Dentamet- an effective antimicrobial complex that affects the main pathogenic microflora of the oral cavity, which is the main cause of the development of the inflammatory process
Due to the adhesive properties of its gel base, Dentamet is securely fixed in the lesion focus, which provides a long-term therapeutic effect.
The effectiveness of the drug is due to the presence of two antibacterial components in its composition:
Metronidazole has antibacterial action against anaerobic bacteria that cause periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.
Chlorhexidine is a broad spectrum antiseptic that has a bactericidal effect against vegetative forms of gram-negative and gram-positive microorganisms, as well as yeast, dermatophytes and lipophilic viruses.
Indications for use:
Dentamet intended for the treatment of infectious and inflammatory diseases of the periodontal and oral mucosa:
- acute and chronic gingivitis;
- Acute necrotizing ulcerative gingivitis of Vincent;
- acute and chronic periodontitis;
- youthful periodontitis;
- periodontal disease complicated by gingivitis;
- aphthous stomatitis;
- cheilitis;
- inflammation of the oral mucosa when wearing prostheses;
- postextraction alveolitis (inflammation of the hole after tooth extraction);
- periodontitis, periodontal abscess (as part of combination therapy).
Mode of application:
Dentamet applied topically, for dental use only.
Adults and children over 6 years of age with gum disease (gingivitis) Dentamet is applied to the gum area 2 times a day, it is not recommended to wash off the gel. The duration of the course of treatment is on average 7-10 days. After applying the gel, you should refrain from drinking and eating for 30 minutes.
In case of periodontitis after removing dental deposits, periodontal pockets are treated with Dentamet gel and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease.
In the future, the patient can apply the gel independently: Dentamet is applied to the gum area 2 times a day for 7-10 days.
With aphthous stomatitis, Dentamet is applied to the affected area of the oral mucosa 2 times a day for 7-10 days.
To prevent exacerbations of chronic gingivitis and periodontitis, Dentamet gel is applied to the gum area 2 times a day for 7-10 days. Preventive treatment courses are carried out 2-3 times a year.
To prevent post-extraction alveolitis after tooth extraction, the hole is treated with Dentamet gel, then the gel is applied on an outpatient basis 2-3 times a day for 7-10 days.
Side effects:
When applied topically gel Dentamet the risk of developing systemic side effects is small, but sometimes headache, allergic reactions (skin rash, itching, urticaria) may occur.
Contraindications:
Contraindications to the use of the gel Dentamet are: individual intolerance to metronidazole and other derivatives of nitroimidazole, chlorhexidine; intolerance to any components that make up the drug; children under 6 years of age.
Interaction with other medicinal products:
When applied topically in the recommended doses of systemic interaction of the gel Dentamet with other drugs has not been identified.
Overdose:
Cases of drug overdose Dentamet when applied topically, it was not observed.
Storage conditions:
In a dry, dark place at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Release form:
Dentamet - dental gel.
In an aluminum tube 10 or 25 g.
Structure:
100 g of the drug Dentamet contains active substances: metronidazole 1 g, chlorhexidine gluconate 20% solution 0.5 g.
Excipients (adhesive gel base): menthol 0.25 g, glycerin (glycerol) 5g, propylene glycol 5g, thermostable triethanolamine 0.47g, Arespol 1.25 g, soluble saccharin 0.25 g, purified water 86.28 g.
Composition and release form of the drug
10 g - tubes (1) - cardboard packs.
25 g - tubes (1) - cardboard packs.
pharmachologic effect
Combined drug for topical use.
Metronidazole- a derivative of nitroimidazole, which has antiprotozoal and antibacterial action against anaerobic protozoa and anaerobic bacteria, causing: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Epp.
Inactive against aerobic bacteria.
The mechanism of action consists in the biochemical reduction of the 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of the cell of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.
- disinfectant, active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It acts on bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of the dissociation of chlorhexidine salt in a physiological environment) with negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, has a bacteriostatic effect; at high concentrations, the cytoplasmic content of the bacterial cell is deposited, which ultimately leads to the death of bacteria.
Indications
Acute gingivitis; Vincent's acute necrotizing ulcerative gingivitis; chronic edematous gingivitis; chronic hyperplastic gingivitis; chronic atrophic (desquamative) gingivitis; chronic periodontitis; periodontal abscess; recurrent aphthous (ulcerative) stomatitis; gangrenous pulpitis; post-extraction alveolitis; juvenile periodontitis; toothache of infectious origin.
Contraindications
Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives); children under 6 years of age.
With care: pregnancy, lactation.
Dosage
For dental use only.
Locally, after thorough brushing of the teeth, apply to the gums and interdental spaces. Apply 2 times / day.
For the purpose of prevention, a small amount is added to the toothpaste.
Side effects
Local reactions:"metallic" taste in the mouth.
Systemic reactions:, allergic reactions (skin rash, itching, urticaria).
Drug interactions
Enhances the anticoagulant effect warfarin(an increase in the time of prothrombin formation).
Simultaneous use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.
The antimicrobial activity of metronidazole decreases with simultaneous use with and phenytoin due to the accelerated metabolism of metronidazole.
Cimetidine inhibits the metabolism of metronidazole, which can lead to an increase in the concentration of metronidazole in the blood serum.
special instructions
The use of the drug does not replace hygienic cleaning of the teeth, therefore, during the course of treatment with the drug, tooth cleaning should be continued. However, you should not combine the application of the gel at the same time with the toothpaste.
Avoid contact with eyes.
Pregnancy and lactation
During lactation, if it is necessary to prescribe the drug, it is necessary to decide on the termination of breastfeeding.
Childhood use
Contraindication- children under 6 years of age.
Instructions for use
Dentamet instructions for use
Dosage form
Structure
Dental gel 1 g
Metronidazole 10 mg
Chlorhexidine bigluconate (20% solution) 5 mg
Pharmacodynamics
Combined antimicrobial drug. The effectiveness of the drug is due to the presence in its composition of such active ingredients as metronidazole and chlorhexidine.
Metronidazole is a nitroimidazole derivative with antiprotozoal and antibacterial action against anaerobic protozoa and anaerobic bacteria that cause periodontitis: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusobacterium Borealis, Borealis spp. ...
Inactive against aerobic bacteria.
The mechanism of action consists in the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of the cell of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.
Chlorhexidine is a disinfectant, active against a wide range of vegetative forms of gram-negative and gram-positive microorganisms, yeast, dermatophytes and lipophilic viruses. It acts on bacterial spores only at elevated temperatures. The bactericidal effect is due to the binding of cations (the result of the dissociation of chlorhexidine salt in a physiological environment) with negatively charged walls of bacterial cells and extramicrobial complexes. In low concentrations, disrupting the osmotic balance of bacterial cells and the release of potassium and phosphorus ions from them, has a bacteriostatic effect; at high concentrations, the cytoplasmic content of the bacterial cell is deposited, which ultimately leads to the death of bacteria.
Side effects
"Metallic" taste in the mouth, headache, allergic reactions (skin rash, itching, urticaria).
Selling features
Available without a prescription
Special conditions
Avoid contact with eyes.
Indications
Acute gingivitis;
Vincent's acute necrotizing ulcerative gingivitis;
Chronic edematous gingivitis;
Chronic hyperplastic gingivitis;
Chronic atrophic (desquamative) gingivitis;
Chronic periodontitis;
Periodontal abscess
Recurrent aphthous (ulcerative) stomatitis;
Gangrenous pulpitis;
Post-extraction alveolitis;
Juvenile periodontitis;
Toothache of infectious origin.
Contraindications
Hypersensitivity (including to metronidazole, chlorhexidine and nitroimidazole derivatives).
Enhances the anticoagulant effect of warfarin (an increase in the time of prothrombin formation).
Concomitant use with disulfiram increases toxicity, which can lead to the development of neurological symptoms.
The antimicrobial activity of metronidazole is reduced when used simultaneously with phenobarbital and phenytoin due to the accelerated metabolism of metronidazole.
Cimetidine inhibits the metabolism of metronidazole, which can lead to an increase in the concentration of metronidazole in the blood serum.
Drug interactions
Avoid contact with eyes.
The use of the drug in pregnant and lactating women is undesirable.
Prices for Dentamet in other cities
Buy Dentamet,Dentamet in St. Petersburg,Dentamet in Novosibirsk,Dentamet in Yekaterinburg,Dentamet in Nizhny Novgorod,Dentamet in Kazan,Dentamet in Chelyabinsk,Dentamet in Omsk,Dentamet in Samara,Dental gel dentamet is one of the most effective antimicrobial agents affecting the main pathogenic microflora in the mouth. This article provides detailed instructions for the use of this medication and its analogues.
General characteristics of the dental product Dentamet
Dentamet refers to medicines with antimicrobial properties, used to treat inflammations of infectious etiology. The drug is produced in the form of a gel of uniform consistency of white color with a slightly yellow tint.
The drug contains metronidazole- the main active ingredient of the gel is chlorhexidine bigluconate.
Additional components of the medicine consist of:
- Glycerol (distilled glycerin).
- Sodium saccharinate dihydrate.
- Levomenthol (L-Menthol).
- Propylene glycol.
- Carbomer.
- Trolamine (thermostable triethanolamine).
- Purified water.
The gel is available in tubes of ten or twenty-five grams. The tubes are packed in cardboard boxes. It is widely used only in dentistry.
Dentamet in the form of a gel belongs to the group of combined antimicrobial drugs. The high effect of treatment is achieved thanks to metronidazole and chlorhexidine, which are part of the drug.
Metronidazole is a nitroimidazole derivative that has an antiprotozoal and antimicrobial effect on anaerobic unicellular organisms and a group of prokaryotes that provoke the development of periodontal inflammation. Has no effect on aerobic prokaryotic microorganisms.
Chlorhexidine belongs to disinfecting medicines. It is a drug with a wide range of effects and is highly active. Destructively affects or suppresses the vital activity of gram-negative and gram-positive microbes, yeast-like fungi, viruses. Destroys bacterial spores only during the period of hyperthermia.
In what situations is a medication prescribed
Dental gel dentamet is prescribed in the presence of symptoms:
- Acute gingivitis.
- Vincent's acute necrotizing ulcerative gingivitis.
- Chronic gum disease.
- Chronic hyperplastic gingivitis.
- Gum atrophy.
- Chronic apical periodontitis.
- Periodontal disease, which was complicated by gingivitis.
- Cavities in periodontal tissues filled with pus.
- Recurrent aphthous (ulcerative) stomatitis.
- Gangrenous pulpitis.
- Post-extraction alveolitis.
- Heilita.
- Prepurbentate periodontitis.
- Pain syndrome caused by infection.
- Inflammatory process of the gums, provoked by the presence of prosthetic structures in the mouth.
Information! The prescription of the drug should be carried out exclusively by a doctor based on diagnostic results.
Instructions for use
You can apply the gel not only with a brush, but also with your finger (always with clean hands).
The medication is used only by dentists for application topically to the affected area of the gums. The rules for the procedure are as follows:
- Carry out good dental hygiene.
- Prepare a solution using baking soda.
- Rinse your mouth with it.
- Dry the mucous membranes of the gums well with a gauze pad.
- Squeeze the gel, the size of a small pea, onto a toothbrush.
- Using a brush, spread the gel over the periodontium and the distance between the teeth.
- Do not eat or drink water for thirty minutes after applying the dentamet.
- The frequency of use of the gel is twice a day.
- The duration of therapeutic treatment is recommended up to one and a half weeks.
For the purpose of prevention, an ointment is used after extraction of a dental unit, aggravation of chronic periodontitis and gingivitis. To do this, squeeze a drop of dentamet into the paste and brush your teeth in the morning and evening for thirty days in a row. It is necessary to repeat preventive measures every six months.
Use of the gel in pediatrics, during pregnancy and lactation
The drug is prescribed for children upon reaching the age of six. It is prescribed by dentists for gingivitis and ulcerative stomatitis. It is applied only topically. The gel is applied to the affected area in the morning and in the evening. They hold it for half an hour, and then they are allowed to rinse the mouth, drink and eat. On average, gel treatment lasts seven to ten days.
During gel treatment, hygienic tooth cleaning should not be canceled. Experts do not recommend using the drug during gestation and during breastfeeding.
Important! Self-appointment of denture to children and during the period of gestation of an intrauterine fetus contributes to the formation of irreversible consequences.
Contraindications and side effects
The drug is contraindicated for:
- Individual intolerance to one or more components of dentamet.
- Not recommended for children under the age of six. This is associated with insufficient study of the safe and effective effect of the drug on the child's body.
- Not prescribed for pregnant women, especially in the first three months.
- Breastfeeding is also a contraindication.
- When using the gel, side effects are possible, which are manifested by the following symptoms:
- Metallic taste in the mouth.
- Vertigo and headache.
- Dermatological eruptions.
- Burning sensation.
- The manifestation of a nettle rash.
Attention should be paid to the negative effects of the gel getting into the eyes.
How does the gel interact with other medicines
Increases the anticoagulant effect of warfarin. Applying disulfiram and dentamet simultaneously, it is possible that the toxic picture may increase, which can provoke the development of neurological symptoms.
The antibacterial activity of metronidazole decreases when phenobarbital and phenytoin are taken simultaneously, due to the increased metabolism of metronidazole.
If the gel is applied externally and cimetidine is used as directed during this period, the metronidazole metabolism will decrease, which leads to an increase in the level of metronidazole in the blood serum.
Attention! When prescribing a dental gel, it is recommended to tell your doctor about taking any medications. This approach will allow you to achieve the maximum therapeutic effect and avoid the development of side effects.
Expiration date, storage and dispensing conditions
To store the drug, you must adhere to the following conditions:
- Observe the temperature regime (no more than twenty-five degrees)
- Do not freeze.
- Be sure to store in original packaging and with instructions for use.
- The drug should be kept in a closed cabinet to avoid direct sunlight and children.
- Observe the expiration dates written on the packaging.
- Do not use the drug after the expiration date.
The medication can be purchased in the pharmacy network without a doctor's prescription. The price ranges from 105 to 115 rubles.
Analogs and prices
Dentament has a number of similar drugs with similar pharmacological effects. Among them, experts distinguish:
| Drug name | Description | The cost |
| Metrodent | A drug with antimicrobial and antiseptic properties with lemon, pineapple, strawberry scent. Dental gel is prescribed topically for both treatment and prevention of dental diseases. Metronidazole and chlorhexidine are the main active ingredients of the drug. It is prescribed for adults and children over the age of sixteen. | from 130.00 to 135.00 rubles |
| Metrohex | Complex antimicrobial medicine. It has antiprotozoal and antibacterial effects. The drug has a detrimental effect on unicellular organisms and anaerobic bacteria. Metrohex has no effect on aerobic microorganisms. The main active components of the gel are metronidazole and chlorhexidine. It is indicated for infectious and inflammatory diseases of the oral mucosa in adults and children from 16 years of age. The use of this dental product is prohibited during pregnancy and lactation. The use is contraindicated in case of individual intolerance to metronidazole, chlorhexidine and nitroimidazole derivatives. | From 223.00 rubles |
| Metrozol Denta | Dental antimicrobial gel. Affects the vital functions of unicellular organisms and bacteria. The drug consists of metronidazole, chlorhexidine and excipients. The medicine is prescribed for many forms of gingivitis, chronic stage periodantitis, aphthous stomatitis, gangrenous pulpitis and other dental ailments provoked by an infectious infection. The drug is indicated for pregnancy and lactation. | From 225.00 rubles |
Important! When choosing a similar medicine, Dentament should carefully consider its main components and contraindications. It is strictly forbidden to change the drug on your own.
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