Dosage form
Pills
Composition
One tablet contains
active substances: paracetamol 500 mg
caffeine anhydrous 30 mg
phenylephrine hydrochloride 10 mg
chlorpheniramine maleate 2 mg,
excipients: colloidal anhydrous silicon dioxide, crimson dye 4R (E124), corn starch, povidone (K-30), sodium methyl parahydroxybenzoate, magnesium stearate, purified talc, sodium starch glycolate, purified water.
Description
Round flat pink tablets without a shell with dark pink and white splashes with beveled edges and a dividing line on one side.
Pharmacotherapeutic group
Analgesics. Other analgesics-antipyretics. Anilides. Paracetamol in combination with other drugs.
ATX code N02BE51
Pharmacological properties"type =" checkbox ">
Pharmacological properties
Pharmacokinetics
After oral administration, paracetamol is rapidly absorbed from gastrointestinal tract(Gastrointestinal tract), mainly in small intestine... After a single dose of 500 mg maximum concentration in blood plasma (Cmax) is reached within 60 minutes and is about 16 μg / ml, then gradually decreases and after 6 hours is 11-12 μg / ml. The blood protein binding is less than 10%. It is excreted in the urine mainly in the form of glucuronide and sulfate conjugates.
Caffeine is metabolized in the liver (97%) to 1,7-methylxanthine,
1,7-dimethylmethylxanthine and 1,3-dimethyl uric acid, which are excreted in the urine.
After oral administration, phenylephrine is poorly absorbed from the gastrointestinal tract. It is metabolized with the participation of MAO in the intestinal wall and during the "first pass" through the liver. The bioavailability of phenylephrine is low.
Chlorpheniramine penetrates well into various tissues and through the blood-brain barrier. It is metabolized in the liver by methylation. It is excreted in the form of metabolites and unchanged by the kidneys and gastrointestinal tract.
Pharmacodynamics
Rinza® has analgesic, antipyretic and anti-allergic effects due to the active substances that make up the drug.
Paracetamol has an analgesic and antipyretic effect: reduces pain syndrome observed with colds - sore throat, headache, muscle and joint pain, reduces high fever... The mechanism of action is associated with the suppression of the synthesis of prostaglandins, mainly in the center of thermoregulation in the hypothalamus.
Caffeine has a stimulating effect on the central nervous system(CNS), which leads to increased mental and physical performance.
Phenylephrine hydrochloride is an α1-adrenergic agonist. Has a vasoconstrictor effect, reduces edema and hyperemia of the mucous membranes upper divisions respiratory tract and paranasal sinuses nose.
Chlorpheniramine maleate - a blocker of histamine H1 receptors, has an antiallergic effect, reduces swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, eliminates itching in the eyes and nose, reduces exudative manifestations.
Indications for use
Symptomatic treatment:
ARVI ( febrile syndrome, pain syndrome, rhinorrhea)
Allergic rhinitis
Other colds accompanied by rhinitis, nasal congestion, headache, fever, chills, pain in joints, muscles.
Method of administration and dosage
Side effects"type =" checkbox ">
Side effects
Allergic reactions: skin rash, itching, urticaria, angioedema.
From the nervous system: dizziness, sleep disturbance, irritability.
From the side of cardio-vascular system: increase blood pressure, tachycardia.
From the side digestive system: nausea, vomiting, pain in the epigastric region, dryness of the oral mucosa, hepatotoxic effect.
From the senses: mydriasis, paresis of accommodation, increased intraocular pressure.
From the side of hematopoiesis: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.
From the urinary system: urinary retention, nephrotoxicity ( renal colic, glucosuria, interstitial nephritis, papillary necrosis).
Others: bronchospasm.
Serious skin reactions:
Very rarely:
Acute generalized exanthematous pustulosis (OGEP). Acute condition with the development of pustular eruptions. It is characterized by fever and diffuse erythema, accompanied by burning and itching. Swelling of the face, hands and mucous membranes may occur;
Stevens-Johnson syndrome (SJS) (malignant exudative erythema). A severe form of erythema multiforme, in which blisters appear on the mucous membrane of the mouth, throat, eyes, genitals, other areas of the skin and mucous membranes;
Toxic epidermal necrolysis (TEN, Lyell's syndrome). The syndrome is a consequence of extensive apoptosis of keratinocytes, which leads to the detachment of large areas of skin at the sites of the dermoepidermal junction. The affected skin looks like scalded with boiling water.
If you notice one of the above side effects, you should stop taking the drug and consult a doctor immediately!
Contraindications
Hypersensitivity to paracetamol and other components that make up the drug
Taking other drugs containing substances that make up Rinza®
Severe atherosclerosis coronary arteries
Arterial hypertension
Diabetes
Concomitant use of tricyclic antidepressants, monoamine oxidase inhibitors, beta-blockers
Pregnancy, lactation period
Children under 12 years of age
Alcoholism
With caution - with thyrotoxicosis, pheochromocytoma, bronchial asthma, chronic obstructive pulmonary disease, emphysema, chronic bronchitis, glucose-6-phosphate dehydrogenase deficiency, blood diseases, congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), hepatic and / or renal failure, angle-closure glaucoma, hyperplasia prostate the drug can be used with caution after consulting a doctor.
Drug interactions"type =" checkbox ">
Drug interactions
Enhances the effects of monoamine oxidase inhibitors, sedatives, ethanol.
When taken with digoxin or other cardiac glycosides, the risk of arrhythmias and myocardial infarction may increase.
Antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives - increase the risk of urinary retention, dry mouth, constipation. Glucocorticosteroids increase the risk of developing glaucoma. Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatitis toxic action... Metoclopramide and domperidone increase, and cholestyramine reduces the rate of absorption of paracetamol. Paracetamol reduces the effectiveness of uricosuric drugs. With the simultaneous administration of Rinza® with barbiturates, diphenin, carbamazepine, rifampicin and other inducers of liver microsomal enzymes, the risk of developing the hepatotoxic effect of paracetamol increases. In most patients on long-term warfarin, infrequent use of paracetamol usually has little or no effect on the international normalized ratio (INR). However, with prolonged regular use, paracetamol enhances the effect of indirect anticoagulants (warfarin and other coumarin derivatives), which increases the risk of bleeding. A single high dose of caffeine increases the excretion of lithium by the kidneys. Abrupt termination ingestion of caffeine can lead to an increase in serum lithium concentration.
Chlorpheniramine concurrently with monoamine oxidase inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia.
Phenylephrine when taken with monoamine oxidase inhibitors can increase blood pressure. Phenylephrine reduces the effectiveness of beta-blockers and antihypertensive drugs. Tricyclic antidepressants increase the adrenomimetic effect of phenylephrine, the simultaneous administration of halothane increases the risk of developing ventricular arrhythmias... Reduces the hypotensive effect of guanethidine, which, in turn, enhances the alpha-adrenostimulating activity of phenylephrine.
Application during pregnancy and during breastfeeding
Due to the lack of clinical data, the safety of using the drug during pregnancy and during breastfeeding has not been established, therefore, the appointment of the drug in this category of patients is contraindicated.
special instructions"type =" checkbox ">
special instructions
During the period of treatment, one should refrain from taking alcohol, sleeping pills and anxiolytic (tranquilizers) drugs. Do not take with other medicines containing paracetamol.
If the symptoms of the disease worsen or persist after 5 days of using the drug, you should stop taking it and consult your doctor.
The drug may cause drowsiness.
If medicine has become unusable or the expiration date has expired - do not dispose of it in waste water or outdoors! Place the medicine in a bag and put it in the trash can. These measures will help protect the environment!
Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms
The drug may cause drowsiness. During the period of treatment, it is necessary to refrain from driving vehicles and doing other potentially dangerous species activities requiring increased concentration attention and speed of psychomotor reactions.
Overdose
In case of overdose, consult a doctor immediately. Fast rendering medical care is critical even if you do not see any signs or symptoms.
Symptoms of acute overdose: abdominal pain, vomiting, flushing, fever, chills, agitation, insomnia, irritability, loss of appetite, weakness, tremor, increased muscle tone, altered consciousness, delirium, hallucinations, increased blood pressure followed by hypotension, tachycardia , tachypnea, increased urine output, hypokalemia, hyponatremia, hyperglycemia, metabolic acidosis, convulsions, myoclonus and rhabdomyolysis, supraventricular and ventricular arrhythmias.
Symptoms chronic intoxication caffeine "caffeinism": irritability, insomnia, anxiety, emotional lability, chronic pain in a stomach.
Chlorphenamine
Symptoms: depression of the central nervous system, hyperthermia, anticholinergic syndrome (mydriasis, flushing of the face, fever, dry mouth, urinary retention, intestinal paresis), tachycardia, hypotension, hypertension, nausea, vomiting, agitation, disorientation, hallucinations, psycrhythmias, ... Rarely, patients with agitation, seizures, or patients in a coma develop rhabdomyolysis and renal failure.
Phenylephrine
Symptoms: nausea, vomiting, irritability, agitation, insomnia, psychosis, convulsions, palpitations, tachycardia, increased blood pressure, reflex bradycardia.
Paracetamol
Symptoms appear after ingestion of more than 7.5 - 10 g: during the first 24 hours after ingestion - pallor skin, nausea, vomiting; anorexia, abdominal pain; increase in prothrombin time, impaired glucose metabolism. Symptoms of liver dysfunction may appear 12 to 48 hours after an overdose: increased activity of "hepatic" transaminases, hepatonecrosis. V severe cases- liver failure with progressive encephalopathy, coma. Rarely, liver failure develops with lightning speed and can be complicated by renal failure (tubular necrosis).
Treatment: gastric lavage, appointment activated carbon in the first 6 hours after an overdose, the introduction of SH-group donors and precursors of the synthesis of glutathione - methionine 8-9 hours after the overdose and acetylcysteine after 12 hours. therapeutic interventions(further administration of methionine and acetylcysteine) is determined by the concentration of paracetamol in the blood, as well as the time elapsed after taking it. Symptomatic therapy.
Release form and packaging
10 tablets are placed in a blister strip of printed aluminum foil and polyvinyl chloride film.
1 contour package with instructions for medical use in the state and Russian languages are placed in a cardboard box.
Neelam Center, B Wing, 4th Floor, Hind Cycle Road, Worley,
Mumbai - 400 030, India
This drug is on the list of symptomatic for the fight against various colds, and in cases where the subject's immunity is weakened. Rinza is one of the most affordable and effective medicinal substances... This article will cover full information about this medicine.
Rinz's lineup
Rinza lorsept has a combined form, because comes in conventional tablet or powder form. The basis of its composition will be the proportion of caffeine and paracetamol (approximately 75%). The rest is formed by substances: hydrochloride, povidone, corn starch and a slight formation of gelatin.
Rinz's tablets for colds, SARS and flu use and contraindications
The instructions for use show that Rinza should be taken by adults with a clear interval within 6 hours only 1-2 tablets, but however total amount medicines should not directly exceed the maximum daily prescribed dosage (these are 12 tablets). Children - with a period of 4 hours, only one tablet, when the maximum daily dose means - 5 tablets, the due maximum duration of the current course of treatment is 7 days (list and instructions for use for the child).
Contraindications
The doctors' comments show that this drug is quite well tolerated by all prescribed patients, it is also contraindicated for colds in the following cases:
- with prescribed individual intolerance to any one of the components of the drug;
- all patients with pronounced action atherosclerosis of the internal coronary arteries (reviews of doctors);
- all persons with arterial (external) hypertension in extreme form, as well as diabetes mellitus;
- all women during pregnancy and breastfeeding;
- any composition is contraindicated in children under 6 years of age.
Rinza instructions for use of the tablet
During the entire period of mandatory use of Rinza, it is always necessary to periodically monitor the proper functional state of the liver (method for influenza) and monitor the indicators of internal peripheral blood... Here you should know that when using of this medicine it is categorically impossible to take any anxiolytic medical remedies as well as sleeping pills. Also, when using this substance, you do not need to take third-party medications directly containing paracetamol. This is to avoid unwanted overdose.
For the current prevention of the development of hepatotoxic expression, the use of ethanol formations should be avoided for the entire period of treatment with this drug (it is also cheaper with analogues). Also, doctors' reviews show that its use affects the concentration (acuity) of attention and the speed of motor movements. Therefore, at the time of taking the drug according to the instructions, you should refrain from driving vehicles and potentially dangerous processes, which require an increased share of attention (list according to the instructions)
Rinza for children under 15 years of age, instructions for use of the pill and dosage
Experts point out that from 6 years old you need to take no more than 5 tablets per day. It all depends on the symptoms and the method of treatment. The medicine has analogues and is somewhat cheaper.
How to take Rinza tablets before or after meals?
This medicine, like similar drugs should be taken as directed, preferably before meals.
Rinza for colds during pregnancy
The drug is completely contraindicated during pregnancy, as on early dates and on last weeks third trimester. Colds during pregnancy are mainly treated traditional medicine, and if syrups and decoctions do not help, the doctor prescribes paracetamol in the minimum dosage.
Analogs
The list is as follows (all analogues are cheaper):
- Codelmixst;
- Panoxen;
- Mulsinex;
- Panoxen;
- Rinikold.
Side effects
The side effects are as follows:
- mild skin rash;
- frequent itching;
- any hives;
- slight angioedema;
- slight dizziness;
- sleep disturbance;
- increased excitability;
- increased blood pressure;
- established tachycardia;
- frequent dry mouth.
Preparation: RINZA ®
Active substance: comb. drug
ATX code: N02BE51
KFG: A drug for the symptomatic therapy of acute respiratory diseases
Reg. number: P No. 015798/01
Date of registration: 28.06.04
Owner reg. ID: UNIQUE PHARMACEUTICAL Laboratories (India)
DOSAGE FORM, COMPOSITION AND PACKAGING
?Pills round, flat, pink with dark pink and white blotches, with beveled edges and a dividing line on one side.
Excipients: colloidal silicon dioxide, crimson dye 4R, corn starch, povidone (K-30), sodium methylhydroxybenzoate, magnesium stearate, purified talc, sodium starch glycolate, purified water.
10 pieces. - blisters (1) - cardboard packs.
10 pieces. - blisters (2) - cardboard packs.
10 pieces. - blisters (10) - cardboard packs.
The description of the product is based on the officially approved instructions for use.
Pharmachologic effect:Combined agent, has antipyretic, analgesic, alpha-adrenostimulating, vasoconstrictor and antihistamine action, eliminates cold symptoms. Caffeine stimulates the psychomotor centers of the brain, enhances the effect of analgesics, eliminates drowsiness and fatigue, increases physical and mental performance, shortens the reaction time, temporarily reduces fatigue and drowsiness. Paracetamol is a non-narcotic analgesic; blocks COX, mainly in the central nervous system, affecting the centers of pain and thermoregulation; has an analgesic and antipyretic effect. Phenylephrine is an alpha-adrenergic agonist with a moderate vasoconstrictor effect. Chlorphenamine is a blocker of H1-histamine receptors. Narrows the vessels of the nose, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses; reduces exudative manifestations, suppresses the symptoms of allergic rhinitis.
Indications:
Feverish syndrome ("colds" and infectious diseases); Sinusitis, rhinorrhea ( acute rhinitis, allergic rhinitis).
Contraindications:
Hypersensitivity, severe atherosclerosis of the coronary arteries, arterial hypertension (heavy course), diabetes mellitus (severe course), pregnancy, lactation period, childhood(up to 6 years). With care. Deficiency of glucose-6-phosphate dehydrogenase; hepatic and / or renal failure, angle-closure glaucoma, prostatic hyperplasia; congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), arterial hypertension, thyrotoxicosis, diabetes mellitus, COPD (pulmonary emphysema, Chronical bronchitis), the simultaneous administration of MAO inhibitors and beta-blockers.
Side effects:
Allergic reactions (skin rash, itching, urticaria, angioedema), nausea, epigastric pain; anemia, thrombocytopenia, agranulocytosis. Increased anxiety, dizziness, increased blood pressure, sleep disturbance. Mydriasis, paresis of accommodation, increased intraocular pressure, dry mouth; retention of urine. With prolonged use in high doses - hepatotoxic effect, hemolytic or aplastic anemia, methemoglobinemia, pancytopenia; nephrotoxicity (renal colic, glucosuria, interstitial nephritis, papillary necrosis). Overdose. Symptoms: paracetamol (when taken over 10-15 g) - pallor of the skin, decreased appetite, nausea, vomiting, toxic hepatitis, up to the development of hepatonecrosis, increased activity of "hepatic" transaminases, increased prothrombin time. Treatment: symptomatic, gastric lavage, administration of SH-group donors and precursors of the synthesis of glutathione - methionine 8-9 hours after overdose and N-acetylcysteine - 12 hours later.
Method of administration and dosage:
Inside, adults - 1-2 tablets with an interval of 4-6 hours. The maximum daily dose is 12 tablets. Children over 6 years old - 1 tablet every 4 hours; the maximum daily dose is 5 tablets for no more than 7 days.
Special instructions:
During the treatment period, the parameters of peripheral blood and the functional state of the liver are monitored. During the period of treatment, hypnotics and anxiolytic drugs (tranquilizers) should not be taken. Do not take with other drugs containing paracetamol. If symptoms persist within 5 days, you should see a doctor. During the treatment period, it is necessary to refrain from using ethanol (the development of hepatotoxic effects is possible), driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.
Interaction:
Enhances the effects of MAO inhibitors, sedative drugs, ethanol. Ethanol enhances the sedative effect of antihistamine drugs. Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation. GCS increase the risk of developing glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs. Chlorphenamine simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia. Tricyclic antidepressants enhance the adrenomimetic effect of phenylephrine, the simultaneous administration of halothane increases the risk of ventricular arrhythmia. Reduces the hypotensive effect of guanethidine, which in turn enhances the alpha-adrenostimulating activity of phenylephrine.
Today, there is a wide range of medicines that help to successfully cope with the symptoms of a cold, including Rinza's drug. If you use it at the first signs of illness, you can avoid serious consequences... In any case, carefully read the instructions before taking this medication. The fact is that misuse of Rinza sometimes aggravates the patient's condition.
Rinza's action
Many people, using Rinza for colds, do not have an accurate idea of its effect on the body. Meanwhile, depending on dosage form the effect of the medication is somewhat different. Although with adequate use of any kind of this remedy the result will be positive.
Rinz's pills
Rinz's pills - combination drug which soothes most symptoms colds, namely:
- improves the functioning of the nose, restores normal breathing. This is possible thanks to phenylephrine, which has a vasoconstrictor effect and relieves swelling;
- eliminates lethargy, fatigue, drowsiness, increases efficiency and "revives" the general condition due to the content of caffeine. After all, it affects the stimulation of cardiac activity and the psychomotor of the brain, and also enhances the effect of analgesics;
- lowers the temperature, i.e. has an antipyretic effect due to paracetamol, which is part of the medication;
- reduces the severity of the headache or eliminates it altogether.
In addition, often take Rinza pills for allergic rhinitis... After all, this medication contains elements that help block the receptors that cause irritation. At the same time, lacrimation, itching and others are eliminated. discomfort.
Rinza Lorsept Pastilles
Rinza Lorsept pastilles belong to local antiseptics used in dentistry and ENT practice. They are lozenges with lemon, orange, black currant flavor and honey-lemon flavor. They are used, as a rule, as an anesthetic, anti-inflammatory and analgesic agent.
The active components of Rinza Lorsept are aimed at combating a wide range of bacteria and various fungi. Usually this drug prescribed in case of the following diseases:
- mucosal lesions oral cavity(stomatitis, gingivitis, thrush, etc.);
- infectious and inflammatory processes in the nasopharynx, throat and larynx (laryngitis, tonsillitis, pharyngitis, etc.);
- hoarseness;
- professional ENT diseases in workers of the chemical and coal industries, teachers, speakers and people of other kind of activity.
At correct use Rinza Lorsept in the patient quickly disappears pain, irritation and discomfort in the upper respiratory tract and also relieves nasal congestion.
Rinzasip powder
Rinzasip is a powder for the preparation of a medicinal solution, which is then taken internally. This form of the drug is available with different flavors: it has a lemon, orange and blackcurrant flavor.
The action of the Rinzasip drug is similar to the Rinza tablets:
- headache, muscle and joint pain decreases;
- recovers nasal breathing, edema of the nasal mucosa and paranasal sinuses decreases;
- the amount of nasal discharge is reduced;
- body temperature drops;
- general well-being improves.
Some people believe that there are also Rinz nose drops. However, this opinion is erroneous. This drug is not available as a solution for nasal administration.
Rinza's use
For many, the question of how to use Rinza is very relevant. After all, so that the drug does not cause negative impact, the dosage must be observed. But, unfortunately, in the case of colds, few people turn to specialists to clarify whether it is possible to use certain drugs to treat an ailment.
General application
In most cases, at the first symptoms of a cold, Rinza tablets are taken 4 times a day, 1-2 pieces, but their total number should not exceed 12 per day.
For children, the permitted dosage is no more than 5 tablets per day. Moreover, the time interval between doses should be at least 4 hours, and the duration of treatment with this drug should not be more than a week.
Rinza Lorsept lozenges are allowed to dissolve every 2-3 hours, but you should not use more than 8 lozenges per day. It is important to understand that given form the drug gives the best result in the initial manifestations of the disease.
It is recommended to drink Rinzasip one hour after a meal, but not more often than 4 hours and no more than 4 times during the day. The powder should be dissolved in 250ml hot water... If desired, you can also add sugar or honey to the drink. The course of therapy with Rinzasip should not exceed 5 days.
Application for sinusitis
One of the main tasks with sinusitis is to free the nasal passages from pathogenic contents and restore nasal breathing. For this, as a rule, they apply vasoconstrictor drops and sprays. However, Rinza's tablets have a similar effect, although few people use this drug for this purpose.
In the case of using Rinza for inflammation of the paranasal sinuses, it is important to understand that this medication should not be taken in conjunction with certain medications. In particular, preparations containing paracetamol or providing hypnotic effect... Moreover, when Rinza is included in the treatment regimen for sinusitis, it is advisable to control functional state liver and blood counts of the patient.
With absence clear signs improvements general condition in case of using Rinza for 5 days, it is necessary to stop taking the drug and consult a specialist. He will do required analyzes and will indicate the therapy regimen.
Contraindications
Rinza has quite a few contraindications. Mainly specific diseases... But among them, there are several main points when there is a likelihood of a negative effect of this medication on the patient's well-being:
- pregnancy and the period of breastfeeding;
- age up to 6 years, and in the case of Rinzasip - at least 15 years;
- severe forms of flow diabetes mellitus other.
But under any circumstances, it is advisable to consult a doctor before taking this medicine. After all, though Rinza helps quite effectively and in short time but caution and safety must be prioritized. Otherwise, a common cold can go not only into chronic rhinitis but also in sinusitis.
Rinza Is a combination drug that is aimed at combating the symptoms of colds and acute respiratory diseases ( ARI), including influenza. This drug contains several components at once that act on almost all symptoms of acute respiratory diseases ( ARI), which saves the patient from taking several drugs at once. Rinza contains paracetamol, caffeine, phenylephrine hydrochloride and chlorphenamine maleate. These substances are recognized as safer and more effective in clinical practice. Rinza mechanism of action
The medicinal properties of this drug are due to the presence in it of components that have antipyretic, analgesic, vasoconstrictor, antiallergic and psychostimulating effects.Paracetamol is a drug that has antipyretic and analgesic effects. Due to its properties, it reduces pain cider, namely, sore throat, headache, joint pain and muscle pain, and reduces fever. All this is associated with the inhibition of the synthesis of prostaglandins in the center of thermoregulation, which is located in the hypothalamus.
Phenylephrine hydrochloride is a vasoconstrictor. It acts on α1-adrenergic receptors, which are located on blood vessels the nasal mucosa, and leads to their narrowing. As a result, the volume of blood flowing to the nose decreases and nasal congestion is relieved. This makes nasal breathing much easier.
Chlorphenamine maleate is a remedy that has an anti-allergic effect - it eliminates itching of the eyes, nose, swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses. This is due to the fact that this substance is a histamine inhibitor ( mediator allergic reactions immediate type).
Caffeine is a drug that has a stimulating effect on the central nervous system, which ultimately leads to a decrease in sleepiness and fatigue, increasing mental and physical performance.
Is Rinza an antibiotic or not?
Antibiotics are drugs that can inhibit the growth, development and reproduction of microbes. Type antimicrobial action secrete 2 types of antibiotics - those that lead to the death of microorganisms and those that inhibit the growth and reproduction of bacteria. Also, antibiotics are divided into several groups according to their chemical structure - macrolides, aminoglycosides, tetracyclines and others.Rinza is not an antibiotic, but refers to a drug that has anti-inflammatory, analgesic and antipyretic effects as a result of inhibition of prostaglandin synthesis by inhibiting the activity of the enzyme cyclooxygenase ( COX).
What is the difference between Rinza and antiviral drugs ( remantadine, ingavirin)?
Antiviral drugs are medicines that are aimed at combating viral diseases (flu, measles, mumps and others). Today there are many antiviral drugs that can be obtained different ways... However, the process of obtaining them is rather complicated, due to which the price of these drugs may be overstated.The risk of developing arrhythmias and myocardial infarction may increase.
Barbiturates, rifampicin, tricyclic antidepressants
Drugs that have a depressing effect on the central nervous system.
In case of overdose and simultaneous reception with paracetamol, the risk of liver toxicity increases.
Corticosteroids(prednisolone, hydrocortisone)
Rinza overdose
As a rule, an overdose is due to paracetamol. If the patient has taken more than 10 g of paracetamol, then he has liver damage. Also, intake of more than 5 g can lead to liver damage, but the patient may have several risk factors - regular overuse alcohol, malnutrition, cystic fibrosis, HIV infection, long-term treatment phenobarbital, rifampicin and other drugs that stimulate liver enzymes.In case of an overdose with paracetamol, mainly adverse reactions such as anorexia ( lack of appetite), nausea, vomiting, abdominal pain, pallor of the skin, increased sweating, general malaise, jaundice, acute liver failure, hepatomegaly ( enlarged liver). The consequences of acute liver failure there may be sepsis ( blood poisoning), fungal infection, bleeding from the gastrointestinal tract, cerebral edema, coma, hypoglycemia ( a decrease in the concentration of glucose in the blood), respiratory failure, pancreatitis and others.
There are also cases in which an overdose of other components of the rhinza is not excluded.
In case of an overdose of phenylephrine, nausea, vomiting, irritability, insomnia are observed, headache, convulsions, tachycardia and increased blood pressure.
Symptoms of a caffeine overdose are abdominal pain, nausea, vomiting, chills, fever, arrhythmia, tachypnea ( rapid breathing), headache. Anxiety, insomnia, weakness, irritability, loss of appetite, tremors, hypokalemia ( a decrease in the concentration of potassium in the blood), hyponatremia ( a decrease in the concentration of sodium in the blood), hyperglycemia ( increased blood glucose concentration) and other pathological conditions.
Chlorpheniramine overdose can lead to hyperthermia ( overheating), dilated pupils, dry mouth, urinary retention, tachycardia, nausea, vomiting. Disorientation, hallucinations, psychosis, seizures and cardiac arrhythmias can also develop with an overdose of this substance.
Treatment of a suspected overdose includes gastric lavage and the appointment of activated charcoal by mouth and an antidote ( in the case of paracetamol, acetylcysteine acts as an antidote) intravenously. This treatment is effective up to 24 hours after taking paracetamol. Further treatment must be carried out in a specialized department of the hospital with the help of doctors.
Contraindications to the use of rinza
An absolute contraindication to the appointment and use of this drug is hypersensitivity to the ingredients that are included in the composition. Severe allergic reactions may occur if this medication is ingested. ). phenytoin, carbamazepine, rifampicin, isoniazid and others);
Can Rinza tablets be taken by children?
Rinza is a drug that consists of several components. This drug must be used in children strictly following the instructions for use. So, Rinza tablets can be taken by children over 15 years old. In this case, the treatment of colds and flu in children should be carried out with the help of a specialist.Can rinza be drunk if there is no fever?
The substance that has an antipyretic effect in the preparation of Rinza is paracetamol. Paracetamol provides its antipyretic effect only from a body temperature in the range from 37.8 to 38 degrees. If the patient has only mild malaise, and he does not have an increased body temperature, then in this case, it is not recommended to take this drug for prophylaxis. It should be remembered that antipyretics, like any drugs, there are side effects.Application during pregnancy and breastfeeding
Considering the fact that clinical data on the safety of the drug during pregnancy and breastfeeding are absent, the appointment of rinza is contraindicated in this category of patients. As you know, paracetamol is one of the safest non-steroidal anti-inflammatory drugs, and it does not adversely affect the health of a pregnant woman, as well as during breastfeeding. However, phenylephrine and pheniramine maleate may have bad influence on the development of the fetus and be in breast milk. V in this case it is necessary to transfer the baby to artificial feeding.Can Rinza be combined with alcohol?
This drug must not be taken at the same time as drinking alcohol in order to avoid toxic liver damage. Alcohol has a toxic load on the liver, as well as the components of the drug. Also, Rinza should not be prescribed to patients who suffer chronic alcoholism.How does Rinza affect driving?
Rinza is a drug that can make you sleepy. In this case, you must refrain from driving a car. It is also necessary to exclude engaging in activities that require high concentration, quickness of reactions and attention.Price ( price) of the Rinza preparation in the cities of Russia
The cost of drugs in pharmacies depends on the country of origin, the cost of manufacturing, transportation and storage. Also, the cost is determined by the form of release, dosage active substances and other factors. Prices of the drug in various cities of Russia
Town | Release form |
|||
Pills ( 10 pieces) | Powder for oral solution ( rinzasip with vitamin C) | Powder for solution preparation for children ( rinzasip for children, 10 sachets, 3 g each) |
||
5 sachets 5 g each | 10 sachets 5 g each |
|||
Moscow | 188 rubles | 195 rubles | 277 rubles |
|
St. Petersburg | 186 rubles | 195 rubles | 312 rubles | 249 rubles |
Novosibirsk | 150 rubles | 208 rubles | ||
Nizhny Novgorod | 209 rubles | 212 rubles | 308 rubles | 310 rubles |
Voronezh | 180 rubles | 180 rubles | 280 rubles | 265 rubles |
Samara | 200 rubles | 205 rubles | 305 rubles | |
Tyumen | 177 rubles | 286 rubles | 286 rubles |
|
Yaroslavl | 188 rubles | 190 rubles | 286 rubles |
|
Kazan | 195 rubles | 200 rubles | 300 rubles | 297 rubles |
Krasnoyarsk | 180 rubles | 280 rubles | ||
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