolism.
The appearance of hyperemia and an increase in skin temperature within a few minutes after application indicate the rapid penetration of the active components of the drug into the skin. The action, according to Finalgon instructions for use, manifests itself locally, develops after a few minutes and reaches a maximum after 20-30 minutes.
The analgesic effect of a combination of 0.4% nonivamide and 2.5% nicoboxil was demonstrated in a study of efficacy in patients with acute nonspecific lower back pain.
It was found that in patients who used the drug Finalgon (2 cm of ointment per application up to 3 times / day for 4 days), there was a clinically significant decrease in the intensity of pain in the lower back already 4 hours after the first application; on the last day of treatment, determined individually, there was also a clinically significant reduction in pain. In a clinical study, it was found that pain relief began after 1–2 hours.
Finalgon instructions for use
Finalgon compares favorably with other drugs of local irritating action. It activates metabolism, provides dilation of blood vessels, hyperemia, increased blood flow, increased extensibility of connective tissue and muscles while decreasing muscle tone.
Unlike Finalgon, preparations containing menthol cause a feeling of coldness, combined with minor pain relief. With prolonged use of menovazine, dizziness, general weakness, and a decrease in blood pressure are possible.
Preparations based on bee and snake venom often cause allergic reactions and have many contraindications (for example, acute infectious diseases, tuberculosis, hepatitis, diabetes mellitus, organic diseases of the central nervous system, pregnancy, etc.).
Finalgon is generally well tolerated. In rare cases, allergic skin reactions may occur. It is also not applied to wounds and areas of skin with impaired permeability, to the neck, inner thighs and abdomen.
Indications and contraindications
Finalgon is used for pain in muscles and joints, muscle and ligament injuries, joint inflammation and peripheral circulation disorders. It is highly effective for radiculitis, arthritis, neuralgia. Finalgon ointment acts as an effective irritant and as a thermal patch.
Finalgon is not used in conjunction with other dosage forms for external use.
The ointment is used according to indications:
- Polymyalgia rheumatica is a muscle disorder that causes severe pain in the hips, neck, and shoulders. Caused by inflammation.
- Rheumatic arthralgia is a disease characterized by migratory, severe, persistent pain, mainly in the lower extremities.
- Arthritis is an articular lesion.
- Ligament injuries after injuries, bruises, including sports.
- Myalgia resulting from exercise.
- Neuritis is an inflammatory disease of the nerves, which is accompanied not only by pain, but also by loss of sensitivity of the affected areas.
- Lumbago - acute pain in the lower back.
- Sciatica, sciatica - sharp, aching or excruciating pains localized in one of the limbs or back.
- Tenosynovitis is an inflammation of the tendon synovium.
- Bursitis is an inflammatory, purulent lesion of the periarticular synovial bag.
- Warming up muscle tissue before exercise before exercise, sports competition.
- Peripheral circulatory disorders as part of a combined treatment plan.
- Against prostatitis (rarely and as an untested technique).
- As part of complex vasodilator therapy for peripheral circulatory disorders.
A sensitivity test is recommended before using local warming agents. This will help avoid multiple negative reactions.
Finalgon contraindications. The tool is not used for:
- Identifying unhealthy sensitivity of the treatment site.
- Open wounds.
Areas with an increased permeability factor - inner thigh, neck, lower abdomen, folds of the arms.
Method of administration and dosage
Treatment should be started by applying a small amount of the drug to a small area of the skin to assess the individual response. The individual reaction to the drug can differ significantly: for some people it will be enough to apply a small amount of ointment in order to cause the necessary warming effect.
Using the supplied applicator, a column of preparation no more than 0.5 cm in size is applied to the appropriate area of the skin the size of a palm with light rubbing movements. To enhance the therapeutic effect, the area of the skin to which the drug is applied can be covered with a woolen cloth.
With repeated use, the reaction to the ointment may decrease, which requires an increase in the dose, which is selected individually. If necessary, the ointment is used 2-3 times / day.
For preliminary warming up of muscles before physical exercises, sports competitions it is recommended to rub in about 30 minutes before their start.
The patient should be warned that in the absence of the desired effect within 10 days, consult a doctor. After applying the drug to the skin, wash your hands thoroughly with soap and water.
Overdose
Symptoms: the effect of skin flushing and the severity of dose-dependent side effects may be aggravated after using an excessive amount of Finalgon ointment. The use of excessive amounts of the drug can lead to the formation of vesicles or pustules at the site of application of the ointment.
An overdose of the drug can cause systemic reactions (reddening of the upper body, increased body temperature, “hot flushes” of blood, painful hyperemia, decreased blood pressure). esters of niacin have good transdermal absorption.
Treatment: when using an excessive amount of the drug, the effect can be reduced if the ointment is removed from the skin surface with vegetable oil or an oily cosmetic cream, from the mucous membrane of the eye (in case of accidental contact) - with the help of medical petroleum jelly. If necessary, symptomatic treatment should be carried out.
In case of an overdose of the drug, a side effect such as a burn can be observed. Moreover, due to the unequal sensitivity of the skin in people, different amounts of the drug may become critical.
The skin reacts to an excess of finalgon with sharp redness, swelling, and sometimes the appearance of bubbles with liquid (vesicles or papules). The involvement of a huge number of nerve endings in the process leads to the fact that the victim experiences a severe burning sensation, reaching the sensation of pain or cramps, which can hardly be tolerated.
If the patient did not first consult with the doctor, did not read the instructions when and how to use the drug, but squeezed about a teaspoon of ointment into the palm of his hand and rubbed his knee or cervical region, then a severe burn is almost guaranteed. Having felt at first a pleasant warmth, after 5-10 minutes a person will begin to experience such a burning sensation and pain that he will not find a place for himself.
But there is no need to panic. Every house has some kind of vegetable oil: sunflower, sea buckthorn, olive, linseed. It is one of these oils, and by no means water or alcohol solutions, that must be urgently used to stop the growing pathological phenomena in the skin burned by the finalgon.
This will require pieces of natural fabric or cotton pads. This material is moistened with oil and applied to the excess ointment, then with a wiping motion it is removed and discarded. But some part of the finalgon has already managed to pass the upper layers of the skin.
To get it out, a layer of oil is again applied to the skin and left for a few minutes. Then, with gentle movements of cotton pads or rags, the oil mask is removed. After that, discomfort and burning sensation remain for some time, which soon disappear. By the way, milk can be used instead of butter.
Side effects
In the course of long-term experience with the drug, the following side effects have been identified:
- From the immune system: anaphylactic reactions, hypersensitivity.
- From the nervous system: paresthesia, burning sensation of the skin.
- From the respiratory system: cough, shortness of breath.
- On the part of the skin and subcutaneous tissues: vesicles or pustules at the site of application, local skin reaction (for example, contact dermatitis), itching, rash, swelling of the face, urticaria, a feeling of heat at the site of application.
special instructions
The drug causes flushing of the skin, as a result of which there is redness, a feeling of warmth, itching and burning at the site of application. These symptoms may be more pronounced when an excessive amount of the drug is applied or in the case of intense rubbing on the skin surface. The use of excessive amounts of the drug or vigorous rubbing on the surface of the skin can lead to the formation of vesicles or pustules at the site of application of the ointment.
After using Finalgon, you should immediately wash your hands with soap and water. Care must be taken to avoid accidental contact of the drug on other areas of the skin or contact of the drug on another person.
Avoid accidental contact with face, eyes, nose or mouth. This can lead to temporary facial swelling, facial pain, conjunctival inflammation, redness of the eyes, burning eyes, blurred vision, oral discomfort, and stomatitis.
Influence on the ability to drive vehicles and control mechanisms. Special clinical studies of the effect of the drug on the ability to drive a car and mechanisms have not been conducted. However, during the use of the drug when driving and working with mechanisms, caution should be exercised.
Due to the local flushing of the skin caused by Finalgon, redness, warmth, itching and burning are expected at the site of application. These symptoms can be especially noticeable if the amount of finalgon applied is excessive or if the preparation is rubbed intensively onto the skin surface. Excessive application or rubbing in with Finalgon can cause blisters on the skin.
The patient should be advised that:
- after application with finalgon, hands should be washed immediately with soap in order to avoid contact with other skin areas or transmission to other people;
- Finalgon should not be applied to the face, eyes or oral mucosa. There may be fleeting facial swelling, facial pain, conjunctival irritation, flushing, burning eyes, visual disturbances, oral discomfort and stomatitis;
- Finalgon should not be applied to sensitive skin areas (front of the neck, lower abdomen, inner thighs);
- the skin of people with fair hair and persons with increased sensitivity can usually react more strongly, therefore a warming effect can be achieved even with very low doses of Finalgon;
- patients should not take a hot bath or shower before or after using Finalgon.
Redness of the skin and intense warmth for several hours after application of Finalgon may be caused by perspiration or warming.
Finalgon ointment contains an auxiliary substance - sorbic acid, which can cause a local skin reaction (for example, contact dermatitis).
Drug analogs
Betalgon... Application: a remedy with a distracting, antispasmodic, warming effect. A small amount of the drug is applied to the painful area, the therapeutic effect is achieved after 30 minutes.
Features and differences:
- The use of the product should start with small doses.
- The active ingredients are nicotinic acid butoxyethyl ether and pelargonic acid vanillamide.
- Cost: packaging 20 g - 212 rubles.
"Betanicomilon"... Application: local irritant with local action. The dosage amount is rubbed into the painful area twice a day.
Features and differences:
- The active ingredient is pelargonic acid vanillamide, nicotinic acid butoxyethyl ether.
- For medical purposes, the drug is used in pediatric practice.
- Cost: packaging 20 g - 235 rubles.
"Kapsikam"... Application: a dosed amount of the product (1-3 g) is applied to the affected areas. Features and differences:
- Active ingredients - dimethyl sulfoxide, camphor.
- Cost: package 30 g - 189 rubles.
Doctors recommend using the warming properties of the drug not only for sick people, but also for athletes who experience stress on the musculoskeletal system. Massage rubbing helps to relieve pain after exercise, prevent spasms.
Non-hormonal analgesic anti-inflammatory drug.
Price from 241 rub.
Non-hormonal analgesic anti-inflammatory drug.
Application- joint pain, arthritis.
Analogs- Dolobene, Menovazin, Bee venom. You can find out more about analogues, their prices, and whether they are substitutes at the end of this article.
Today we'll talk about Finalgon ointment. What is the remedy, how does it affect the body? What are the indications and contraindications? How and in what doses is it used? What can be replaced?
What kind of ointment
This remedy has a strong analgesic effect and is used not only to eliminate discomfort on the skin, but also for joint pain.
The effect is due to the special microelements contained in the preparation and causing local irritation. Thus, inflammation is removed and some pain mediators soften and reduce their activity.
Finalgon gel is a fairly well-marketed remedy, it is constantly recommended by doctors, but it does not fight the cause of the disease.
Active ingredient and composition
The medical effect is based on an element officially named nicoboxil, supplemented by nonivamide.
Both are derived from natural alkaloids (alkali, which is extracted from plants), therefore, acting in combination, there is a mild effect that is not able to injure the upper epithelium.
Safety is proven by the fact that in powder form, nonivamide can be used in cooking as a spicy seasoning.
As additional and main components in the composition, there are:
- nicoboxil;
- nonivamide;
- medical petroleum jelly;
- purified water;
- emulsifier;
- natural citronella oil;
- paraffin;
- sorbic acid;
- cromadol.
The effect of most of them is binding, that is, the action of these substances does not bring significant benefits to the body.
However, they are found in small quantities that cannot cause or cause serious reactions from the body.
Pharmacological properties
The action is exerted by influencing the vascular system with the help of a local irritating action.
The effect is similar to medications that belong to the class of analgesics.
The action is carried out quickly enough and lasts several hours. With constant use, there is no addiction or the need to use more gel.
Contact with the eyes must be avoided, as this will cause severe irritation, because the active ingredient is obtained from the pepper.
Pharmacodynamics and pharmacokinetics
The medical effect is achieved using two chemical elements.
1 Nicoboxil. Penetrates deep under the skin and irritates the walls of the vessel, from which they begin to expand and allow more blood to pass through. This allows you to get rid of the constant impact of non-nerve endings, and the pain will be perceived by the brain as much less.
2 Nonivamide, which is a synthetic analogue of capsaicin. Has a pronounced analgesic effect. This is achieved due to the fact that the substance negatively affects some receptors and they temporarily cease to send the necessary information to the brain. In this case, the sensation of pain completely disappears (gradually).
The time required for full penetration is 30 minutes.
Absorption into the bloodstream occurs quickly, but insignificantly. Serious side reactions are possible only on the basis of allergies.
Indications
What is Finalgon used for? Experts recommend it to relieve pain when undergoing the following health problems:
- overexertion of muscle tissue due to excessive exercise;
- myalgia (muscle pain);
- which is caused by groundless non-infectious inflammation of the nerve endings, while it is necessary to clarify the diagnosis, because otherwise the desired effectiveness will not be achieved;
- injuries of joint capsules and ligaments;
- arthralgia;
- and lumbago, which caused the inflammatory response;
- almost all problems arising from sports competitions (sprains, tissue damage).
In some cases, professional athletes use this remedy to warm up their muscles before training or competing. However, continued use can lead to minor side effects.
There are no cheap analogues of Finalgon with the same wide range of applications.
Contraindications
Finalgon's absolute contraindications are.
1 Allergy to at least one of the constituent components, even if it occurs in small quantities and performs a binding role.
2 Hypersensitivity. The verification procedure is simple, for this, rub the required small amount of the contents into the back of the elbow. If there is no burning or itching, then everything is fine.
3 Age less than 12 years old.
4 Pregnancy or breastfeeding.
5 Open bleeding wounds.
It should be noted that if at least one of them is present, then it is necessary to abandon therapy.
Method of use and dosage
At the first admission, it is necessary to check the strength of the action, depending on the individual characteristics of the organism.
For this, the agent is applied in a small amount to the skin. If no painful sensations occur within 15 minutes, then the dosage can be increased.
Using the applicator, rub the ointment into the desired area.
The main advice of doctors is the need to use in the place where the most pain is noticed.
When used topically, the curative effect is in a small area.
In childhood, during pregnancy and hepatitis B
Finalgon is contraindicated during pregnancy.
In case of breastfeeding, it is necessary to transfer the baby to infant formula, or to postpone the treatment for a long time.
Finalgon is a popular remedy for the treatment of various pathologies of the musculoskeletal system.
The active components of the agent have a pronounced local irritant property, have an anti-inflammatory, analgesic, warming and vasodilating effect.
Finalgon is used for the treatment of tendovaginitis, arthritis, bursitis, myalgia and arthralgia, eliminating the effects of bruises and injuries, and also as a means to warm up the joints and muscles of athletes before training or sports.
Redness and an increase in skin temperature after applying the ointment indicate a high rate of drug penetration. The maximum degree of local action of Finalgon is observed 15-30 minutes after application.
Clinical and pharmacological group
A drug with a local irritant and analgesic effect.
Conditions of sale from pharmacies
Can buy without a doctor's prescription.
Price
How much does Finalgon cost in pharmacies? The average price is at the level of 300 rubles.
Composition and form of release
Finalgon is available in the form of an ointment of 30-50 g in an aluminum tube.
- The main active ingredients are nonivamide 4 mg and nicoboxil 25 mg.
Auxiliary components: silicon dioxide, petrolatum, sorbic acid, citronella oil, adipic acid.
Pharmacological effect
Finalgon has analgesic and anti-inflammatory effects. After applying this drug to the skin, the active substances penetrate into the peripheral and nerve fibers. This drug promotes vasodilation and improves enzymatic reactions. Also, Finalgon is able to cause temporary flushing of the skin to improve blood flow.
Reviews of Finalgon say that the drug has the property of deep penetration of active ingredients into tissues. Therefore, its use gives a relatively quick effect, which occurs within 25-30 minutes. It acts on the foci of inflammation in a direct way, eliminating pain. It helps to restore damaged muscles, tissues and nerve fibers of the human body.
Indications for use
What does it help from? Finalgon can be used for the symptomatic treatment of any injuries and pathologies that are accompanied by acute pain. Main indications for use:
- Inflammation of the periarticular bag.
- Sciatica.
- Inflammation of the roots of the spinal cord.
- Tenosynovitis.
- Pain in muscles and joints with rheumatism.
- Inflammation of the joints.
- Muscle pain caused by extreme physical exertion.
- Sprains, bruises, trauma and other damage to the ligaments, provoked by the performance of sports exercises.
- Back pain.
- Neuralgia.
- Inflammation of the nerves.
- Pathology of the peripheral circulation.
- Carrying out a quick "warm-up" of the muscles before exercising.
Contraindications
- hypersensitivity;
- age up to 12 years;
- pregnancy and lactation.
Do not use the ointment on inflamed skin areas, sensitive skin, areas with increased permeability (inner thighs, neck, lower abdomen).
Appointment during pregnancy and lactation
Despite the fact that the active elements of the Finalgon drug practically do not enter the systemic circulation, the use of the drug by pregnant and lactating patients is contraindicated. An exception is the complete refusal of breastfeeding during lactation.
Dosage and method of administration
As indicated in the instructions for use, treatment should be started by applying a small amount of the drug to a small area of the skin to assess the individual response. The individual reaction to the drug can differ significantly: for some people it will be enough to apply a small amount of ointment in order to cause the necessary warming effect, while in others the warming effect is insignificant or absent.
It is necessary to start using the drug with the lowest dose. To do this, using the supplied applicator, a column of the drug no more than 0.5 cm in size is applied to the appropriate area of the skin the size of a palm with light rubbing movements. To enhance the therapeutic effect, the area of the skin to which the drug is applied can be covered with a woolen cloth.
With repeated use, the reaction to the ointment may decrease, which requires an increase in the dose, which is selected individually. The maximum recommended dose of the drug is no more than 1 cm of a column of ointment per palm-sized area (about 10 × 20 cm).
- If necessary, the ointment is used 2-3 times / day.
For preliminary warming up of muscles before physical exercises, sports competitions it is recommended to rub in about 30 minutes before their start.
The patient should be warned that in the absence of the desired effect within 10 days, consult a doctor.
After applying the drug to the skin, wash your hands thoroughly with soap and water.
Adverse Reactions
Finalgon ointment has a limited number of side effects that affect various body systems. The maximum number of side effects develops on the skin:
- vesicles and pustules;
- contact dermatitis;
- rash;
- swelling of the face;
- hives;
- a strong feeling of heat in the area of application.
Side effects not related to the skin are also possible:
- anaphylactic reactions;
- hypersensitivity;
- paresthesia (“running of goose bumps”);
- burning sensation on the skin;
- cough;
- dyspnea.
Overdose
When an excessive amount of Finalgon ointment is applied to the skin, severe hyperemia develops and an intense burning sensation appears, and negative side effects may also occur. Less often, systemic reactions can develop in the form of reddening of the skin of the upper body, a decrease in the level of systemic blood pressure.
Treatment consists in washing off the ointment from the skin, as well as treating it with vegetable oil or a cosmetic cream on an oily basis. If systemic signs of an overdose of Finalgon ointment appear, you should consult a doctor.
special instructions
Before you start using the drug, read the special instructions:
- After using Finalgon, you should immediately wash your hands with soap and water.
- Do not take a hot bath or shower before or after applying the drug to the skin.
- The preparation contains sorbic acid, which can cause local skin irritation (for example, contact dermatitis).
- Care must be taken to avoid accidental contact of the drug on other areas of the skin or contact of the drug on another person.
- The release of sweat or the application of heat to the site of application of the drug can cause reddening of the skin and an intense sensation of warmth even several hours after the application of Finalgon.
- Avoid accidental contact with face, eyes, nose or mouth. This can lead to temporary facial swelling, facial pain, conjunctival inflammation, redness of the eyes, burning eyes, blurred vision, oral discomfort, and stomatitis.
The drug causes flushing of the skin, as a result of which there is redness, a feeling of warmth, itching and burning at the site of application. These symptoms may be more pronounced when an excessive amount of the drug is applied or in the case of intense rubbing on the skin surface. The use of excessive amounts of the drug or vigorous rubbing on the surface of the skin can lead to the formation of vesicles or pustules at the site of application of the ointment.
Compatibility with other drugs
Drug interaction of the drug Finalgon with other drugs used locally or systemically has not been identified.
Few facts about the product:
Instructions for use
Online pharmacy price website: from 335
Pharmacological properties
Composition and form of release
The drug is produced in the form of an ointment, which is packed in special tubes with a volume of 20 or 50 grams. In the kit with the drug, you can find instructions. The following elements are considered the constituent components of the Finalgon:
Indications for use
International Classification of Diseases (ICD-10)
Side effects
Taking medication can cause the manifestation of unwanted side reactions of the body, which are expressed in the following symptomatic signs:
Contraindications
Application during pregnancy
The medication should not be taken during the period of gestation and breastfeeding of the baby, since there is no information about the effect of the medication on the fetus and baby.
Method and features of application
The medication is produced in the form of an ointment and is intended for local external use. The medication is applied to the area of skin requiring therapy. Before using the medication, you should check the body's reaction to it by applying to a small area of the skin and waiting for a short time. Thus, it is necessary to determine the amount of the applied drug in order to achieve an effective effect, as well as to check the risk of allergic reactions. To begin with, the medication is applied in a very thin layer using a special applicator that comes with the product. The ointment is applied in a small layer of half a centimeter to the desired area of the skin. It must be rubbed into the skin until a slight burning sensation appears. Then you can cover the skin with the ointment with a woolen cloth. The dosage varies depending on the disease and the individual susceptibility of the organism. You can use the product up to three times a day. With prolonged use, the medication can be addictive and then the patient will need to increase the dosage. If the drug is used to warm up the skin before physical training, then it should be applied to the skin half an hour before exercise. If Finalgon does not have the desired effect within ten days of continuous use, then you must contact your doctor for an individual selection of the drug. After using the ointment, you must wash your hands well to remove the remnants of the medication. Do not be afraid if, after using the product, a burning sensation, redness or itching of the skin appears. This is a normal reaction of the body to the components of the drug. Due to this effect, the drug penetrates the skin faster and has the desired effect. However, the recommendations for using the medication prescribed in the instructions should not be neglected, as this can cause allergic reactions and skin rashes. It is necessary to apply the medication carefully, not getting on other areas of the skin, on the face, on the mucous membranes. This can lead to swelling, painful sensations, inflammation, burning sensation, blurred vision, and other unpleasant sensations. Do not take a hot shower before or after using the product. The medication does not affect the ability to drive vehicles or perform work that requires maximum concentration of attention, since the drug does not affect the nervous system and the speed of psychomotor reactions.
Interaction with other medications
Finalgon can be used concurrently with other drugs, since it does not affect their pharmacokinetic and pharmacodynamic properties.
Overdose
Excessive application of medication to the skin can cause a number of symptomatic signs to appear:
Analogs
Finalgon has a number of analogues in terms of composition and pharmacological action. The most popular ones are:
Terms of sale
The medication is sold in pharmacies in the public domain, which means that the buyer does not need to receive a prescription sheet from a medical institution or a special prescription from the attending physician.
Storage conditions
It is recommended to store the medication in a place isolated from the reach of children at a temperature not exceeding 25 ° C. Finalgon has a shelf life of four years from the date of manufacture. After the expiration date and storage period, the medication cannot be used and must be disposed of in accordance with sanitary standards and the provisions of the instructions for use.
Finalgon (nonivamide + nicoboxil) is a local irritating external preparation. It is used to relieve pain in joint and muscle pain, back pain, to activate peripheral blood circulation in muscle tissue in preparation for a competition or exercise. Pain accompanies 90% of existing diseases. There is no such person on earth (leaving out the rarest cases of analgesia) who does not experience pain. To eliminate this unpleasant feeling in domestic medicine, Finalgon ointment from Boehringer Ingelheim International (Germany) has been used for several decades. Its active ingredients - nonivamide (a component of hot pepper) and nicoboxil (a derivative of nicotinic acid) - potentiate each other's effects. Nicoboxil acts as a vasodilator, providing nonivamide with optimal conditions for rapid interaction with nerve endings and relief of pain. It should be noted that the composition of Finalgon is unique for the Russian market: there is not a single drug in domestic pharmacies with the same set of active ingredients. In addition to affecting the receptors of nerve fibers, Finalgon acts as a means of heat therapy. When applied to a place where pain is felt, the active components of the drug contribute to a local increase in temperature in the tissues. In this area, the lumen of blood vessels increases, blood flow is activated, muscle spasms are eliminated.
The heat effect is one of the tools for providing an analgesic effect. At the same time, the tissues become more elastic, the volume of movement of the musculoskeletal and articular-ligamentous apparatus increases. After the application of Finalgon, the positive effect develops within 5-7 minutes, and the peak of the ointment action is noted after 20-30 minutes. The total duration of the effect is 6-8 hours. Finalgon is indicated for diseases accompanied by pain, but in the absence of inflammation. This drug is in demand to mitigate the effects of sports injuries and bruises. The drug is included in the combination therapy regimens for circulatory disorders in the capillary bed. The use of Finalgon does not require any specific skills and abilities: the manufacturer puts the applicator in the box with the ointment to ensure the accuracy of squeezing out a single dose. Finalgon is not used on open wounds, scratches, cuts, etc. Redness and an increase in the temperature of the skin at the site of application indicates the rapid absorption of active substances. The drug course begins with a small amount of ointment to assess the patient's tolerance to the drug and determine the most effective and safe dose. The response to a drug can vary significantly from patient to patient. For some, even a small amount of ointment has a pronounced warming effect, while others will need more ointment.
Pharmacology
Nonivamide is a synthetic analogue of capsaicin and has analgesic properties, which are manifested as a result of the gradual penetration of the active substance into the peripheral nociceptive C-fibers and A-delta nerve fibers upon repeated application of the drug to the skin. Nonivamide has a vasodilating effect, which is accompanied by an intense, prolonged sensation of warmth, due to the stimulation of afferent nerve endings in the skin.
Nicoboxil is a derivative of niacin, which has vasodilating properties with the participation of prostaglandins I2 and E2. The hyperemic effect of nicoboxil (butoxyethyl ester of nicotinic acid) develops faster and is more intense than the hyperemic effect of nonivamide.
Combined action
Nonivamide and nicoboxil have complementary vasodilating properties, cause flushing of the skin, increase the rate of enzymatic reactions, and activate metabolism.
The appearance of hyperemia and an increase in skin temperature within a few minutes after application indicate the rapid penetration of the active components of the drug into the skin.
Finalgon's action manifests itself locally, develops after a few minutes and reaches a maximum in 20-30 minutes.
The analgesic effect of a combination of 0.4% nonivamide and 2.5% nicoboxil was demonstrated in a study of efficacy in patients with acute nonspecific lower back pain. It was found that in patients who used Finalgon® (2 cm of ointment per application up to 3 times / day for 4 days), there was a clinically significant decrease in the intensity of pain in the lower back already 4 hours after the first application; on the last day of treatment, determined individually, there was also a clinically significant reduction in pain. In a clinical study, it was found that pain relief began after 1–2 hours.
Pharmacokinetics
Data on the pharmacokinetics of Finalgon® are not available.Release form
Ointment for external use is almost colorless or slightly brownish, transparent or translucent, homogeneous, homogeneous.
Excipients: diisopropyl adipinate (crodamol) - 120 mg, colloidal silicon dioxide - 20 mg, petrolatum (paraffin, soft white) - 822 mg, sorbic acid - 2 mg, citronella oil - 2 mg, purified water - 5 mg.
20 g - aluminum tubes (1) complete with an applicator - cardboard packs.
Dosage
Treatment should be started by applying a small amount of the drug to a small area of the skin to assess the individual response. The individual reaction to the drug can differ significantly: for some people it will be enough to apply a small amount of ointment in order to cause the necessary warming effect, while in others the warming effect is insignificant or absent.
It is necessary to start using the drug with the lowest dose. To do this, using the supplied applicator, a column of the drug no more than 0.5 cm in size is applied to the appropriate area of the skin the size of a palm with light rubbing movements. To enhance the therapeutic effect, the area of the skin to which the drug is applied can be covered with a woolen cloth.
With repeated use, the reaction to the ointment may decrease, which requires an increase in the dose, which is selected individually. The maximum recommended dose of the drug is no more than 1 cm of a column of ointment per palm-sized area (about 10 × 20 cm).
If necessary, the ointment is used 2-3 times / day.
For preliminary warming up of muscles before physical exercises, sports competitions it is recommended to rub in about 30 minutes before their start.
The patient should be warned that in the absence of the desired effect within 10 days, consult a doctor.
After applying the drug to the skin, wash your hands thoroughly with soap and water.
Overdose
Symptoms: the effect of skin flushing and the severity of dose-dependent side effects may be aggravated after using an excessive amount of Finalgon® ointment. The use of excessive amounts of the drug can lead to the formation of vesicles or pustules at the site of application of the ointment.
An overdose of the drug can cause systemic reactions (redness of the upper body, increased body temperature, "hot flashes" of blood, painful hyperemia, decreased blood pressure), because esters of niacin have good transdermal absorption.
Treatment: when using an excessive amount of the drug, the effect can be reduced if the ointment is removed from the skin surface with vegetable oil or an oily cosmetic cream, from the mucous membrane of the eye (in case of accidental contact) - with the help of medical petroleum jelly. If necessary, symptomatic treatment should be carried out.
Interaction
Drug interaction of Finalgon ® with other drugs used locally or systemically has not been identified.
Side effects
In the course of clinical studies and long-term experience with the drug, the following side effects were identified:
From the immune system: anaphylactic reactions, hypersensitivity.
From the nervous system: paresthesia, burning sensation.
From the respiratory system: cough, shortness of breath.
On the part of the skin and subcutaneous tissues: vesicles or pustules at the site of application, erythema, local skin reaction (for example, contact dermatitis), itching, rash, facial edema, urticaria, a feeling of heat at the site of application.
Indications
- arthritis;
- arthralgia and myalgia of rheumatic genesis;
- sports injuries, bruises and damage to the ligamentous apparatus;
- myalgia caused by excessive physical exertion;
- lumbago;
- neuritis;
- sciatica;
- bursitis and tendovaginitis;
- acute nonspecific pain in the lower back;
- for preliminary "warming up" of muscles before physical exercises, sports competitions;
- as part of complex vasodilator therapy for peripheral circulatory disorders.
Contraindications
- children and adolescents up to 18 years of age (due to insufficient data on efficacy and safety for this group of patients);
- hypersensitivity to nicoboxil, nonivamide or excipients of the drug.
The drug should not be applied to sensitive skin, open wounds, inflamed skin areas, skin areas with increased permeability: neck, lower abdomen, inner thighs.
Application features
Application during pregnancy and lactation
There have been no special studies of Finalgon ® in pregnant and lactating women, therefore, the drug should not be prescribed during pregnancy and lactation.
Studies of the effect of the drug on fertility have not been conducted.
Application in children
Contraindicated in children under 12 years of age.special instructions
The drug causes flushing of the skin, as a result of which there is redness, a feeling of warmth, itching and burning at the site of application. These symptoms may be more pronounced when an excessive amount of the drug is applied or in the case of intense rubbing on the skin surface. The use of excessive amounts of the drug or vigorous rubbing on the surface of the skin can lead to the formation of vesicles or pustules at the site of application of the ointment.
After using Finalgon ®, you should immediately wash your hands with soap and water.
Care must be taken to avoid accidental contact of the drug on other areas of the skin or contact of the drug on another person.
Avoid accidental contact with face, eyes, nose or mouth. This can lead to temporary facial swelling, facial pain, conjunctival inflammation, redness of the eyes, burning eyes, blurred vision, oral discomfort, and stomatitis.
Do not take a hot bath or shower before or after applying the drug to the skin.
The release of sweat or the application of heat to the site of application of the drug can cause reddening of the skin and an intense sensation of warmth even several hours after the application of Finalgon.
The preparation contains sorbic acid, which can cause local skin irritation (for example, contact dermatitis).
Influence on the ability to drive vehicles and use mechanisms
Special clinical studies of the effect of the drug on the ability to drive a car and mechanisms have not been conducted. However, during the use of the drug when driving and working with mechanisms, caution should be exercised.
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