Mixed infections of the genital tract in women are quite common; for their treatment, combined means have been created, one of which is Trezhinan. Conditionally pathogenic and pathogenic flora creates a microenvironment comfortable for it, jointly suppressing the natural bacteria of the vagina and efforts to resist each other to antibiotics.
To cope with such a complex infection can only be a multicomponent drug that is able to actively influence the fungal flora, pathogenic bacteria, and eliminate the symptoms of inflammation. Terzhinan describes the instructions for use exactly as such a multi-vector medication. In terms of cost, for a drug of this class, Terzhinan is at an average level. For Terzhinan, the price ranges from 300 to 500 rubles.
General characteristics of the drug
This product is one of the most successful projects in French pharmaceuticals. A drug that has a pronounced antimycotic, antibacterial activity and the qualities of a local anti-inflammatory agent - this is how the instruction describes its qualities on Terzhinan. The composition of the drug ensures its versatility. The main active substances of the medicine are:
- Nystatin, which is able to fight thrush, due to its ability to suppress sterol synthesis and increase the permeability of the fungal cell.
- Ternidazole, which is able to inhibit the growth of Trichomonas and fight microorganisms that grow without oxygen (anaerobes), for example, gardnerella.
- Neomycin is an aminoglycoside that irreversibly destroys the production of protein in the cells of aerobic microorganisms (bacteria that grow only in the presence of oxygen: staphylococcus aureus, corynebacteria).
- Prednisolone is a glucocorticoid that determines the anti-inflammatory properties of the drug, its anti-allergic effect. This substance prevents the formation of exudate and tissue edema.
A huge advantage of the drug is the possibility of its use in the gestational period (from the second trimester it is free, from the first - only if the expected benefit for the expectant mother is so great that the doctor has to neglect the potential harm to the fetus). But it is worth noting that the plus is very conditional. Since the medication is allowed only in the domestic instructions for it.
Many French information sources refer to pregnancy as a contraindication for the use of this medication. Therefore, self-medication with this medication during the gestational period is strongly discouraged, if only because it is better to avoid medications containing hormones during pregnancy. Such a decision can only be made by a qualified specialist.
Forms of issue
This medication is for topical use. The only form of release for this medication is vaginal tablets. Patients often look for Terzhinan candles. This form is currently not provided by pharmaceuticals. The tablets have a faint yellow color interspersed with darker elements. Terzhinan tablets have an oblong shape and are engraved in the form of the letter "T".
Contraindications and side effects
For the treatment of girls under the age of 16, it is considered unacceptable to use the Terzhinan medication with instructions for the use of suppositories - the instruction categorically does not recommend the use of this drug in case of allergy to any of its components.
The active components of the drug, actively affecting the vaginal microflora, sometimes cause a negative local reaction:
- Burning.
- Redness of the mucous membrane.
- Slight itching.
Terzhinan describes the instructions for using a suppository (more precisely, vaginal tablets) as a very mild remedy, which causes the described phenomena much less often than other local remedies. The instruction does not say anything about an overdose of the drug on tablets, which are sometimes looked for, like Terzhinan suppositories. Regarding the interaction with other medicines on Terzhinan candles, the instructions for use do not say anything. It is believed that there is no data to support any effect of these vaginal tablets on the action of other medications.
Terzhinan recommends instructions for using the tablet exclusively for topical use. It is used for therapy:
- genital mix infections (mixed) in the acute period;
- chronic confirmed mycoses;
- for prevention purposes.
Terzhinan tablets instructions for use recommend to enter 1 piece per day. It is better to do this at night, after the usual hygiene procedures. The tablets should be injected as deeply as possible. Before that, it is worth soaking them a little (for 20 seconds) with water. This causes the top layer to melt and take effect almost immediately after the tablet is inserted. It is not worth getting up immediately after its introduction. You need to lie down for at least 20 minutes.
The course of treatment lasts on average 10 days, if the fungal infection is chronic and it is confirmed by research, the course can be doubled. The prophylactic course usually lasts only 6 days.
For tablets or as they are incorrectly called Terzhinan suppositories, indications for use are:
- bacterial mix infections, that is, vaginitis caused by Candida and / or opportunistic bacterial flora;
- trichomoniasis;
- prevention before medical abortion, childbirth, genital surgery, hysteroscopy, diathermocoagulation in the cervical region, and after the installation of intrauterine contraceptives.
Suppositories Terzhinan during pregnancy (more precisely, tablets for intravaginal administration) are allowed from the second trimester of pregnancy in the same dose as outside of gestation.
Having familiarized yourself with what Terzhinan suppositories are: instructions for use, the price of these vaginal tablets is the information that will certainly interest potential customers.
The cost of the drug
When looking for the price of suppositories on Terzhinan, patients face difficulties, because they produce a medicine in vaginal tablets. For Terzhinan candles, the price starts at 300 rubles. The cost of the product depends on the number of tablets in the package and the pharmacy network. For example, from 399 rubles to 463 rubles, this is the price for Terzhinan medication, the price of 10 suppositories is the price for 6 vaginal tablets 320 -340 rubles.
Considering that the drug is complex and effective against a whole spectrum of pathogenic and opportunistic microorganisms, as the instructions for use are described by Terzhinan suppositories, the price of these vaginal tablets is quite acceptable.
Having become interested in Terzhinan instructions on the use of suppositories at the price of a medication, many potential buyers would like to know if it is possible to buy a cheaper medication to replace their prescribed remedy.
Terzhinan - official instructions for use (tablets)
Drugs with a similar action
The pharmaceutical market does not offer structural analogs for Terzhinan. The closest to it in composition is Proliginax, it is distinguished by its antibacterial component, it contains three active components versus four active substances in the described preparation. At the price, Poliginax is slightly cheaper. It costs 6 vaginal capsules about 290-311 rubles.
Other complex topical agents and even vaginal antiseptics are suggested as agents that can replace the described drug. For example, Metromicon-Neo costs about 300-310 rubles or Ginalgin (at a price of 300 rubles). Or monopreparations, for example, Meratin-Kombi, as well as local antiseptics. (Hexinone)
Having studied carefully the instructions on the use of candles on Terzhinan, the price - reviews on this medicine will help determine whether it is worth looking for a cheaper option. But it is worth remembering that doctors warn that when making decisions, the main focus on patient reviews is not entirely reasonable. Since the body and the situation are different for everyone. And the effect, both positive and negative, in a particular patient can be very different from what is written in the reviews.
Review at a glance
In general, the drug receives positive reviews from both doctors and patients. The main complaint noted on Terzhinan by reviews is the body's reaction in the form of burning and itching. If you want to get acquainted with the opinion of those who have already used this medicine, it is better to look not for what kind of suppositories there are on Terzhinan, but what responses the women left on the Terzhinan vaginal tablets. Comparing the instructions for use on Terzhinan the price of a medicine (more precisely, the ratio of cost and effectiveness), most patients are satisfied with this medicine.
According to experts, the drug is very good, and justifies its widespread use in gynecological practice. At Terzhinan price - instructions for use are harmoniously combined. The effectiveness of using the drug will be slightly lower if you forget to soak it in water. Then the process of dissolution and absorption will go slower, and some of the medicine may be removed during morning urination, without having time to "work" properly.
The annotation indicates a minimum of contraindications for the drug and describes only local discomfort as a negative reaction of the body. Nevertheless, on Terzhinan vaginal tablets, which are mistakenly called Terzhinan suppositories: instructions for use, price, reviews, drugs similar in action are described only for informational purposes. Self-medication with this remedy is not recommended.
Video: Woman's intimate health
Suppositories Terzhinan is a combined preparation, which is characterized by the presence of antifungal and bactericidal properties.
Many users ask what Terzhinan candles are, from what they help.
With the help of this medication, you can get rid of anaerobic microorganisms, pyogenic bacteria, fungi, etc.
Due to the presence of a substance called ternidazole in the composition of this drug, it is used to produce a high-quality fight against Trichomonas. When using the drug, anaerobic microorganisms also die.
The destruction of protein synthesis in the cells of pathogenic microorganisms is carried out with the help of neomycin. This also contributes to the fact that the transcription of the genetic code is disrupted.
As a result, microbial cells die. Some people have a question, what are Terzhinan candles made of, what are they from? This medication fully fights against corynebacteria, Staphylococcus aureus, methicillin, listeria. All these microorganisms are classified as anaerobic bacteria.
As a result of the study of suppositories, the sensitivity of gram-negative bacteria to it was noticed. Pseudomonas aeruginosa is among the bacteria that this drug destroys.
Terzhinan is characterized by the presence of nystatin in its composition, which is an antimycotic agent. That is why, when using the drug, there is a binding of nystatin and ergosterol, which is a constituent of the membrane of the fungal cell.
This leads to damage to the shell and to the death of the fungi.
Fungi, which belong to the category of the genus, also show sensitivity to this medication. With the help of Terzhignan, you can fully combat eukaryotes.
Some patients have a question, one hundred such Terzhinan candles, what are they prescribed for? Due to the presence of prenizolone in the composition of the drug, it is characterized by the presence of antiallergic, anti-inflammatory and antiexudative action.
No damage to the vaginal epithelial tissue has been observed while taking this drug. The pharmacokinetics of the drug have not been studied. This is due to the fact that Terzhinan has a low systemic absorption.
Suppositories Terzhinan are characterized by very good absorption, which allows them to be fully used for the treatment of various fungal and bacterial infectious diseases. He will tell you more about Terzhinan in the video:
Reasons for using Terzhinan
Due to the unique composition of this medication, it is used to combat various diseases of the external genital organs of female representatives, which are characterized by an infectious nature.
This medication is prescribed to patients with vaginitis, which occurs as a result of exposure to pyogenic microflora. Also, this drug is prescribed by doctors for recurrent colpitis, which belong to the category of non-specific vaginitis.
For Trichomonas vaginitis and vaginal dysbiosis, Terzhinan is also prescribed. If, as a result of the activity of fungi of the genus Candida, a female representative has vaginitis, then taking this medication is recommended by doctors.
For vaginitis, which are of a mixed nature of origin, Terzhinan can also be used.
The drug is a prophylactic agent that is widely used to prevent the appearance of females, who will subsequently undergo various surgical procedures.
This medication is most often taken before childbirth, abortion. If the patient is prescribed diathermocoagulation, then she needs to use suppositories not only before the procedure, but also after it.
Before conducting a study such as metrosalpinography, this drug is also used.
Terzhinan is used in the event that the patient will be injected with an intrauterine device. In this case, this medication is used not only before the procedure, but also after it. For complications of antibiotic therapy, suppositories can also be used.
Suppositories Terzhinan are a broad-spectrum drug, which allows them to be used to treat various diseases.
Features of taking the drug
This medication is used if patients have:
- Vaganitov
- Vulvovaginitis
- , which are characterized by a non-specific origin.
In order to prevent infections before surgery, childbirth, suppositories are also used. Terginal is characterized by a high level of effectiveness and therefore it is widely used for preventive purposes.
Taking the drug is quite simple. Suppositories must be inserted into the vagina after taking hygiene procedures. This drug is taken within 10 days. At a time, a female representative must be inserted into the vagina one candle at a time.
In order for the candle to soak, it is soaked in water for one minute before being inserted into the vagina. After that, it should dry out a little.
When using this medication for the treatment of thrush, they must be used within 20 days. At the end of the intake of suppositories, three days later, the patient must be re-tested, with the help of which the doctor can determine the effectiveness of the treatment.
The course of taking Te5zhinan candles is determined depending on the type of disease and the individual characteristics of the female.
Treatment of any disease with the help of this medication should not be done on your own, as this can lead to disastrous consequences. In this case, you must initially consult a specialist.
Possibility of side effects and contraindications Terzhinan
Like any other drug, this drug is characterized by the presence of actions. They are very rare. The introduction of this medication is carried out locally.
That is why the absorption of the drug is carried out in the systemic circulation at a very low concentration.
In registered cases of side effects of Terzhinan, the presence of allergic symptoms in the vagina and external genitals is observed. In some cases, female representatives have complained of burning sensation while using this drug.
Tingling sensation may also occur during use. Discomfort for women while using the drug brings itching. During the use of suppositories, female representatives experienced irritation in the pelvic area.
Poor wound healing is a very rare side effect while taking this medication. Atrophy of the mucous membranes of the vagina was observed in isolated cases of taking this medication.
In order to avoid side effects while taking this medication, it is necessary not to take it if there are pronounced contraindications.
Terzhinan is prohibited from taking women who have pronounced allergic reactions.
The use of the drug is carried out by representatives of the female sex, whose age is more than 16 years.
Terzhinan is a versatile medication that is widely used to treat diseases in women. The drug is characterized by ease of use and high impact.
Terzhinan, the instructions for the use of which must be strictly observed, is used in the gynecological field. In the indications for the appointment - vaginitis of various types.
The drug is highly effective.
Terzhinan vaginal tablets are characterized by the following action:
- antibacterial;
- anti-inflammatory;
- antiprotozoal;
- antifungal.
The drug owes its high efficiency to the following components included in its composition:
- Ternidazole. Able to eliminate a number of anaerobic bacteria, including gardnerella.
- Neomycin sulfate. An effective antibiotic with a wide range of effects.
- Nystatin. An antibiotic with high antifungal activity.
- Prednisone. Has anti-inflammatory effect.
In addition to the main ones, auxiliary substances are included in the composition of vaginal suppositories.
The composition of the drug helps to maintain a normal pH in the vagina.
Indications
Indications for the use of Terzhinan suppositories are as follows:
- bacterial vaginosis caused by an infection;
- bacterial inflammation of the vagina;
- vaginal candidiasis (thrush);
- nonspecific vaginitis;
- gardnerellosis;
- vaginitis caused by Trichomonas.
Vaginal suppositories are prescribed in the following cases:
- prophylaxis before surgery;
- prevention of complications after surgery;
- various methods of artificial termination of pregnancy and the period before childbirth;
- use of an IUD (intrauterine device).
The main advantage of using Terzhinan tablets is that they act on pathogenic microorganisms, destroying them, but at the same time do not disrupt the natural microflora of the vagina.
Terzhinan: instructions for use
If Terzhinan tablets are prescribed, the instructions for use must be followed exactly. It is recommended to insert one vaginal tablet or suppository into the vagina once a day, before going to bed. If the drug is used during the daytime, then after the administration of the drug, you need to lie down for about 20 minutes.
For more convenient administration, the tablet should be held in water for about 20 seconds before use.
The duration of treatment is 10-20 days, recommendations are given by the attending doctor. During menstruation, therapy does not stop.
If the drug is prescribed for prophylaxis, then the duration of the treatment course is about 7 days.
During pregnancy
Terzhinan during pregnancy is prohibited for use in the first trimester. On the 2nd and 3rd trimester, admission is possible, but only according to the indications of the attending doctor and under his control.
The use of the drug during breastfeeding is possible if the benefit to the woman significantly outweighs the risk to the child. But only a doctor can decide this question.
Contraindications
Suppositories Terzhinan are contraindicated for admission only if the woman has an individual intolerance to the individual components of the drug.
Side effects
According to reviews, side effects are rare. Women mostly point to local reactions.
The manufacturer indicates the following side effects:
- burning sensation in the vagina;
- irritation;
- symptoms of an allergic reaction.
Price
Pharmacies offer Terzhinan vaginal tablets in packs of 6 pieces and 10 pieces.
Average price:
- packaging of 6 tablets - from 310 rubles;
- package of 10 tablets - from 420 rubles.
Analogs
The following drugs are referred to the analogs of Terzhinan:
- Pimafucin (vaginal suppositories, 6 pieces) - from 250 rubles;
- Polygynax (vaginal capsules, 6 pieces) - from 299 rubles;
- Clotrimazole (vaginal tablets, 6 pieces) - from 12 rubles;
- Meratin Combi (vaginal tablets, 10 pieces) - from 1500 r.
The most effective analogue is Polygynax, which contains three antibiotics. The only disadvantage is its ineffectiveness in the treatment of trichomoniasis.
When treating with Terzhinan vaginosis caused by Trichomonas, parallel treatment of the sexual partner is recommended. During sexual intercourse during therapy, it is necessary to use barrier contraception or completely abandon intimate relationships.
With or candidiasis after completion of the course, it is necessary to pass repeated tests. Full recovery can only be judged if there are appropriate examination results.
The drug should be prescribed only by a doctor. Self-medication is not acceptable. The wrong choice of dosage, insufficient duration of the therapeutic course can lead to complications and the transition of the disease to the chronic stage.
On the video about the drug
Terzhinan is a drug with antibacterial, anti-inflammatory effect, in addition, the drug has an antiprotozoal, antifungal effect. The drug is used locally in gynecology. For readers of "Popularly about health" I will present instructions for the use of this pharmaceutical product.
So, Terzhinan's instruction:
Composition and form of release
Means Terzhinan is produced by the pharmaceutical industry in light-yellow vaginal tablets, they are flat, their shape is oblong, there is a chamfer, and there is also an engraving in the form of "T" on both sides. The active substances of the drug are as follows: ternidazole, prednisolone sodium metasulfobenzoate, neomycin sulfate, and nystatin is also present.
In the composition of Terzhinan there are excipients: wheat starch, magnesium stearate, lactose monohydrate in the required amount, colloidal silicon dioxide, sodium carboxymethyl starch is present.
Pharmacological action Terzhinan
The pharmaceutical preparation Terzhinan is a combined agent, as it contains several active compounds. This tool is used in gynecological practice. The drug has different actions: antimicrobial, antifungal, anti-inflammatory, antiprotozoal, in addition, when introduced into the vagina, it ensures the integrity of the mucous membrane and maintains a constant pH.
One of the active ingredients is ternidazole, an antifungal pharmaceutical agent belonging to the group of imidazole derivatives. This compound reduces the biosynthesis of ergosterol, changes the structure of the cell membrane and its properties, and also has a trichomonacid effect. This component is active against Gardnerella spp., As well as other anaerobic bacteria.
Another active ingredient in vaginal tablets is neomycin, a broad spectrum antibiotic belonging to the aminoglycoside group. It acts bactericidal, that is, it causes the death of pathogenic microorganisms, in particular: Staphylococcus, Shigella boydii, Streptococcus pneumoniae, Escherichia coli, Shigella dysenteriae, as well as Shigella sonnei, in addition, Proteus spp., Shigella flexneri.
The next active substance of the drug is represented by the antifungal antibiotic nystatin, it belongs to the group of polyenes. It is highly effective against Candida fungi, slows down their development, and also helps to change the permeability of cell membranes.
The analogue of hydrocortisone is prednisolone, the hormonal agent has a clear anti-inflammatory effect, has an anti-allergic effect, and this compound also has an anti-exudative effect. Due to the combined action of all the listed active components, Terzhinan is used for the treatment of some gynecological pathology, as well as for prophylaxis.
What Terzhinan treats?
Terzhinan's indications include the therapy of vaginitis, which are caused by bacteria sensitive to the pharmaceutical preparation, including bacterial and mixed vaginitis, with trichomoniasis of the vagina, with inflammation of the vagina, provoked by Candida fungi.
In addition, indications for the use of Terzhinan contain information about its use for prophylactic purposes against vaginitis, as well as urogenital infections before gynecological surgical interventions, before hysterography, before childbirth, before abortion, before installing an intrauterine device.
Contraindications for use
Contraindications Terzhinan refers to hypersensitivity to any compounds of this medication.
Terzhinan application, dosage
The medication Terzhinan is intended for vaginal administration. In this case, it is recommended to insert one tablet deep enough into the vagina, while the woman should be in the supine position. It is better to use the medicine at bedtime.
Before direct administration, the tablet should be held for twenty seconds in warm water, and after the administration of the dosage form, it is important to lie for at least ten minutes. Typically, the therapeutic course lasts ten days, and for prophylactic purposes, the medication is prescribed for six days.
Side effects
Side effects of Terzhinan are possible, which will be expressed in the form of a burning sensation, itching, some irritation in the vaginal area. As for systemic negative manifestations, they will be expressed in the form of allergic reactions.
Overdose of Terzhinan
Due to the low absorption of the medicinal product, the occurrence of an overdose is unlikely. In case of accidental swallowing of tablets, vomiting should be promptly provoked. If then the patient feels unwell, any other symptomatology joins, then it is recommended to seek qualified help from the medical staff.
special instructions
In the case of therapeutic measures for vaginitis, trichomoniasis, it is definitely recommended to carry out the simultaneous treatment of sexual partners. The instructions for use inform that therapy should not be canceled during menstruation.
How to replace Terzhinan?
Currently, Terzhinan vaginal tablets have no analogues.
Conclusion
Before treating with Terzhinan, it is recommended to consult a gynecologist.
Terzhinan - an updated description of the drug, you can read the contraindications, side effects, prices in pharmacies for Terzhinan. Useful reviews about Terzhinan -
Combined preparation for topical use in gynecology.
Drug: TERGINANE
The active substance of the drug:
comb. drug
ATX encoding: G01BA
KFG: A drug with antibacterial, antiprotozoal, antifungal and anti-inflammatory action for local use in gynecology
Registration number: P No. 015129/01
Date of registration: 21.07.08
Owner reg. ID: Laboratoires BOUCHARA-RECORDATI (France)
Vaginal tablets
1 tab.
ternidazole
200 mg
neomycin sulfate
100 mg
nystatin
100 thousand units
prednisone
3 mg
Excipients: corn starch, lactose, anhydrous silicon dioxide, talc, magnesium stearate, sodium lauryl sulfate, povidone, perfume.
6 pcs. - contour cell packaging (1) - cardboard packs.
10 pieces. - contour cell packaging (1) - cardboard packs.
The description of the product is based on the officially approved instructions for use.
Pharmacological action Terzhinan
Combined preparation for topical use in gynecology. The effect of the drug is due to the properties of its constituent components.
Ternidazole - an imidazole derivative - has a trichomonacid effect, is also active against anaerobic bacteria, in particular Gardnerella spp.
Neomycin sulfate is a broad-spectrum antibiotic from the aminoglycoside group.
Nystatin is an antifungal antibiotic from the polyene group, highly active against fungi of the genus Candida.
Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.
The composition of the excipient ensures the integrity of the vaginal mucosa and a constant pH.
Pharmacokinetics of the drug.
Pharmacokinetic studies of Terzhinan have not been conducted due to low systemic absorption.
Indications for use:
Treatment of vaginitis caused by microorganisms sensitive to the drug:
Bacterial vaginosis;
Bacterial vaginitis caused by banal pyogenic or conditionally pathogenic bacillus microflora;
Trichomoniasis of the vagina;
Vaginitis caused by fungi of the genus Candida;
Mixed vaginitis.
Prevention of vaginitis:
Before gynecological operations;
Before childbirth or abortion;
Before and after the installation of the IUD;
Before and after diathermocoagulation of the cervix;
Before hysterography.
Dosage and method of administration of the drug.
Assign 1 vaginal tablet / day before bedtime. The average duration of the course of therapy is 10 days; in the case of confirmed mycosis, it can be increased up to 20 days. Treatment should not be discontinued during menstruation.
Before insertion into the vagina, the tablet should be kept in water for 20-30 seconds.
Side effects of Terzhinan:
Local reactions: rarely - burning sensation, local irritation (especially at the beginning of therapy).
Others: very rarely - allergic reactions.
Contraindications to the drug:
Hypersensitivity to the components of the drug.
Application during pregnancy and lactation.
It is possible to use Terzhinan during pregnancy and lactation (breastfeeding) according to indications.
Special instructions for the use of Terzhinan.
It is necessary to carry out simultaneous treatment of the sexual partner because of the danger of re-infection.
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