Most often, in the treatment of rhinitis, patients choose vasoconstrictors because of their ease of use, quick effect, and moderate cost. Many people trust these remedies as proven medicines. One of the effective, affordable and safe means, which has a vasoconstrictor effect, is “Xylene”.
Composition, release form, packaging
The medicine in question is produced in the form of nasal drops. The active ingredient of the drug is xylometazoline hydrochloride.
The following auxiliary components are used in the manufacture of drops:
- disodium edetate;
- benzalkonium chloride;
- sodium hydrogen phosphate dodecahydrate;
- potassium dihydrogen phosphate;
- purified water;
- sodium chloride.
The drug is produced in the form of drops with virtually no color. Clear liquid may be slightly colored. Drops are produced with the following dosage:
- 0.0005 g/ml (0.05%). Used in the treatment of children 2 – 6 years old;
- 0.001 g/ml (0.1%). Used in the treatment of patients over 6 years of age.
The transparent liquid is contained in bottles made of colorless or light-protective glass. Drops are also produced in polymer dropper bottles. The medicine is produced in a volume of 10 ml. The cardboard box contains a bottle of drops and instructions for use. The pack may also contain a pipette/dropper cap.
Manufacturer
The trade name of the drug in question is “Xylen®”. It has international generic name– xylometazoline.
The manufacturer is LENS-Pharm LLC, which is a subsidiary of Veropharm OJSC. The production address is Belgorod, st. Rabochaya, 14.
Indications
Nasal drops are prescribed if the patient has the following diseases:
- acute respiratory diseases accompanied by rhinitis;
- sinusitis;
- sinusitis;
- spicy allergic rhinitis;
- otitis media(V complex therapy in order to reduce swelling of the nasopharynx, but can also be instilled into the ear).
Drops can also be used to facilitate a diagnostic procedure such as rhinoscopy after nasal surgery (septoplasty, etc.).
Contraindications
The drug has few contraindications for use. They are represented by the following positions:
- glaucoma of any etiology;
- intolerance active component, any of excipients;
- atrophic form of rhinitis;
- lactation period;
- advanced atherosclerosis;
- pregnancy;
- severe tachycardia, hypertension;
- presence in the anamnesis surgical interventions in the area of the meninges.
Mechanism of action
Xylometazoline is part of a group of local vasoconstrictors that exhibit alpha-adrenomimetic activity. The drug helps to narrow the blood vessels in the mucous membrane of the nasal cavity.
The active substance has the following therapeutic effects:
- relieving hyperemia and swelling of the mucous membrane;
- relief of nasal breathing;
- restoration of patency of the nasal passages.
The therapeutic effect of nasal drops is observed after several minutes (3 – 5) after instillation, it lasts about 10 hours.
After local use the medication is practically not absorbed (the concentration of the active substance in the blood plasma is very low).
Instructions for use
- For adult patients and children over 6 years of age, Xylen is instilled with a dosage of 1 - 2 drops inside each nasal passage. You need to use the medication twice, three times a day.
- Infants and children under 6 years of age are prescribed a 0.5% solution. 1-2 drops should be instilled inside each nasal passage. You should use the drug 1-2 times per day.
- Do not use the drug more than three times a day. It is important not to exceed the course of treatment for 3 to 5 days.
Side effects
Typically, the drops in question containing xylometazoline are well tolerated by patients. Therefore, they are often used in the treatment of rhinitis in children.
But in rare cases, certain side effects may occur. Adverse events are represented by the following conditions:
- excessive mucus production;
- increased swelling;
- bouts of sneezing;
- burning sensation in the area where the drops were administered (paresthesia);
- dry mucous membranes.
In more rare cases, doctors record the following systemic disorders:
- headache;
- insomnia;
- tachycardia;
- vomit;
- depression;
- promotion blood pressure;
- decreased vision;
- swelling of the nasal mucosa;
- arrhythmia.
Long-term use of Xylen nasal drops can provoke the development of addiction to active substance.
Overdose
In case of overdose with nasal drops, increased side effects. Treatment given state symptomatic, carried out under the supervision of a specialist.
special instructions
Nasal drops are used with caution in the treatment of patients with the following pathologies:
- BPH;
- angina pectoris;
- hyperthyroidism;
- diabetes.
Before instillation, it is necessary to clean the nasal passages.
Missed dose: drops should be used within 1 hour. Then do not use for an hour, the dose cannot be doubled.
The drug in question, in a dosage exceeding that specified in the instructions, can affect the ability to drive a vehicle or engage in any potential dangerous species activities that require speed of psychomotor reactions and concentration.
Drug interactions
The drug must not be used simultaneously with drugs from the following groups:
- monoamine oxidiase inhibitors (Moclobemide, Befol, Iproniazid, Selegelin, Phenelzine);
- tricyclic antidepressants (Elavil, Nortriptyline, Azafen, Clofranil, Amitriptyline).
Xylene is an alpha-adrenergic agonist; a vasoconstrictor intended for topical use in ENT practice.
The use of Xylene leads to a narrowing of the blood vessels of the nasal mucosa and helps to: restore the patency of the nasal passages, eliminate hyperemia (overflow of blood vessels) and swelling of the nasal mucosa, and facilitate nasal breathing.
Action medicine develops quite quickly (within a few minutes after applying the spray or drops), duration – up to 10 hours.
Clinical and pharmacological group
Vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist.
Conditions for dispensing from pharmacies
Dispensed without a doctor's prescription.
Prices
How much does Xylene cost? average price in pharmacies it is at the level of 30 rubles.
Release form and composition
Xylene is produced in the form:
- Nasal 0.05% and 0.1% spray (clear, colorless liquid) containing 500 mcg and 1 mg, respectively, of xylometazoline hydrochloride and excipients: purified water, disodium edetate, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, sodium chloride, benzalkonium chloride. In dark bottles with a spray of 10 ml and 15 ml;
- Nasal 0.05% and 0.1% drops (clear, colorless liquid) containing 1 ml of 500 mcg and 1 mg, respectively, of xylometazoline hydrochloride and auxiliary components: sodium hydrogen phosphate dodecahydrate, benzalkonium chloride, sodium chloride, disodium edetate, potassium dihydrogen phosphate, purified water. In dropper bottles of 10 ml.
Pharmacological effect
The active ingredient of the drug is Xylometazoline hydrochloride. It is an alpha-adrenergic agonist with non-selective action. In small doses it acts on alpha1-adrenergic receptors, in large doses - on alpha2-adrenergic receptors. When in contact with the nasal mucosa, it contracts blood vessels, reduces the intensity of inflammation and exudation. Relieves the nose from redness and swelling. Facilitates breathing through the nose during rhinitis.
When used nasally, Xylometazoline almost does not enter the bloodstream. Well tolerated even in people with highly sensitive nasal mucosa.
Indications for use
Due to its actions, the drug is popular in the treatment of ENT diseases. It is prescribed to both adults and children.
Xylen is usually prescribed for the following diseases:
- in acute form;
- Hay fever;
- Ethmoiditis;
- Sphenoiditis;
- Rhinitis of allergic etiology.
For otitis media, you also need to put drops in your nose, not your ear canals. There is an opinion that Xylene can be used as eye drops, however, the instructions do not include eye diseases as indications; on the contrary, it is not recommended to use the drug for patients with glaucoma.
It is also recommended to use the drug when heavy discharge from the nose and its congestion, which are a sign of various respiratory and viral diseases. Xylene is used after nasal surgery and before certain medical procedures, for example before rhinoscopy.
Contraindications
Absolute:
- Surgical interventions on meninges in the anamnesis;
- Children under 2 years of age - for 0.05% spray, up to 6 years - for 0.1% drops and spray;
- Lactation period (or breastfeeding should be stopped);
- Atrophic rhinitis;
- Expressed arterial hypertension;
- Tachycardia;
- Severe form of atherosclerosis;
- Glaucoma;
- Individual hypersensitivity to xylometazoline or auxiliary components of the drug.
Relative (special care required):
- Diabetes;
- Benign prostatic hyperplasia;
- Cardiac ischemia;
- Hyperthyroidism;
- Pregnancy.
Use during pregnancy and lactation
During pregnancy and lactation it should be used only after a careful assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.
Dosage and method of administration
The instructions for use indicate: Xylene spray and drops are intended for intranasal use. Before each administration of the drug, it is necessary to clear the nasal passages of mucus.
- The minimum interval between applications is 8 hours. The duration of treatment is determined by the attending physician, but it should not exceed 5 days.
- Adults and children over 6 years old – 1-2 drops of 0.1% drops or 1 injection of 0.1% spray into each nasal passage 2-3 times a day;
- Children 2-6 years old - 1-2 drops of 0.05% drops or 1 injection of 0.05% spray into each nasal passage 1-2 times a day;
- Children from birth to 2 years – 1-2 drops of 0.05% drops in each nasal passage 1-2 times a day.
If the patient missed the time of administration of the drug, the dose cannot be doubled during the next procedure.
Side effects
With frequent and/or long-term use of the drug, the following are possible: side effects: irritation of the mucous membrane, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.
Sometimes taking Xylene is accompanied by swelling of the nasal mucosa (more often with long-term use), palpitations, disturbances heart rate, increased blood pressure, headache, vomiting, sleep disturbance, visual impairment.
With prolonged use in high doses, depression may occur.
Overdose
Cases of drug overdose occur in rare cases when the recommended dose is followed. With uncontrolled use of nasal drops and use of the drug for more than 14 days, the patient experiences systemic signs overdose:
- Pain in the temples and back of the head;
- Increased blood pressure;
- Depressive disorders;
- Constant drowsiness and apathy to what is happening;
- Lethargy and fatigue;
- Dizziness;
- Increased side effects described above.
With the development of such clinical symptoms the patient should immediately stop taking the drug and consult a doctor. If necessary, treatment is provided to eliminate the symptoms of overdose.
special instructions
Should not be used for long periods of time, e.g. chronic rhinitis. At colds in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.
Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).
Drug interactions
Incompatible with MAO inhibitors and tricyclic antidepressants.
Xylene is an alpha-adrenergic agonist; a vasoconstrictor intended for topical use in ENT practice.
Release form and composition
Dosage forms of Xylene:
- Nasal drops 0.05% and 0.1% (10 ml each in polymer or dark glass bottles with a dropper attachment, 1 bottle in cardboard packs);
- Nasal spray 0.05% and 0.1% (10 ml each in polymer or dark glass bottles with a dropper attachment, 1 bottle in cardboard packs).
The active ingredient of the drug is xylometazoline hydrochloride: in 1 ml of 0.05% drops and spray - 0.5 mg, in 1 ml of 0.1% drops and spray - 1 mg.
Indications for use
- Symptomatic treatment of sinusitis and acute rhinitis of various etiologies, incl. rhinitis in acute respiratory diseases and allergic rhinitis;
- Reducing swelling of the nasopharynx with otitis media;
- Prophylactic use in preparation for diagnostic procedures in the nasopharynx, in particular rhinoscopy.
Contraindications
Absolute:
- Atrophic rhinitis;
- Severe arterial hypertension;
- Tachycardia;
- Severe form of atherosclerosis;
- Glaucoma;
- History of surgical interventions on the meninges;
- Children under 2 years of age - for 0.05% spray, up to 6 years - for 0.1% drops and spray;
- Lactation period (or breastfeeding should be stopped);
- Individual hypersensitivity to xylometazoline or auxiliary components of the drug.
Relative (special care required):
- Cardiac ischemia;
- Hyperthyroidism;
- Diabetes;
- Benign prostatic hyperplasia;
- Pregnancy.
Directions for use and dosage
Both dosage forms of Xylene are intended for intranasal use. Before each administration of the drug, it is necessary to clear the nasal passages of mucus.
- Adults and children over 6 years old – 1-2 drops of 0.1% drops or 1 injection of 0.1% spray into each nasal passage 2-3 times a day;
- Children 2-6 years old - 1-2 drops of 0.05% drops or 1 injection of 0.05% spray into each nasal passage 1-2 times a day;
- Children from birth to 2 years – 1-2 drops of 0.05% drops in each nasal passage 1-2 times a day.
The minimum interval between applications is 8 hours.
The duration of treatment is determined by the attending physician, but it should not exceed 5 days.
If the patient missed the time of administration of the drug, the dose cannot be doubled during the next procedure.
Side effects
In general, Xylene is well tolerated. Adverse reactions are usually observed with frequent use drug or administration of high doses.
Possible side effects: dryness and irritation of the nasopharyngeal mucosa, sneezing, hypersecretion, paresthesia, tachycardia, palpitations, arterial hypertension; in isolated cases - swelling of the nasal mucosa, headaches, insomnia, decreased visual acuity, arrhythmias, depressive states.
At long-term treatment(more than 5 days), swelling of the nasal mucosa and atrophic rhinitis may develop.
When using excessive doses, there is a possibility of developing systemic side effects characteristic of xylometazoline, such as paresthesia, blood pressure lability, tachycardia, and convulsions. There is no specific antidote for the drug. In case of overdose, Xylen should be discontinued and symptomatic therapy and activities aimed at maintaining the function of the cardiovascular system.
special instructions
Xylene is not intended for the treatment of chronic rhinitis.
During pregnancy, xylometazoline is prescribed only in extreme cases. However, it should be used in minimal doses for no more than 3 days in a row.
After each instillation, it is necessary to clean the dropper and tightly close the bottle with a lid.
Drug interactions
For patients receiving monoamine oxidase inhibitors, xylometazoline can be used no earlier than 2 weeks after their discontinuation.
Xylene should not be used during treatment with tricyclic antidepressants.
Terms and conditions of storage
Store in original packaging at a temperature of 15 to 25 ºС.
Shelf life – 3 years.
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In this article you can find instructions for use medicinal product Xylene. Feedback from site visitors - consumers - is presented of this medicine, as well as the opinions of specialist doctors on the use of Xylene in their practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Xylene, if available structural analogues. Use for the treatment of allergic rhinitis and sinusitis in adults, children, as well as during pregnancy and lactation. Composition and addiction to the drug with long-term use.
Xylene- a vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist. When applied to the mucous membranes, it causes vasoconstriction, as a result of which local hyperemia and swelling are reduced. For rhinitis, it facilitates nasal breathing.
Compound
Xylometazoline hydrochloride + excipients.
Pharmacokinetics
At local application practically not absorbed, plasma concentrations are so low that they cannot be determined by modern analytical methods.
Indications
- acute allergic rhinitis;
- sinusitis (sinusitis);
- hay fever;
- otitis media (to reduce swelling of the nasopharyngeal mucosa);
- preparing the patient for diagnostic procedures in the nasal passages.
Release forms
Nasal drops 0.05% and 0.1%.
Nasal spray 0.05% and 0.1%.
Instructions for use and dosage regimen
Apply topically for 7-14 days. The dose depends on the one used dosage form and the patient's age.
Side effect
- irritation of the mucous membrane, burning, tingling;
- sneeze;
- dry nasal mucous membranes;
- hypersecretion;
- swelling of the nasal mucosa (more often with long-term use);
- heartbeat;
- heart rhythm disturbances;
- increased blood pressure;
- headache;
- vomit;
- sleep disorders;
- visual impairment;
- depressive state.
Contraindications
- angle-closure glaucoma;
- atrophic rhinitis;
- arterial hypertension;
- tachycardia;
- severe atherosclerosis;
- hyperthyroidism;
- surgical interventions on the meninges (in history);
- increased sensitivity to xylometazoline.
Use during pregnancy and breastfeeding
During pregnancy and lactation, it should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.
Use in children
Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).
special instructions
It should not be used for a long time, for example, with chronic rhinitis, as addiction or dependence may develop. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.
Drug interactions
Incompatible with MAO inhibitors and tricyclic antidepressants.
Analogues of the drug Xylen
Structural analogues of the active substance:
- Brizolin;
- Galazolin;
- Grippostad Reno;
- For nose;
- Dr. Theiss Nazolin;
- Dr. Theiss Rhinotheiss;
- Asterisk NOZ;
- Influrin;
- Xylobene;
- Xylometazoline;
- Xymelin;
- Xymelin Eco with menthol;
- Nosolin;
- Nosolin balm;
- Olint;
- Otrivin;
- Rinomaris;
- Rhinonorm;
- Rhinorus;
- Rhinostop;
- Sanorin Xylo;
- Sialor;
- Snoop;
- Suprima NOZ;
- Tizin Xylo;
- Tizin Xylo Bio;
- Farmazolin;
- Eucazoline Aqua;
- Espazolin.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
Active substance
Xylometazoline hydrochloride belongs to the group of alpha-adrenergic agonists. It affects a certain type of vascular receptors (alpha receptors), producing a narrowing of the bloodstream. In the pathogenesis of the runny nose this has great value: by reducing the lumen of the capillaries, xylometazoline impairs the nutrition of the mucous membrane, it becomes anemic and stops producing mucus. Thus, the drug reduces the amount of secretion and relieves swelling (nasal congestion).
Xylometazoline is a medium-acting decongestant. Its activity lasts for 6-8 hours. After this, repeated administration of the drug dose is required. In addition, with prolonged use of drops of this type, addiction develops. Receptors stop perceiving the substance, and to achieve the necessary therapeutic effect a high dose of the drug is required.
When any decongestants are discontinued, rebound syndrome may develop. The secretion of mucous secretion increases several times, reminiscent of the return of the disease. However, it should be remembered that this is just vascular reaction. At correct use drops it does not appear.
Use of the drug
Nasal drops have quite wide range its application, namely:
- treatment of runny nose. There are rhinitis different types, and their reasons can be the most various factors. The drug fights all these types, including hay rhinitis;
- fight against polyps;
- treatment of sinusitis, including sinusitis;
- as a remedy against allergic manifestations;
- additional treatment for otitis media, in which it is necessary to relieve swelling of the nasopharynx.
Xylene is an exclusively intranasal drug, that is, the product is used for instillation into the nose
Among other things, nasal drops are also used for diagnostic study nasal passages, in particular during rhinoscopic examination.
It is important to understand that the product must be used correctly, otherwise the effectiveness will suffer. So, before you instill the nasal passages, nasal cavity should be cleared of mucous secretion, this will allow the drug to better penetrate the nasal mucosa
Some patients abuse the use of the drug, forgetting about correct dosages. As mentioned above, the product lasts for about ten hours, so the interval between instillations should be at least eight to ten hours. In addition, if the duration of treatment with this drug exceeds a week, this may negatively affect the condition of the mucous membrane of the nasal cavity, including the development of atrophic changes.
However, the exact dosage regimen and duration of treatment are prescribed by a specialist, taking into account the individual characteristics of the patient.
Considering the modern rhythm of people's lives, it is possible that the patient may simply forget to put drops in his nose. In this case, you should not during next appointment double the dosage.
Treatment with xylene should last no more than five days
Release form
Manufacturers produce Xylene in several forms. The patient chooses the most suitable one.
Drops
This form will please supporters of traditional medicines. The percentage of the main component (xylometazoline hydrochloride) is 0.1 or 0.05. To increase efficiency, the active component is supplemented:
- benzalkonium chloride;
- purified water;
- disodium edetate;
- sodium hydrogen phosphate dodecahydrate.
Drops are poured into glass vials with a dropper or elastic plastic containers with a dispenser. The retail chain receives a typical package of 10 ml. A cardboard box contains 1 bottle and instructions.
Spray
This option is preferred by people who value ease of use. The percentage of the main component (xylometazoline hydrochloride) is 0.1 and 0.05. In the form of a spray, the active substance is supplemented with:
- sodium chloride;
- potassium dihydrogen phosphate;
- sodium hydrogen phosphate dodecahydrate;
- disodium edetate dihydrate;
- purified water.
The medicine is poured into elastic plastic vials and packaged (along with instructions and a spray nozzle) in cardboard.
Nasal gel
Not a very common medication option. It is chosen quite rarely. It helps well in treating children over seven years of age and adults.
Instructions for use - Xylen neo
Release form
Nasal spray with camphor and menthol aroma in the form of an opaque, white, gel-like or liquid mass with a very faint odor of camphor and menthol and thixotropic properties (thickens at rest and liquefies when shaken), which is located in a bottle sealed with a dosing pump, equipped with a spray nozzle with a protective cap; the drug is dispensed from the bottle through a spray nozzle in the form of an aerosol cloud, which is particles of a viscous liquid dispersed in a gaseous environment.
Excipients: benzyl alcohol - 0.25 g, benzalkonium chloride - 0.01 g, disodium edetate dihydrate (Trilon B) - 0.015 g, racemic camphor - 0.005 g, levomenthol - 0.008 g, povidone K17 - 0.25 g, microcrystalline cellulose - 4 g, sodium carmellose - 4 g, macrogol 400 - 21.5 g, sodium dihydrogen phosphate dihydrate - 0.75 g, disodium hydrogen phosphate dodecahydrate - 0.15 g, purified water - up to 100 g.
Apply topically for 7-14 days. The dose depends on the dosage form used and the age of the patient.
Indications for use
Acute allergic rhinitis, sinusitis, hay fever, otitis media (to reduce swelling of the nasopharyngeal mucosa), preparing the patient for diagnostic procedures in the nasal passages.
Pregnancy and Lactation
During pregnancy and lactation, it should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.
Use in children
Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).
Pharmacodynamics
Vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist. When applied to the mucous membranes, it causes vasoconstriction, as a result of which local hyperemia and swelling are reduced. For rhinitis, it facilitates nasal breathing.
Pharmacokinetics
When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.
With frequent and/or long-term use: irritation of the mucous membrane, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.
Rarely: swelling of the nasal mucosa (more often with long-term use), palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disorders, visual disturbances.
With long-term use in high doses: depressive state.
Contraindications
Angle-closure glaucoma, atrophic rhinitis, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, surgical interventions on the meninges (history), hypersensitivity to xylometazoline.
Interaction with other drugs
Incompatible with MAO inhibitors and tricyclic antidepressants.
special instructions
Should not be used for a long time, for example, for chronic rhinitis. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.
Use in pediatrics
Xylometazoline should be prescribed with caution to children under 2 years of age (gel – up to 7 years of age)
Storage conditions
At a temperature of 15-25 degrees (do not refrigerate, do not freeze)
Best before date
Xylen neo spray - VEROPHARM, instructions for use, drug analogues - MedZai.net
Instructions for use and dosage
“Xylene” is great for nasal congestion. But for successful treatment You should strictly follow your doctor's recommendations. The treatment regimen should be developed individually in each case.
The drug should come into free contact with the irritated mucosa. Before using the medicine, it is recommended to clear the nasal cavity of mucus. It needs to be blown off or washed off.
It is important to prevent an overdose: if you skip the use of the drug, it is forbidden to shorten the intervals and increase subsequent injections.
The total duration of use of the drug is no more than a week. It must not be exceeded to prevent negative effects.
For children
Babies are allowed to be treated with spray and drops after they reach 2 years of age. General rules must be followed:
- For children 2-6 years old, it is recommended to instill 1-2 drops into each nostril 1-2 times a day. When treating with a spray, you need to spray 1 spray into each nostril 1-2 times a day.
- For children over 6 years old, it is permissible to instill 1-2 drops into each nostril 2-3 times a day.
- When using the spray, you need to do 1 injection into each nostril 2-3 times a day.
- Nasal gel is used to treat children over 7 years of age. It is recommended to place the drug in each nostril as deeply as possible. Carry out the procedure 3-4 times a day.
Adults
All three forms of Xylene are used to treat adult patients. When using drops, you need to instill 1-2 drops of medicine into each nostril 2-3 times a day.
Nasal gel is placed 3-4 times a day in each nostril. The gel should penetrate as deeply as possible.
When treating with a spray, you need to do 1 injection into each nostril 2-3 times a day.
Nuances of use during pregnancy
Women expecting the birth of a baby are allowed to take medicine only as prescribed by a doctor. It is recommended to strictly follow the rules of admission. Expectant mothers are allowed to use the medicine for no more than 3 days.
Side effects
Like any other drug, Xylen has been tested for adverse reactions. As a rule, they appear during prolonged use of the drug or when the dosage is exceeded.
Among the most obvious side effects, experts say irritation in the nose, a burning or tingling effect, sneezing or increased discharge.
It happens that after long-term use the nasal mucosa, on the contrary, dries out excessively or appears severe swelling making breathing difficult.
In some cases, doctors assume the occurrence of systemic disorders, such as:
- arrhythmia,
- increased heart rate,
- headache,
- increase in blood pressure,
- sleep disturbance,
- decreased vigilance;
- influence on the central nervous system,
- depression.
In all of the above cases, you must immediately stop taking the medication and consult your doctor. The otolaryngologist must stop taking the drug, change treatment, or prescribe a new medication.
Features of the drug
Xylometazoline is the main component of the drug. After contact with the mucous membrane of the nasal cavity, it narrows the blood vessels. This results in significantly reduced swelling and redness. How is this noticeable to the patient? Breathing is restored and made easier, and the hated congestion, which prevents you from sleeping at night and from doing everyday activities during the day, goes away.
As for the speed of the effect, these nasal drops already have an effect about five minutes after instillation. therapeutic effect. One of the advantages of the drug is that it retains its effect for ten hours.
I would like to separately note that the drug is not absorbed into the bloodstream, but when using large dosages this is possible. As a result, a systemic effect will be exerted on the entire body as a whole.
Use in childhood
Children's age is not a contraindication to the use of the drug Xylene. In children from birth to 3 years, it is better to use a drop form of the solution. The concentration of the finished drug is 0.05%. Only this dilution is used in children.
After 2 years you can use the spray. For children from 2 to 6 years old, 1-2 injections of a 0.05% solution are given per day. In children over 6 years of age, a 0.1% spray can be used 2-3 times a day.
On pharmaceutical market There are many drugs that are used to treat various otolaryngological diseases in children. These are various aerosols, drops, gels, solutions. One of effective drugs considered Xylene. This medicine in the form of a spray or nasal drops belongs to the group, so it quickly helps eliminate many symptoms of ENT diseases.
However, it is important to know the specifics of using Xylene in childhood. This will help prevent the development of side effects, as well as avoid cases of overdose. Xylene contains xylometazoline hydrochloride, which is active substance medicines
The auxiliary components of the drug include:
Xylene contains xylometazoline hydrochloride, which is the active substance of the drug. The auxiliary components of the drug include:
- Sodium hydrogen phosphate
- Potassium dihydrogen orthophosphate
- Trialon B
- Benzalkonium chloride
- Sodium chloride
- Purified water
The combination of these substances in Xylene has vasoconstrictor properties. Thanks to this, it has the following effects on the body:
- Prevents swelling of the nasal mucosa.
- Reduces hyperemia.
- Eliminates nasal congestion.
- Facilitates nasal breathing.
- Helps reduce rhinorrhea.
These properties are indispensable in the treatment of otolaryngological pathologies, therefore they are often prescribed in ENT practice.
It is important to say that the effect of using the drug is observed after about five minutes and lasts up to ten hours.
In pharmacies you can buy Xylen in the following two forms:
- Nasal drops
- Spray for intranasal use
Depending on the age of patients it is intended for, the content of the active component in the drug is different. For children under six years of age, Xylen is prescribed at 0.05 percent.
The instructions indicate that Xylene is good for three years from the date of manufacture. Then the medicine loses its properties and has no therapeutic effect.
When is Xylen prescribed to children?
Due to its actions, the drug is popular in the treatment of ENT diseases. It is prescribed to both adults and children.
Xylen is usually prescribed in childhood for the following diseases:
- in acute form
- Hay fever
- Sphenoiditis
- Rhinitis of allergic etiology
For otitis media, you also need to put drops in your nose, not your ear canals. There is an opinion that Xylen can be used as eye drops, but the instructions do not include eye diseases as an indication; on the contrary, it is not recommended to use the drug for patients with glaucoma.
It is also recommended to use the drug for heavy discharge from the nose and nose, which is a sign of various respiratory and viral diseases.
Xylene is used after nasal surgery and before certain medical procedures, such as rhinoscopy.
Dosage and application features
Xylene is used only intranasally.
0.1 percent nasal drops are used to treat patients aged six years and older. The recommended dosage in this case is one to two drops in each nasal passage up to three times a day.
If Xylene is used in the form of a spray to treat a runny nose, then one injection into each nostril will be sufficient. The interval between doses should be at least eight hours. A 0.05 percent spray is used one to two times a day.
The maximum duration of treatment is up to a week in adults. Children should be treated with Xylen for no longer than five days. This is explained by the fact that the drug can provoke addiction, which may result in the development of undesirable health consequences.
A special feature of nasal instillation with Xylen is preparation for the procedure. To do this, you must first clear the nasal passages of secretions.
Therefore, it is important to blow your nose before using nasal drops, and then rinse. You can rinse your nose with a salt solution you prepare yourself.
The pharmacy also sells products for this procedure based on sea water: Physiomer, Humer and others.
Nasal drops have a number of restrictions for use. Patients who suffer from the following diseases are not allowed to use the product:
- Atherosclerosis in an advanced stage
- Hypertension
- Glaucoma of various origins
- Atrophic rhinitis
- Tachycardia
A contraindication to the use of Xylene is individual hypersensitivity to any components of the drug. Also, drops are not prescribed to patients who have undergone surgical interventions affecting the lining of the brain.
Due to the incompatibility of the drug with antidepressants, as well as with monoamine oxidase inhibitors, Xylene is not prescribed for simultaneous treatment with drugs of this group
The interval between therapy with these drugs should be at least fourteen days.
Caution when using this medication is important for people who have a history of diabetes mellitus, angina pectoris, hyperthyroidism and prostate adenoma.
Possible adverse reactions and overdose
Typically, Xylen nasal drops are tolerated normally by patients. But sometimes if the rules of use are violated, the following side effects may occur:
- Dry mucous membranes
- Sneezing
- Increased swelling
- Copious mucous discharge
- Burning and tingling sensation in the area where the drug was injected
- Sleep disorder
In rare cases, organ system disorders occur. These include migraine, high pressure, arrhythmia, decreased vision, tachycardia, depression, vomiting. Typically, such phenomena are observed when the instructions for use of Xylene are not followed (exceeding the dose and amount of daily use).
An overdose is possible when the dosage and daily amount of drops or spray are violated during treatment. TO possible phenomena overdoses include:
- Blood pressure instability
- Convulsions
- Development of depression
- Increased heart rate
More information on how to treat a runny nose in a child can be found in the video:
There is no specific antidote to the drug substances. In order to eliminate such reactions, you need to contact a specialist. Usually in such cases he will prescribe remedies that eliminate these symptoms. Often these are drugs that stabilize the functioning of blood vessels and the heart.
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