Novinet: side effects and real prospects. Contraceptive pills "Novinet": reviews from doctors

Monophasic hormonal contraceptive drug for oral administration.
Drug: NOVINET®

Active substance of the drug: desogestrel, ethinylestradiol
ATX coding: G03AA09
KFG: Monophasic oral contraceptive
Registration number: P No. 014994/01-2003
Registration date: 05/23/03
Owner reg. cert.: GEDEON RICHTER Ltd. (Hungary)

The film-coated tablets are pale yellow, biconvex, disc-shaped, marked “P9” on one side and “RG” on the other side.
1 tab.
ethinylestradiol
20 mcg
desogestrel
150 mcg

Excipients: quinoline yellow (E104), -tocopherol, magnesium stearate, anhydrous colloidal silicon dioxide, stearic acid, povidone, potato starch, lactose monohydrate.

Shell composition: propylene glycol, macrogol 6000, hypromellose.

21 pcs. - blisters (1) - cardboard boxes.
21 pcs. - blisters (3) - cardboard boxes.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Novinet

A monophasic hormonal contraceptive for oral administration containing a combination of estrogen (ethinyl estradiol) and a progestin (desogestrel). Inhibits pituitary secretion gonadotropic hormones. The contraceptive effect is due to the effect on the hypothalamic-pituitary-ovarian system.

Desogestrel is a synthetic gestagen that, when taken orally, inhibits the synthesis of LH and FSH in the pituitary gland and, by preventing follicle maturation, effectively blocks ovulation. It has an antiestrogenic, weak androgenic (anabolic) effect, and does not have an estrogenic effect.

Ethinyl estradiol is a synthetic analogue of the follicular hormone estradiol, involved together with the hormone corpus luteum in the formation menstrual cycle. Prevents the maturation of an egg capable of fertilization.

The contraceptive effect is due, on the one hand, to a decrease in the susceptibility of the endometrium to the blastocyte, and on the other hand, to an increase in the viscosity of mucus in the cervix, which prevents the advancement of sperm.

The drug has a beneficial effect on lipid metabolism: increases plasma HDL levels without affecting LDL levels.

When taking the drug, the loss of menstrual blood is significantly reduced. Regular use of the drug normalizes the menstrual cycle and helps prevent the development of a number of gynecological diseases, including cancer.

Has a beneficial effect on skin, significantly improves the condition of the skin with acne vulgaris.

Pharmacokinetics of the drug.

Desogestrel

Suction

Desogestrel is quickly and almost completely absorbed from the gastrointestinal tract and is immediately metabolized in the liver and intestinal wall into 3-keto-desogestrel, which is a biologically active metabolite of desogestrel.

Cmax is reached after 1.5 hours and is 2 ng/ml. Bioavailability - 62-81%.

Distribution

3-keto-desogestrel binds to plasma proteins, mainly albumin and sex hormone binding globulin (SHBG).

Vd is 5 l/kg. Css is established by the second half of the menstrual cycle, when the level of 3-keto-desogestrel increases 2-3 times.

Metabolism

The products of further metabolism of ketodesogestrel are pharmacologically inactive; some of them are converted by conjugation into polar metabolites, primarily sulfates and glucuronides.

Removal

T1/2 is 38 hours. Metabolites are excreted in urine and feces (in a ratio of 6:4).

Ethinyl estradiol

Suction

Ethinyl estradiol is quickly and completely absorbed from the gastrointestinal tract. Cmax is reached 1-2 hours after taking the drug and is 80 pg/ml. The bioavailability of the drug due to presystemic conjugation and the “first pass” effect through the liver is about 60%.

Distribution

Ethinyl estradiol is almost completely bound to plasma proteins, mainly albumin.

Vd is 5 l/kg. Css is established by the 3-4th day of administration, while the level of ethinyl estradiol in the serum is 30-40% higher than after a single dose of the drug.

Metabolism

Presystemic conjugation of ethinyl estradiol is significant. Ethinyl estradiol and its metabolites in the form of sulfates and glucuronides are excreted into bile and enter the enterohepatic circulation. Clearance from blood plasma is about 5 ml/min/kg body weight.

Removal

T1/2 of ethinyl estradiol averages about 26 hours. About 40% is excreted in the urine and about 60% in feces.

Indications for use:

Oral contraception.

Dosage and method of administration of the drug.

The tablets are taken orally, at the same time of day, without chewing and with a small amount of liquid.

The drug is prescribed 1 tablet/day (if possible at the same time of day), starting from the 1st day of the menstrual cycle for 21 days. This is followed by a 7-day break, during which menstrual-like bleeding occurs. On the eighth day, resume taking tablets from the next package (even if the bleeding has not stopped yet). If the rules of administration are followed, the contraceptive effect is maintained during the 7-day break.

If the first tablet is taken on day 1 of the menstrual cycle, then additional methods contraception is not required. You can start taking pills from the 2-5th day of menstruation, but in this case, in the first cycle, you must use additional methods of contraception in the first 7 days of taking the pills.

If more than 5 days have passed since the start of menstruation, you should delay starting the drug until your next menstruation.

After childbirth, non-breastfeeding women can be prescribed the drug after 21 days. In this case, there is no need to use other methods of contraception. If the drug is prescribed later than 21 days after birth, then additional methods of contraception must be used in the first 7 days of administration. If in postpartum period sexual intercourse preceded oral contraception, then taking pills must wait until the first menstruation appears. Women who continue breast-feeding, the use of combined oral contraception, since taking the drug may reduce milk production.

When switching to Novinet after taking another estrogen-progestin hormonal contraceptive (calculated for 21 or 28 days of use), the first Novinet tablet should be taken the next day after completing the course of the previous drug. There is no need to use additional methods of contraception.

When switching to Novinet after taking a hormonal contraceptive containing only gestagen, the first Novinet tablet should be taken on the first day of the menstrual cycle; there is no need to use additional methods of contraception. If menstruation does not occur while taking the previous drug, you can start taking Novinet on any day of the cycle, but in this case, additional methods of contraception must be used in the first 7 days of use.

As additional methods of contraception, it is recommended to use a cervical cap with spermicidal gel, a condom, or abstain from sexual intercourse. Application calendar method less reliable as an additional method of contraception.

If it is necessary to delay menstruation, taking the pills should be continued without a 7-day break. In this case, intermenstrual bleeding may appear, but this does not reduce the contraceptive effect of the drug. Regular use of Novinet can be resumed after the usual 7-day break.

If you miss taking the drug, if from the moment last appointment no more than 12 hours have passed, then you need to take the missed tablet and then continue taking it at the usual time. If more than 12 hours have passed since the last pill was taken, then the reliability of contraception in this cycle is not guaranteed and the use of additional methods of contraception is recommended.

If you miss 1 tab. in the first or second week of the cycle you need to take 2 tablets. the next day and then continue regular use using additional methods of contraception until the end of the cycle. If you miss 1 tab. in the third week of the cycle, in addition to the listed measures, a 7-day break is excluded.

Due to the intake of a smaller dose of estrogen into the body due to missing pill(s), the likelihood of ovulation and/or development bloody discharge increases, therefore in such cases the use of additional methods of contraception is recommended.

If vomiting or diarrhea occurs after taking the drug, then absorption of the drug may be inadequate. If the symptoms stop within 12 hours, then you need to take 1 additional tablet from another package. After this, you should continue taking the tablets as usual. If symptoms continue for more than 12 hours, then it is necessary to use additional methods of contraception in the next 7 days.

Side effects of Novinet:

Severe side effects, which are extremely rare, requiring discontinuation of the drug

From the outside of cardio-vascular system: myocardial infarction, stroke, deep vein thrombosis lower limbs, thromboembolism of pulmonary vessels, increased blood pressure.

From the outside digestive system: cholestatic jaundice, cholelithiasis.

Other: exacerbation of systemic lupus erythematosus; in some cases - Sydenham's chorea, which disappears after discontinuation of the drug.

Other side effects are more common, but do not require discontinuation of the drug

From the reproductive system: intermenstrual bleeding, amenorrhea after discontinuation of the drug, changes in the nature of vaginal mucus, vaginal candidiasis, changes in the size of uterine fibroids, worsening of endometriosis, tension, pain, enlarged mammary glands, milk secretion, changes in libido.

From the digestive system: nausea, vomiting, gastralgia, hepatocellular adenoma.

Dermatological reactions: erythema nodosum, rash, generalized itching, chloasma (with long-term use).

From the side of the central nervous system: headache, migraine, mood lability, depression, hearing loss.

From the organ of vision: swelling of the eyelids, conjunctivitis, blurred vision, flickering before the eyes, increased sensitivity of the cornea (when wearing contact lenses).

On the metabolic side: fluid retention in the body, changes in body weight, decreased tolerance to carbohydrates.

From the laboratory parameters: the estrogenic component of Novinet tablets can change some indicators of liver, kidney, adrenal gland function, thyroid gland, the level of blood coagulation factors and fibrinolysis, lipoproteins and transport proteins.

Contraindications to the drug:

Pregnancy or suspicion of it;

Arterial hypertension is severe or medium degree heaviness;

Familial forms of hyperlipidemia;

Thromboembolism (including a history) or predisposition to it (myocardial infarction, cerebrovascular diseases (ischemic and hemorrhagic stroke), severe form of atherosclerosis);

IHD, decompensated heart defects, myocarditis;

Diabetic angiopathy (including retinopathy);

Severe liver diseases (including a history), cholestatic jaundice, hepatitis (before normalization of laboratory parameters and in the first 6 months after their normalization), jaundice during pregnancy or while taking corticosteroids, Dubin-Johnson syndrome, Rotor syndrome, cholelithiasis disease, liver tumor, porphyria;

Estrogen-dependent tumors or suspicion of them, breast and endometrial cancer, endometrial hyperplasia, endometriosis, breast fibroadenoma;

Genital bleeding of unknown etiology;

Systemic lupus erythematosus (including history);

Genital herpes, pregnancy herpes;

Severe skin itching;

Otosclerosis (aggravated during a previous pregnancy or while taking corticosteroids);

Hypersensitivity to the components of the drug.

With caution and only after a thorough assessment of the benefits and risks of use, the drug should be prescribed for diseases of the hemostatic system, heart failure (including a history), renal failure(including a history), epilepsy, migraine, at risk of developing an estrogen-dependent tumor, diabetes mellitus, sickle cell anemia (during infections or hypoxic conditions, taking an estrogen-containing drug can trigger thromboembolism), with severe depression (including a history).

Use during pregnancy and lactation.

Novinet is contraindicated for use during pregnancy. Taking Novinet should be stopped 3 months before the planned pregnancy. If pregnancy occurs, the drug should be discontinued.

Epidemiological studies have shown that among children, born by women who took hormonal contraceptives before pregnancy, the incidence of malformations does not increase. In cases of taking the drug for early stages No teratogenic effects were detected during pregnancy.

The use of Novinet is contraindicated during lactation (breastfeeding), because the drug reduces secretion breast milk, changes its composition. Besides, active substances excreted in small quantities in breast milk.

Special instructions for the use of Novinet.

Before starting to use the drug, it is necessary to conduct a general medical examination (detailed family and personal history, blood pressure measurement, laboratory research) And gynecological examination(including examination of the mammary glands, pelvic organs, cytological analysis cervical smear). A similar study during the period of taking the drug is carried out regularly, every 6 months.

The effectiveness of the drug Novinet is reduced if pills are missed, with vomiting and diarrhea, as well as with simultaneous administration with other drugs.

The effectiveness of Novinet may decrease if intermenstrual bleeding appears after several months of its use. If menstrual-like bleeding does not appear during the break, taking the pills can be continued only after pregnancy has been ruled out.

The risk of arterial or venous thromboembolic diseases increases with age, with smoking, with a family history of thromboembolic diseases, with obesity (body mass index above 30 kg/m2), with dyslipoproteinemia, with arterial hypertension, with heart valve defects, with atrial fibrillation, with diabetes mellitus, with prolonged immobilization.

If depression is associated with impaired tryptophan metabolism, then vitamin B6 can be used to correct it.

In the presence of resistance to activated protein C, hyperchromocysteinemia, deficiency of proteins C, S, deficiency of antithrombin III, the presence of antiphospholipid antibodies (anticardiolipins, lupus anticoagulants), the risk of developing thromboembolic diseases increases. Targeted treatment of the above conditions reduces the risk of blood clots.

Pregnancy poses a greater risk of blood clots than taking hormonal contraceptives.

Taking Novinet should be stopped immediately in the following cases:

New onset of severe headache or worsening of regular migraines;

Acute deterioration of visual acuity;

Suspicion of myocardial infarction or thrombosis;

A sharp increase in blood pressure;

The appearance of jaundice or hepatitis without jaundice, intense generalized itching;

The occurrence of epilepsy or increased frequency of epileptic seizures;

4 weeks before planned surgical intervention and in case of prolonged immobilization (taking Novinet can be resumed after 2 weeks from the moment of remobilization);

Development of pregnancy.

Impact on the ability to drive vehicles and operate machinery

No studies have been conducted to study the effect of Novinet on the abilities necessary to drive a car and operate machinery.

Drug overdose:

Symptoms: metrorrhagia. Taking the drug in high doses was not accompanied by the appearance of severe symptoms.

Treatment: in the first 2-3 hours after taking the drug in a high dose, gastric lavage is recommended. There is no specific antidote, treatment is symptomatic.

Interaction of Novinet with other drugs.

With simultaneous use of Novinet with antispasmodics, phenobarbital derivatives, antibiotics (tetracycline, ampicillin, rifampicin, isoniazid, neomycin, penicillin, chloramphenicol), carbamazepine, phenylbutazone, analgesics, anxiolytics, activated carbon, sulfonamides, nitrofurans, antimigraine drugs, griseofulvin, laxatives and some medicinal plants(for example, St. John's wort) it is possible to change the nature of menstruation and reduce the contraceptive effect of Novinet.

Novinet, when used simultaneously, reduces the effectiveness of oral anticoagulants, anxiolytics (diazepam), tricyclic antidepressants, guanethidine, theophylline, caffeine, vitamins, clofibrate, glucocorticosteroids, paracetamol.

When Novinet is used simultaneously with oral hypoglycemic drugs or insulin, the condition may be impaired. carbohydrate metabolism, because Novinet may reduce carbohydrate tolerance and increase the need for insulin or oral hypoglycemic agents, which may require dose adjustment.

Terms of sale in pharmacies.

The drug is available with a prescription.

Terms of storage conditions for the drug Novinet.

The drug should be stored out of the reach of children at a temperature of 15° to 30°C. Shelf life - 3 years.

If you have any difficulties or problems, you can contact a certified specialist who will definitely help!

Novinet is a monophasic drug, that is, all tablets in the blister contain the same dose of hormones. Each Novinet tablet contains 20 mcg (0.02 mg) ethinyl estradiol and 150 mg desogestrel.

One Novinet cardboard box contains one or three blisters of tablets. One blister contains 21 tablets (for 3 weeks of use).

ATTENTION: The drug has contraindications. Do not start using this drug without preliminary consultation with a doctor.

Advantages of Novinet

Novinet is a birth control pill. latest generation. The hormone content in Novinet tablets is so low that taking the drug causes virtually no side effects.

Regular use of Novinet for at least 3 months reduces the symptoms of premenstrual syndrome (PMS), eliminates chest pain shortly before menstruation,. Novinet can be recommended for girls who have an irregular menstrual cycle.

Long-term use of Novinet reduces the risk of hormonal disorders (mastopathy), oncological diseases(ovarian cancer, uterine cancer).

Admission rules

  • The first tablet can be taken on day 1 of the menstrual cycle (that is, on the first day of menstruation). In this case, the tablets begin to act immediately and you do not have to use additional funds contraception.
  • If you start taking Novinet from the 2-5th day of your period, the contraceptive effect will occur only after 7 days of daily use. Condoms should be used for the first 7 days.
  • It is recommended to take Novinet tablets at the same time every day (no matter what time of day). This way the effect of the tablets will be the highest.
  • All Novinet tablets contain the same dose of hormones, so if you mix up the tablets, nothing bad will happen. The main thing is to drink one tablet once a day.
  • After you take the last 21 tablets in the blister, take a week break. During these seven days off the pills, you may experience menstrual-like bleeding (periods).
  • During the 7-day break from taking Novinet, there is no need to take additional protection. This only applies if you start taking the pills again after the week-long break.
  • Regardless of whether you had menstruation during the break, you should take the first tablet from the new blister on day 8.

How to switch to Novinet from another OK?

You can switch to Novinet from another oral contraceptive. If in the packaging of the previous oral contraceptives there were 21 tablets, then take the first tablet of Novinet on the 8th day after a week break.

If one blister of previous oral contraceptives contained 28 tablets, then start taking Novinet the next day after finishing all the tablets in the previous blister.

How to switch to Novinet from a hormonal patch (Evra) or a vaginal ring?

You can switch to Novinet from other hormonal contraceptives. To do this, take the first Novinet tablet on the day when the vaginal ring was removed, or on the day when you were scheduled to insert a new ring, or stick on a new patch.

How to switch to Novinet from an intrauterine device (IUD)?

You can take your first Novinet tablet on the day you remove intrauterine device. During the next week after starting Novinet, it is recommended to use additional methods of contraception to avoid pregnancy.

How to start taking Novinet after an abortion?

If you have an abortion before 12 weeks of pregnancy, the first Novinet tablet should be taken on the day of the abortion. If you plan to start taking Novinet later (not on the day of your abortion) and you have already had unprotected sex, then you should only start taking the pills if you are sure that you are not pregnant again.

In case of abortion at a period of more than 12 weeks, the first Novinet tablet can be taken 21-28 days after the abortion. If you start taking Novinet later than this period, you will need to use additional contraception for another 7 days. If you have unprotected sex in the days after an abortion, you can start taking Novinet only when you are sure that you are not pregnant.

How to start taking Novinet after childbirth?

After giving birth, you can start taking Novinet in the first month (if you are not breastfeeding), or when you stop breastfeeding. If you are not breastfeeding, then the first Novinet tablet should be taken 21-28 days after birth. If, after giving birth, before starting to take Novinet, you had unprotected sex, then you are allowed to start taking Novinet when you are sure that pregnancy has not occurred.

What to do if you miss a Novinet tablet?

If the delay in taking Novinet lasted less than 12 hours (and less than 36 hours have passed since taking the previous pill), then the effect of the pills is preserved. Take the missed pill as soon as possible. There is no need for additional protection.

If you are more than 12 hours late, the effectiveness of the pills is reduced. Pay attention to the number of the missed pill - it will tell you what to do next:

  • 1 to 7 tablets: Take the missed tablet as soon as possible, even if you have to take 2 tablets at the same time. In the next 7 days, it is recommended to use additional protection methods (condoms).
  • 8 to 14 tablets: Take the missed tablet as soon as possible, even if you need to take two tablets at the same time. You do not have to use additional contraception if you have taken all your pills on time for the previous 7 days. Otherwise, you should take additional precautions for another week after taking Novinet to avoid pregnancy.
  • 15 to 21 tablets: Take the missed Novinet tablet as soon as you remember, even if this means taking two tablets at the same time. Continue taking the tablets as usual, but after finishing one blister, immediately start taking the next one. This way you skip the week between packs. If you took all Novinet tablets on time during the previous 7 days before the missed period, then there is no need for additional protection. Otherwise, it is recommended to use additional contraception for a week after the missed date.

What should I do if I missed several Novinet tablets?

If you miss 2 Novinet tablets in a row, pay attention to which tablets you missed. If these are tablets of the first or second week of taking (from 1 to 14), then take 2 tablets as soon as you remember about the omission and 2 more tablets the next day. Then take one tablet per day as usual until the pack runs out. Use additional contraception for another 7 days after resuming taking the pills.

If you missed two tablets in a row in the 3rd week of taking it (from 15 to 21), then there are two options: 1. continue taking Novinet one tablet per day until the package runs out and then, without taking a 7-day break, start new packaging. At the same time, use additional contraception for another 7 days after the missed period.
2. throw away the current (unfinished) package and start taking new packaging from the first tablet (one tablet per day, as usual). In this case, you need to use additional contraception for another 7 days after the missed date.

If you miss 3 Novinet tablets in a row, throw away the current pack of tablets and start a new pack with the first tablet. Use additional contraception for another 7 days. You will have an increased risk of pregnancy, so if your period does not come during the next break, contact your gynecologist.

If you are not sure what to do in your situation, use additional contraception until you talk to your doctor. In any case, if you miss two or more tablets, be sure to use additional protection (using condoms) for at least 7 days.

1-2 days after missing the pills, you may experience spotting or breakthrough bleeding, similar to your period. This is not dangerous and is associated with Novinet passes. Continue taking the pills according to the instructions and the discharge will stop.

What reduces the contraceptive effect of Novinet?

The contraceptive effect of Novinet can be reduced by vomiting, diarrhea, taking large doses of alcohol, or taking certain medications. Read more about this here:

How to delay menstruation with Novinet?

If you need to postpone your period, then after finishing one blister of Novinet, start a new blister the next day without taking a week's break. Menstruation will be delayed by 2-4 weeks. BUT: bloody spotting may appear in the middle of the next package. It's not scary.

Please note: you can postpone your periods only if you have taken Novinet for at least one month before the postponed menstruation.

What to do if brown discharge appears while taking Novinet?

Spotting and spotting when taking Novinet is sometimes normal. For example, such discharge does not cause concern if you have just started taking pills (on the first or second package), in the middle of the package and in the first few days after starting the next pack of Novinet.

If before the appearance brown discharge If you were late or missed taking pills, the contraceptive effect of Novinet may be reduced, which means you should use condoms in case of sexual intercourse.

What to do if you don’t have your period while taking Novinet?

    If in the previous month you missed taking Novinet and had unprotected sex, then stop taking the pills. Do not start taking Novinet until you are sure that you are not pregnant.

    If in the previous month you took the pills according to the rules, did not skip, or were not sexually active, then start taking a new blister on the 8th day, even if your period did not come. If there is no menstruation during the next week's break, it is recommended to visit a gynecologist.

What should I do if I become pregnant while taking Novinet?

It is not dangerous for the unborn child. If you find yourself pregnant, stop taking the pills immediately and consult your doctor. As a rule, taking Novinet does not affect the development of the fetus, so there is no need to have an abortion. If you plan to continue your pregnancy, start taking it as soon as possible.

Taking Novinet before surgery

If you are having surgery, you should stop taking Novinet at least 4 weeks before. surgical intervention. If the operation is urgent, tell your doctor that you are taking birth control pills.

Novinet thickens the blood, promoting the formation of blood clots (thrombi). If your doctor knows you are taking birth control pills, he will prescribe you blood thinners.

You can resume taking Novinet 14 days after you are able to walk independently after surgery.

How often should you visit a gynecologist while taking Novinet?

Even if nothing bothers you, visit your gynecologist at least once a year.

Among the many ways to prevent pregnancy, all larger number women prefer oral contraceptives. Novinet is one of wide range birth control pills, which have fairly strong contraceptive qualities, comfortable conditions for taking and a low percentage of side effects.

As a nice extra, this drug helps regulate the menstrual cycle and treats some gynecological diseases. Birth control pills Novinet is a single-phase pill containing the same dose of estrogen and progestin hormones every day, which suppress ovulation.

How Novinet works

The hormones contained in the drug - desogestrel and ethinyl estradiol - are of artificial origin, almost similar to natural gestagen and estrogen, but show greater bioactivity. Their combination does not allow the pituitary gland to synthesize FSH hormones and LH, which prevents the maturation of the next egg, and, accordingly, ovulation and further conception cannot occur.

Additionally, this contraceptive makes mucus in cervical canal thick, which prevents sperm from penetrating the uterus and meeting the egg.

Novinet helps:

  • regulate the frequency of menstruation by creating an artificial cycle;
  • reduce their intensity and pain;
  • ease the course of PMS;
  • get rid of acne and improve skin condition;
  • reduce the likelihood of developing certain diseases of the female genital area.

Since estrogen is introduced into the drug in the minimum effective dose, then side effects associated with this hormone (chest pain, nausea, extra pounds), are very rare. All components of Novinet penetrate and settle in all organs within 1-2 hours, and estrogen settles in adipose tissue. Completely broken down metabolic products are filtered and excreted from the body by the kidneys.

The downside of Novinet

On the contraceptive market, the drug is positioned as having virtually no side effects. However, they can still appear, albeit with a low probability. Most often, consumers complain of mood swings and even depression, increased blood pressure, nausea and vomiting, exacerbations ulcerative colitis, weight changes, skin rashes, increased sensitivity of the mammary glands, abnormal vaginal bleeding, eye hypersensitivity to contact lenses, decreased libido.

As a rule, after 1-3 months the body adapts to Novinet, and side effects disappear without additional treatment.

The most severe consequences of not taking the drug by the body are serious hypertension, blood clots and vein blockage, myocardial infarction, hearing loss, hemolytic-uremic syndrome, impaired hemoglobin synthesis (porphyria), exacerbation rheumatic diseases. Such side effects from Novinet require immediate cessation of its use. It should be noted that smoking in women greatly contributes to the development of thrombosis.

Reception nuances

A pack of Novinet is designed for a month of use. The days of the week are written on the back of the package (though only for one, which can be considered a design flaw) - this makes it easier to control the pill intake. For yourself, you can write down the date of taking the first pill on the pack, repeat after 10 days, this will eliminate the need to count down the date of the current dose every day.

Start taking the drug with the start of the next menstrual cycle. The hours you take the first pill will become the hours you take all subsequent pills, so before you start using this pill, contraceptive drug it is advisable to choose the most the right time, when the probability of forgetting about taking the next pill is very small. Users recommend keeping a pack of Novinet in a place where a woman is every day at the same time, performing routine actions - for example, near a toothbrush. You can set an alarm for the time you take the drug.

After completing 21 tablets from the pack, skip 7 days, during which the next period should come. Exactly after a week (even if the “critical days” are still ongoing), you should start a new pack of pills. The instructions for the drug advise you to wait until the start of your next period if the previous one ended more than 5 days ago. If a woman takes the first pill from day 2 to day 5 of the cycle, she needs additional protection for the entire next week.

The contraceptive effect of Novinet also decreases after vomiting and diarrhea - in such cases it is advisable to use condoms. If all conditions of administration are strictly observed, a persistent contraceptive effect occurs on days 7-14 of the cycle. Fertility is restored within 3 months after discontinuation of the drug. The chances of conceiving a child in the first month after stopping Novinet are very high.

If well tolerated, Novinet can be taken without interruption for an unlimited period. If you are planning a pregnancy, the drug should be discontinued.

When your scheduled periods do not come while taking the drug, you should donate blood for hCG or do a pregnancy test. If pregnancy is confirmed, the woman should not fear problems with the health of the unborn child - negative influence This contraceptive has not been established for the fetus at the beginning of pregnancy.

Novinet after special events

New mothers have an appointment this drug with the beginning of the restored menstrual cycle or after three weeks after childbirth (provided artificial feeding child). You must first consult a gynecologist. If treatment is started with the onset of menstruation, additional measures contraception is not required, and if earlier, the first week should be protected by other methods.

If a woman has suffered a miscarriage or had an induced abortion, a fresh pack of Novinet should be started immediately on the day of the incident. In this case, additional measures (meaning barrier contraception– condoms or abstinence in general) is not required.

Novinet is not suitable for those giving birth who are breastfeeding, as the hormones contained in it help reduce milk production and deteriorate its taste.

In cases where a woman has previously taken other oral contraceptives, the instructions recommend starting Novinet according to the usual regimen after a 7-day break. It is allowed to take the drug without interruption for menstrual bleeding.

If, in all the situations described, when you start taking this oral contraceptive, severe headaches begin, your blood pressure rises sharply, your vision decreases, or swelling of your legs appears, you should immediately stop Novinet and contact your gynecologist for advice.

At planned operations It is recommended to stop using the drug a month before the scheduled day. If there is a vital need to delay the onset of menstruation, you can immediately start drinking a new pack of Novinet without taking a week’s break, then there will be no menstruation during this cycle.

What to do when you forgot to take a pill?

If a woman thinks about her health, she will take all measures so as not to forget to swallow the next dose of contraception on time. However, there are situations when a “puncture” still happens. In these cases, you must act according to the instructions for the drug, depending on the time of omission.

If the delay is less than 12 hours, you should immediately take the missed tablet. During the specified time, the contraceptive effect is maintained; additional contraceptives are not required. In case of more long delay reception, you need to take the missed pill and all the subsequent ones according to the scheme, but before the end of the pack, additional backup may be required.

When a woman forgot about the pill during the first or second week of the menstrual cycle, next appointment It is recommended to take both the missed and the current pills, all subsequent ones - according to the established schedule. If you missed several doses, take two tablets in the following days.

In cases where the pill is not received in the third week of the cycle, in addition to the above measures, you should abandon the week-long break and take Novinet one pill on these days.

A woman can “pay” for forgetfulness with small bloody discharge from the vagina on days you missed pills.

For whom Novinet is contraindicated

Like anyone medicine, this contraceptive has a number of contraindications:

  1. neurological pathology;
  2. severe pathology of the heart, liver, kidneys;
  3. tumors of any location;
  4. smoking (significantly increases the risk of thrombosis) and age after 35 years (premenopausal hormonal changes begin);
  5. diabetes mellitus with vascular complications;
  6. tendency to thrombosis;
  7. previous strokes or heart attacks.

In addition, it should be borne in mind that the effectiveness of the drug can be greatly reduced when used simultaneously with antibiotics and a number of other drugs; the attending physician should be warned about this at the time of prescription.

To drink or not to drink

Having studied the instructions for the drug and read reviews on the Internet, you can be convinced that Novinet is a fairly powerful means of contraception; by strictly observing the conditions of use, you can achieve a good contraceptive effect, despite a number of contraindications. The main thing is to see your treating gynecologist on time and undergo periodic tests, including hormonal status indicators. The doctor will determine whether this contraceptive is suitable for a particular woman or not.

Last update of the description by the manufacturer 07/15/2014

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Nosological classification (ICD-10)

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Compound

pharmachologic effect

pharmachologic effect- estrogen-progestogenic, contraceptive.

Directions for use and doses

Inside. Taking pills starts on the 1st day of the menstrual cycle and takes 1 tablet. per day for 21 days, if possible at the same time of day. After taking the last tablet from the package, take a 7-day break, during which menstrual-like bleeding occurs due to drug withdrawal. The next day after a 7-day break (4 weeks after taking the 1st tablet, on the same day of the week), resume taking the drug from the next package, also containing 21 tablets, even if the bleeding has not stopped. This pill regimen is followed as long as there is a need for contraception. If the rules of administration are followed, the contraceptive effect is maintained during the 7-day break.

1st dose of the drug

Reception of the 1st table. should start on the 1st day of the menstrual cycle. In this case, it is not necessary to use additional methods of contraception. You can start taking pills from the 2-5th day of menstruation, but in this case, in the 1st cycle of using the drug, you must use additional methods of contraception in the first 7 days of taking the pills. If more than 5 days have passed since the start of menstruation, you should delay starting the drug until your next menstruation.

Taking the drug after childbirth

Women who are not breastfeeding can start taking the pills no earlier than the 21st day after giving birth, after consulting with their doctor. In this case, there is no need to use other methods of contraception. If you have already had sexual contact after giving birth, then you should wait until your first menstruation to take the pills. If a decision is made to take the drug later than 21 days after birth, then additional methods of contraception must be used in the first 7 days.

Taking the drug after an abortion

After an abortion, in the absence of contraindications, you should start taking pills from the 1st day, and in this case there is no need to use additional methods of contraception.

Switching from another oral contraceptive

Taking Novinet ® after a contraceptive (with 30 mcg ethinyl estradiol) containing 21 tablets. 1st table Novinet ® is recommended to be taken the next day after completing the course of the previous drug. There is no need to take a 7-day break or wait for the start of menstruation. There is no need to use additional methods of contraception.

Taking Novinet ® after a contraceptive containing 28 tablets. The next day after the tablets in the package run out, you should start a new package of Novinet ® .

Taking Novinet ® after using a contraceptive containing only progestogen (mini-pill). 1st table Novinet ® should be taken on the 1st day of the cycle. There is no need to use additional methods of contraception.

If menstruation does not occur while taking the mini-pill, then after excluding pregnancy, you can start taking Novinet ® on any day of the cycle, but in this case, additional methods of contraception must be used in the first 7 days.

In the above cases, the following are recommended as additional methods of contraception: non-hormonal methods: use of a cervical cap with spermicidal gel, a condom, or abstaining from sexual intercourse. The use of the calendar method in these cases is not recommended.

Delay of the menstrual cycle

If there is a need to delay menstruation, you must continue taking the tablets from the new package without a 7-day break, according to the usual regimen. When menstruation is delayed, breakthrough or spotting bleeding may appear, but this does not reduce contraceptive effect drug. Regular use of Novinet ® can be resumed after the usual 7-day break.

Missed pills

If a woman forgot to take a pill on time, and no more than 12 hours have passed since the omission, she just needs to take the forgotten pill, and then continue taking it at the usual time. If more than 12 hours have passed between taking pills, this is considered a missed pill, the reliability of contraception in this cycle is not guaranteed and the use of additional methods of contraception is recommended.

If you miss one tablet on the 1st or 2nd week of the cycle, you must take 2 tablets. the next day and then continue regular use using additional methods of contraception until the end of the cycle. If you miss a pill in the 3rd week of the cycle, you must take the forgotten pill, continue taking it regularly and do not take a 7-day break. It is important to remember that due to the minimum dose of estrogen, the risk of ovulation and/or spotting increases if a pill is missed, and therefore the use of additional methods of contraception is recommended.

Directions for vomiting or diarrhea

If vomiting or diarrhea occurs after taking the drug, then absorption of the drug may be inadequate. If the symptoms stop within 12 hours, then you need to take 1 more tablet. additionally. After this, you should continue taking the tablets as usual. If symptoms continue for more than 12 hours, then it is necessary to use additional methods of contraception during vomiting or diarrhea and for the next 7 days.

Release form

Film-coated tablets, 0.02 mg + 0.15 mg. In a blister of aluminum/PVC/PVDC, 21 pcs. 1 or 3 blisters in a cardboard box.

A contraceptive drug based on two hormonal active ingredients. With regular and correct intake provides a high percentage of protection against unwanted pregnancy. It is also available in large packaging, which is more economical for patients. For getting reliable protection The tablets must be taken in a specific order. Unlike some other hormonal contraceptives, Novinet assumes a 7-day break during menstrual bleeding.

Dosage form

The drug Novinet is available in a single form - tablets for oral administration. They belong to the clinical and pharmacological group of monophasic oral contraceptives and can only be used by women reproductive age. The manufacturer of the drug is the pharmacological company JSC Gedeon Richter, Hungary. The tablets are packaged in blister packs No. 21. The package contains 1 or 3 blisters, as well as an insert with information about the drug.

Description and composition

Novinet is a combined hormonal contraceptive pill. Taking pills has a systemic effect on reproductive system women, inhibits ovulation, prevents the penetration of sperm through the cervical mucus. The tablets have the ability to suppress the pituitary secretion of luteotropin and follitropin, thereby making vaginal secretions more viscous.

The active components of the drug are synthetic hormones - ethinyl estradiol and progestogen, which suppress ovulation. The tablets contain 20 mcg ethinyl estradiol and 150 mcg desogestrel, as well as auxiliary components. Externally, the tablets are enteric-coated, light yellow in color, and round in shape.

Pharmacological group

Novinet tablets, which contain synthetic hormones, have a pronounced contraceptive effect, which consists of inhibiting the synthesis of gonadotropins and suppressing ovulation. Systematic use of tablets allows:

  • increase the viscosity of cervical mucus;
  • slow down the movement of sperm through the cervical canal;
  • change the condition of the endometrium;
  • prevents implantation of a fertilized egg.

Ethinyl estradiol is an analogue of endogenous estradiol, which is normally synthesized by the body and is responsible for the functioning of the female reproductive and reproductive system. Desogestrel, the second component of the drug, has gestagenic and antiestrogenic properties, as well as androgenic and anabolic activity. Clinical trials showed that taking pills can increase the concentration of lipoproteins high density(HDL) in the blood plasma, without affecting low density (LDL). Taking the medicine can not only protect against unwanted pregnancy, but also reduce the amount of menstrual blood during pregnancy, normalize the menstrual cycle, and reduce the appearance of acne.

Indications for use

Novinet tablets belong to hormonal contraceptives which help protect a woman from unwanted pregnancy.

For adults

The drug is used only in gynecology. The main purpose of taking pills may be:

  • contraception;
  • acne due to hormonal changes;
  • complex treatment of the uterus;
  • uterine fibroids;
  • ovarian cyst.

If there are benign or malignant tumors in the pelvic organs, taking tablets can only be used in combination with other medicines. If the main purpose of administration is contraception, then the drug will be the basis for systemic treatment.

For children

The drug is not used in pediatrics.

Women during pregnancy and lactation cannot use Novinet tablets.

Contraindications

The hormonal drug Novinet has a number of contraindications that you need to familiarize yourself with before taking them:

  • risk of arterial thrombosis;
  • thrombophlebitis;
  • pathologies of the heart and blood vessels;
  • liver and kidney diseases;
  • vaginal bleeding of unknown cause;
  • pregnancy or breastfeeding;
  • increased sensitivity to the composition.

Applications and dosages

Novinet tablets can only be taken as prescribed by a gynecologist. The dosage of the medicine, frequency and duration of administration directly depends on the period and condition of the female body.

  1. first dose of pills;
  2. taking medication after an abortion in the first trimester;
  3. taking pills after childbirth or abortion in the second trimester;
  4. as a replacement for another contraceptive;
  5. delay in the onset of menstruation.

When taking pills, it is important not only to adhere to the recommended dose, but also not to miss taking them. For achievement therapeutic effect, concentration active ingredients in the blood should not be disturbed.

For adults

The tablets should be taken in the order indicated on the blister. The first tablet should be taken from the 1st day of the menstrual cycle, 1 tablet per day, lasting 21 days. Doctors recommend taking the medicine at the same time of day. After taking the last tablet from the blister (after 21 days), you need to take a week's break, during which menstrual bleeding will begin. After a 7-day break, the tablets must be taken again using a new blister (21) tablets. You need to take the pills until you need contraception.

This pill regimen should be followed by a woman who wants to protect herself from an unwanted pregnancy. In other cases, the doctor must prescribe the regimen individually for each patient.

If while taking the pills there is a need to delay menstruation, you do not need to take a 7-day break. However, in such cases, spotting bleeding may occur. Gynecological doctors recommend adhering to the prescribed pill regimen, which will help reduce the risk of adverse reactions.

For children

The drug cannot be prescribed to children and adolescents.

For pregnant women and during lactation

Novinet tablets are not used for nursing or pregnant women.

Side effects

After taking the drug, there is a risk of developing side effects, including:

  • spotting bleeding not associated with menstruation;
  • inflammation of the inner vaginal wall;
  • nausea, ;
  • skin rash;
  • headache;
  • migraine;
  • weight gain.

Adverse reactions of the body after taking the drug are quite common, so taking the drug should always be agreed with your doctor.

Interaction with other drugs

Novinet tablets can be used in combination with other medications, but as the instructions for use indicate, some of them can reduce the effectiveness of oral contraceptives and increase the risk of uterine bleeding.

special instructions

  1. Before taking the drug, you need to study the instructions and consult a gynecologist.
  2. Contraceptives can be used after a thorough examination.
  3. At the first signs of intolerance to the drug, you should consult a doctor.
  4. The risk of becoming pregnant when taking Novinet is 0.05%, which allows us to consider this drug one of the reliable methods of contraception.
  5. The active components of the drug can affect various laboratory parameters, so if they are used, you should warn your doctor.

Overdose

If the dose of the drug is exceeded, there is a high risk of side effects, including:

  • nausea;
  • bloody discharge from the vagina.

At the first signs of an overdose, you need to take it as quickly as possible and seek medical help.

Storage conditions

You can buy Novinet tablets at the pharmacy without a doctor's prescription. The shelf life is 3 years from the date of issue. The drug should be stored away from direct sunlight and away from children. The optimal temperature for storage is from +15 to +30° C.

Analogues

The pharmacological market provides a fairly large range of drugs that can compete with Novinet. All drugs are divided into structural ones, that is, those that have an identical composition or therapeutic effect. Common analogues include:

  • – hormonal drug based on two active components - ethinyl estradiol and desogestrel with a pronounced contraceptive effect. Taking the drug suppresses the synthesis of hormones and the ovulation process.
  • Mercilon - combined contraceptive drug, containing gestagen and estrogen.
  • – monophasic contraceptive for oral use. Unlike analogues, it reduces the risk of developing cancers And inflammatory processes in the pelvic organs.

Drugs from the group of contraceptives can only be prescribed by a gynecologist. Self-medication can be harmful to a woman’s health.

Price

The cost of Novinet is on average 654 rubles. Prices range from 254 to 1320 rubles.

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