Excipients: silicon colloidal dioxide - 1 mg, magnesium stearate - 2 mg, K90 - 4 mg, sodium carboxymethyl stroke (type A) - 6 mg, talc - 6 mg, corn starch - 56 mg, monohydrate lactose - 105 mg.
Film shell composition: Iron oxide red - 0.012 mg, silicon colloidal dioxide - 0.088 mg, titanium dioxide - 0.288 mg, macrogol 6000 - 0.499 mg, sepilm 003 - 6.613 mg (Macroogol-40 Stearat (type I) - 8-12%, microcrystalline cellulose - 35 -45%, hypimosellos - 45-55%).
14 pcs. - Blisters (2) - packs cardboard.
Tablets covered with film shell Dark pink, convex, with engraving "F40" on one side; On a white or almost white ished.
| 1 tab. | |
| famotidin | 40 mg |
Auxiliary substances: silicon colloidal dioxide - 1 mg, magnesium stearate - 2 mg, povidone K90 - 4 mg, sodium carboxymethyl starch (type A) - 6 mg, talc - 6 mg, corn starch - 51 mg, monohydrate lactose - 90 mg.
Film shell composition: Iron oxide red - 0.024 mg, silicon colloidal dioxide - 0.088 mg, titanium dioxide - 0.276 mg, macrogol 6000 - 0.499 mg, sepilm 003 - 6.613 mg (macrogol-40 Stearate (type I) - 8-12%, microcrystalline cellulose - 35 -45%, hypimosellos - 45-55%).
14 pcs. - Blister (1) - packs cardboard.
pharmachologic effect
Gistamine H 2-receptor blocker. Suppresses the secretion of hydrochloric acid, basal and stimulated with gastinium, histamine and acetylcholine, while the pH of the contents of the stomach increases and the activity of pepsin is reduced.
Famotidine poorly affects liver microsomal enzymes.
After receiving the drug inside the action occurs after 1 hour, the maximum of action is within 3 hours after the reception, the duration of the effect ranges from 12-24 hours, depending on the dose.
Pharmacokinetics
Suction
Absorption is incomplete. C MAX is achieved after 1-3 hours and is 0.07-0.1 mg / l. Bioavailability - 40-45%, increases with simultaneous reception Food and decreases with simultaneous reception.
Distribution
Binding with plasma proteins is 10-20%. Penetrates the placental barrier and through the BC. Stands out with breast milk.
Metabolism
30-35% of the drug is metabolized in the liver with the formation of S-oxide.
Election
T 1/2 of is 2.3-3.5 hours. After taking inside, 30-35% of Famotidine is derived by the kidneys unchanged.
Pharmacokinetics in special clinical cases
With QK<10 мл/мин T 1/2 может достигать 20 ч (требуется коррекция дозы).
Indications
- ulcerative duel and stomach and stomach in the exacerbation phase, recurrence prevention;
- treatment and prevention of symptomatic ulcers of the stomach and duodenum (associated with the reception of NSAIDs, stressful, postoperative ulcers);
- erosive gastroduodenitis;
- Functional dyspepsia associated with an increased secretory function of the stomach;
- Reflux Ezophagitis;
- Zollinger-Ellison syndrome;
- prevention of recurrence of bleeding from the upper gastrointestinal departments;
- Prevention of aspiration of gastric juice with general anesthesia (Mendelssohn syndrome).
Contraindications
- pregnancy;
- lactation period;
- childhood;
- Increased sensitivity to Famotidin and other histamine H 2-receptor blockers.
Carefully: Renal or liver failure, liver cirrhosis with portoystene encephalopathy as a history.
Dosage
Take inside.
For ulcerative disease of the stomach and duodenum in the aggravation phase Quamatels are prescribed at a dose of 40 mg 1 time / day before bedtime or 20 mg 2 times / day. If necessary, the daily dose can be increased to 80-160 mg. The duration of treatment is 4-8 weeks.
With the aim of prevention of aggravation of ulcerative diseases of the stomach and duodenum Quamatels are prescribed at a dose of 20 mg 1 time / day before bedtime.
For reflux Ezophagitis The initial dose is 20 mg 2 times / day; If necessary, the drug can be used by 40 mg 2 times / day.
For syndrome Zlinger Ellison The initial dose is 20-40 mg every 6 hours; If necessary, the daily dose can be increased to 240-480 mg.
For prevention of gravity of gastric juiceduring the general anesthesia, the quamatel is prescribed at a dose of 40 mg on the eve of the operation or in the morning per day of operation.
For renal failure if KK<30 мл/мин or creatinine content of serum\u003e 3 mg / dlThe daily dose should be reduced to 20 mg or increase the interval between taking to 36-48 hours.
Side effects
From the digestive system: dry mouth, nausea, vomiting, decreased appetite; Improving the activity of hepatic transaminases, hepatocellular, cholestatic or mixed hepatitis, acute pancreatitis.
From the hematopopitation system: Very rarely - agranulocytosis, pancytopenia, leukopenia, thrombocytopenia, hypo-or aplasia of the bone marrow.
Allergic reactions: Hardwriter, skin rash, itching, bronchospasm, angioedema swelling, anaphylactic shock.
From the side of the cardiovascular system: Arrhythmia, bradycardia, AV blockade, decreased blood pressure.
From the nervous system: Headache, dizziness, drowsiness, increased fatigue, hallucinations, confusion of consciousness.
From the senses: Reducing visual acuity, noise in the ears.
From the side of the sexual system: With long-term use in high doses - amenorrhea, a decrease in libido, hyperprolactinemia, gynecomastia.
On the side of the musculoskeletal system: Malgy, Arthralgia.
Dermatological reactions: Alopecia, ordinary acne, dry skin.
Others: fever.
Overdose
Symptoms: Vomiting, motor arousal, tremor, decreased blood pressure, tachycardia, collapse.
Treatment: stomaching, symptomatic and supporting therapy; hemodialysis.
Medicinal interaction
Due to the increase in the pH of the contents of the stomach, Famotidin, with simultaneous use, reduces suction and itraconazole.
Antacids and sucralfat slow down the absorption of Famotidine. 1-2-hour break between the receptions of these drugs should be observed.
With simultaneous reception of Famotidine and medicines that depress bone marginal blood formation, the risk of neutropenia is increasing.
Famotidine increases absorption of amoxicillin and clavulanic acid.
special instructions
The use of Famotidine can mask the symptoms of the stomach cancer, therefore, before proceeding with the treatment of Famotidin, it is necessary to eliminate the presence of a malignant neoplasm.
Like all histamine H 2 blockers -receptors, with a sharp discontinuation of the treatment of Famotidin may cause cancellation syndrome, so the treatment is stopped, gradually reducing its dose.
Patients with violations of the Kvamatel liver function should be prescribed with caution and lower doses.
With long-term treatment of weakened patients or patients under stress conditions, bacterial gastric lesions are possible with the further spread of infection.
Quamatel should be taken after 2 hours after receiving itraconazole or ketoconazole in order to avoid a significant reduction in their suction.
Blockers of histamine H 2 receptors can inhibit the acid-containing effect of pentagastrine and histamine, so 24 hours before the test, it should be discarded from the appointment of Famotidine.
Gistamine H 2 Blockers receptors can suppress the skin reaction to histamine, leading to false-negative results of skin samples. Therefore, before conducting diagnostic skin samples to detect an allergic skin reaction of the immediate type, Famotidin should be canceled.
During treatment, the use of food, beverages and other drugs can be used, which can cause irritation of the stomach mucosa.
Impact on the ability to control vehicles and mechanisms
In the treatment period, patients should be taken care when managing vehicles and classes by other activities requiring increased concentrations of attention and speed of psychomotor reactions.
Pregnancy and lactation
The drug is contraindicated to use during pregnancy and in the period of breastfeeding.
With violations of the kidney function
Carefully: Renal failure.
When violations of the liver function
Carefully: Hepatic insufficiency, liver cirrhosis with portoystene encephalopathy as anamnesis.
Conditions of vacation from pharmacies
The drug is released by the prescription.
Terms and Storage Terms
The drug should be stored in an inaccessible for children protected from light place at a temperature not higher than 25 ° C. Shelf life - 5 years. Do not apply after the expiration date indicated on the package.
The prevalence of gastrointestinal diseases has recently increased not only among people, but also among animals. The main reason in both cases is the wrong power, in the risk group there are pets that are constantly powered by dry foods.
Before the admission of this drug requires consultation from the veterinarian
The mechanism of action of the drug is to reduce the production of gastric juice, at the same time the acidity and the proportion of the enzyme component is reduced. The main advantage of the drug is the lack of influence on suction while eating, which is very important. Many pet owners do not know how hard it is difficult to give a pet pill. Quathemal does not have a taste and smell, it is easy to hide it in the stern. It is also worth noting that it is possible to give medicine only after consulting a veterinarian, dosage compliance plays an important role.
Indications for the appointment of the drug
Quathemal is recommended for use with ulcerative lesions of the stomach and duodenum. Indications are also considered to be situations when it is required to reduce the production and acidity of the gastric juice, as well as the amount of gastric enzymes produced. Such a need may arise before the introduction of common anesthesia before carrying out the operation, the reception of the drug is considered excellent emission prevention into the respiratory pathways of the contents of the stomach.
Quamatel for cats is used for ulcerative lesions of the stomach.
Other readings:
- diagnosed gastric bleeding;
- niocecide gastritis;
- ulcerative colitis.
Important: the drug is intended both disposable and reusable reception. It shows the effectiveness in one-time attacks and conducting a long course of intensive therapy. It is actually about the universal drug, the maximum concentration of the main components in the blood is achieved in an hour, the duration of the drug is 12 hours.
Instructions for use and dosage of the drug for cats
The drug is produced in tablets and powder for the preparation of the solution. The main active substance is Famotidin, auxiliary components: Plumon, starch corn, lactose, magnesium stearate, talc, silicon colloid anhydrous.
In the absence of vomiting and nausea pills, it is recommended to take inside. Standard dosage of tablets depends on the mass of the animal, 1 kg accounts for 0.5-1 mg twice a day. The dosage of powder for B / B is calculated in the same way, the drug is also injected twice a day.
Contraindications and side effects
The drug is quite serious, so it should be applied only to the appointment of the veterinarian.
The drug is contraindicated to use with an anacid or hypoacid inflammation of the stomach, in this case it can lead to a painful death of the cat. The fact is that these types of gastritis are accompanied by a decrease in acidity and the weakening of the digestive properties of the gastric juice. The digestibility of food in the stomach becomes difficult, it begins to simply rot that he entails negative consequences. The same consequences are manifested when the dosage is exceeded, so the dosage should be observed.
Sideflines
In accordance with the instructions for use, the drug may be accompanied by the following side effects:
- digestive system - pancreatitis, constipation, hepatitis, meteorism, vomiting;
- the circulatory system is hypertension, blood breeding disorders, bradycardia, arrhythmia, deposition in whom.
After conducting long-term therapy, the quathemal ceases to stop his reception should be gradually, non-compliance with this recommendation threatens with strong gastritis and ulcers.
Important: It is also necessary to take into account that the drug has a property to block histamine receptors, so the drug intake must be terminated for the period of allergic samples.
Conditions shelf life and price
Quamatel is one of the best facilities based on Famotidine, so today it is applied in many clinical purposes. The drug action is well combined with other analogues, so ampoules and pills even among specialists deserve the most positive feedback. Next, we will give a detailed description of the instructions for its use.
What are the quamatels appoint?
Mostly Quatamel is used to treat defects associated with increased secretion of the entire gastric juice - i.e. With the problems of the digestive tract. In ampoules and tablets, the tool has the following testimony to use:
- any varieties of ulcers;
- with an open gastroesophagic disease.
In particular, the quamatel readings are directed not only for direct treatment of the designated stomach pathologies, but also to their prevention. In most cases, its use helps to avoid the development of a sharp postprandial hyperacid state. The last case is usually corrected by surgical intervention. It also applies to the general neutralization of pancreatitis.
Contraindications
In ampoules and pills quamatel completely contraindicated in the following cases:
- for those who suffer from lactose insufficiency;
- with pathologies in the work of the kidneys / liver;
- people who have not reached 16 years;
- during pregnancy and in the current period of lactation.
Also, quathemal can not be taken to those who have any intolerance to its structural components. This is very important, because In this case, the testimony indicates serious side effects.
Composition and form of release
It is produced in the form of tablets for internal reception, and in the form of a solution in ampoules for intravenously. Intravenous injections must be accompanied by an appropriate specialist recipe.
Quamatel instruction on the use of ampoule
If the ampoules are used, then it is necessary to conduct periodic infusions (intramuscular injections). It is necessary to do this in strict accordance with the instructions, and preferably only a professional. For direct intravenous drip gradual administration, the quamatel powder is bred carefully at a 0.9% solution of sodium chloride oxide and further combined with decompose oxide solution, conventional glucose, sodium dioxide chloride or ringer ratio. Such infusion is done throughout those set by 15-30 minutes.
Quamatel 40 mg, according to the instructions for use, you need to take inside only entirely, without fraction, and put water. They are covered with a special shell, so they are very quickly absorbed in the patient's stomach.
Solution
The quamatel solution as well as an analogues is intended strictly for intravenous injection by type of infusion or injection. For intravenous injection, this drug is introduced strictly very slowly, at least 2 minutes.
For cats and dogs quamatel
Useful actions for animals from a medication point of view are not yet established. The drug applies to people.
Quamatel instructions for use intravenously
For direct intravenous drip gradual administration, the quamatel powder is bred carefully at a 0.9% solution of sodium chloride oxide and further combined with decompose oxide solution, conventional glucose, sodium dioxide chloride or ringer ratio. The dosage is prescribed depending on the causes of the application, and it depends on each case.
Dosage in tablets according to the instructions
For adults, the reception of this drug is directly shown once in the current 24 mg maximum, or twice a day of 20 mg, over a period of 4-8 weeks. Take quamatel before eating or after meals it is possible, because No particular difference is observed.
Analogs of quamatel
The most popular is Famotidine and Ranitidine.
Cat owners and dogs are increasingly noting that their pets suffer from diseases of the stomach and intestines. Ailments arise on the basis of increasing acidity in the stomach. Quamatel for cats helps to successfully deal with this pathology. The drug is specially designed to treat digestive disorders.
Character of action of drug
The main reason for the development of the disease of the veterinarians is considered an incorrectly organized food process of cats. The risk group includes those animals that eat daily dry food without adding other products. We offer a description of how the drug is operating on the body of animals.
Quamatel successfully blocks Histamine type H2 receptors, reduces the intensity of hydrochloric acid production processes, thereby reducing the level of juice acidity, which is produced in the stomach.
The medication effectively removes the symptoms of the disease in cats, and also reduces the production of acid in their body. It acts directly on the cause of the disease, so veterinary doctors most often prescribe the drug to their patients.
Drug has several positive properties:
- does not affect the work of the internal organs and metabolic processes;
- does not reduce the amount of enzyme and hormones produced;
- the liver during medication does not suffer;
- therapeutic effect on the gastrointestinal tract has after 60 minutes, the active ingredient remains active throughout the day;
- in the intravenous method of introducing the quamatel after half an hour.
If the quamatel injection is made in the evening, then the medicine will suppress the production of hydrochloric acid all night for 12 hours. In the morning the cat will feel relief.
The drug at the same time reduces the secretion of gastric juice, surveillance and acidity. Suction is made regardless of the time of meals.
The owners know perfectly well that to use quamatel tablets for a cat is not easy, to persuade him to eat medicine is almost impossible. For the convenience of the tablet you need to smoke and add to the feed. The medicine does not smell and taste, so the animal will not notice his presence in food.
Assign a medicine and install a dosage veterinarian.
Forms of release
In the pharmacies of Moscow and other cities you can buy both the quamatel itself and its inexpensive analogue - Famotidin.
The drug manufacturer produces in different forms:
- standard tablets: Quamatel 20 or quamatel 40, depending on the volume of the active substance;
- 10 mg tablets (called quamatel mini), where the active component is present in small quantities;
- powder lyophilisate in ampoules for injections.
Packaging places 28 tablets of 20 mg, 14 - 40 mg and five ampoules of lyophilisate with a solvent. The main active substance in the composition of tablets - Famotidin.
Indications
Quamatels are used to treat the ailments arising due to increasing acidity.
Indications for the use of quamatel for cats:
- various problems with digestion;
- stomach ulcer
- gastritis;
- bleeding in the stomach;
- colitis.
The drug is also used during operations, as well as to prevent food from the stomach in the respiratory tract.
The lyophilisate and ordinary tablets are shown to treat diseases. Quamatel mini used with functional disorders. When there are no pathology, 10 mg tablets are used to eliminate signs of increased acidity.
The medication is effective in one-time reception to remove an attack, can also be used for course therapy. This is a universal means.
Reception rules
The dosage of the quamatel cat is calculated on the basis of the mass of the cat's body: up to 1 mg of the drug will be needed by 1 kg of weight. You need to eat medicine twice a day, it is better to give it a cat while eating.
The dosage of the solution prepared from the powder is set in the same way. Enter quamatel for cats intravenously twice for a day. Instructions for the use of quamatel for cats recommends taking pills if there are no bouts of vomiting. It is not worth experimenting with a quamatel, because no drug is absolutely harmless. Treatment with this medicine can be started after consulting a doctor.
Contraindications and side effects
The drug is forbidden to apply with two types of gastritis:
- hypoacid, when the gastric mucosa is inflamed and the secretion of glands is reduced;
- ancidne for which low acidity is characterized due to the atrophy of the stomach cells.
In both cases, the use of a quamatel leads to the painful death of the cat. The same thing expects a pet for overdose, so it is necessary to strictly follow the recommendations of the veterinarian. It should be remembered that with inflammation of the stomach mucosa, the quamatel stomach is categorically prohibited. Independently diagnosed with a cat and treat it at its discretion, since this can lead to unpleasant consequences.
The instruction warns about the possibility of side effects.
These include:
- pancreatitis
- flatulence,
- constipation,
- vomiting
- hypertension,
- cardiac arrhythmia
- flipping into a comatose state.
After a long course of treatment, the reception of the quathemal must be stopped gradually so as not to cause gastritis or ulcers.
Observing these uncomplicated rules, you can provide the necessary medical care to your cat and normalize its condition.
Quamatel for dogs - a drug that reduces the intensity of production in the stomach of hydrochloric acid. Thus, it reduces the acidity of gastric juice.
The drug for the treatment of duodenal ulceneous disease and stomach, as well as to eliminate digestion disorders, which can be caused by the high acidity of the gastric juice are applied. The active substance of this drug is the histamine receptor blocker. These receptors are located in the mucous membrane of the upper departments of the intestine and the stomach.
Activation them leads to enhanced hydrochloric acid production, and this leads to damage to the mucous membrane and digestion disorders. Quamatel blocks data receptors and normalizes acidity in the stomach.
Instructions for use and dosage quamatel for dogs
Reviews about the quamatel for dogs
Feedback №1.
For what I like the quamatel, so it is for the fact that, unlike many modern drugs, affects the cause of the disease itself, and not just removes the symptoms. Therefore, I always hold it in the first-aid kit. And although this is a human drug, it is actively used and for the treatment of dogs and helps them.
Veronica, Moscow
Feedback №2.
I had to be treated by a quamatel in a dog, the aggravation of the stomach ulcers, which was the result of an increase in the acid in the stomach. The only remark to the drug is that it is impossible to stop giving it sharply, the dog's body is accustomed to him. Just need gradually, day after day, reduce the dose. And if the animal has a liver pathology, you need to give a dose of less, as well as a weak dog.
Timur, Novosibirsk
Did you like it? Share with friends!
Loading ...