Solution for intramuscular and subcutaneous injection colorless transparent liquid.
Suppositories for rectal administration are uniform suppositories from white to white with a yellowish sheen, torpedo-shaped. A weak specific odor is allowed.
Spray for nasal use, dosed transparent, or slightly opalescent, colorless, or slightly yellowish liquid. A weak specific odor is allowed.
Solution for intramuscular and subcutaneous administration in a blister strip packaging 5 or 10 ampoules in a cardboard box 1 or 2 packages.
Suppositories for rectal use in a blister strip packaging 5 or 10 pcs. in a pack of cardboard 1 or 2 packages.
Spray for nasal use dosed in a plastic bottle with a dosing device 8.5 ml in a cardboard box 1 bottle.
Composition and active substance
The composition of Imunofan includes: Solution for intramuscular and subcutaneous administration 1 ml imunofan 50 mcg Excipients: sodium glycine chloride water for injection Rectal suppositories 1 supp. imunofan 100 mcg excipients: purified water glycine solid fat tween 80
in a contour acheikova packing 5 or 10 pcs. in a pack of cardboard 1 or 2 packages.
Spray for nasal administration, dosed 1 dose of imunofan 50 mcg excipients: sodium chloride benzalkonium chloride sodium glycine edetate (Trilon B) purified water
pharmachologic effect
The drug has an immunoregulatory, detoxifying, hepatoprotective effect and causes inactivation of free radical and peroxide compounds. pharmachologic effect based on the achievement of three main effects: correction of the immune system, restoration of the balance of the oxidative-antioxidant reaction of the body and inhibition of multiple drug resistance protein-mediated transmembrane transport pump of the cell.
The effect of the drug begins to develop within 2-3 hours (fast phase) and lasts up to 4 months (medium and slow phases).
During fast phase(duration - up to 2-3 days), first of all, the detoxification effect is manifested - it increases antioxidant protection organism by stimulating the production of ceruloplasmin, lactoferrin, catalase activity, the drug normalizes lipid peroxidation, inhibits the breakdown of cell membrane phospholipids and the synthesis of arachidonic acid, followed by a decrease in blood cholesterol and the production of inflammatory mediators.
In case of toxic and infectious liver damage, the drug prevents cytolysis, reduces the activity of transaminases (AST, ALT) and the content of bilirubin in the blood serum.
During the middle phase (starts after 2-3 days, duration - up to 7-10 days), there is an increase in the reactions of phagocytosis and death of intracellular bacteria and viruses.
During the slow phase (begins to develop on days 7-10, duration up to 4 months), the immunoregulatory effect of Imunofan is manifested - the restoration of disturbed parameters of cellular and humoral immunity. During this period, the normalization of the immuno-regulatory index is observed, an increase in the production of specific antiviral and antibacterial antibodies is noted, which is equivalent to the action of some therapeutic vaccines. Unlike recent drug does not significantly affect the production of reagin antibodies of the IgE class and does not enhance the hypersensitivity reaction immediate type Imunofan stimulates the formation of IgA in congenital insufficiency.
Imunofan effectively suppresses multidrug resistance of tumor cells and increases their sensitivity to the action of cytostatic drugs.
What Imunofan helps from: testimony
Prevention and treatment in adults and children over two years of age:
- Immunodeficiency and toxic conditions.
- Chronic inflammatory diseases of various etiology.
Contraindications
- Hypersensitivity
- Pregnancy complicated by Rh-conflict
- Children up to age 2 years.
Imunofan during pregnancy and breastfeeding
Due to insufficient knowledge, it should be used with caution during pregnancy and lactation.
Imunofan: instructions for use
Dosed spray for nasal administration. Intranasally.
When using, the bottle should be held vertically, with the spray up.
1 dose of the drug contains 50 mcg of Imunofan. The daily dose should not exceed 200 mcg.
- V complex therapy acute and chronic infectious and inflammatory diseases accompanied by symptoms of intoxication and immunodeficiency
Assign 1 dose (50 mcg) in each nasal passage 2 times a day, daily for 10-15 days.
1 dose (50 mcg) in each nasal passage 2 times a day, daily, the course of treatment is 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.
1 dose (50 mcg) in each nasal passage once a day, daily, the course of treatment is 10-15 days, to prevent relapse, repeated courses should be carried out in 4-6 months.
- In the treatment regimen for patients with HIV infection
1 dose (50 mcg) in each nasal passage 1 time a day, every day, for 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.
1 dose (50 mcg) in each nasal passage once a day, every day, for 8-10 days before chemo-radiation therapy and surgery, followed by continuation of the course during the entire period of treatment.
- In patients with widespread tumor process(III-IV stages) different localization in terms of complex or symptomatic therapy
1 dose (50 mcg) in each nasal passage 1 time a day, daily, for 8-10 days. If necessary and in the presence of pronounced symptoms of toxicosis, it is recommended to repeat the course.
Suppositories for rectal administration. Rectally. Single dose and daily - 100 μg (0.1 mg) 1 suppository.
- In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and surgery)
Once daily, the course of treatment is 8-10 suppositories before chemo-radiation therapy and surgery, followed by continuation of the course throughout the entire period of treatment.
- In patients with a widespread tumor process (stage III - IV) of various localization in the form of complex or symptomatic therapy
Once, daily, the course of treatment is 8-10 suppositories, with a break of 15-20 days and repetition of courses during the entire period of subsequent treatment.
Once a day, daily, a course of treatment is 10-20 suppositories. The appointment of the drug should be carried out during the entire course of chemotherapy and radiation therapy and after the end of the course to prevent the development of toxicosis.
- In the complex therapy of children with papilomatosis of the larynx and oropharynx
Once a day, daily, a course of treatment is 10 suppositories.
- With opportunistic infections (cytomegalovirus and herpes infection, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis)
Once a day, daily, the course of treatment is 15 - 20 suppositories. If necessary, repeated courses should be carried out in 2-4 weeks.
- With chronic viral hepatitis and chronic brucellosis
Once a day, every day, the course of treatment is 15 - 20 suppositories; to prevent relapse, repeated courses should be carried out in 2 - 3 months.
- With diphtheria
Once a day, daily, the course of treatment is 8-10 suppositories. In case of diphtheria bacteriocarrier - once every 3 days - 3-5 suppositories.
Once a day, every day, the course of treatment is 7-10 suppositories, if necessary, the course of the drug should be continued up to 20 suppositories.
- With broncho-obstructive syndrome, cholecystopancreatitis, rheumatoid arthritis
Once every 3 days, the course of treatment is 8-10 suppositories, if necessary, the course should be continued up to 20 suppositories with the same interval.
- In the treatment of psoriasis
Once a day, daily, the course of treatment is 15 - 20 suppositories.
Once a day of vaccination.
Solution for intramuscular and subcutaneous administration. Imunofan is prescribed subcutaneously or intramuscularly, in courses. One-time and daily dose- 50 mcg.
- In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and surgery)
Once, daily, a course of treatment of 8-10 injections before chemo-radiation therapy and surgery, followed by continuation of the course throughout the entire period of treatment.
- In patients with a widespread tumor process ( III-IV stages) of various localization in the form of complex or symptomatic therapy
Once, daily, the course of treatment is 8-10 injections, with a break of 15-20 days and repetition of courses during the entire period of subsequent treatment.
- In children with malignant diseases hematopoietic and lymphoid tissue
Once a day, daily, a course of treatment is 10-20 injections. The appointment of the drug should be carried out during the entire course of chemotherapy and radiation therapy and after the end of the course to prevent the development of toxicosis.
- In the complex therapy of children with papplomatosis of the larynx and oropharynx
1 time a day, daily, the course of treatment is 10 injections.
- With opportunistic infections (cytomegalovirus and herpes infection, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis)
- In the complex therapy of HIV infection
Once a day, daily, the course of treatment is 15-20 injections.
- For chronic viral hepatitis and chronic brucellosis
Once a day, every day, the course of treatment is 15-20 injections, to prevent relapse, repeated courses should be carried out in 2-3 months.
- With diphtheria
Once a day, daily, the course of treatment is 8-10 injections. With diphtheria bacterium - 1 time every 3 days - 3-5 injections.
- In the treatment of III-IV degree burns with symptoms of toxemia, septicotoxemia, in surgical patients with septic endocarditis, for a long time non-healing wounds extremities, purulent-septic complications
Once a day, every day, the course of treatment is 7-10 injections, if necessary, the course of the drug should be continued up to 20 injections.
- With broncho-obstructive syndrome, cholecystopancreatitis, rheumatoid arthritis
Once every 3 days, the course of treatment is 8-10 injections, if necessary, the course should be continued up to 20 injections with the same interval.
- In the treatment of psoriasis
1 - once a day, daily, the course of treatment is 15-20 injections.
- In the complex therapy of adults and children with inflammatory eye diseases
In case of damage to the anterior parts of the eye (keratitis, keratouveitis) 0.5 ml subconjunctivally or in combination with intramuscular injection, 1 time per day every day, the course of treatment is 7-10 injections.
With damage to the predominantly posterior parts of the eye (peripheral, posterior uveitis, retinovasculitis) and generalized inflammatory processes 0.5 - 1.0 ml parabulbarly in combination with intramuscular injection, once a day, daily, the course of treatment is 15-20 injections.
- In adults in the vaccine prophylaxis regimen
Once a day of vaccination.
Side effects
Perhaps: individual intolerance, allergic reactions.
special instructions
As a result of the activation of phagocytosis, a short-term exacerbation of foci is possible. chronic inflammation supported by the persistence of viral or bacterial antigens.
Compatibility with other drugs
Not described.
Overdose
Not described.
Storage conditions and shelf life
The drug is stored in a dark place at a temperature of 2 ° C to 10 ° C, out of the reach of children. It is not recommended to use the drug after the expiry date indicated on the package.
Imunofan is a domestic original immunostimulant. It has an immunomodulatory and detoxifying effect, has a positive effect on liver function, and neutralizes aggressive free radicals. The human immune system throughout the life of its "owner" has to regularly take on challenges from a host of adverse factors environment: these are bacterial and viral agents, poor ecology, poor quality food, exhausting physical labor, emotional stress, excessive drug load, bad habits... To do this, she sometimes needs a certain pharmacological "feed". A real breakthrough in the treatment and prevention of disorders immune system was the opening peptide hormones immunity produced by the thymus ( thymus). This motivated scientists to search for new peptide drugs that act on inflammatory mediators and the system of neutralizing free radicals. Imunofan is a representative of a new generation of immune peptides. Its action develops in three directions: correction immune status, restoration of redox balance internal environment organism and suppression of multiple drug tolerance, mediated by transport pump proteins located in cell membranes. In the action of imunofan, a fast (from the first 2-3 hours to 2-3 days), medium and slow (up to 4 months) phases are distinguished. During the fast phase, the drug shows, first of all, its detoxifying effect: the synthesis of multifunctional glycoproteins (lactoferrin and ceruloplasmin) is stimulated, the primary antioxidant enzyme catalase is activated. Imunofan regulates the course of fat peroxidation reactions, inhibits the destruction of membrane phospholipids, inhibits the synthesis of arachidonic acid, as a result of which the plasma cholesterol content decreases and the synthesis of prostaglandin inflammation mediators is inhibited. During the middle phase, which lasts up to 7-10 days, there is an activation of phagocytic reactions and the death of intracellular pathogens - bacteria and viruses.
In the slow phase, the immunomodulatory effect of Imunofan begins to manifest itself with complete or partial restoration of tissue and humoral immunity indicators: the immunoregulatory index returns to the "pre-crisis" level, the formation of specific immunoglobulins increases. The effect of the drug on the production of antibacterial and antiviral antibodies can be compared with the effect of therapeutic vaccines. Imunofan is also in demand in complex treatment. oncological diseases: it increases the sensitivity of cells cancerous tumor to the action of chemotherapy drugs.
Imunofan is available as a nasal spray. When injecting the drug into the nose, the bottle (as well as the head) must be kept strictly vertical. Before first use, press the wide rim of the nozzle 3-4 times to fill the metering pump. One dose contains 50 mcg active substance drug. The maximum daily dose is 200 mcg. The scope of application of the drug is by no means limited to complex treatment for the prevention of viral and bacterial infections(although, it should be admitted that it is in demand for the most part in this direction). Thus, a pronounced clinical effect from the use of Imunofan was observed in patients with chronic hepatitis B, AIDS marker diseases. The drug has shown itself well in the combined treatment of the gastrointestinal form of salmonellosis: when used in acute phase infections managed to mitigate and shorten the duration of the manifestation of symptoms of intoxication, normalize stool and provide quick removal pathogen. Imunofan can be successfully used for diphtheria, a number of ophthalmic diseases. In some sources, it was mentioned about the effectiveness of the drug in patients with psoriasis, in whom, against the background of pharmacotherapy, the total duration of treatment was reduced, the remission period increased and the subjective state improved.
Pharmacology
The drug has an immunoregulatory, detoxifying, hepatoprotective effect and causes inactivation of free radical and peroxide compounds. The pharmacological action is based on the achievement of 3 main effects: correction of the immune system, restoration of the balance of the oxidative-antioxidative reaction of the body and inhibition of multidrug resistance mediated by proteins of the transmembrane transport pump of the cell.
The effect of the drug begins to develop within 2-3 hours (fast phase) and lasts up to 4 months (medium and slow phases).
During the fast phase (duration - up to 2-3 days), first of all, a detoxification effect is manifested - the antioxidant defense of the body is enhanced by stimulating the production of ceruloplasmin, lactoferrin, catalase activity; the drug normalizes lipid peroxidation, inhibits the breakdown of cell membrane phospholipids and the synthesis of arachidonic acid, followed by a decrease in blood cholesterol levels and the production of inflammatory mediators. In case of toxic and infectious liver damage, the drug prevents cytolysis, reduces the activity of transaminases and the level of bilirubin in the blood serum.
During the middle phase (starts after 2-3 days, duration - up to 7-10 days), there is an increase in the reactions of phagocytosis and death of intracellular bacteria and viruses.
During the slow phase (it begins to develop on days 7-10, duration up to 4 months), the immunoregulatory effect of the drug is manifested - the restoration of disturbed parameters of cellular and humoral immunity. During this period, there is a restoration of the immunoregulatory index, an increase in the production of specific antibodies is noted. The effect of the drug on the production of specific antiviral and antibacterial antibodies is equivalent to the effect of therapeutic vaccines. Unlike the latter, the drug does not significantly affect the production of reaginic antibodies of the IgE class and does not enhance the reaction hypersensitivity immediate type. Imunofan stimulates the formation of IgA in congenital insufficiency.
Imunofan effectively suppresses multidrug resistance of tumor cells and increases their sensitivity to the action of chemotherapeutic drugs.
Release form
40 doses - plastic bottles with a dosing device (1) - cardboard packs.
Dosage
Intranasally. When using, the bottle should be held vertically, with the spray up. Remove the protective cap from the sprayer. Before the first use, fill the dosing pump by pressing the wide rim of the sprayer 3-4 times. Insert the nebulizer into the nasal passage with the head upright. Press the wide rim of the spray gun once until it stops. One dose of the drug contains 50 mcg of Imunofan. The daily dose should not exceed 200 mcg.
In the complex therapy of acute and chronic infectious and inflammatory diseases, accompanied by symptoms of intoxication and an immunodeficiency state, Imunofan is prescribed 1 dose (50 μg) in each nasal passage 2 times / day, daily for 10-15 days.
With opportunistic infections (cytomegalovirus and herpes infection, toxoplasmosis, chlamydia, pneumocystosis, cryptosporidiosis):
- 1 dose (50 mcg) in each nasal passage 2 times / day, daily, course of treatment 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.
For chronic viral hepatitis and chronic brucellosis:
- 1 dose (50 mcg) in each nasal passage 1 time / day, daily, the course of treatment is 10-15 days, to prevent relapse, repeated courses should be carried out after 4-6 months.
In the treatment regimen for patients with HIV infection:
- 1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.
In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiation therapy and operations):
- 1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 8-10 days before chemo-radiation therapy and surgery, followed by continuation of the course during the entire period of treatment.
In patients with a widespread tumor process (stage III-IV) of various localization in terms of complex or symptomatic therapy:
- 1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 8-10 days. If necessary and in the presence of pronounced symptoms of toxicosis, it is recommended to repeat the course.
Interaction
Increases the effectiveness of other types drug therapy: the use of Imunofan helps to overcome resistance to GCS therapy. The appointment of Imunofan is possible in combination with GCS and NSAIDs.
Side effects
Individual intolerance is possible.
Imunofan is an immunomodulator ( regulates the immune system), which has immunostimulating, detoxifying, antioxidant ( antioxidant) and hepatoprotective action ( protects liver cells). It belongs to the synthetic derivatives of thymopoietin. This drug does not have a direct therapeutic effect and is prescribed only in order to increase the body's immunity in various diseases.Types of medication, commercial names of analogues, release forms
Imunofan as medicine that stimulates immunity, does not have commercial counterparts both abroad and on the territory Russian Federation... This drug is produced by only one Russian pharmaceutical company.Forms of drug release
| Company manufacturer | The commercial name of the drug | The country | Release form | Dosage |
| Bionox NPP | Imunofan | Russia | Solution for injections | Maximum daily ( one-time) The dose for adults and children should be 50 micrograms. The doctor prescribes injections in courses of 7 - 20 injections, between which breaks must necessarily follow. The duration of the pauses and the number of injections depend on the type and severity of the pathology. |
| Bionox NPP | Imunofan | Russia | Candles | The recommended daily intake for adults and children is 100 micrograms ( 1 candle). Treatment is prescribed in courses from 8 to 20 days, with long breaks. |
| Bionox NPP | Imunofan | Russia | Spray | The spray is used 1 to 2 times a day. At the same time, one dose of the drug is sprayed into each nasal opening at a time ( one press - 50 mcg). Usually, treatment is prescribed in courses from one week to a month. The maximum daily dose for adults and children should not exceed 150-200 micrograms. |
The mechanism of the therapeutic action of the drug
Imunofan is a complex protein that consists of 6 amino acids ( its other name is arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine).Imunofan belongs to drugs that can increase the stability of genetic material ( DNA) immune cells organism. This is necessary for the cells of the immune system to fully fulfill their role, since the indicators of the state of the immune system are directly related to the processes of DNA damage and repair. The appearance of such processes occurs due to the influence of unfavorable factors on immune cells ( intoxications, infections, tumors, etc.).
Also given medicine has antioxidant, detoxification and immunoregulatory effects. Getting into the body different ways, Imunofan works over a long period of time.
Conventionally, this period is usually divided into several phases:
- phase quick action;
- intermediate phase;
- long-acting phase.
Intermediate phase has a duration of about one week. During this period of time in the body, the amount of active oxygen stabilizes to physiological parameters. Such oxygen in large quantities ( especially with serious illnesses ) is released during phagocytosis reactions ( the process of processing foreign particles by immune cells), which can have an adverse effect on the surrounding tissues. Thus, imunofan, by normalizing the amount of active oxygen, reduces the risk of damage to its own tissues by the cells of its own immune system.
Long-acting phase lasts for 4 months from the end of the intermediate phase. Imunofan stimulates the production of cytokines ( substances that stimulate and regulate the immune response) and increases the sensitivity of immune cells to them. It restores the processes of cell division and increases the number of lymphocytes and antibodies ( a type of protein capable of neutralizing foreign particles) in blood.
The hepatoprotective effect of Imunofan is realized by preventing the disintegration of cell membranes of hepatocytes ( liver cells), as well as by stabilizing their DNA. Ultimately, this leads to a decrease in the level of bilirubin and transaminases in the blood ( indicators that increase with liver damage).
Due to the high absorption rate and the effectiveness of its action, Imunofan is prescribed in very low doses. This medicinal substance entering the body, participates in natural processes metabolism and therefore does not have a toxic effect on the body.
For what pathologies is it prescribed?
Since imunofan does not have direct therapeutic effect, it can be used for any diseases that are accompanied by the development of immunodeficiency ( decreased immunity). Below is a table containing a list of pathological processes, in which this drug is especially often prescribed.Imunofan use
How to use the medication?
Usually, doctors prescribe this drug in the form of an injection solution or in the form of rectal suppositories ( candles). The daily injection dose should be 50 micrograms ( 1 injection), while for suppositories the daily dose is 100 micrograms ( 1 candle). The doctor can prescribe injections both subcutaneous and intramuscular ( depends on the type of disease). Age does not affect dosage calculation of this drug so the doses for adults and children are the same. It is also possible to use Imunofan in the form of a spray for intranasal use. Most often sprayed once ( 50 mcg) in each nasal opening from 1 to 2 times a day. The maximum daily dose should not exceed 200 micrograms. When using the spray, there may be some difficulties with the method of its use.
Hives characterized by skin rashes red, rising above the surface of the skin. These rashes are somewhat similar to blisters from a nettle burn. Most often, urticaria appears on symmetrical areas of the skin, having either a local or diffuse nature of the lesion.
Erythema Is an allergic reaction characterized by reddening of an area of the skin or mucous membrane. Erythema is not accompanied painful sensations and itching. This allergic manifestation can occur on almost any part of the body. Rashes are both single and multiple ( some of them can be interconnected).
Quincke's edema is an inflammation of the subcutaneous fat layer of the skin. Clinically, such inflammation is manifested by the occurrence of edema of the face, neck, extremities, genitals and other places of congestion. subcutaneous tissue... The most dangerous complication this reaction is laryngeal edema and the possibility of asphyxia ( blockage of the lumen respiratory tract leading to respiratory failure ). The characteristic difference between Quincke's edema from others allergic rashes the absence of itching and redness of the affected area of the skin serves.
Anaphylactic shock characterized by sharp decline blood pressure and rapidly developing narrowing of the lumen airways... This type of allergy is also characterized by the appearance of pronounced local symptoms ( skin redness, swelling, itching, blistering, ulceration) at the injection site of the drug allergen. Anaphylactic shock is dangerous allergic reaction, in the event of which it is necessary to provide emergency medical care.
The approximate cost of the medication
Imunofan is produced only in Moscow ( by Bionox) and therefore can be easily purchased in this city. The drug can also be marketed in other cities of the Russian Federation. However, most often it can be ordered through pharmacy websites or by mail. Below is the average cost of this drug for different regions, excluding shipping costs ( for Moscow full price ).| Town | average cost drug | ||
| Injection | Rectal suppositories (candles) | Spray | |
| Moscow | 521 ruble | 550 rubles | 849 rubles |
| Kazan | 407 rubles | 400 rubles | 740 rubles |
| Krasnoyarsk | 406 rubles | 402 rubles | 749 rubles |
| Samara | 405 rubles | 400 rubles | 749 rubles |
| Tyumen | 407 rubles | 405 rubles | 744 rubles |
| Chelyabinsk | 406 rubles | 400 rubles | 749 rubles |
Imunofan's instruction
Imunofan is a synthetic immunomodulator. It has antitoxic and hepatoprotective properties, improves immunity. Three phases are determined by the time of exposure to the drug. The fast phase takes effect two to three hours after taking the medicine, lasting three days. The middle phase begins to act two to three days after the application of Imunofan, its duration is limited to ten days. The slow phase takes effect a week after the drug is used, and its duration is four months.
The fast phase is characterized by the presence of hepatoprotective and detoxifying action of the drug. Blood cholesterol levels are lowered, and the drug prevents liver cells from decaying. The middle phase is mainly providing antibacterial action... When the slow phase takes place, the immune parameters return to normal, the necessary antibodies begin to be produced more actively. The drug has the property due to which tumor cells become more sensitive if they are exposed to chemotherapy.
The drug is used both as prophylactic, and in the form of complex therapy for diseases such as viral, bacterial diseases in acute and chronic form, with chlamydia, toxoplasmosis, herpes, HIV, papillomatosis, diphtheria, hepatitis of various origins... Imunofan is indicated in the presence of burns, poorly healing wounds. Also, the drug is recommended for the treatment of sepsis and related complications, with diseases of the gallbladder, psoriasis. Medication is prescribed if diagnosed rheumatoid arthritis, inflammation of the pancreas, broncho-obstructive syndrome. If vaccination is done while taking Imunofan, then the drug increases its effect.
The drug Imunofan is a solution for injection, there is also rectal suppositories and a nasal spray. There is an instruction, which provides information on the recommended doses for use, the duration of the course. It must be borne in mind that in some cases there is an allergy to Imunofan. The drug should not be given to children under the age of two, pregnant women, especially those who have rhesus conflict.
The peculiarity of the treatment is such that during the treatment of chronic inflammation, a temporary transition of the disease to acute form... The effect is due to the therapeutic properties of this medicinal product... Even if you are taking Imunofan for prophylaxis, you need to consult a doctor.
Reviews about Imunofan
Both specialists and patients leave about Imunofan most often positive reviews... The effectiveness of this drug has been confirmed by numerous scientific articles written on the basis of the research. There are many reviews in which patients say that this drug was prescribed to them in connection with problems of the genitourinary sphere. In each case, it is stated that there was a noticeable improvement in the condition, there were no negative side effects. But it should be noted that Imunofan was used as part of complex therapy, as well as in the form of a supportive agent.
There are people who start the prophylactic use of the drug on their own as soon as they notice the first signs of flu. In such cases, it is always said about a noticeable improvement in well-being, the disease either completely recedes, or proceeds much easier.
There is also one negative feedback, he was left by the parents of a four-year-old baby, diagnosed with pneumonia and chlamydia. When the injection was made, the child began to have a headache, rose temperature... Obviously, this was one of the rare cases when the drug is not tolerated by the body, and there are warnings about this in the instructions. As always, in conclusion, we remind you of the need to consult with a specialist on the use of Imunofan for treatment and prevention.
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Imunofan is a drug belonging to the group of immunostimulating agents, used to treat or prevent immunodeficiency states, as well as to stimulate the body's defenses during the cold season.
What are the composition and form of release of Imunofan?
The active ingredient Imunofan is represented by arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine, which is a synthetic derivative of thymopoietin. The amount of active ingredient is 50 micrograms in 1 dose of nasal spray or 100 micrograms in one suppository, as well as 5 milligrams in a millimeter of solution.
The drug Imunofan is available in the form of a nasal spray in vials of 8.5 milliliters, in addition, in rectal suppositories, as well as in the form of a 0.005% solution in ampoules of 1 ml. Regardless dosage form, the pharmaceutical agent is dispensed with a prescription.
What is Imunofan's action?
The drug Imunofan is capable of exerting the following pharmacological effects: immunostimulating, detoxifying, in addition, hepatoprotective and antioxidant. The use of a medication can help eliminate multidrug resistance of tumor cells.
The effect of the drug has a pronounced staging, is divided into 3 phases: fast (occurs within 2 - 3 hours after application), medium (from 3 hours to 3 days) and slow (from 3 days to 4 months).
At the beginning of the treatment period, the drug is capable of exerting a predominantly detoxifying effect, which is based on the stimulation of reactions for the synthesis of ceruloplasmin, lactoferrin and some other chemical compounds.
During this period, in addition to the above detoxification effect, the drug is able to normalize the lipid composition of the blood, suppress the synthesis of arachidonic acids and improve the phospholipid composition of cell membranes.
The middle phase is characterized by the stimulation of the cellular link of the immune system. In particular, an increase in the activity of phagocytic reactions is carried out, which leads to the rapid death of many bacteria and viruses located inside the cells.
V slow phase the stimulation of cellular reactions of immunity continues, but in addition to this, the humoral link is also involved, which is responsible for the synthesis of specific antibodies and the production of immunoglobulins and interferons, which prevent the penetration of pathogens into healthy cells.
Immunofan, as mentioned above, increases the susceptibility of tumor cells to cytostatic treatment. This circumstance contributes to a decrease in the dosage of highly toxic medicines, which reduces the likelihood of developing severe side effects.
What are the indications for use of Imunofan?
The appointment of the pharmaceutical agent Imunofan is carried out in the presence of the following diseases:
Treatment and prevention of chronic inflammatory diseases;
Treatment of toxic conditions involving liver damage;
As an element complex treatment opportunistic infections (caused by opportunistic microorganisms);
As part of a comprehensive therapy tumor diseases;
Burn disease;
Endocarditis;
Complications of purulent diseases;
Broncho-obstructive syndrome;
rheumatoid arthritis;
Psoriasis;
Cholecystopancreatitis.
I remind you that the use of a drug is possible only when it has been prescribed by a specialist. And we are on this page of the site www.! Any use of Imunofan without a doctor's approval may result in negative consequences.
What are the contraindications for use of Imunofan?
The use of the medication is contraindicated in the presence of any of the following conditions: pregnancy; age less than 2 years; in addition, individual intolerance.
What are the use and dosage of Imunofan?
The dosage of the drug depends on the dosage form, age and indications for use. The spray should be used intranasally. In this case, the bottom of the can should be turned up. One shot contains 50 micrograms active substance... The maximum daily dose is 200 mcg. The duration of treatment is determined by a specialist.
Rectal suppositories should be injected deep into the rectum. Optimal time for this procedure - before bedtime. The recommended dosage is 100 micrograms, which equals one candle. The course of treatment is from 8 to 10 days.
The solution is applied before radical or radiation treatment... Before starting cytostatic therapy, 1 milliliter of the drug is prescribed every other day. It is recommended to carry out 3 - 5 procedures. For widespread lesions, for example, in the presence of metastasis, you need to apply 1 milliliter every day for a week. After 20 days, the course of therapy is repeated.
What are the side effects of Imunofan?
In most cases, the use of a pharmaceutical agent, regardless of the dosage form, is not accompanied side effects... And this is, of course, good! In rare situations, only minor allergic manifestations as itchy skin, focal redness, peeling and swelling.
How to replace Imunofan, what analogs?
The drug Imunofan can be replaced by the drug arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine.
Conclusion
We have reviewed the drug Imunofan, instructions for the use of the drug. To implement a pronounced immunostimulating effect, one should adhere to a complex treatment, including proper nutrition, vitamin therapy, prevention of re-infection.
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