From cytovir 3 syrup in a child diarrhea. Positive reviews. Application during pregnancy and lactation

For flu therapy and a decrease in the likelihood of infection of pediatricians, Citovir-3 is often discharged for children. This is an immunostimulating and antiviral agent, which according to the instructions can be applied from the year.

Citovir-3 is available in syrup for children, powder, from which, when diluted with water, a solution and capsules are obtained.

Description

Cytovir-3 is a multicomponent medication, the therapeutic effect of it is due to vitamin C, bendazole and α-glutamal sodium tryptophan.

In addition to them, sucrosis and water is added to the syrup. In appearance, it is a colorless or yellowish liquid.

Solid capsules made from gelatin. They have a white housing and an orange cap, inside them a white or yellow powder that does not smell. The capsule as inactive components consists of milk sugar and E 576.

Powder is white, the presence of yellowness is allowed. Ready solution or does not smell, or smells orange, cranberry or strawberry. In the powder, fruit sugar is included as an inactive ingredient, he can also contain fragrances.

Citovir 3 refers to immunostimulating means. The main ingredients of the medication are effective against influenza viruses A and B and other ESVI causative agents.

The healing effect of the immunostimulator is explained by its active ingredients:

  • Bendazole launches in the body the formation process of its own interferon, which is necessary for the production of enzymes, overwhelming the reproduction of viruses. Active.
  • Alpha-glutamal-tryptophan sodium normalizes the number of T cells that support the normal state of immunity. This component enhances the immunomodulating effect of bendazole.
  • Vitamin C is a natural antioxidant, it protects the body tissues from the negative effects of free radicals, reduces inflammation. It activates immunity and increases the stability of the body to colds.

After oral taking Citovir-3, everything is absorbed from the gastrointestinal tract. Bioavailability of vitamin C reaches 90%, bendazole -80%, α-glutamal-tryptophan - 15%. Passing through the liver, bendazole and ascorbic acid are subjected to biotransformation, they are derived from urinous. In the body α-glutamyl-tryptophan using enzymes split to aminocarboxylic acids, which are involved in protein biosynthesis.

Indications

According to the instructions for the use of cytovir-3, children can be prescribed, both for the treatment of orvi prevention.

Restrictions and side effects

Citovir-3 syrup cannot be given to children with allergies on its active and inactive ingredients, during diabetes mellitus. Similar contraindications has powder.

Children suffering from diabetes, if they were 6 years old permitted to give Citovir-3 in capsules.

The drug, as a rule, is well tolerated, only can only be caused by allergies, which requires the completion of therapy and prescribeing antihistamine medicines. The reception of cytovir-3 can provoke hypotension, but after a while everything is normalized.

Instructions for use

According to the instructions for the use of cytovir-3, for the purpose of treatment and prevention are given by equal schemes. After the child prohibits the drug, feed it is permitted after half an hour.

The dosage of the immunomodulator varies depending on the age of the patient. Citovir-3 syrup for the treatment and prevention of ARVI in children are given in such doses:

It is necessary to give three times a day for 4 days. In order to prevent the medicine, the child can drink three or four times a year.

According to the same scheme, cytio-3 can be given in the form of a solution, to obtain it to the powder, pour 40 ml of the boiled cooled water and a pretty shake. The finished solution must be kept at a temperature of 0-8 ° C maximum of 10 days, after which it becomes unfit.

Citovir-3 in capsules for children over 6 years old need to drink 1 piece three times a day for 4 days.

Parents who give the child an immunomodulator must take into account the following:

  • Syrup must be stored at temperatures up to 25 degrees within 24 months from the date of production. The shelf life of the medicine in the remaining forms is 36 months.
  • Bendazole enhances the antihypertensive effect of diuretic and antihypertensive drugs. Fentolamine will potentiate a hypotensive effect from it.
  • Vitamin C increases the blood content of antibacterial agents of tetracycline and penicillin row. It improves the adsorption of iron-containing medicines. Ascorbic acid weakens the properties of anticular means, tricyclikles, antipsychotics, chronotropic effect from isoprenaline. Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline beverages reduce the adsorption of vitamin C. Barbituric acid derivatives accelerate the evacuation of ascorbic acid with urinic. When it is prescribed in a complex with salicylate and sulfanylamide means of a short action, the likelihood of salt diathythias increases. It lowers the level of contraceptives in the bloodstream.
  • If Citovir-3 is given to the child again, then it is necessary to periodically donate blood to determine the sugar content in the body.
  • It is impossible to give an antiviral remedy in doses above the prescribed by the doctor and instruction. If a medicine overdose occurred, then you need to apply for urgent help. In poisoning, the antidote is unknown, therefore, medications that eliminate the symptoms of intoxication are prescribed. Be sure to monitor the child's urinary system, blood pressure and sugar levels in the bloodstream in the child.

Price

How much is cytovir-3 for children depends on its form of release and on the markup of a particular pharmacy. The price of Syrope is about 380 rubles, powder - 330 rubles, 12 capsules - 320 rubles.

Analogs

There are no complete analogues of the drug Citovir-3, there are only medications with similar effects:

  • Orvire;

Orvire or Citovir 3 is better for a child?

Orvire is manufactured in syrup, which as the main ingredient contains Rimantadine. Medication is recommended for the treatment and prevention of influenza and children aged 1 to 14 years. Syrup can not with kidney and liver dysfunction, thyroid hyperfunctions. It may cause dyspepsia, pain in the stomach, insomnia, the bloating, refusal of food, headaches, weakening the concentration of attention. Both antiviral funds are not completely interchangeable and decide that the doctor should drink.

What better arbidol or cytovir-3 for children?

Arbidol - Russian drug, it happens in capsules, tablets and powder. Medication cannot be taken with hypersensitivity to its composition, otherwise it can cause allergies. It is resolved since 2 years, the kids younger than this age need to give Citovir-3.

Citovir-3 or Kagelin for a child preferable?

Kagelin is a domestic antiviral drug manufactured in tablets that can be used in children from 3 years. The medication is prohibited during allergies to its ingredients. More information about the Kagocele.

Citovir-3 or ergoferon for children more efficiently?

The action of homeopathic drugs has not been proven scientifically!

The analogues of Citovir 3 for children should select a specialist, since each of them has its advantages and cons.

Reviews

Opinion Mom and Dad

Parents who gave Citovir-3 noted that if the antiviral remedy was given at the very beginning of the disease, the effect is noticeable immediately. The temperature quickly falls. The drug is effective for the purpose of prevention, if you give it immediately after contact with an infected person, then the risk of infection is reduced. Negative feedbacks leave parents who noted the development of allergies in the child to Citovir-3.

The opinion of Dr. Komarovsky

Evgeny Olegovich believes that ORVI does not require treatment with medicines. If a baby has a flu, then the famous pediatrician advises him warmly dress, drink a lot, not feed through force. In addition, it is necessary to wash the nasal cavity with medicines based on sea salt, for example, with the help of marimer, aqua sialor. In the room where the child is located to constantly maintain cleanliness, the temperature is not higher than 20 ° C and the humidity of 50% -70%.

For 3 days in the body of the patient, the concentration of interferon reaches its maximum and the next day its well-being to improve. On the 5th day of the disease, immunoglobulins are produced and for 6 days the fever passes. When the child's condition is not improving for 4 days or after normalizing the well-being, it has become worse than handing over blood. The survey will detect secondary bacterial infections. When they are connected, it is necessary to apply an antibiotic.

Evgeny Komarovsky believes that Citovir-3 with a viral infection is useless, the patient's body itself to defeat the disease.

The immunomodulator is released on a prescription form, so it is impossible to give it without negotiation with the doctor. The doctor will say how to drink cytovir-3 for treating and preventing children.

The immunomodulating drug of cytovir-3, which affects the reaction of cell, humoral immunity and non-specific organism resistance. It has an interferonogenic effect.

The preparation of bendazole induces the production of endogenous interferon. The enzymes induced by interferon in the cells of various organs inhibit viruses replication. In addition, activating immunocompetent cells, the drug contributes to the normalization of immune status.

Timogen acts on T-cell immunity. Ascorbic acid activates humoral immunity, normalizes the permeability of capillaries, thereby suppressing the inflammatory process.

Pharmacokinetics

Suction

After receiving the inside of Citovir-3 completely absorbed from the gastrointestinal tract. Bedazole bioavailability is about 80%, thymogen - no more than 15% and ascorbic acid - 90%.

Metabolism

Timogen under the influence of peptidases is split into L-glutamic acid and L-tryptophan, which are used by the body in protein synthesis.

Election

The metabolites of ascorbic acid and bendazole are outlined with urine. T 1/2 components does not exceed 3 hours.

Indications

prevention and symptomatic treatment of early influenza and other ARVI.

Instructions for use / dosage

The drug cytovir-3 is taken inwards 30 minutes before meals.

For the purpose of prevention and treatment with adults and children over 6 years old are prescribed 1 caps. 3 times / day for 4 days.

Children aged 1 to 3 years are prescribed 2 ml of syrup 3 times / day for 4 days; Children aged 3 to 6 years - 4 ml 3 times / day for 4 days; Children aged from 6 to 10 years - 8 ml 3 times / day for 4 days; Children over the age of 10 years - 12 ml 3 times / day for 4 days.

With prophylactic goal re-course treatment can be carried out in 3-4 weeks.

Side effect

From the side of the cardiovascular system: A short reduction of blood pressure (in patients with neurocirculatory dystonia).

Others: Allergic reactions .

Contraindications

diabetes mellitus (for syrup);

children's age up to 6 years (for capsules);

pregnancy (for capsules);

lactation period (for capsules);

increased sensitivity to the components of the drug.

Application in pregnancy and breastfeeding

The drug is contraindicated to use during pregnancy and during lactation.

Application with violations of the kidney function

With long-term use, periodic monitoring of the kidney function is necessary.

special instructions

With prolonged use of syrup, periodic monitoring of kidney function and blood glucose levels are required.

Overdose

Data overdose of the drug Citovir-3. not.

Medicinal interaction

Medicinal interaction of drug Citovir-3. Not described.

Syrup for children for the prevention and treatment of Orz and flu Citovir-3dovochka who gave children ??? Instead of Viferon, Anaferon, and so on. There are good reviews in the internet: here is one of them: when once again, the daughter came from a kindergarten with a general malaise, and in the evening there was also a temperature rose, I decided to start the Cytovir-3 course. Gave immediately and daughter (3.5 years) and son (year). The next morning the temperature did not happen, and the son was not infected. And when we drank the whole course, we went with new forces ...

Timogen Spray is working

From antiviral syrup-tablets, I always preferred cytovir. He really worked if he began to give it on the first day of the disease. A little later, the same pharmacist. The company has released thymogen, there is a solution (not tried) and spray in the nose. The absorption of the same active substance is carried out through the nasal mucosa. I thought, it's convenient, 1 pshik per day in 1 nostril. (He learned about the drug from his family doctor, she is aware of all new products, etc.) Sample 1. In the summer before the sea, they bought it and took it with ...

Citovir 3 is an inexpensive combined immunomodulator, preferably used for the treatment or prevention of colds infectious diseases (ORZ). One of his key advantages is the minimum of side effects and the ability to use in pediatrics (for the treatment of children). What instruction on application to cytovir 3? What forms is it produced? How is it combined with other pharmacological preparations, in particular, immunomodulators?

According to the instructions of the manufacturer, the testimony for the use of cytovir 3 is the treatment and prevention of sharp respiratory diseases of viral etiology. However, with bacteriological or fungal infection, the immunomodulator also acts, but less pronounced, since the components included in its composition enhance the effectiveness of an atypical immune response (by stimulating the synthesis of interferon). In addition, ascorbic acid (vitamin C) in the therapeutic dose is included in Citovir 3. This has a positive effect on the general sustainability of the body to infections.

The drug includes:

  • Bendazole (substance that stimulates the synthesis of interferon);
  • Sodium thymogen (affects the T-cell immune system, thereby enhancing the effectiveness of interferon);
  • vitamin C (promotes the overall imminent strengthening).

It is also worth noting that the composition of the drug is selected in such a way as to ensure its maximum bioavailability. That is, it starts to act as quickly as possible after the reception.

Forms of release

Currently, cytovir 3 is available in the following forms:

  • capsules (package at 12, 24 and 48 pieces);
  • syrup (for children);
  • powder for making a solution (for children).

The concentration of active ingredients is specified in the table.

The powder for the preparation of the solution is produced in three variations, which differ in each other for the form of a natural flavoring. At the moment there are three variations:

  • cranberry;
  • strawberry;
  • orange.

The form of the flavoring in no way affects the therapeutic effect of the drug and can be selected at its discretion by the patient (or parent). On the likelihood of an allergic reaction, this parameter also does not affect in any way.

Instructions for use

Cytovir 3 capsules are taken 20-30 minutes before meals, drinking with a small amount of water. Syrup is a ready-made solution for receiving, but, if necessary, it can be divided into water temperature directly before use.

It is worth noting that the course of admission and dosage both in the treatment and during the prevention of ORZ does not change, but can be corrected at the discretion of the attending physician.

At temperature, the reception scheme does not change, but it is recommended to take a break in 2-3 hours between the intake of immunomodulators and antipyretic drugs (for example, paracetamol).

With regard to the combination of cytovir with other drugs, the manufacturer indicates that it is well tolerated and together with antipyretic, and with antibiotics, and anti-inflammatory means. The only note is not to combine reception with other immunocorrectors. And even between the reception of drugs should take a break in 1-2 hours.

Contraindications

A categorical contraindication for taking cytovir 3 is the presence of hyperreaction per one of the components that are part of the drug, vegetative dystonia, hypotension. It is also not prescribed under the age of 6 years (does not apply to syrup or powder for the preparation of the solution, which is allowed to be applied in practice from 3 years). According to doctors, the reception of Citovir 3 should be limited in atypical chronic immunodeficiency, in order not to provoke an autoimmune response (but it was not conducted for detailed research, so the manufacturer does not indicate a manufacturer in the instructions).

It should also be borne in mind that the Cytovir 3 capsules are in a small amount of lactose. But with its intolerance, the symptoms of the intestinal disorder can occur, diarrhea. In this case, it should be consulted with the attending physician regarding the possibility of replacing the drug on analogue. Or you can use another form (syrup or powder for the preparation of the solution). In their composition lactose no (as it is only in the shell capsules).

Dosage

And for the treatment of ORZs in the composition of complex therapy, and for the prevention of respiratory diseases Citovir 3 takes 1 capsule 3 times a day 20-30 minutes before meals, drinking them with a small amount of water. The course of treatment is 3-5 days, after which a break is made in 2-3 weeks (or according to the diagram specified by the doctor).

Citovir 3 in the form of a syrup is taken with the following dosage:

  • for children from 1 to 3 years old - 2 millilita 3 times a day;
  • for children from 3 to 6 years - 4 millilita 3 times a day;
  • for children from 6 to 10 years old - 8 milliliters 3 times a day;
  • for children from 10 to 12 years old - 12 milliliters 3 times a day.

The powder for the preparation of the solution is initially mixed with boiled water temperature (40 milliliters of water on the contents of 1 package). Further dosage is identical to the one that is indicated for the syrup.

Syrup and a finished powder solution should be stored in a dark place protected from sunlight at a temperature of from 0 to 8 degrees Celsius.

Possible side effects

With pronounced vegetative-vascular dystonia, the drug intake can provoke an arterial hypotension. Also, the manufacturer reports the known single cases of an allergic reaction manifested in the form of:

  • urticaria;
  • tear;
  • short-term body temperature increase.

An approximate percentage of possible hyperreaction is only 0.001%. Tests on this account were not conducted, no certified statistics. As practice has shown, the allergic reaction mainly occurs in children up to 3 years of age.

With lactose intolerance, diarrhea, intestinal disorder can also occur. In some patients, this is complemented by a slight pain in the stomach due to the increased secretion of enzymes. Immediately after stopping the reception of Citovir 3, these symptoms disappear.

Price

At the moment, the average price in the pharmacies of the Russian Federation on the cytovir 3 is:

  • capsules (12 pcs.) - 337 rubles;
  • capsules (24 pcs.) - 530 rubles;
  • capsules (48 pcs.) - 854 rubles;
  • syrup (50 ml) - 417 rubles;
  • powder for preparing a solution (20 grams) - 316 rubles;
  • powder for the preparation of the solution (20 grams, cranberries) - 282 rubles.

The final price may differ somewhat from the above, as it depends on the region, the financial policy of the pharmacy network, the delivery time.

Analogs

There is no identical to the composition of drugs in pharmacies, but there is a mass of cheap Citovir 3 analogues with a similar effect. These include:

  1. Amixin (in the form of tablets). The active ingredient is Tiloron, which also stimulates the synthesis of interferon. It is used in the treatment of many infectious diseases, including hepatitis A. The average cost - 235 rubles.
  2. Glutoxim. The base is a solution of wildlutsima in ethanoic acid. It is used not only in immunodeficiency, but also to brake the process of dividing cancer cells. Acts comprehensively. The average price is 1180 rubles.
  3. Anaferon. The base is the purified body of gamma interferon. Best is suitable for the prevention and treatment of viral respiratory diseases. It can be used for children (a special "children's" form of the drug is produced). The average cost is 190 rubles.
  4. Kagelin. The base of the drug - Kagocel, which is a synthetic inductor of interferon. There is no worse than Citovir 3 at all, but there were no detailed clinical trials.
  5. Interferon. Enhances the complex function of immunity, especially effective against viruses. Used including pediatrics. The only drawback is the release form (ready-made solution in ampoules). The average price is 200 rubles.

According to annotation in the official instruction, it is not necessary to switch to the reception of the drugs-analogs. This decision can only take the attending physician in the presence of a complete clinical picture and the history of the patient's disease.

Overdose

Neither the manufacturer nor doctors on cases of overdose drugs are not known. One can only assume that the symptoms will be similar to those that occur when interferon derivatives occur. And this is the possible manifestation of an allergic reaction:

  • hives;
  • local redness, inflammation of the skin;
  • local itching and peeling of the skin.

In case of overdose, adhere to the same actions as in poisoning by any other pharmacological agent. That is, it is possible to clean the stomach as soon as possible, take activated coal, seek medical help. Naturally, taking the drug temporarily suspend.

Thank you

The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!

Citovir It is an immunostimulating drug, intended for the prevention and treatment of influenza or sharp respiratory viral infections in children and adults.

Name of Citovir-3

The drug is correctly called "Citovir-3", however, in practice in everyday speech, the figure three is often discarded, and called the medicine simply "cytovir". Thus, "Citovir-3" and "Citovir" is the same drug that is simply called differently.

Composition, description, form of release and manufacturer

Currently, the drug cytovir is produced in three dosage forms:
  • Syrup for children;
  • Powder for making a solution for receiving inside (for children);
  • Capsules for receiving inside.
All three Citovir dosage forms are produced by CJSC "Medico-Biological Scientific and Production Complex" Citomed ", Russia, 191023, St. Petersburg, Flour Lane, House 2.

Syrup

Cytovir syrup is a liquid of colorless or yellow, intended for receiving inside by children from one year. Syrup is produced in dark glass bottles with a volume of 50 ml, which are stacked in a cardboard box complete with a dosing device (measuring cup, dosing spoon or dosing pipette).

Syrup as active ingredients contains three substances - this is alpha-glutamal-tryptophan sodium (sodium thymogen), ascorbic acid and bendazole hydrochloride (dibazole). In 1 ml of syrup, contains 0.15 mg of alpha-glutamal-tryptophan, 12 mg of ascorbic acid and 1.25 mg of bendazole hydrochloride.

As auxiliary components, cytovir syrup contains only two substances - purified water and sucrose.

The shelf life of the Citovir syrup is 2 years from the release date. It is impossible to use the drug after its expiration date. Store syrup should be in a dark place at air temperature not higher than 25 o C.

Powder

Citovir solution Powder is a homogeneous powder mass painted in white or yellowish color. The finished solution made from the powder is transparent, blunder or has a yellowish tide. Citomed solution is designed for children older than one year.

The powder for the preparation of the solution is produced in four varieties - without flavors, with the aroma of strawberries, orange or cranberries. Accordingly, if the powder does not contain flavors, then the finished solution from it will also not be smell. And powders with flavors and finished solutions will give the appropriate orange, strawberry or cranberry smell.

Powders for the preparation of a solution of cytovir are packaged in 20 g in dark glass bottles or polymer plastic bottles. In turn, the Powder bottle is placed in a cardboard box along with instructions for use and a device for dosing the finished solution (measuring cup, a measurable spoon or dosing pipette).

Cytovir powders without flavoring and flavors as active components contain three substances - this is alpha-glutamal-tryptophan sodium (sodium thymogen), ascorbic acid and bendazole hydrochloride (dibazole). The number of active components in powders is such that in 1 ml of the solution prepared from them contains 0.15 mg of alpha-glutamal-tryptophan, 12 mg of ascorbic acid and 1.25 mg of bendazole hydrochloride.

As auxiliary components, all four types of powder for the preparation of a solution contain a lactose monohydrate and fructose. And the powders with flavors additionally also contain both the corresponding aromatic additives "Orange", "Strawberry" or "Cranberry".

The shelf life of the Citovir powder is 3 years from the date of its release. However, it should be remembered that a three-year storage period concerns only the powder itself, since the finished solution is suitable for use only 10 days. Thus, the drug can be stored in a powder, without preparing a solution from it for three years. In this case, the bottle with a powder should be kept in a dark and dry place at an air temperature not higher than 25 o C. But the finished solution from the powder can be stored only 10 days, after which it is simply poured, if they did not have time to use. The finished solution is stored only in the refrigerator at a temperature of 2 - 8 o C, without being freezing.

Capsules

Cytovir capsules are solid oval cylinders from gelatin with a white housing and an orange lid. Inside the capsules there is a homogeneous powder of white or white-yellow color without smell. Capsules are packed in cardboard boxes of 12, 24 or 48 pieces. Cytovir in the form of capsules is designed for adults and children over 6 years old.

As active ingredients, each capsule contains alpha-glutamal-tryptophan sodium in an amount of 0.5 mg + ascorbic acid - 50 mg + bendazole hydrochloride - 20 mg. As auxiliary components, the powdered mass inside the capsules contains lactose monohydrate and calcium stearate. Capsules are made of gelatin in a mixture with titanium dioxide. Orange capsule capsules also contains dyes - solar sunset yellow and azorubin.

The shelf life of Citovir capsules is three years from the date of release. Store capsules follows in a dark dry place at an air temperature not higher than 25 o C.

Tablets Citovir

In the form of tablets, the drug Citovir is not available. There are only capsules, syrup and powder for intake. Therefore, if the pills implies a "adult" dosage form, then it should be about capsules.

Therapeutic action

Thanks to its composition, the cytovir's active substances have an immunostimulating effect. Such an immunomodulatory action consists in enhancing the activity of immune cells, which are influenced by faster and more efficiently, and destroy the influenza a and c viruses, as well as viruses causing ARVI.

Thus, alpha-glutamal-tryptophan (thymogen) enhances the activity of T-cells of the immune system, which are responsible for the destruction of viruses.

Bendazole stimulates the production of interferon in various organs and tissues, which, in turn, activates the operation of almost all cells of the immune system. Thus, due to the powerful activation of all immune cells, the faster and efficient destruction of viruses and cells infected with them occur. In addition, the influence of interferon is suppressed by the reproduction of the virus particles themselves.

Ascorbic acid activates the work of B-cells of the immune system, which produce antibodies for viruses, bacteria, fungi and other pathogenic microorganisms. Due to the effect of ascorbic acid, viruses and cells infected with them are destroyed by antibodies synthesized in large numbers. In addition, ascorbic acid normalizes the permeability of capillaries, which under the action of viral toxins become literally holes, passing the liquid part of the blood through the walls, which forms swelling and inflammation. Thanks to the ascorbic acid, the capillaries cease to pass fluid from the blood in tissue, as a result of which the swelling and activity of the inflammatory process decreases. Also ascorbic acid increases the body's resistance to various infectious diseases.

Thus, due to the integrated action of its active components, cytovir is able to reduce the severity of symptoms and reduce the duration of the influenza and ARVI.

Suction, distribution and elimination of the body

When admitting inside in any form (syrup, capsules, a solution cooked from the powder), the cytio is completely absorbed into the systemic blood flow from the gastrointestinal tract. Ascorbic acid consisting of cytiora is worse in the preparation of the drug simultaneously with fresh vegetable and fruit juices.

Ascorbic acid after entering the liver turns into oxideuxous and diquculonic acid. Ascorbic acid from the body of the kidneys, through the intestines, with then both breast milk, both in constant form and in the form of metabolites (oxaloneacetic and disconnecting acids).

Bendazole in the blood under the action of enzymes also forms other substances - metabolites, which are derived from the body with urine kidneys.

Alpha-glutamal-tryptophan in the blood under the influence of enzymes is split into amino acids glutamine and tryptophan, which are used by the organism for protein synthesis.

Indications for use (capsules, syrup, powder for the preparation of solution)

Powder, syrup and cytovir capsules are shown to use for the prevention and treatment of influenza, as well as sharp respiratory viral infections (ARVI) in children and adults.

It is necessary to remember that for the treatment of influenza and ORVI, the cytovir preparation is shown to use as part of comprehensive therapy. And for the prevention of cytovir, only one can be used, without additional drugs.

You also need to know that cytovir capsules are designed to receive adults and children over 6 years old. And the syrup and solution from the Citovir powder is shown for children over 1 year, but under 18 years of age.

Instructions for use

Instructions for the use of Citovir-3 powder

Citovir powder is designed for the preparation of a solution that is taken inside the children over one year for the prevention and treatment of influenza and ARVI.

Before use of powder, you need to prepare a solution that gives children to children. To do this, the bottle with a powder opaque and 40 ml of boiled water cooled to room temperature is added to it. Close the bottle with a lid, shake vigorously several times, achieving the complete dissolution of the powder. When the whole powder is dissolved, the solution is ready for use. For storage, it is immediately removed in the refrigerator. The volume of the resulting finished solution is 50 ml.

It should be remembered that for the preparation of the solution you need strictly cooled boiled water. It is impossible to breed the powder with boiling water or hot water, since the decay of the active components of the medicine will occur under the action of high temperature, and it will eventually be useless. It is also necessary to know that for measuring 40 ml of water, it suffices to use the usual, which are 10 or 20 ml in a pharmacy. Such syringes can easily measure the necessary 40 ml accurately.

A solution prepared from the powder must be stored in the refrigerator at a temperature of from 2 to 8 o C, not allowing, however, its freezing. The solution that was subjected to freezing is considered unsuitable for further use, so it will have to be thrown and instead to prepare a new one. A solution of cytovir after cooking can be stored in the refrigerator to a maximum of 10 days, after which it is spoiled and becomes unsuitable for use. If within 10 days the whole solution is not used, then it is necessary to throw it out and, if necessary, continue treatment, make a new one.

Citationary solution is given to children in identical dosages for the treatment and prevention of influenza and ARVI. Doses are different depending on the age of the child. So, for the prevention and treatment of influenza / ORVI, it is recommended to give children a solution made from a powder in the following dosages depending on age:

  • Children at the age of 1 - 3 - give to drink 2 ml of the solution 3 times a day;
  • Children at the age of 3 - 6 years - give 4 ml to drink three times a day;
  • Children at the age of 6 - 10 years - give to drink 8 ml of the solution three times a day;
  • Children at the age of 10 - 18 - give to drink 12 ml of the solution three times a day.
Cytovir solution give children to drink half an hour before receiving food. It is possible to drink a solution with water or compote, and undesirable juice, since the latter reduces the absorption of ascorbic acid from the intestine and the stomach. For young children, it is permissible to make the required amount of cytovir solution in water or compote, and give a drink in this form.

The desired amount of the solution is measured by an attached dosing spoon, a pipette or a measuring cup. After each use, the dosage fixture is rinsed with warm water. If the dosage device has lost or broke, then instead you can use the usual one-time syringe of the corresponding volume, bought in the pharmacy.

A solution from the Citovir Powder for the treatment and prevention of influenza and ARVI gives children for four days. At the same time, if on the background of treatment, there was no improvement for three days of receipt of the drug, then its use should be discontinued and consult a doctor. In order to prevent the drug, you can take four-day courses every 3 to 4 weeks.

Since the powder and the solution contains sugar, then during repeated uses of the drug, it is necessary to control blood glucose levels. Patients suffering from diabetes must remember the presence of sugars in the composition of the solution of Citovir.

Instructions for the use of syrup Citovir-3

Citovir syrup is ready for use and used to treat and prevent influenza and ARVI in children aged 1 - 18 years. Before applying the bottle with syrup you need to shake to mix its contents well. The opened vial can be stored at room temperature or in the refrigerator, but not allowing its freezing.

Syrup give children for half an hour before meals. You can drink syrup with water or compote. In addition, if a child is capricious and it is difficult to persuade the adoption of the medicine, you can dose in water or compote, and give a drink to the baby. But at the same time it is necessary to ensure that the child drank the entire volume of this fluid with the medicine dissolved in it. It is undesirable to damage the syrup with juices or plates, since they worsen the absorption of ascorbic acid into the blood flow from the digestive tract.

Dosages for the prevention and treatment of influenza / ORVI syrup Citovir are the same. Dosages differ only depending on the age of the child. So, syrup is recommended to give children for the treatment and prevention of influenza / ARVI in the following dosages:

  • Children aged 1 - 3 years - to give 2 ml of syrup three times a day;
  • Children at the age of 3 - 6 years - to give 4 ml of syrup three times a day;
  • Children at the age of 6 - 10 years - to give 8 ml of syrup three times a day;
  • Children aged 10 - 18 years - to give 12 ml of syrup three times a day.
The duration of the course of treatment and prevention of cytovir syrup is 4 days. If within three days of treatment, the state of the patient child has not improved or new symptoms appeared, then the citemir should be discontinued and console to the doctor. For prevention, the drug can be taken by courses for 4 days every 3 to 4 weeks.

It should be known that when repeated applications of the syrup cytovir, it is necessary to hand over blood test to the glucose concentration, as the drug contains sugars. Also suffering from diabetes should be remembered about the content of sugars in the cytovir syrup.

Instructions for use Capsules Citovir-3

Capsules Citivovir are designed for adults and children over 6 years old with the aim of treating and preventing influenza and ARVI. Capsules are ready for use. Capsules should be taken in half an hour before meals, swallowing them entirely, not shaking and not chewing, but drinking a small amount of water.

Dosage Capsules Citovir for children and adults is the same. In order to treat influenza or ORVI, one capsule should be taken three times a day for four days. If, after three days, there was no improvement or new symptoms appeared, the reception of cytovir is stopped and accessing the doctor.

To prevent Capsules, cytovir is taken in two possible modes. If a child or adult contacted a person with a sick influenza or an ARVI, the cytovir for prevention takes one capsule three times a day for four days. And during the periods of seasonal epidemics and outbreaks of ARVI / influenza, children and adults who have not contacted patients take cytovir on one capsule one time per day for 12 days. Preventive reception of cytovir in any mode can be repeated through each month until the seasonal outbreak of ORVI / influenza is disappeared.

Overdose

For the entire period of observation over the use of powder, syrup and cytovir capsule, no overdose cases have been registered. However, theoretically an overdose is possible, and it is manifested by a short-term decline in blood pressure, especially in the elderly people or suffering in vegetative-vascular dystonia.

When signs of overdose appear, "ambulance" should be called and hospitalized in the hospital, where doctors will control the work of the kidneys, blood pressure level and blood glucose concentration.

Application during pregnancy and breastfeeding

During the entire pregnancy, the capsule, powder and syrup cytovir are contraindicated to use due to the fact that there are no accurate and clear security data for the fetus, the flow of pregnancy and childbirth.

The reception of cytoviro simultaneously with fantolamine enhances the effect of reduced blood pressure.

Ascorbic acid increases the concentration in the blood of antibiotics of the tetracycline group (tetracycline, doxycycline, etc.) and benzylpenicillin, but reduces the concentration in the blood of oral contraceptives. Ascorbic acid also reduces the severity of the action of heparin, indirect anticoagulants (for example, warfarin, pheniline, etc.), phenothiazine and isoprenaline.

Ascorbic acid increases the rate of removal of drugs with an alkaline reaction and reduces the selection rate of drug-acids (aspirin, etc.). Ascorbic acid also accelerates the removal of amphetamine and tricyclic antidepressants (amitriptyline and other). In addition, ascorbic acid enhances the absorption of iron in the digestive tract.

Acetylsalicylic acid (aspirin), oral contraceptives (Diana 35, Marvelon, Jes, Clair and others), fresh juices and alkaline mineral water worsen ascorbic acid absorption in the digestive tract. And the prison and barbiturates (Veronal et al.) Accelerate the removal of ascorbic acid with urine.

In addition, the simultaneous reception of cytovir with acetylsalicylic acid or sulfonamide (biseptol, grossptol, streptocide, etc.) increases the risk of saline crystals in the urine.

Powder, capsules and cytovir syrup can be used simultaneously with other antiviral drugs and means for symptomatic treatment of ARVI and influenza.

Side effects

Powder, syrup and Citovir capsules as side effects can provoke a short-term reduction in blood pressure or various allergic reactions (urticaria, skin itch, etc.).

In the event of the development of allergic reactions, the reception of the drug is stopped, and treatment with antihistamine means (for example, suprastine, phenyatil, zyrtek, Claritine, Parliament, Tefastom, Erius, etc.).

If, against the background of treatment, there were any other, not specified adverse reactions, then immediately stop receiving the drug and consult a doctor. Also, you need to contact the doctor if the side effects are enhanced.

Contraindications for use

Citovir syrup and powder are contraindicated to use if the child has the following states or diseases:
  • Pregnancy period;
  • Age under one year;
  • Diabetes;
  • Lactase deficiency;
  • Glucose-galactose malabsorption.
Capsules Citovir are contraindicated to use in the following states and diseases:
  • Individual increased sensitivity or allergic reactions to any components of the drug;
  • Thrombophlebitis or leakage to thrombosis;
  • Elevated muscular tone;
  • Atopic form (allergic) bronchial asthma;
  • Pregnancy;
  • Age older than 6 years.
With caution capsule, powder and cytovir syrup should be used in arterial hypotension (reduced arterial pressure). It is also necessary to abide by caution when using cytovir at the background of the reception of the drugs of the anticoagulant group (for example, warfarin, thrombostop, pheniline, etc.), since ascorbic acid contained in cytovirum decreases the severity of the therapeutic effect of anticoagulants.

Citovir-3 for children

General information and rules for choosing a dosage form

For the treatment and prevention of influenza and ARVI, cytovir in the form of powder and syrup, which can be given to the kids from one year, are intended for the treatment of influenza. Both powder and syrup are specialized children's forms of the drug, which can be easily dosed and giving babies. That is why it is best for children of preschool and younger school age to give cytovir in powder or syrup.

Children over 6 years old can be given cytovir and in capsules if they do not have difficulty with their swallowing and prefer to drink capsules / tablets, and not syrup or medication solution.

Thus, it becomes obvious that the children of 1-6 years old can be given a cytiomer only in powder or syrup, and syrup, and a solution of powder, and capsules can be given to children over 6 years old. In fact, the choice of dosage form of the Citovir is facing parents only for children over 6 years old.

From the point of view of saving it is more profitable to give a child over 6 years old drug in capsules, since in this case only 12 capsules or 1 package will be needed on the course of therapy or prevention. But a syrup or powder for children 6 - 10 years will need 2 bottles, and for children over 10 years old - three bottles. Accordingly, if a child over 6 years old can swallow capsules without problems, it is better to prefer this dosage form. But if the baby even over 6 years old is difficult to swallow capsules, then the cytovir in powder or syrup should be given it.

Instructions for the use of the drug in children (syrup, powder and capsules)

Capsules and cytovir syrup are ready for use, and the powder before use you need to breed with water to obtain a solution that is intended for reception inside.

For powder breeding, cool boiled water is needed - not hot, no boiling water, namely room temperature, since the high temperature will lead to the decay of the active components of the drug and make it useless. To obtain a solution, a conventional one-time syringe is measured with 40 ml of boiled water of room temperature, and they contribute to the bottle with the Citovir Powder. Then the bottle is closed with a lid and shake until the powder is completely dissolved. The volume of the obtained finished solution is 50 ml.

The finished solution of cytovir stored strictly in the refrigerator, but not allowing its freezing. The solution of cytovir is suitable for use for only 10 days, after which it is necessary to simply be thrown.

Syrup and capsules can be stored both in the refrigerator and at room temperature. Some suitable for use 2 and 3 years, respectively, from the date of release.

Syrup, a solution of powder and capsule Citovir for treatment and prevention give children for half an hour before meals. Capsules need to be littered with a small amount of water, and the solution and syrup can be stored, and it is possible. Water is allowed to be replaced by compotes, but it is impossible to pick up juices or frost to give a child, since they worsen the absorption of ascorbic acid, which is part of the drug. Syrup and solution can also be divorced in water or compote, and give a drink to a child in this form.

Dosage of solution, syrup and capsules for treating influenza and ARVI in children of different ages are as follows:

  • Children aged 1 - 3 years - to give 2 ml of syrup or 2 ml of powder solution three times a day;
  • Children at the age of 3 - 6 years - to give 4 ml of syrup or 4 ml of powder solution three times a day;
  • Children at the age of 6 - 10 years - to give 8 ml of syrup, or 8 ml of powder solution or one capsule three times a day;
  • Children at the age of 10 - 18 are 12 ml of syrup, or 12 ml of powder solution, or one capsule three times a day.
The duration of the course of therapy with solution, syrup, or cytovir capsules in children of any age is four days. It should be remembered that if within three days the child did not become better or new symptoms appeared, then the citemir should be discontinued and consult a doctor to appoint other treatment.

In order to prevent influenza and ORVI syrup and a solution from the Citovir Powder, children are given in the same dosage as for treatment, and also within four days. Such prevention courses can be repeated every 3 - 4 weeks.

But the capsules for children for the prevention of ORVI or influenza can be given in two different modes. If a period of seasonal epidemics simply came, and the child did not contact with patients with influenza / ORVI, then for prevention, they give one capsule per day for 12 days. Such prevention courses can be reassembled with a break between them at least one month. And if the child contacted the patient with the influenza or ARVI, then to prevent the disease, it gives a cytovir in one capsule three times a day for four days.

Analogs

The drug Citovir in the pharmaceutical market has only the-analogs, which contain other active substances, but provide a similar antiviral action and are intended for the treatment and prevention of influenza / ORVI.
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