Livarol- is a universal fugnicidal drug, which is prescribed for the prevention and treatment of a number of diseases provoked by the ingestion of pathogenic microbes, bacteria and fungi.
It is the development and reproduction of these microorganisms that is one of the reasons for the onset of inflammatory processes in the pelvic organs.
The use of vaginal suppositories for urogenital candidiasis is a common practice and helps to get rid of the disease in record time and reduce the risk of transmitting candidal fungus to a sexual partner to a minimum.
Positive results of treatment with Livarol suppositories were recorded both in the initial and in later forms of urogenital diseases.
Composition of Livarol candles
The active ingredient of the drug Livarol is ketoconazole, which has a fairly high level of toxicity.
But when using vaginal suppositories, the percentage of penetration of this substance into the blood is small and practically does not appear on the general functioning of the body.
In addition, Livarol contains such excipients as: butylhydroxyanise, polyethylene oxide 1500 and polyethylene oxide 400.
Description of the drug
Livarol candles Is an antifungal and antimicrobial drug, the effect of which is directed specifically at the infected parts of the mucous membrane of the vagina and vulva.
Release form
The medication Livarol is available in so-called suppositories for vaginal use.
The outline packaging of the drug contains 5 pieces of cone-shaped candles of white, pinkish or yellowish color. There are 1-2 contour packs in a cardboard box. The form of selling the medicine depends on the place of sale: it is possible both in contour packages and in cardboard ones.
Properties and action of Livarol candles
- The action of the drug is aimed at suppressing the processes of vital activity and reproduction of pathogens, which are the causative agents of thrush and other diseases of the reproductive system.
- The components of the drug have a negative effect on pathogens, while not causing disruptions in the functioning of the beneficial microflora of the body.
- Livarol has a depressing effect on the vital activity of staphylococci and streptococci, the functioning of which is the root cause of the onset of inflammation of the pelvic organs.
- The use of suppositories can provide a full effect on all foci of inflammatory processes, at the same time and will give a chance to avoid the need to use more drugs to eliminate problems.
- Since the localization of the action of Livarol covers all organs of the small pelvis, the scale of possible treatment and prevention of the onset of inflammatory processes is quite impressive.
Indications for use
Before starting treatment, it is necessary to determine with certainty whether this drug is suitable for your case.
This can be done by highlighting a number of indications for which treatment with Livarol is recommended:
- Prevention of fungal gynecological infections associated with a decrease in the defense of the immune system;
- Candidiasis (vulva and vagina, other urogenital organs);
- Inguinal epidermophytosis;
- Dermatophytosis;
- Treatment of mild and progressive forms of thrush;
- Blastomycosis;
- Sporotrichosis;
- Paracoccidioidomycosis;
- The need to maintain the body after antimicrobial therapy, in case of problems in the biocenotic connections of the vaginal microflora;
- Urogenital dysbiosis;
- Histoplasmosis;
- The emergence and reproduction of fungal infections, which was triggered by an increase in the activity of streptococci and staphylococci.
Mode of application
- It is better to enter suppositories in the evening a few hours before bedtime.
- The introduction of suppositories into the body is made after preliminary removal of the contour packaging in the supine position. Suppositories should be inserted into the vagina forward with a sharp end.
- After that, it is recommended to spend an hour or an hour and a half in bed so that the components of the medication have time to dissolve and penetrate into the mucous membrane of the genitals.
- During the initial stage of thrush, which is accompanied by slight pain and an unpleasant burning sensation when urinating, the drug is recommended to be used for one to three days.
- In the chronic form, therapy will take ten days.
It is possible to determine the progression of the chronic form of candidiasis by a number of symptoms such as:
- Feeling of severe itching in the groin area;
- Observation of swelling of the external genitals;
- Painful sensations in the lower abdomen;
- The appearance of a discharge of a curdled consistency with an unpleasant sour smell.
Application during pregnancy and lactation
The use of Livarol in the first trimester (first twelve weeks) of pregnancy is prohibited.
Even a small fraction of the ketoconazole substance that enters the bloodstream can have an undesirable toxic effect on the formation and subsequent development of the fetus in the prenatal period.
As a result of this, malfunctions and mutational changes in the embryo may occur, followed by the formation of a number of serious complications and diseases of the unborn child.
The use of suppositories in the subsequent months of pregnancy should be strictly coordinated with the attending physician, but even in this case, the use of Livarol should not be long-term.
During pregnancy, there is a high risk of side effects and exacerbation of allergic reactions. The use of the drug during lactation also needs to be taken with precautions.
The use of candles for more than five to seven days is strictly prohibited.
If this period is exceeded, a number of unpleasant symptoms may appear for both the mother and the child. Possible manifestation of an allergy that will negatively affect the chemical composition of milk.
With constant use of the drug, there is a possibility of absorption of the active component into milk, followed by its transfer to the child, which is not desirable.
Childhood use
Since the effect of the constituent components of the drug on the body of a child under 12 years old has not been studied, Livarol is not prescribed for children under 12 years old, since it is not known what the effect on the child's body will be.
The effectiveness and safety of Livarol's influence in this case remains unknown.
Prescribing the drug to children aged 12 to 15 years is made in accordance with medical indicators. Only a doctor can prescribe the application. Self-medication at this age is unacceptable and dangerous.
Contraindications
Contraindications for use in gynecology can be absolute or relative.
Absolute contraindications:
Relative contraindications:
- In the 2nd - 3rd trimester of gestation, candles can be used only as prescribed by the attending physician. The negative effect of the medication on the condition of the fetus during this period is minimized, but with its systematic and long-term use, there is a likelihood of allergic reactions in the mother, which can adversely affect the well-being of the child;
- During lactation allergies may occur with a subsequent effect on the level of milk quality;
- If there are open wounds or ulcers in the vaginal area use should be extremely careful. Ideally, it is recommended to use vaginal tablets only after the wounds have healed. Otherwise, there is a likelihood of pathogenic infections entering the body at the time of administration of the suppository. It is also likely that the amount of ketoconazole entering the bloodstream is exceeded.
Dosage
The dosage of the medicine depends on the degree of complexity of the disease, its form and stage:
- Most often, treatment is carried out, with the frequency of entering one candle per day., within 3 - 4 days.
- The exception is clinical forms of diseases., in this case, the course of therapy is 10 days with the frequency of the introduction of one suppository per day.
- In case of acute vaginal candidiasis or thrush, it is recommended to use one suppository per day for 5 days. The dosage of the active substance should be 400 mg per candle.
- For chronic or recurrent yeast infections it is recommended to introduce one candle at a time. The course of therapy is ten days.
- Preventive therapy for thrush is 5 days during which it is recommended to introduce one suppository per day.
The beginning of the course of treatment or prophylaxis is possible the next day after the end of menstruation. During menstruation, the use of suppositories is undesirable, since the active components of the drug are withdrawn along with the blood and the positive effect of the treatment is reduced to nothing.
If the need arises, the course of treatment can be repeated monthly, subject to prior consultation with a gynecologist.
Overdose
There is no information on an overdose of the drug Livarol, since the percentage of penetration of toxic substances into the body is minimal. The amount of components entering the body is too small to cause an overdose.
Side effects
A large number of positive reviews of women about the action of the drug Livarol are a vivid confirmation of its effectiveness.
According to statistics, vaginal suppositories showed the best results in 97% of treatment examples.
Extremely safe and easy-to-use drug rarely caused side effects.
But doctors warn about the possibility of occurrence, in rare cases, of problems such as:
If one of the listed problems occurs, it is recommended to immediately seek help from a doctor in order to find a lighter analogue of the drug.
Analogs
On the domestic market, there are a number of more sparing analogues of Livarol:
- Sebozol,
- Fluomisin,
- Nizoral,
- Clotrimazole,
- Ginesol and others.
Fluomisin
Clotrimazole
Nizoral
Interaction with other medicinal products
During experimental official testing of the drug's compatibility with other medicines, no acute adverse reactions were found. Incompatibility is minimized due to the reduced ability of ketoconazole to dissolve in the blood.
Therefore, the concurrent use of any other medicinal products is not prohibited. Ketonazole is not transferred through the circulatory system and cannot actively interact with other drugs.
The only exceptions are drugs containing alcohol. Interaction with ethyl has a number of serious consequences.
Interaction with alcohol
Drinking alcohol during treatment is highly undesirable.
The combination of even a small amount of the active components of Livarol that penetrate the body and alcohol can cause disulfiram reactions, which include:
- A sharp decrease in blood pressure;
- Increased heart rate;
- Dizziness followed by fainting;
- Redness of the skin.
In addition, there is a serious risk of liver damage from toxic substances.
The combination of the constituent components of the drug and alcohol increases the level of sulfonylurea production with the subsequent development of hypoglycemia.
In addition, it has a depressing effect of corticotropin on the adrenal glands with the necessary stimulating effect, increases the level of phenytoin toxicity, lowers the acidity of gastric juice and increases the plasma content of digoxin, methylprednisolone, indirect coagulants and other substances.
special instructions
The use of suppositories of the drug obliges you to comply with a number of special instructions:
Treatment of thrush with vaginal suppositories with antifungal components gives the greatest effect and allows you to achieve a quick result. You can buy these drugs in a pharmacy without a prescription, but it is advisable to consult a doctor before using Livarol suppositories: why they are prescribed, how to take, whether it is possible, if necessary, to be replaced with analogues.
Suppositories "Livarol" contain ketoconazole as an active ingredient. This is a substance with a fairly wide spectrum of action, including against fungi and bacteria. Ketoconazole is a component of many antifungal drugs and is most effective as a topical agent against fungus.
Additional substances (base for suppositories) make the treatment much more effective:
- give shape and facilitate the introduction of a candle into the vagina;
- reduce the intensity of inflammation;
- soften the mucous membrane;
- promote healing of minor injuries.
Suppositories give only a local effect for fungal inflammation of the vagina and labia, but are ineffective against fungal cystitis and more serious diseases. Nevertheless, in this case, they can also be used in complex therapy.
Indications for use
Candles from thrush Livarol are prescribed for the following pathologies:
- With vulvovaginal candidiasis (inflammation of the walls of the vagina and the skin of the labia). In this case, they are the main treatment for the disease.
- For candidal cystitis and endometritis, suppositories are prescribed as part of complex therapy along with systemic drugs.
- Can be used to prevent candidiasis with long-term treatment with antibiotics or glucocorticosteroids.
- In chronic and recurrent candidiasis, suppositories are used to relieve exacerbation. In this case, the drug is an element of complex therapy, since the fight against fungus in the vaginal area is not enough.
Also "Livarol" can be used as a prophylactic agent for candidiasis in other areas of the body to prevent the spread of infection to the genitals.
Contraindications
Suppositories "Livarol" can not be used if hypersensitivity to the components of the drug or to the active substance is detected.
Stop taking and consult a doctor when the following signs appear:
- the discomfort;
- pain in the genital area;
- swelling;
- deterioration in general health.
Features and limitations of use
Overdose of "Livarol" in clinical trials was not noted. There are indications that with the introduction of several suppositories in a row, discomfort occurs in the vaginal area, and a severe allergic reaction is possible. These phenomena go away on their own and rather quickly.
The use of suppositories in girls under 12 years of age is not recommended. There is no reliable data on the danger or safety of such treatment. Prescribing "Livarol" to children is possible only if there is laboratory confirmation of the diagnosis of genital tract candidiasis.
In no case should the drug be used in girls without a doctor's prescription.
conclusions
Candles "Livarol" for thrush is an effective remedy, but it is important to strictly follow the instructions and prescriptions of the doctor. If this is not done, then their use may not only fail, but also lead to the exact opposite effect - relapses and chronicity of the disease.
Olga:I had a chronic thrush - you just have to eat sweets, take antibiotics or make love with my husband and again these terrible symptoms! The doctors prescribed different pills, which were of no use. Oh, how much I tried everything - it helped, but not for long. Finally, I was cured, strengthened my immune system, and all thanks to this article... Six months have passed since the last relapse. Anyone who has thrush - I recommend reading it!
Suppositories Livarol is an antifungal drug from the group of imidazole dioxolane derivatives for topical use.
It has a fungicidal and fungistatic effect, the mechanism of which is to inhibit the biosynthesis of ergosterol and change the lipid composition of the fungal membrane.
Active against dermatophytes (Trichophyton spp., Epidermophyton floccosum, Microsporum spp.) And yeast (Candida spp., Pityrosporum spp.). Active against Staphylococcus spp. and Streptococcus spp.
Livarol is effective in acute vulvovaginal candidiasis (thrush), as well as in the recurrent form. When inserted, the candle quickly dissolves from the effects of body temperature and envelops the vaginal mucosa, due to which the ketoconazole is evenly distributed and clears the mucous membrane from the action of fungi.
Indications for use
What does Livarol help from? According to the instructions, the drug is prescribed in the following cases:
- treatment of acute or recurrent forms of vaginal candidiasis (thrush);
- prevention of fungal infections of the female reproductive system caused by a decrease in the body's resistance;
- the period after taking antibacterial and other drugs that can destroy the natural microflora of the vagina.
Instructions for use of Livarol, dosages
Before use, suppositories should be released from the contour package. A vaginal suppository is inserted deep into the vagina while lying on your back.
Standard dosages of Livarol according to the instructions:
- with thrush 1 candle \ 1 time per day (in the evening), the course is not less than 10 days.
- another - 1 candle per day for 3-5 days, depending on the course of the disease.
Side effects
The instruction warns of the possibility of developing the following side effects when prescribing Livarol suppositories:
- hyperemia and irritation of the vaginal mucosa, itching of the vagina;
- rarely - hyperemia and pain in the penis in a sexual partner.
- skin rash, urticaria.
- rarely - toothache, abdominal pain.
Contraindications
It is contraindicated to prescribe Livarol suppositories in the following cases:
- I trimester of pregnancy;
- hypersensitivity to the components of the drug.
The drug should be prescribed with caution in the II and III trimesters of pregnancy, during lactation, for children under 12 years of age.
Overdose
There are no data on overdose.
Interaction
When used with other drugs, no undesirable interactions were noted due to the low resorption capacity of ketoconazole.
Analogues of Livarol, price in pharmacies
If necessary, you can replace Livarol suppositories with an analogue in terms of clinical and therapeutic effect - these are drugs:
- Ketoconazole,
- Mikanisal.
by ATX code:
- Ketoconazole.
When choosing analogs, it is important to understand that the instructions for the use of Livarol, the price and reviews for drugs of a similar action do not apply. It is important to consult a doctor and not make your own replacement of the drug.
Price in Russian pharmacies: Livarol 400mg candles 5pcs. - from 431 to 537 rubles, vaginal suppositories 400 mg 10 pcs. - from 645 to 682 rubles, according to 591 pharmacies.
The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ° C. The shelf life is 2 years. Terms of dispensing from pharmacies - without a prescription.
Treatment of thrush with Livarol candles - what do the reviews say?
Many women who used the drug report that they were able to successfully get rid of thrush with the help of Livarol suppositories. Various stages and forms of the disease are described, but the treatment has always been effective.
On average, the therapeutic course is 5-10 days. Women recommend using the drug at night, as discharge is possible after suppositories, when they dissolve. To stop them, you can use a hygienic swab.
From the point of view of doctors, then, as clinical practice shows, if a patient is faced with thrush, relapses of this disease are almost inevitable. Careful monitoring of the state of the vaginal microflora will allow them to be avoided. The main reasons for the appearance of thrush are long-term use of potent antibiotics, as well as a sharp decrease in immune defense.
No less often, sexual partners who have not undergone simultaneous treatment are infected with candidiasis - this is very important to do! It is also necessary to pass tests to be sure of a positive outcome of treatment, and not be guided only by the disappearance of the symptoms of thrush.
The drug Livarol is available only in the form of vaginal suppositories. The active substances that make up Livarol act directly on the vaginal mucosa and vulva. The substance, acting locally, does not penetrate the bloodstream. Livarol has an additional function - antibacterial, which is effective in the treatment of fungal and bacterial infections, as well as streptococcus and staphylococcus. The base of the suppository dissolves in the vagina and is evenly distributed along all the walls of the cavity, therefore the active substance covers the entire area affected by the fungus. At the same time, the mucous membrane is cleared of harmful liquid.
Release form and composition
The main active ingredient is ketoconazole, in one suppository it is contained in an amount of 400 mg. Each candle is sealed in a contour cell, in one package they can contain 5 or 10 units. For ease of introduction, they have a torpedo shape.
Additional substances are used to distribute the suppository over the vagina and accelerate the penetration of substances into the lesion.
What effect does the drug have
The main target is a fungus of the genus Candida. The drug is also prescribed to combat other fungi that are sensitive to ketoconazole. Among them are yeast fungi and dermatophytes (pityrospores, microspores, trichophytes, epidermophytes).
Ketoconazole stops the growth and development of fungi due to changes in the lipid composition of cell membranes and inhibition of ergosterol biosynthesis. This action is called fungicidal.
Indications for the use of the drug
Treatment with Livarol is effective for the following diseases:
- acute stage of thrush or mycosis;
- chronic stage of thrush or mycosis;
- fungal infection with the addition of streptococcus or staphylococcus;
- prevention of the formation of vaginal candidiasis with hypothermia, taking antibiotics and other factors that lower immunity;
- violation of the normal microflora of the vagina with the risk of candidiasis.
Instructions for use
The drug is injected as deep as possible into the vagina, the woman should be in the supine position. The duration of treatment is determined by the doctor depending on the tests and the clinical picture of the disease.
If the patient has an acute stage of the disease, the course lasts up to 5 days; to combat chronic pathologies, the course is extended to 10 days. Enough introduction of 1 candle per day.
How to use vaginal suppositories:
- Print the outline packaging using special wings.
- Lie on your back, insert a candle with your hands.
- Repeat the procedure every evening without interruption. With an independent interruption of the course, even in the absence of symptoms, there is a risk of the disease turning into a chronic stage.
- If you have a permanent sexual partner, he should also undergo a course of candidiasis treatment using a cream or ointment.
Features of admission during pregnancy
The instructions specify that Livarol should be used with caution during pregnancy. Despite the fact that the active ingredients do not penetrate into the blood, there is a risk of their impact on the development of the fetus. Therefore, the use of suppositories in the first trimeter of pregnancy is prohibited. Studies have shown that the substance ketoconazole has a negative effect on the synthesis of sex hormones in the fetus, which can lead to unformed sexual characteristics in the unborn child.
On the 2nd and 3rd trimeter, Livarol is used after consulting a doctor. The dosage and duration of the course of treatment are not reduced.
Features of taking during lactation
Livarol is also used with caution during lactation. Since the drug does not penetrate the bloodstream, and, accordingly, into breast milk, doctors often prescribe these suppositories to lactating women.
Application features for children
A contraindication for the use of Livarol suppositories is the age of up to 12 years. It should also be remembered that this dosage form can damage the hymen.
Can I have sex during treatment?
It is not forbidden to have sex during treatment, however, there are some caveats. Sexual intercourse should take place before the introduction of the candle. If this happened within the first two hours after administration, then the active substance can negatively affect the condition of the partner's penis. The second point is the removal of the substance from the vagina by a mechanical member, as well as due to the increased activity of the mucous membranes. Thus, treatment may be ineffective, and the disease may become chronic.
Livarol is not compatible with latex drugs, so sex should take place without condoms or contraceptive diaphragms. Otherwise, it is better to postpone intercourse until the end of treatment.
Special instructions for taking candles
Livarol is not used during menstruation. This is not prohibited, however, the result of treatment may be negative, it is better to wait until the end of the cycle or replace the suppositories with pills. Part of the drug may come out with the discharge, which will lead to incomplete recovery and relapse.
Side effects of the drug
The list of adverse reactions is small, they are extremely rare and manifest in the form of allergic reactions. Among them:
- rashes on the skin;
- hives;
- burning;
- redness;
- hyperemia of the vaginal mucosa.
If you do not stop taking the medicine, dizziness, nausea, and unnatural discharge for this period may develop. As a solution to the problem, the doctor selects suppositories with a different active substance.
Contraindications for admission
You should refuse to take Livarol if you are allergic to ketoconazole or if you have an individual intolerance to other additional components of the composition. Suppositories are not prescribed for children under 12 years of age, in the first trimester of pregnancy.
An absolute contraindication is the presence of open wounds in the vagina. This will not only allow the ketoconazole to enter the general circulation, but it will also help spread the infection.
Is an overdose possible?
If you follow the instructions, then the dosage is excluded. If you introduce more than two suppositories at once, then there is a risk of side effects, which can be eliminated by canceling the drug. It is a mistake to believe that you can get rid of unpleasant symptoms faster by increasing the dose of the drug.
Interaction with other medications
If you take Livarol (ketoconazole) and isoniazids or rifampicin at the same time, then the effect of the former is reduced by a decrease in plasma concentration. If you take ketoconazole and cyclosporine, methylprednisolone or indirect anticoagulants, then the concentration of the latter in plasma increases.
Terms and conditions for storing candles
Suppositories are stored in sealed containers in a dry, dark place. Maximum storage temperature 25 ° C, shelf life 2 years.
Drug analogs
List of drugs that contain ketoconazole:
- Ketodine;
- Ketoconazole;
- Livangin-M;
- Ketoconazole-Pharmex;
- Dermazole.
You can replace Livarol with an analogue after consultation and examination with a doctor.
Suppositories Livarol is an effective antifungal drug designed to treat thrush and other infections of the genital tract in women. The Russian-made drug is produced in a convenient form, in the form of vaginal suppositories. The medication is especially popular with women due to the minimum of contraindications. It practically does not cause adverse reactions and quickly cope with the unpleasant symptoms of vaginal candidiasis. We will learn more about the new tool, and get acquainted in detail with the instructions for using Livarol candles.
Livarol –
an antifungal agent for topical use. The drug belongs to the group of imidazole dioxolane derivatives and has a pronounced therapeutic effect directly on the mucous membranes of the vagina and vulva. The active ingredient of Livarol is ketoconazole, which exhibits both fungistatic and fungicidal effects.
The principle of action of ketoconazal is based on inhibition of the synthesis of ergosterol, which is necessary for fungal cells to form the cell membrane. Such a cell wall of the fungus consists of 5-6 layers formed by phospholipids and triglycerides and well protects the microorganism from external influences.
Under the action of the active substance, the lipid composition of the fungal membrane changes, it is destroyed and the microorganism dies. And since the synthesis of ergosterol, which is necessary to create a cell wall, stops, further multiplication of pathogenic fungi does not occur.
Ketoconazole is active against most strains of dermatophytes and yeasts (especially the genus Candida), as well as against staphylococcal and streptococcal microflora. Thus, the drug has two therapeutic effects at once: antimycotic and antibacterial.
When applied topically, the active substance is practically not absorbed into the bloodstream, does not cause systemic side reactions and does not have a negative effect on the body.
The therapeutic effect of Livarol is determined by its polyethylene oxide base, due to which the candle in the vagina quickly dissolves under the influence of body temperature and envelops its walls. In this case, the active substance (ketoconazole) is evenly distributed over the mucous membrane and cleanses it of pathological exudate.
Composition and form of release
Livarol for thrush is produced in the form of vaginal torpedo-shaped suppositories of white color, with a yellowish, creamy or gray tint. Slight marbling on the surface of the candles is considered acceptable. The composition of 1 candle contains 400 mg of the active ingredient (ketoconazole) + auxiliary ingredients that make up its base (macrogol, butylhydroxyanisole).
The package with the drug contains one or two blisters, each of which contains 5 suppositories. The shelf life of the drug is 24 months, it is stored in a dry place inaccessible to children.
The drug is used for the prevention and treatment of fungal infections of the female genital area and is prescribed for the following indications:
For prophylactic purposes, the drug is prescribed to prevent fungal infections during long-term treatment with antibacterial drugs or other medications that disrupt the normal vaginal microflora. Another indication for use is a decrease in immunity after a prolonged infectious disease, which can cause the development of candidiasis.
Since the drug acts only at the local level and is practically not absorbed into the blood, it is not capable of causing systemic reactions, therefore it has a minimum of contraindications. These include:
- first trimester of pregnancy;
- hypersensitivity and individual intolerance to the components of the drug.
Livarol during pregnancy is prescribed with extreme caution in the 2nd and 3rd trimester, strictly according to indications. Treatment takes place under the supervision of a physician. The same requirements are observed during breastfeeding and when prescribing the drug in childhood (up to 12 years).
According to the instructions for the use of the medication, Livarol is prescribed for acute and chronic vaginal candidiasis, which is manifested by the appearance of white cheesy discharge from the vagina and is accompanied by sensations of itching and burning.
Before use as directed, the suppository is released from the contour packaging and inserted into the vagina as deep as possible, taking the position "lying on the back". To achieve a therapeutic effect, it is enough to use the drug once a day for 3-5 days. It all depends on the severity of the symptoms and the general condition of the woman. In chronic candidiasis, Livarol should be used once a day for 10 days. It is best to do the procedure at night and after the introduction of the candle, do not get up again.
Livarol is a completely safe drug that is well tolerated by patients. But in some cases, the following adverse reactions may develop:
- redness and inflammation of the vaginal mucosa;
- burning and itching sensation;
- allergic manifestations in the intimate area as urticaria (rash, hyperemia, swelling).
In very rare cases, a woman may experience manifestations such as dizziness or nausea. When the above conditions appear, you should consult a doctor and decide on the possibility of further use of the drug.
Fungal infections of the vagina are dangerous not only for a pregnant woman, but also for an unborn child. Intensive reproduction of pathogenic fungal or bacterial microflora can provoke intrauterine infection of the fetus, earlier discharge of amniotic fluid, cause infections of the birth canal and premature birth. In this light, it is very important to carry out correct and adequate treatment of vaginal infections during pregnancy.
The attending gynecologist should select the necessary medications and determine the course of treatment, taking into account the clinical picture of the disease, the severity of symptoms and possible contraindications. It should be borne in mind that it is prohibited to use the drug in the 1st trimester.
The doctor may prescribe treatment with Livarol in the 2nd or 3rd trimester of pregnancy. In this case, the medication cannot in any way affect the development of the fetus and, subject to all medical recommendations, is able to quickly cope with the infection.
The main advantage of Livarol is the speed of action. A woman notices a pronounced therapeutic effect after the first application. Discomfort (itching, burning, irritation) disappears, curdled vaginal discharge disappears.
Another advantage of the drug is safety. The active substance Livarol does not penetrate into the circulatory system and cannot have a negative effect on the internal organs and systems of the body, which is especially important when it is prescribed during pregnancy.
The active ingredient, ketoconazole, exhibits not only antifungal effect, but also successfully attacks pathogenic bacteria, acting as an antibiotic. Thus, the drug exhibits a double therapeutic effect and successfully fights not only fungal, but also bacterial microflora.
With the development of an acute form of candidiasis, unpleasant symptoms (discharge, itching, burning) disappear within a short time with the timely appointment of adequate treatment. In the chronic form of the disease, the disease can recur with relapses up to 4 times a year. Moreover, an exacerbation of the disease can be provoked by factors such as overwork, stressful situations or colds.
Experts warn that it is impossible to interrupt the course of treatment, it must be completed. Even after the disappearance of all symptoms of infection, the drug should be used for the period recommended by the doctor. This will avoid repeated relapses of the disease and prevent its transition to the chronic stage.
To avoid a repeated exacerbation of the disease, both sexual partners must be treated at the same time. For the entire period of treatment, it is recommended to refrain from sexual intercourse, not to use barrier contraception, since the drug can negatively affect its effectiveness.
Additionally, a woman is advised to wear their cotton underwear and pay attention to her diet. Preference should be given to a dairy-plant diet, eat more fresh vegetables and fruits and give up sweets and starchy foods, since these products have a negative effect on the composition of the microflora and pH of the vagina. If liquid discharge appears during treatment, you should use panty liners.
Women who are faced with vaginal candidiasis should understand that a relapse of thrush can happen at any time. This can be affected by banal hypothermia, a change in contraceptive or sexual partner. Therefore, it is necessary to monitor the condition of the genital area and pay special attention to the microflora of the vagina.
If repeated relapses occur, it is imperative to undergo a course of treatment under the supervision of a specialist and take a smear during and after therapy. This will help you determine if the medication prescribed by your doctor is right for you and, if necessary, to replace it, will allow you to choose the most effective remedy.
The average price of Livarol in the pharmacy chain ranges from 410 to 460 rubles per pack. Since the cost of the medication is quite high, many patients ask the doctor to choose cheaper analogues.
The question of replacing the drug should be decided by a specialist, one should not select analogs on his own, this can lead to unpredictable consequences and cause unwanted complications.
Structural analogues of Livarol include the following drugs:
- Ketoconazole;
- Mycozoral;
- Nizoral;
- Sebozol.
Other medicines with a similar therapeutic effect are Ornisid suppositories, Flagin, Candide, Sertaconazole. From this list of drugs, the doctor can choose a cheaper analogue.
Numerous reviews of Livarol confirm the high effectiveness of the drug. So, according to statistics, after undergoing a full course of treatment, recovery from thrush was recorded in 97% of cases. The drug is quite safe, easy to use and rarely provokes side effects, for which it enjoys well-deserved popularity among women. Patients recommend using the medication at night, since after dissolving the suppositories, vaginal discharge may appear.
There are practically no negative reviews of Livarol, only in isolated cases women complain of repeated relapses of the disease, but such cases are associated with premature interruption of the course of treatment, or refusal of the sexual partner from simultaneous treatment.
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