120 mg per day or 2 tablets of 240 mg after meals with plenty of liquid. When especially severe cases Prescribe 6 tablets per day. The intake should be divided into two parts - morning and evening. Therapy usually lasts no more than 5 days. For long-term treatment, take 2 tablets of 120 mg per day.

For children, the drug is prescribed in the form of a suspension, twice a day. Each bottle of suspension has a measuring cap with divisions of 2.5, 5 and 7.5 ml. For those aged less than a year, 2.5 ml of medication is prescribed every 12 hours. If the child is between 1 and 3 years old, 5 ml is usually prescribed twice a day. From 4 years of age you can take 10 ml of the drug, depending on the intensity of the disease and the pediatrician’s recommendations.

Biseptol has a number side effects which may occur in case of overdose or improper use: spasms of the respiratory muscles, digestive disorders, diarrhea, jaundice, inflammation of the mucous membranes of the mouth. It is also possible that kidney function may deteriorate and allergic reactions. Before taking the drug, you should consult with your doctor and take a necessary tests. The medication is taken under the supervision of a specialist.

note

You should not use Biseptol if you are intolerant to sulfonamides, which are included in the tablets. It is also recommended to carefully treat with the medicine if there are problems in the functioning of the kidneys and liver. For patients with kidney disease, a dose is prescribed depending on the current creatinine levels.

Instructions

"Biseptol" is used to treat acute and chronic bronchitis, pleural empyema, lung abscesses, bronchiectasis, pneumonia. It is also prescribed for urethritis, pyelitis, chronic pyelonephritis, prostatitis, gonococcal urethritis, infectious diseases Gastrointestinal tract, surgical and other infections, uncomplicated gonorrhea, septicemia. The drug is effective against pneumococci, staphylococci, Bacillus typhoid fever, dysentery, E. coli, streptococci, Proteus. "Biseptol" has no effect on mycobacterium tuberculosis, Pseudomonas aeruginosa, or spirochetes.

"Biseptol" is taken after meals with the required amount of water. Adults and children over 12 years of age are prescribed 960 mg of the drug 2 times a day, for long-term treatment - 480 mg 2 times a day. In cases of severe infectious disease or him chronic form single dose increase by 30-50%. Children aged 3 to 5 years are given 2 tablets. (120 mg) 2 times a day, aged 6 to 12 years - 4 tablets. (120 mg) or 1 tablet. (480 mg) 2 times a day. The duration of taking the drug is 5-14 days.

"Biseptol" can cause the following side effects: anorexia, vomiting, nausea, pseudomembranous colitis, diarrhea, abdominal pain, allergic manifestations on the skin (rash, urticaria). Possible development of epidermal toxic necrolysis, acute liver necrosis, aplastic anemia, hemolytic anemia, eosinophilia, allergic myocarditis, anaphylactic reaction, vascular edema, serum sickness, fever, chills, hepatitis, pancreatitis.

"Biseptol" is contraindicated in case of hypersensitivity to its components, during pregnancy and lactation, in case of damage to liver tissue, severe renal failure, severe hematological diseases. The drug is prescribed with caution for folic acid deficiency, bronchial asthma, diseases thyroid gland.

In case of long-term treatment (more than 1 month), blood tests should be performed regularly to monitor hematological changes. Particular care must be taken when treating elderly patients with Biseptol. To prevent crystalluria, it is recommended to increase the amount of fluid consumed. During treatment with Biseptol it is not recommended to use cauliflower, legumes, spinach, tomatoes, carrots, excessive sun exposure must be avoided.

"Biseptol" - antimicrobial agent wide range actions. This drug ensures oppression pathogenic microorganisms, causing disease, has a bactericidal effect. You can take Biseptol in the form of tablets, suspensions and infusion solution.

Instructions

The drug "Biseptol" is prescribed for a number of infectious and inflammatory diseases. This medicine is used to treat infections respiratory tract, in particular, “Biseptol” is indicated for the treatment of bronchitis, pneumonia, as well as pleural empyema and lung abscesses. The drug is used in the treatment of infectious diseases genitourinary system: urethritis, prostatitis, pyelonephritis, salpingitis, gonorrhea. Biseptol is also used in the treatment of dysentery, diarrhea, cholera, typhoid fever and paratyphoid fever. The drug is effective for infectious lesions of the skin and tissues, including those prescribed for furunculosis and purulent formations. Biseptol is also used to treat sinusitis, otitis and meningitis.

Biseptol tablets should be taken after meals, 2 times a day. Children 2-5 years old are prescribed 240 mg, 5-12 years old - 480 mg per dose. Children from 12 years of age and adults use a dosage of 960 mg. For long-term treatment, the amount of the drug must be reduced to 480 mg, also taking the drug twice a day. The duration of therapy depends on the complexity of the disease and is 5-14 days. During therapy chronic infections And severe course illness one-time can be increased by 30-50%. When treating pneumonia, the medicine is taken at the rate of 100 mg of sulfamethoxazole per kg of patient weight per day. The drug should be taken for 2 weeks, the interval between dosages should be 6 hours. For gonorrhea, 2 g of sulfamethoxazole is indicated 2 times a day at intervals of 12 hours.

Biseptol suspension is indicated for adults and children from 3 months. The drug is taken every 12 hours. Babies 3-6 months are given 2.5 ml, 7 months - 3 years - 2.5-5 ml of the product. Children 4-6 years old are prescribed 5-10 ml, 7-12 years old - 10 ml of suspension. Adults and adolescents should take the medicine 20 ml at a time. Treatment should be carried out for 1.5-2 weeks, for dysentery - 5 days. Shake the bottle of suspension well before use.

Biseptol solution is administered intravenously. For children over 12 years of age, a single dosage is 10 ml of the product. Before administration, the medicine should be diluted in 250 ml of dextrose or sodium chloride solution. Biseptol is administered intravenously every 12 hours for 5 days. For particularly severe symptoms, the dosage can be increased to 3 ampoules with a frequency of administration 2-3 times a day. Children's daily dose sulfamethoxazole is 30 mg/kg body weight. This amount of medicine should be used 2 times. The infusion should not last longer than 1.5 hours.

Tip 4: Biseptol: instructions for use, price, analogues

The modern pharmaceutical industry offers doctors and patients a huge selection of medications to treat various diseases. Among antibacterial drugs There are “long-livers” that have been successfully used for treatment for many years. One of these drugs is Biseptol.

Biseptol: active ingredient, release forms and reviews

Active ingredient: Co-trimoxazole. This substance consists of two components, essentially two active ingredients: sulfamethoxazole and trimethoprim. Co-trimoxazole is synonymous with this pair of substances. Release forms: tablets 120 and 480 milligrams and suspension 240 milligrams. The 120-milligram dosage and suspension are considered pediatric formulations, while the 480-milligram dosage is more commonly used in adults. There is also a release form for this drug in ampoules. Liquid "Biseptol" is available in ampoules of 5 milliliters and 480 milligrams. Reviews about the drug were divided 50/50.

The product is available in the form of tablets, syrup (suspension). For adult patients, the content of 480 mg of active elements is provided. Biseptol tablets are also produced in a dosage of 120 mg, which helps children. The active substances are sulfamethoxazole and trimethoprim. To improve the absorption of the drug, the drug contains additional components: propylene glycol, propyl parahydroxybenzoate, methyl parahydroxybenzoate, starch and other elements. The box contains instructions for use with a description of the drug.

Pharmacology

The action of the active substances ensures the bacteriostatic and bactericidal properties of the drug, aimed at destroying and stopping the proliferation of pathogenic microorganisms. With the help of the drug they fight staphylococci, coli, streptococci, bacteria that cause dysentery and typhoid fever, pneumococci. Resistance to active substances have Pseudomonas aeruginosa, spirochetes, microbes that provoke the development of tuberculosis. In such cases, taking the medicine is useless.

The drug "Biseptol", from which the effect occurs after 3 hours, is absorbed quite quickly after oral administration. The action lasts for 7 hours. Then the medication is eliminated from the body within 24 hours.

Medicine "Biseptol": what helps

Tablets and suspension are prescribed for infections:

Respiratory organs.
Urinary tract.
Gastrointestinal system.
ENT - organs.
Skin and soft tissues.

The medication helps with such pathologies as:

pyelitis, paratyphoid fever, cholangitis;
lobar pneumonia, tonsillitis, furunculosis;
urethritis, cholera, sinusitis;
acne, prostatitis, typhoid fever;
bronchiectasis, otitis media, pyelonephritis;
cholangitis, scarlet fever, pyoderma;
dysentery, bronchitis, laryngitis;
gonorrhea, gastroenteritis, salmonella carriage;
bronchopneumonia, epididymitis;
lymphogranuloma (venereal).

Together with other medications, Biseptol is used for the treatment of acute brucellosis, toxoplasmosis, South American blastomycosis, and malaria.

Biseptol tablets: instructions for use

The medicine must be taken orally after meals. During therapy the patient needs drinking plenty of fluids, he should drink at least 2 liters of water per day. For gastrointestinal infections, genitourinary organs, exacerbations of chronic bronchitis, adults are prescribed 1 tablet of Bispetol 480 or 2 - 120 mg. You need to take the medicine 2 times a day. The course of treatment is 2 weeks, for diseases digestive system- up to 5 days.

Biseptol is given to children depending on body weight. For inflammation of the urinary ducts, damage to the digestive organs by Shigella, and acute otitis media, 48 mg of medication per kg of weight is prescribed. Must be taken every half day. The suspension is usually given to children under 12 years of age twice a day. The dosage varies from 2.5 for babies 3-6 months to 10 ml for 12 year olds. Adults can also use a suspension in a volume of 20 ml 2 times a day.

Contraindications

"Biseptol" instructions for use prohibit taking when:

individual sensitivity to the composition;
anemia;
leukopenia;
children with jaundice;
renal or liver failure;
agranulocytosis;
pregnancy and lactation;
children under 3 months.

Side effects

Biseptol is not a harmless drug. In some cases, after its use, patients experience negative reactions from the body. Side effects of the drug include:

dizziness, bronchospasm, dyspeptic disorders;
megaloblastic anemia, crystalluria, myalgia;
headaches, vomiting, pulmonary infiltrates;
cholestasis, agranulocytosis, interstitial nephritis;
arthralgia, diarrhea, neutropenia;
polyuria, thrombophlebitis, loss of appetite;
leukopenia, toxic nephropathy, hypoglycemia;
epigastric pain, allergies, thrombocytopenia;
gastritis, hepatitis, glossitis.

Analogues and price

The drugs Triseptol, Oriprim, Baktiseptol, Sumetrolim, Groseptol, Bactrim, Co-Trimoxazole have a similar effect. You can buy Biseptol, the price of which is 35-130 rubles, at the pharmacy.

Conditions of release and storage

Biseptol tablets are available in pharmacies with a doctor's prescription. You cannot use the drug yourself or on the recommendations of third parties who are not specialists.

The shelf life of Biseptol tablets from the date of their manufacture is 5 years. The drug must be stored in a dry, inaccessible place with an air temperature no higher than +25° C.

Biseptol is a fairly well-known drug in Russia. It refers to antiseptics, i.e. substances that suppress the production of certain pathogenic bacteria. Many people who have been prescribed this drug are interested in whether Biseptol is an antibiotic, because It is widely believed that antibiotics are harmful to the body.

Description and use of the drug

Is Biseptol an antibiotic or not? No. Biseptol belongs to a fundamentally different group medicines– antibacterial compounds based on sulfonamides.

They differ from antibiotics, firstly, in their origin: sulfonamides are exclusively artificial agents, synthesized in a chemical factory and are not found in nature, while all antibiotics, without exception, have a natural or as a last resort semi-synthetic base.

Secondly, sulfonamides have a fundamentally different mechanism of action: they are integrated into the structure of pathogenic microorganisms or protozoa and replace para-aminobenzoic acid in their protein, which makes it impossible for bacteria, protozoa and even some types of fungus to reproduce.

Although the fungus is in most cases resistant to these substances, this is especially true for the pathogenic fungus of the genus Candida. Moreover, sulfonamides, as well as antibiotics, can create (under certain conditions) a favorable environment for the occurrence of candidiasis.

The action of biseptol is provided by 2 active synthetic compounds: sulfamethoxazole, which has an inhibitory effect on bacteria and protozoan single-celled organisms, and trimethoprim, a synergistic substance that enhances healing effect main ingredient.

Biseptol is absorbed into the blood within 1-2 hours, dissolving in the stomach. Maximum concentration This drug reaches the blood 6-7 hours after the patient takes the drug. The main route of elimination is the urinary tract.

Many pathogens are sensitive to the main component, sulfamethoxazole, including:

Therefore, the use of Biseptol is advisable if a person has inflammation of the ENT, gastrointestinal tract, genitourinary system and others caused by a bacterial infection.

Note: for diseases caused by viruses or fungal infections, for example colds or candidiasis, the use of Biseptol is pointless and useless, because it has no effect on viral and mycological life forms. If, for example, you have a cough, then Biseptol can only help if the cause of the disease is bacteria. Also, this drug is ineffective against spirochetes and the causative agent of tuberculosis.

What does the drug Biseptol help with? Many people try to take Biseptol for a cold cough, but, as mentioned above, in most cases this is not justified. However, it is recommended to take Biseptol if:

In addition, the list of indications for the use of Biseptol includes bacteriological infections stomach, intestines, etc., such as:

diarrhea;
typhoid and paratyphoid fever;
dysentery;
cholera;
poisoning.

It can be successfully used for skin diseases such as furunculosis and pyoderma, as well as for inflammation of the brain - meningitis, wound infections, incl. after surgical intervention, etc.

Biseptol is prescribed for the prevention of diseases such as Pneumocystis pneumonia in patients suffering from HIV/AIDS.

Release form and treatment regimen

Most often, the drug is available in the form of tablets of 120, 480 and 960 mg. Sometimes a suspension syrup or dry concentrate is used to prepare an infusion solution. The main substances in them are contained in a ratio of 5 to 1, i.e. for 5 mg of sulfamethoxazole there is 1 mg of trimethoprim. Tablets of 960 mg are a form with an increased concentration - “forte” for use in emergency cases.

The main method of using Biseptol is oral, i.e. suspension or tablets. In cases of severe infection, it can be given intramuscularly or intravenously through a drip.

There is Biseptol for children and adults. The release form for young patients is a suspension, syrup with strawberry flavor. For infants from 3 to 6 months, the drug can be given in the form of a suspension of 2-2.5 ml 2 times a day (time period 12 hours). For older babies, from 7 months to 3 years – 5 ml twice a day. A child over 3 years old can be given tablets if he is able to swallow them.

In this case, the dose is:

240 mg 2 times a day for ages 3-5 years;
480 mg 2 times a day for ages 6-12 years;
over 12 years old – 960 mg 2 times a day.

For adults, Biseptol is usually prescribed in a dosage of at least 960 mg twice a day, but if this medicine is prescribed for a long course to treat a disease that has become chronic, then the dosage in an adult can be reduced to 480 mg.

How to use? The usual course of treatment lasts 2 weeks. There is no need to shorten it, because... because of this, an untreated disease can become chronic, while pathogenic bacteria will acquire resistance to sulfonamide, and the disease will no longer respond to treatment with these drugs.

You should take the tablets after meals with plenty of water. At the same time, you should not eat foods rich in protein, including beans (beans, soybeans, peas, lentils), cheese, meat and dairy products, because. protein reduces effective action drug. Drinking alcohol is prohibited.

There is also an injection method of using biseptol, it is used for severe forms diseases, and also, if necessary, to achieve increased concentration drug in spinal cord. Injections can be given to children from the age of 6 years. The dosage is the same in terms of the content of the main components in the solution.

Note: with a long course of treatment, it is necessary to monitor blood composition. Concomitant use of folic acid may be required.

Possible adverse reactions and contraindications

The main feature of any sulfonamides is that many pathogens quickly acquire resistance to it, i.e. become insensitive. It can be prescribed only after the doctor, after conducting an analysis, makes sure that the pathogens are sensitive to this drug.

In addition, Biseptol has quite a lot of side effects: in particular, it causes gradual intoxication of the liver and kidneys, and can inhibit hematopoiesis (with long-term therapy large doses), and allergies to biseptol are not uncommon.

Biseptol during pregnancy is under absolute ban, treating newborns with it is also prohibited.

How else could he be dangerous? The danger is a large overdose, and the side effects are as follows:

aplastic anemia, which can lead to bone marrow atrophy;
liver and kidney dysfunction;
crystallization of urine, appearance of “sand”;
dermatological problems;
candidiasis;
myalgia and arthralgia – when muscles and joints hurt
gastritis and pancreatitis, nausea and vomiting;
anemia, decrease in leukocytes and platelets in the blood;
spasms in the respiratory system.

It may, although in rare cases, cause chills or fever. Also, when treated with Biseptol, side effects can manifest themselves in the form of depression, apathy, tremor (tremors in the fingers), etc.

This drug is absolutely contraindicated in the following groups of patients:

Interaction with other drugs

Biseptol can interact with many of the medications that a person can take for other concomitant diseases.

There are certain drugs with which it should not be taken, for example:

Acetylsalicylic acid.
Nalgesin and its analogues.
Phenylbutazone.
Barbiturates
Diuretics, especially thiazide-based ones.

Biseptol can chemically enhance the effect of:

Anticoagulants.
Glipizide, gliquidone and other antidiabetic drugs (and often cause allergies when taken together with them).
Methotrexate.
Phenytoin.

It is very important to know that Biseptol weakens the effect hormonal contraceptives. If you use during treatment oral contraception, then you should notify your doctor about this and, on his recommendation, increase the dose.

If you combine Biseptol with Pyrimethamine, the chances of developing anemia increase. The effect of Biseptol is reduced by Rifampicin and painkillers of the novocaine group.

Analogues of the drug

This substance has many synonyms - these are medicines that have the same active chemical compound in their composition, and therefore have similar pharmacological properties. Synonyms of biseptol are:

Abatsin.
Andoprine.
Abactrin.
Bactrim.
Bactramin.
Bactifer.
Oriprim.
Oribact.
Cotrimol.
Cotrimaxazole.
Kotribene.
Sulotrim.
Sulfatrim.
Trimosul.
Ectaprim.

An analogue is a medicine that has similar pharmacodynamics and pharmacokinetics, but different active ingredients in the composition. In some cases, even a drug from a different group of drugs, but prescribed to cure the same diseases, may be called an analogue.

In a narrow sense (according to similar pharmacology), Biseptol analogues include other drugs from the sulfonamide group, to which it itself belongs. This is the well-known Streptocide, Sodium Sulfathiazole, Mesalazine and other sulfonamides, produced under various brand names, in different dosage etc. In a broad sense, an analogue of Biseptol can even be understood as antibiotics.

In pharmacology it is considered combination drug, capable of influencing a wide range of types of unfavorable microorganisms.

If the microbial infection is moderate, therapy can be used instead of antibiotic treatment sulfa drugs. One of popular means This group is Biseptol in tablet form.

Biseptol - what kind of medicine?

Biseptol is a sulfonamide group agent with a complex composition. The 480 mg tablets contain 80 mg of trimethoprim (an antibiotic that works only through the bacteriostatic mechanism of action of sulfonamide) and 400 mg of sulfamethoxazole (sulfonamide). The drug is also available in dosages of 120 and 240 mg.

This pharmacological combination has another name - co-trimoxazole.

The tablets also include additional substances - magnesium stearate, starch, talc, propylene glycol. The drug is very inexpensive - 100 rubles/28 tablets. There are others on sale dosage forms. This is a suspension (syrup) for children from 3 months, a solution for infusion (used from birth, in a premature baby - from 2 months).

This medicine belongs to the combination antibacterial agents, it can be taken for a whole range of microbial pathologies. Sulfamethoxazole disrupts the formation of essential acids for bacteria, which are part of bacterial cells. Trimethoprim is an “enhancer” of the action of sulfamethoxazole, preventing acid molecules from being reduced. Eventually protein metabolism in microbial cells is disrupted, their division stops. In tablet form, Biseptol helps against diseases caused by:

The medicine also works well against protozoa - plasmodium, toxoplasma, and against a number of pathogenic fungi. Treponema, Corynebacter, Leptospira and all viruses do not respond to therapy with this medicine, as do Mycobacterium tuberculosis.

Indications of the drug

The drug helps against most microbial diseases caused by bacteria sensitive to it. For adults and children, the medicine is most often prescribed for ENT diseases and respiratory tract diseases. Biseptol is recommended for cough, sore throat, otitis media, and sinusitis. It is also prescribed for pneumonia, tracheitis and bronchitis, in complex therapy- with lung abscess, empyema. The medicine is indicated for chronic bronchitis and even for severe Pneumocystis pneumonia in people with weakened immune systems.

Biseptol is also prescribed for scarlet fever in children.

Infections of the urinary system and genital area are also successfully treated with this tool. These include:

If diseases of the peritoneal organs are also caused by microbes, Biseptol is prescribed for their acute and chronic course to relieve inflammation. Among them are typhus, paratyphoid, cholera, unknown origin diarrhea. With the help of Biseptol, dysentery, salmonellosis (in the form of carriage), gastroenteritis and cholecystitis are treated. Medicine is also prescribed for damage to soft tissues and skin due to pyoderma, boils, purulent rashes, wounds, abscesses. The tablets are taken after operations, in complex therapy for malaria and whooping cough.

Contraindications and side effects

The drug is contraindicated during pregnancy, especially during early stages, during lactation. It is not prescribed in tablet form to children under 3 years of age. Other contraindications:

Patients with a lack of vitamin B9 in the body while taking it are at high risk of developing serious anemia. Therapy is carried out with caution in case of pathologies of the thyroid gland and asthma.

The drug inhibits the growth of E. coli in the intestines, which disrupts the production of B vitamins.

More often, Biseptol is well tolerated, but side effects are still possible. Headaches, neuritis, dizziness may develop, and sometimes depression and tremors are noted. Some patients develop respiratory disorders and bronchospasm. There is also a risk of developing:

In the most severe and rare cases, hepatitis, pulmonary infiltrates, pancreatitis, anemia and blood disorders, nephritis are possible.

Exact instructions

Drink Biseptol after meals (to avoid damage to the gastrointestinal tract), drinking plenty of water. The dose is set strictly individually, especially for children over 3 years of age. At 3-5 years old, 240 mg twice a day is recommended; from 6 to 12 years old, 480 mg twice a day is recommended. The doctor decides how much and in what frequency to take the medicine, depending on the type of disease:

Course for bronchial infection, respiratory system may be 2 weeks, as with other serious illnesses. In milder cases, the course lasts 5-10 days. If required, under the supervision of a doctor, the dose is increased by 30-50%, but only for the first 5-7 days. If the course is more than 5 days, it is necessary to take blood tests to prevent consequences (anemia and others). If there are any changes, therapy is introduced folic acid 5-10 mg/day.

Analogues, what else should you know?

There are a number of analogues from the sulfonamide group, but replacing the drugs yourself is strictly prohibited - they can have different effects.

Biseptol is a combination drug that belongs to the group of sulfonamides. This medicine has a broad spectrum of action and helps cope with microbes, but is not. Moreover, the substance has many side effects and contraindications, so only a doctor can prescribe it.

Composition, release form, packaging

The tablets for adults contain 0.4 mg of sulfamethoxazole and 0.08 g of trimethoprim. Tablets for children have a lower dosage - 0.1 g of sulfamethoxazole and 0.02 g of trimethoprim. The drug is released in tablet form. There are 20 pieces in the package.

Biseptol release forms

Manufacturer

The medicine is produced by the Polish Pabianicki Pharmacological Plant.

Indications

The drug is used for therapy infectious pathologies, which are the result of infection by various microorganisms. Indications include the following anomalies:

infectious lesions of the respiratory system - pulmonary, sinusitis, bronchitis, pneumonia;
sinusitis;
or ;
inflammation and abscess of the brain;
infectious lesions of the genitourinary system - urethritis, cystitis, prostatitis, salpingitis;
infection of the digestive system - cholera, paratyphoid, shigellosis;
gonorrhea;
infectious skin lesions - pyoderma, .

Contraindications

Biseptol should not be used in the following cases:

complex shapes;
pregnancy;
lactation;
diseases of the hematopoietic system;
lack of glucose-6-phosphate dehydrogenase – is hereditary;
age up to 3 months;
premature babies;
serious;
increased bilirubin levels in children;
high sensitivity to the ingredients or other sulfonamides.

Use the product with great caution when combined with other medications. This is also true for people with asthma or folic acid deficiency. Caution is recommended in case of thyroid pathologies. Doctors give similar recommendations to children and the elderly.

Mechanism of action

Combination active ingredients allows you to obtain a bacteriostatic effect and destroy bacterial microorganisms. The product is effective against various bacteria.

The effect of the drug is due to its blocking effect on the metabolic processes of bacteria. Sulfamethoxazole disrupts the synthesis of dihydrofolic acid, and trimethoprim interferes with the next stage of metabolism.

With the help of this remedy it is possible to cope with streptococci, pneumococci, staphylococci. It is effective against infection with typhoid and dysentery bacilli, as well as infection with E. coli. At the same time, the drug does not allow you to cope with Pseudomonas aeruginosa, the causative agent of tuberculosis, and spirochetes.

Instructions for use

The dosage of the drug is selected individually. The product can be taken after meals with the required amount of liquid. The volume of the substance is selected according to age. So, at 3-5 years old, 240 mg is indicated. Children 6-12 years old need to take 480 mg. This should be done twice a day.

In case of pneumonia, it is necessary to calculate daily dosage thus: 100 mg of sulfamethoxazole per kilogram of patient weight. A period of 6 hours should be maintained between doses. Duration of use is 2 weeks.

If gonorrhea develops, the dosage should be 2 g of sulfamethoxazole twice a day. There should be a 12 hour gap between uses.

All patients over 12 years of age need to take 960 mg of the drug twice a day. If planned long-term treatment, the dosage is reduced to 480 mg.

The duration of use of this product is 5-14 days. If the disease is complex or present, the single dose may be increased by 30-50%.

When the duration of therapy is more than 5 days or increasing the dosage of the drug, it is important to keep peripheral blood counts under control. If abnormal changes are observed, folic acid is prescribed. The dosage of the vitamin is 5-10 mg per day.

In people with kidney failure, in which creatinine clearance is 15-30 ml per minute, the usual volume is halved.

How to take Biseptol for certain diseases:

Side effects

Biseptol usually has excellent tolerability. However, sometimes it provokes undesirable consequences:

The digestive organs react to the use of the drug with the appearance of diarrhea and loss of appetite. Some people experience. In rare cases, glossitis, stomatitis, etc. develop.
Nervous system may react to taking the drug, depressive states, . Some people experience.
On the part of the kidneys, the volume of urine increases or the organ becomes inflamed. Sometimes .
If the respiratory system is affected, there is a risk of suffocation, lack of air, and coughing.
When the hematopoietic system is damaged, the volume of leukocytes and neutrophils decreases. There is also a risk of a decrease in platelet count or the development of anemia, accompanied by a lack of folic acid.
Sensations may occur. In rare cases, syndromes develop or. A dangerous complication can also become .
High sensitivity to ultraviolet light may develop.
There are isolated examples of chills after using the product.

Biseptol can also cause discomfort in muscles and joints. There is a risk of thrombophlebitis in the injection area. In addition, the drug may lead to a decrease in potassium, sugar or sodium levels. However, usually adverse reactions appear very rarely and disappear after discontinuation of the drug.

Overdose

Excessive consumption of biseptol poses a risk of the following side effects:

increased drowsiness;
dizziness;
nausea;
vomit;
loss of appetite;
disturbance of consciousness;
hepatitis;
fever;
hematuria.

To cope with unpleasant symptoms, the drug should be discontinued and the stomach should be rinsed. The patient is also advised to drink plenty of fluids. His condition needs to be kept under control.

At chronic intoxication There is a risk of leukopenia with the medicine. Megaloblastic anemia and thrombocytopenia may also appear. Leucovorin helps eliminate these symptoms. It is taken 5-15 mg per day.

special instructions

For people prone to allergies, the drug is prescribed with great caution. With long-term use of the drug there is a risk of changes in blood counts. To minimize these threats, folic acid is prescribed in an amount of 3-6 mg per day.