Calcium-D3 Nycomed Forte - official instructions for use. Calcium-D3 Orange Nycomed - official instructions for use

Funds sold in pharmacies can be roughly divided into two equal parts. The bulk - drugs with therapeutic action, the second group - helpers. They serve as prophylactic or additional means to the main treatment. It is the second group of pharmaceutical products that includes "Calcium D3 Nycomed Forte". The instructions for this tool tell about it in detail.

Why do people need calcium?

As established by scientists, about 60 basic chemical elements included in the table of D.I. Mendeleev, include organs, tissues, physiological fluids the human body. Their division is conditionally determined by two groups - micro and macro elements. The group names characterize the amount of the element's presence in the norm. Trace elements, as is clear, are contained in small doses - a maximum of a few micrograms. But macronutrients can reach a weight of several hundred grams. The presence of all the elements in the required amount contributes to the improvement of the quality of the individual's health. The lack or excess of such substances negatively affects the state of individual systems and organs.

For example, the musculoskeletal system depends on a certain amount of calcium and vitamin D3. According to physiologists, the adult human body should contain from 1 to 1.5 kilograms of this chemical element, and almost all of it is in bone tissue. Balanced diet rich in variety, natural products, allows you to replenish the required amount of all components for health. But in some cases, calcium, for example, is metabolized and consumed faster than it is replenished. It is then that calcium preparations come to the rescue. Scientists have found that calcium is absorbed in greater quantities together with Developers medicines took this moment into account and "Calcium-D3 Nycomed Forte" became the drug that allows you to obtain substances in the maximum biologically available amount.

Scary osteoporosis

The skeleton is a supporting structure; it must be strong and reliable. And the strength of bones depends on many components, in particular, on the presence in the human body of an important building material- calcium. The destruction of thin tissue, a change in density, the appearance of fragility leads to many complications, one of which is osteoporosis. This is an insidious symptom of a serious malfunction in the body. He can long time not manifest in any way.

A person lives a normal life, and meanwhile his skeleton is gradually losing its strength due to degenerative processes occurring in the bone tissue. After all, the processes of using and replenishing building material, including for bones, are ongoing. But in some situations useful material fulfill their required functions, are destroyed, metabolized, but they are not replenished. It is then that helpers should come to the rescue. Osteoporosis prophylaxis drugs replenish the necessary elements that are important for reliability skeletal system.

What does the preparation consist of?

One of the demanded pharmacy products among the helpers of the skeletal system - "Calcium D3 Nycomed Forte". The composition of the active substance is not very complicated, it is a two-component preparation, it works:

  • calcium carbonate;
  • cholecalciferol (vitamin D3).

The manufacturer of the preparation used the following form-forming components: aspartame; isomalt; monomalt; povidone; sorbitol; stearate. Lemon oil gives the preparation its taste and aroma.

In what form is the drug produced?

The drug called "Calcium D3 Nycomed Forte", used to help the bone apparatus, is manufactured by the Swiss pharmaceutical corporation Nycomed Pharma. This company has been operating for almost 150 years and today is one of the 30 largest pharmaceutical companies. The medicine with calcium and vitamin D3 is available in one dosage form- chewable tablets with lemon flavor. They are without a shell, have a biconvex rounded shape, white in color with a few blotches. The tablets may have an uneven surface, since they are not covered with a dense protective shell and have a natural structure.

How does the active substance work?

The pharmacological properties of the drug "Calcium-D3 Nycomed Forte", like any other drug, directly depend on the components working in it. This drug is based on two interacting substances - calcium and vitamin D. According to the pharmaceutical code, it belongs to pharmacological group regulators of calcium-phosphorus metabolism, and is used as a remedy for the lack of calcium and vitamin D3.

Working in combination, these components reduce the leaching of calcium from the body, and therefore increase its content in the bones. Also, calcium is an active participant in neural conduction, is responsible for muscle contractions and quality work blood coagulation systems. And vitamin D3 helps calcium to be absorbed in the intestines, thereby increasing its functional level. Together, these substances inhibit the production of parathyroid hormone (PTH), which stimulates the leaching of calcium from the bone system and the development of osteoporosis. Such a symbiosis of medicinal natural substances makes the preparation with calcium in demand in the vitamin supplement market.

Pathway of medication in the body

The instruction, which describes the main components, pharmacokinetics and pharmacodynamics, tells in detail about the drug "Calcium D3 Nycomed Forte".

Calcium entering the body through the stomach and intestines is absorbed only in about 30% of the dose taken. Since vitamin D3 helps this element to be absorbed more actively, their joint intake is more rational. Colecalciferol is absorbed up to 80% of the amount received through the gastrointestinal tract, thereby serving as a conductor for calcium, so essential for bones, teeth, ionic cell exchange. Distributed in the tissues where these components work, in the amount that is available and necessary, excess substances are metabolized in the liver and kidneys, and metabolites are excreted in the urine, feces and through the sweat glands.

When is the drug prescribed?

For the regulator of calcium metabolism - the drug "Calcium-D3 Nycomed Forte" indications for use are based on the lack of a building material for the skeletal system:

  • bone fractures;
  • prevention and treatment (in combination) of osteoporosis;
  • prevention and treatment of calcium and / or vitamin D3 deficiency.

There are quite positive reviews about the preventive properties of "Calcium-D3 Nycomed Forte", many patients consider its help in the treatment of deficient conditions effective and necessary.

In what cases should calcium not be taken?

Any medicinal or prophylactic agent has its own restrictions on use, so "Calcium-D3 Nycomed Forte" contraindications are quite extensive:

  • hypercalcemia - an increase in the amount of calcium in the blood;
  • hypercalciuria - detection of calcium in the urine;
  • hypersensitivity to drug components;
  • glucose-galactose malabsorption;
  • hereditary;
  • nephrolithiasis;
  • renal failure;
  • sarcoidosis;
  • sucrose-isomaltase deficiency;
  • tuberculosis (active form);
  • phenylketonuria.

This drug is not prescribed for use by people with limited mobility (sedentary) patients. Also, it is not recommended for children under the age of 3 years. Contraindication to the intake of "Calcium D3 Nycomed Forte" is intolerance to soybeans and peanuts.

If something is wrong

Pharmacy preparation, working to replenish the body with calcium and vitamin D3, are chewable tablets "Calcium-D3 Nycomed Forte". Side effect this remedy can manifest itself as follows:

  • pain and discomfort in a stomach;
  • hypercalcemia;
  • hypercalciuria;
  • diarrhea;
  • dyspepsia;
  • constipation (constipation);
  • hives;
  • flatulence;
  • rash;
  • nausea.

If the undesirable symptoms described above appear or if any newly identified symptoms appear, you should consult a doctor for symptomatic therapy and stop taking this remedy.

Abuse of chewable tablets with calcium can cause an overdose of active ingredients, which manifests itself as follows:

  • anorexia;
  • cardiac arrhythmia;
  • bone pain;
  • dyspepsia;
  • thirst;
  • calcification of soft tissues;
  • urolithiasis disease;
  • muscle weakness;
  • nephrocalcinosis;
  • polyuria;
  • kidney damage (organic);
  • dry mouth;
  • nausea.

Taking the drug in high dosages can provoke mental disorders.

Any manifestations of symptoms of an overdose require seeking a qualified medical help, withdrawal of the drug itself, as well as cardiac glycosides and diuretics of the thiazide group taken simultaneously with it. Loop diuretics are most often used as an antidote, such as Furosemide, bisphosphonates, oral glucocorticosteroids, and the hypocalcemic hormone Calcitonin. If there is an overdose of a drug with calcium, then it is necessary to regularly monitor such indicators of the patient's physiological state as:

  • diuresis and kidney function;
  • venous pressure (central);
  • the amount of electrolytes in the blood plasma;
  • electrical activity of the heart.

Calcium and other substances

Prescribing for use the drug for osteoporosis "Calcium-D3 Nycomed Forte", the price of which is affordable for all buyers, the doctor must take into account the medical indications medicines. Indeed, for use in the treatment of this drug and some other groups of drugs, it is very important to take into account their interaction with each other and the effect on the patient's body.

Cardiac glycosides potentiate their toxic effect when taken together with Calcium-D3 Nycomed tablets. In this case, regular monitoring of the activity of the heart is shown.

If the patient is scheduled to receive certain medications, and it can be antibiotics of the tetracycline series, bisphosphonates, levothyroxine, quinolines, sodium fluoride, together with the appointment of a drug with calcium, then the use of these funds must be separated. You can take calcium first, and after 6 hours another medicine, or first medicine, and then a medicine with calcium.

There are medications that, when taken simultaneously with Calcium D3 Nycomed Forte, reduce the bioavailability of the latter. These include glucocorticosteroids, barbiturates, laxatives, phenytoin, and cholestyramine. If such a combination is necessary for medical reasons, then it is necessary to adjust the regimen, as well as the amount of the drug with calcium.

Calcium can not only be washed out from the skeletal system, but also accumulate in tissues or blood serum. This is bad because it leads to hypercalcemia. This result can lead simultaneous reception a drug with calcium and a thiazide diuretic. If such treatment is necessary, then the patient should regularly undergo blood calcium monitoring in order to avoid the adverse consequences of an overdose of the drug.

Oxalates, found in large quantities in potatoes, rhubarb, spinach, sorrel, as well as the substance of many friable cereals - phytin provide negative impact on the absorption of calcium from gastrointestinal tract at oral administration... If the next meal included dishes from the above products, then the medicine must be taken four hours later.

How should you take the drug?

The instructions for use attached to "Calcium D3 Nycomed Forte" indicate the dosage and regimen. Since it is made as a lemon-flavored chewable tablet, it must be chewed thoroughly with meals. V preventive purposes the drug is taken in the amount of 2 tablets per day, it can be done at the same time, or by dividing the dose in half: 1 tablet in the morning and 1 in the evening. If the diagnosis of osteoporosis has already been established, then this medication is taken 3 tablets per day. The duration of treatment is determined by the attending physician with regular monitoring of the condition of bones, teeth, hair and nails and is carried out in conjunction with other medical prescriptions.

The states of calcium and vitamin D3 deficiency in the patient's body are compensated by a course intake of this medicine and take into account the patient's age.

  • up to 3 years, this medicine is contraindicated for admission;
  • from 3 to 5 years, only half or a whole tablet is prescribed per day;
  • from 5 to 12 years old, you can chew 1-2 tablets per day;
  • adults and adolescents after 12 years of age are shown one tablet twice a day.

It is not recommended to take it on its own this drug... A doctor's consultation is necessary to rule out how possible contraindications, and an overdose, and poisoning with a drug, determine the duration course treatment and the dose of the agent.

Pregnancy, lactation and calcium

Osteoporosis is serious symptom problems with the musculoskeletal system caused by the destruction of bone tissue due to insufficient amount of calcium in it. The period of gestation and breastfeeding can cause a lack of calcium in the woman's body. Many women take its signs as natural ailments of pregnant women:

  • back pain;
  • hair loss;
  • weak nails;
  • numbness of the limbs, both upper and lower;
  • destruction of tooth enamel;
  • cramps in the calf muscles.

Use "Calcium D3 Nycomed Forte" (the instruction to it offers), as a prophylactic agent necessary for pregnant and lactating mothers. But the medicine should be prescribed by a doctor, taking into account the woman's health condition and with his constant monitoring. The same applies to the lactation period. Active ingredients of this drug penetrate breast milk, and, therefore, into the child's body. Therefore, a woman needs to control the intake of this medication, as well as other ways of entering this substance into the body, since an overabundance of a chemical element can lead to pathological processes such as hypercalcemia.

The drug sold without a prescription in pharmacies - "Calcium D3 Nycomed Forte" (prices may vary somewhat) is an important component helping to maintain health. It is advisable to take it after the recommendation of your attending physician, according to the prescribed scheme. It will help make bones and teeth stronger, hair and nails healthy. For an OTC product, the average price is from 400 to 700 rubles.

Tradename drug:
Calcium-D 3 Nycomed

Dosage form
Chewable tablets (orange).

Composition for one tablet
Active ingredients: calcium carbonate - 1250 mg (equivalent to elemental calcium - 500 mg) colecalciferol (vitamin D 3) - 5 μg (200 ME) as a concentrate of colecalciferol 2 mg.
Auxiliary components: sorbitol, isomalt, povidone, magnesium stearate, aspartame, orange oil, mono- and diglycerides fatty acids.

Description:
Round, uncoated biconvex tablets white with orange scent. May have small blotches and uneven edges.

Pharmacotherapeutic group:

Calcium-phosphorus metabolism regulator.

ATX code: A12AX

pharmachologic effect
Combined drug regulating the exchange of calcium and phosphorus in the body (bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, replenishing the lack of calcium and vitamin D 3 in the body, which is necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system.

Pharmacodynamic properties
Vitamin D increases the absorption of calcium in the intestine.
The use of calcium and vitamin D 3 prevents an increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching of calcium from the bones).

Pharmacokinetic properties
Vitamin D 3 is absorbed in the small intestine. Calcium is absorbed in an ionized form in the proximal region small intestine through an active, D-vitamin dependent transport mechanism.

Indications for use

  • Prevention and treatment of calcium and / or vitamin D deficiency 3.
  • Prevention and complex therapy of osteoporosis (menopausal, senile, steroid, idiopathic, etc.). Contraindications
  • Hypercalcemia (increased concentration of calcium in the blood).
  • Hypercalciuria ( increased content calcium in urine).
  • Nephrolithiasis.
  • Vitamin D hypervitaminosis.
  • Hypersensitivity to the components of the drug.
  • Severe renal failure.
  • Active form of tuberculosis.
  • Sarcoidosis
    The drug is in dosage form - tablets are not used in children under the age of 3 years. Use with caution: pregnancy, lactation. Application during pregnancy and lactation
    Daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D 3.
    Hypercalcemia that develops against the background of an overdose during pregnancy can cause defects in mental and physical development child.
    Vitamin D and its metabolites can pass into breast milk, therefore it is necessary to take into account the intake of calcium and vitamin D from other sources in the mother and child. Method of administration and dosage
    Adults: in the treatment of osteoporosis - 1 tablet 2-3 times a day, for the prevention of osteoporosis - 1 tablet 2 times a day. With a deficiency of calcium and vitamin D:
    Adults and children over 12 years old - 1 tablet 2 times a day. Children from 5 to 12 years old: 1-2 tablets per day.
    Children from 3 to 5 years old - dosage in accordance with the doctor's recommendations. The tablets can be chewed or sucked and taken with meals. Side effect
    Allergic reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence, nausea, abdominal pain), hypercalcemia and hypercalciuria (increased calcium in the blood or urine). Overdose
    Overdose symptoms: anorexia, thirst, polyuria, decreased appetite, dizziness, fainting, weakness, nausea, vomiting, hypercalciuria, hypercalcemia, hypercreatinemia. With prolonged use of excessive doses, vascular and tissue calcification. Treatment: introduction into the body a large number fluids, the use of loop diuretics (for example, Furosemide), glucocorticosteroids, calcitonin, bisphosphonates.
    If you find signs of overdose, seek medical attention. In case of development clinical symptoms overdose, the concentration of calcium and creatinine in the blood should be determined. When increased concentration serum calcium or creatinine, the dose of the drug should be reduced or treatment should be temporarily discontinued.
    In case of hypercalciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or stop taking it. Interacting with others drugs
  • The activity of vitamin D 3 may decrease with its simultaneous use with phenytoin or barbiturates.
  • With simultaneous treatment with cardiac glycosides, ECG monitoring and clinical condition since calcium preparations can potentiate therapeutic and toxic effects cardiac glycosides.
  • Calcium and vitamin D 3 preparations can increase the absorption of tetracyclines from the gastrointestinal tract. Therefore, the time interval between taking a tetracycline drug and Calcium-D 3 Nycomed should be at least 3 hours.
  • To prevent a decrease in the absorption of bisphosphonates or sodium fluoride preparations, it is recommended to take Calcium-D 3 Nycomed no earlier than 2 hours after taking them.
  • Glucocorticosteroids reduce the absorption of calcium, therefore, treatment with glucocorticosteroids may require an increase in the dose of Calcium-D 3 Nycomed.
  • Simultaneous treatment with Kolestyramine preparations or laxatives based on mineral or vegetable oil can reduce the absorption of vitamin D 3.
  • With the simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, because they increase tubular calcium reabsorption. Furosemide and others loop diuretics on the contrary, they increase the excretion of calcium by the kidneys.
  • In patients who are simultaneously taking cardiac glycosides and / or diuretics, it is necessary to control the concentration of calcium and creatinine in the blood serum. special instructions
  • Calcium-D 3 Nycomed contains aspartame, which is converted into phenylalanine in the body. Therefore, the drug should not be taken by patients suffering from phenylketonuria.
  • To avoid overdose, it is necessary to take into account the additional intake of vitamin D 3 from other sources.
  • Consumption of foods containing oxalates (sorrel, spinach) and phytin (cereals) reduces the absorption of calcium, so you should not take Calcium-D 3 Nycomed within two hours after taking sorrel, spinach, cereals.
  • Calcium-D 3 Nycomed should be used with caution in immobilized patients with osteoporosis due to the risk of hypercalcemia. Release form
    Chewable tablets 20, 50 or 100 tablets in a polyethylene bottle high density, sealed with a screw cap, under which there is a ring for tearing off the sealing gasket, which provides control of the first opening. Part of the label is attached to the bottle with a special adhesive tape, which allows the label to be lifted. The instructions for use in the form of a folding sheet are placed under the movable part of the label. Shelf life
    3 years
    Do not use after the expiration date. Storage conditions
    Store the bottle tightly closed at a temperature not exceeding 25 ° C in a dry place. Keep out of the reach of children! Conditions of dispensing from pharmacies
    Without a doctor's prescription Manufacturer
    Nycomed Pharma AS, Norway. Manufacturer's address
    Nycomed Pharma AS
    Drammensveien 852, N-1385 Asker, Norway
    Nycomed Pharma AS
    Drammensveien 852 N-1385 Asker, Norway Representative office in Russia / CIS:
    119049 Moscow, st. Shabolovka, 10
  • Dosage Form: & nbsp

    chewable tablets (orange, mint)

    Composition:

    Chewable tablets (mint) Active ingredients:calcium carbonate - 1250 mg (equivalent to elemental calcium - 500 mg), colecalciferol (vitamin D 3) - 5.0 μg (200 IU) in the form of a concentrate of colecalciferol - 2.0 mg. Auxiliary components: sorbitol - 390 mg, mint flavor granulate *** - 31.8 mg, povidone - 36.4 mg, magnesium stearate - 6.0 mg, aspartame - 1.00 mg.

    * concentrate of colecalciferol contains, including 10% excess: colecalciferol - 0.0055 mg, alpha-tocopherol- 0.022 mg, modified corn starch - 1.607 mg, sucrose - 0.385 mg, sodium ascorbate - 0.088 mg, medium chain triglycerides - 0.066 mg, silicon dioxide - 0.026 mg.

    ** orange flavor granulate contains: isomalt -62.0 mg, orange flavor- 0.95 mg, mono- and diglycerides of fatty acids - 0.0008 mg.

    *** mint flavor granulate contains: isomalt - 31.0 mg, mint flavor - 0.80 mg, mono- and diglycerides of fatty acids

    0.0004 mg.
    Description:

    Chewable tablets (orange)

    White round biconvex tablets with orange flavor. May have small blotches yellow color and uneven edges.

    Chewable tablets (mint)White round biconvex tablets with mint flavor. May have small blotches white to grayish and uneven edges. Pharmacotherapeutic group:Calcium-phosphorus metabolism regulator Pharmacodynamics:

    Combined drug that regulates the exchange of calcium and phosphorus in the body (bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, replenishing calcium and vitamin D deficiencies 3 in the body, it is necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions, hormone production and is "a component of the blood coagulation system.

    Adequate calcium intake is especially important during growth, pregnancy and lactation.

    Vitamin D 3 increases the absorption of calcium in the intestine.

    Calcium and Vitamin D supplementation 3 prevents an increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching of calcium from the bones).

    Pharmacokinetics:

    Calcium

    Absorption: Usually the amount of calcium absorbed in the gastrointestinal tract is approximately 30% of the dose taken.

    Distribution and metabolism: 99 %, calcium in the body is concentrated in the rigid structure of bones and teeth. The remaining 1% is in intra- and extracellular fluids. About 50% of the total calcium content in the blood is in a physiologically active ionized form, of which approximately 10 % in combination with citrate, phosphate or other anions, the remaining 40 % associated with proteins, primarily albumin.

    Excretion: calcium is excreted by the intestines, kidneys and sweat glands. Renal excretion depends on glomerular filtration and tubular calcium reabsorption. VitaminD3

    Absorption: Vitamin D 3 easily absorbed into small intestine(about 80% of the dose taken).

    Distribution and metabolism: and its metabolites circulate in the blood associated with a specific globulin. converted in the liver by hydroxylation to 25-hydroxycolecalciferol. Then it is converted in the kidneys into the active form 1,25-hydroxycolecalciferol. 1,25-hydroxycolecalciferol is a metabolite responsible * for increasing calcium absorption. Unmetabolized Vitamin D 3 deposited in adipose and muscle tissue.

    Excretion: Vitamin D 3 excreted by the intestines and kidneys.

    Indications:

    - Prevention and treatment of calcium and / or vitamin D deficiency 3 .

    - Prevention and complex therapy of osteoporosis and its complications (bone fractures).

    Contraindications:

    - Hypercalcemia (increased concentration of calcium in the blood).

    - Hypercalciuria (high levels of calcium in the urine).

    - Nephrolithiasis.

    - Hypervitaminosis D.

    - Hypersensitivity to the components of the drug.

    - Hypersensitivity to soy or peanuts.

    - Severe renal failure.

    - Active tuberculosis.

    - Sarcoidosis

    The drug is in the dosage form of a tablet ne is used in children under the age of 3 years. Calcium-Dz Nycomed contains, which in the body is transformed into. Therefore, the drug should not be taken by patients with phenylketonuria.

    The drug contains isomalt and sucrose, therefore its use is not recommended for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency.

    Carefully:pregnancy, lactation, renal failure. Pregnancy and lactation:

    Calcium-Dz Nycomed is used during pregnancy to compensate for the deficiency of calcium and vitamin D in the body. The daily dose during pregnancy should not exceed 1500 mg of calcium and 600 IU of vitamin D 3 ... Overdose hypercalcemia during pregnancy can have an adverse effect on the developing fetus. Calcium-Dz Nycomed is used during lactation.

    Calcium and Vitamin D 3 can pass into breast milk, therefore, it is necessary to consider the intake of calcium and vitamin D from other sources in the mother and child.

    Method of administration and dosage:

    Calcium-Dz Nycomed is taken orally . The tablets can be chewed or sucked and taken with meals.

    Adults: in complex therapy osteoporosis - 1 tablet 2-3 times a day, for the prevention of osteoporosis - 1 pill 2 once a day.

    With a deficiency of calcium and vitamin D: Adults and children over 12 years old - 1 tablet 2 times a day.

    Children from 5 to 12 years old: 1-2 tablets per day.

    Children from 3 to 5 years old - dosage according to the doctor's recommendations.

    Special patient groups.

    Patients with impairmentFunctionsliver: No dose adjustment required. ,

    Patientswithviolation ofFunctionskidney: Do not use the drug Calcium-Dz Nycomed 'in case of severe renal failure.

    Elderly patients: The dose is the same as for adults. A possible decrease in creatinine clearance should be taken into account.

    Duration of treatment

    When used for prophylaxis and in the complex therapy of osteoporosis, the duration of treatment is determined by the doctor individually.

    When used to replenish calcium and vitamin D deficiencies 3 the average duration of the course of treatment is at least 4-6 weeks. The number of repeated courses during the year is determined individually.

    Side effects:

    Frequency side effects the drug is regarded as follows:

    Very common:> 1/10

    Frequent:> 1/100,< 1/10

    Infrequent:> 1/1000,< 1/100

    Rare:> 1/10 000,< 1/1000

    Very rare:< 1/10 000

    Violations withpartiesmetabolism and nutrition: Uncommon: hypercalcemia and hypercalciuria.

    Gastrointestinal disorders: Rarely: constipation, flatulence, nausea, abdominal pain, diarrhea, dyspepsia.

    Violations withsides of the skin and subcutaneousfiber: Very rare: itching, rash, urticaria.

    Overdose:

    Overdose symptoms (hypercalcemia): anorexia, thirst, polyuria, muscle weakness, nausea, vomiting, constipation, abdominal pain, increased fatigue, bone pain, mental disorders, nephrocalcinosis, urolithiasis and, in severe cases, cardiac arrhythmias. With prolonged use of excessive doses (over 2500 mg of calcium) - kidney damage, calcification of soft tissues.

    If signs of overdose are found, it is necessary to stop taking calcium and vitamin D, as well as thiazide diuretics and cardiac glycosides, and seek medical attention.

    Treatment: gastric lavage, fluid loss replacement, use of loop diuretics (eg, furosemide), glucocorticosteroids, calcitonin, bisphosphonates.

    It is necessary to control the content of electrolytes in blood plasma, renal function and urine output.

    In severe cases, it is necessary to measure the central venous pressure (CVP) and monitor the electrocardiogram (ECG). Interaction:

    - Hypercalcemia can potentiate the toxic effects of cardiac glycosides when used simultaneously with. calcium and vitamin D preparations. Monitoring, ECG and serum calcium levels are required.

    - Calcium preparations can reduce the absorption of tetracyclines from the (gastrointestinal tract. Therefore, tetracycline preparations should be taken at least 2 hours before or 4-6 hours after taking Calcium-Dz Nycomed.

    - To prevent a decrease in the absorption of bisphosphonate preparations, it is recommended to take them at least an hour before taking Calcium-Dz Nycomed.

    - Glucocorticosteroids reduce the absorption of calcium, therefore, treatment with glucocorticosteroids may require an increase in the dose of Calcium-Dz Nycomed:

    - With the simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, since they increase the tubular reabsorption of calcium. With the simultaneous use of thiazide diuretics, serum calcium should be regularly monitored.

    - Calcium reduces the effectiveness of levothyroxine, decreasing its absorption. The period of time between taking-levothyroxine and Calcium-Dz Nycomed should be at least 4 hours.

    - The absorption of antibiotics of the quinolone group decreases with simultaneous use with calcium preparations. Therefore, antibiotics of the quinolone group should be taken 2 hours before or after 6 hours after taking Calcium-Dz Nycomed.

    - Consumption of foodstuffs nidadt containing oxalates (sorrel, rhubarb, spinach) and phytin (cereals) reduces the absorption of calcium, so you should not take Calcium - Dz

    Special instructions:

    At long-term therapy, the calcium content should be monitored andserum creatinine. Observation is especially important in elderly patients - age with simultaneous treatment with cardiac glycosides and diuretics (see section"Interaction with other medicinal products and food") and in patients with an increased tendency to form kidney stones. In cases of hypercalcemia or signs of impaired renal function, the dose should be reduced orstop treatment.

    Vitamin D should be taken with caution in patients with renalfailure. In this case, it is necessary to control the content of calcium and phosphate in the blood serum. It is also necessary to consider the risk of soft tissue calcification.

    - To avoid overdose, - must be taken into account. additionalvitamin intake D from other sources.- Calcium and - Vitamin D 3 , should be used with caution

    immobilized patients with osteoporosis due to the risk of hypercalcemia.

    - Concomitant use with antibiotics of the tetracycline or quinolone group is usually not recommended, or should be carried out with caution (see section"Interaction with other drugs and food").

    Impact on the ability to drive vehicles Wed and fur .:

    Calcium-Dz Nycomed does not affect the ability to drive vehicles or operate technically complex mechanisms.

    Release form / dosage:Chewable tablets, 500 mg + 200 IU. Package: 20, 50 or 100 tablets in a high-density polyethylene bottle, sealed with a screw cap, iodine of which there is a ring for tearing off the sealing gasket, which provides control of the first opening.

    1 bottle together with instructions for use is placed in a carton box.

    Chewable tablets (mint), 500 mg + 200 ME.

    30 or 100 tablets per vial made of high density polyethylene, sealed with a screw cap, under which there is a ring for tearing off the sealing gasket, which provides control of the first opening.

    1 bottle together with instructions for use is placed in a carton box.

    Storage conditions:Store the bottle tightly closed at a temperature not exceeding 25 ° C. Keep out of the reach of children! Shelf life:

    3 years

    Do not use after the expiration date.

    Conditions for dispensing from pharmacies: Over the counter Registration number: P N013478 / 01 Registration date: 16.09.2011 Marketing Authorization Holder:Takeda Nycomed AS Norway Manufacturer: & nbsp Representative office: & nbspTakeda Pharmaceuticals LLC Date of information update: & nbsp 24.02.2015 Illustrated instructions

    Trade name of the drug:
    Calcium-D 3 Nycomed Forte

    Dosage form

    Composition for one tablet
    Active ingredients: calcium carbonate - 1250 mg (equivalent to elemental calcium - 500 mg) colecalciferol (vitamin D 3) - 10mkg (400 ME) in the form of colecalciferol concentrate 4 mg.
    Auxiliary components: sorbitol, isomalt, povidone, magnesium stearate, aspartame, lemon oil, mono- and diglycerides of fatty acids.

    Description:
    Round, biconvex, white, uncoated tablets with lemon aroma. May have small blotches and uneven edges.

    Pharmacotherapeutic group
    Calcium-phosphorus metabolism regulator.

    ATX code: A12AX

    Pharmacological properties
    Combined drug that regulates the exchange of calcium and phosphorus in the body (bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, replenishing the lack of calcium and vitamin D 3 in the body, which is necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system.
    Vitamin D increases the absorption of calcium in the intestine.
    The use of calcium and vitamin D 3 prevents an increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching of calcium from the bones).
    Vitamin D 3 is absorbed in the small intestine. Calcium is absorbed in ionized form in the proximal small intestine through an active, D-vitamin dependent transport mechanism

    Indications for use

  • For the prevention and complex therapy of osteoporosis and its complications (bone fractures).
  • To replenish the deficiency of calcium and / or vitamin D 3. Contraindications
  • Hypercalcemia (increased concentration of calcium in the blood).
  • Hypercalciuria (high levels of calcium in the urine).
  • Nephrolithiasis.
  • Vitamin D hypervitaminosis.
  • Hypersensitivity to the components of the drug.
  • Severe renal failure.
  • Active tuberculosis.
  • Sarcoidosis
    The drug in the dosage form of a tablet is not used in children under the age of 3 years. Use with caution: pregnancy, lactation. Application during pregnancy and lactation
    The daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D 3. Hypercalcemia that develops against the background of an overdose during pregnancy can cause defects in the mental and physical development of the child. Vitamin D and its metabolites can pass into breast milk, therefore it is necessary to take into account the intake of calcium and vitamin D from other sources in the mother and child. Method of administration and dosage
    Adults: for the prevention of osteoporosis - 1 tablet 2 times a day; in the complex therapy of osteoporosis - 1 tablet 2-3 times a day. To replenish calcium and vitamin D deficiencies:
  • Adults and children over 12 years old - 2 tablets per day.
  • Children from 3 to 12 years old - 1 tablet a day or as directed by a doctor.
    The tablets can be chewed or sucked and taken with meals. Side effect
    Allergic reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence, nausea, abdominal pain), hypercalcemia and hypercalciuria (high levels of calcium in the blood or urine). Overdose
    Overdose symptoms: anorexia, thirst, polyuria, loss of appetite, dizziness, fainting, weakness, nausea, vomiting, hypercalciuria, hypercalcemia, hypercreatinemia. With prolonged use of excessive doses, vascular and tissue calcification.
    Treatment: the introduction of a large amount of fluid into the body, the use of loop diuretics (for example, Furosemide), glucocorticosteroids, calcitonin, bisphosphonates.
    If you find signs of an overdose, seek help.
    If clinical symptoms of an overdose develop, the concentration of calcium and creatinine in the blood should be determined. In the case of an increased concentration of calcium or creatinine in the blood serum, the dose of the drug should be reduced or the treatment should be temporarily discontinued.
    In case of hypercalciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or stop taking it. Interaction with other medicinal products
  • The activity of vitamin D 3 may decrease with its simultaneous use with phenytoin or barbiturates.
  • With simultaneous treatment with cardiac glycosides, it is necessary to monitor the ECG and the clinical state, because calcium preparations can potentiate the therapeutic and toxic effects of cardiac glycosides.
  • Calcium and vitamin D 3 preparations can increase the absorption of tetracyclines from the gastrointestinal tract. Therefore, the time interval between taking a tetracycline drug and Calcium-D 3 Nycomed Forte should be at least 3 hours.
  • To prevent a decrease in the absorption of bisphosphonates or sodium fluoride preparations, it is recommended to take Calcium-D 3 Nycomed Forte no earlier than 2 hours after taking them.
  • Glucocorticosteroids reduce the absorption of calcium, therefore, treatment with glucocorticosteroids may require an increase in the dose of Calcium-D 3 Nycomed Forte.
  • Simultaneous treatment with cholestyramine preparations or laxatives based on mineral or vegetable oil can reduce the absorption of vitamin D 3.
  • With the simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, because they increase tubular calcium reabsorption. Furosemide and other loop diuretics, on the other hand, increase renal excretion of calcium.
  • In patients who are simultaneously taking cardiac glycosides and / or diuretics, it is necessary to control the concentration of calcium and creatinine in the blood serum. special instructions
  • Calcium-D 3 Nycomed Forte contains aspartame, which is converted into phenylalanine in the body. Therefore, the drug should not be taken by patients suffering from phenylketonuria.
  • To avoid overdose, it is necessary to take into account the additional intake of vitamin D 3 from other sources.
  • Consumption of foods containing oxalates (sorrel, spinach) and phytin (cereals) reduces the absorption of calcium, so you should not take Calcium-D 3 Nycomed Forte within two hours after taking sorrel, spinach, cereals.
  • Calcium-D 3 Nycomed Forte should be used with caution in immobilized patients with osteoporosis due to the risk of hypercalcemia. Release form
    Chewable tablets (lemon).
    30, 60 or 120 tablets per vial made of high density polyethylene, sealed with a screw cap, under which there is a ring for tearing off the sealing gasket, which provides control of the first opening. Part of the label is attached to the bottle with a special adhesive tape, which allows the label to be lifted. The instructions for use in the form of a folding sheet are placed under the movable part of the label. Shelf life
    3 years
    Do not use after the expiration date. Storage conditions
    Store the bottle tightly closed at a temperature not exceeding 25 ° C in a dry place.
    Keep out of the reach of children! Conditions of dispensing from pharmacies
    Without a doctor's prescription. Manufacturer
    Nycomed Pharma AS, Norway. Manufacturer's address
    Nycomed Pharma AS
    Drammensveien 852, N-1385 Asker, Norway
    Nycomed Pharma AS
    Drammensveien 852 N-1385 Asker, Norway Representative office in Russia / CIS:
    119049 Moscow, st. Shabolovka, 10
  • The popular medicine "Calcium D3 Nycomed" is based on substances such as calcium and vitamin D3. The main pharmacological action This medication is that it prevents excessive synthesis of the parathyroid hormone, which improves bone resorption. Both active substances the drug contribute to the regulation of phosphorus-calcium metabolism in the patient's body. Good feedback this medication has earned, among other things, for its relatively low cost. However, many people probably still would like to know if there is an analogue of "Calcium D3 Nycomed" cheaper in cost. Of course, there are such drugs on the modern pharmacological market.

    Why do they take

    Vitamins "Nycomed calcium d3 Nycomed"drink first of all for that, to:

      make up for the lack of calcium in the bones;

      improve blood clotting;

      restore bone tissue;

      mineralize teeth and bones;

      regulate the absorption of calcium in the gastrointestinal tract.

    This medicine is supplied to the market in the form of chewable round tablets in jars. Its dosage depends on the age of the person and the type of disease. Usually, patients are prescribed 2-3 tablets per day. The course of treatment usually lasts 1-2 months. Choosing an analogue "Calcium D3 Nycomed" is cheaper, you should pay attention, of course, to its instructions for use. Some drugs in this group are prescribed in lower dosages, others in higher dosages.

    There is "Calcium D3 Nycomed" about 200-250 rubles. for 30 tablets.

    Contraindications

    Of course, "Calcium D3 Nycomed" and cheaper analogs of this medication can not be prescribed to patients by doctors in all cases. Contraindications to the use of the original medicine are:

      renal failure;

      high blood calcium;

      acute form of tuberculosis;

      sarcoidosis;

      isomalt sugar deficiency;

      phenylketonuria.

    Of course, you cannot take this medication if you are intolerant of any of its components.

    The best cheap counterparts

    Judging by the reviews, this drug is quite effective. But since it is quite expensive, of course, many consumers are also interested in what to replace "Calcium D3 Nycomed". Cheap counterpart instead of this drug, for example, you can use the following:

      Complivit calcium D3.

      Calcid.

      "Calcium asset".

      "Beresh calcium D3".

      Kalcemin.

    Also on sale there is an analogue "Calcium D3 Nycomed" cheaper in cost under the name "Mountain calcium with D3 and mummy".

    Analog - "Complivit"

    Like "D3 Nycomed", this drug is very popular on the market. It is also intended to regulate the calcium-phosphorus balance in the body. The difference between these two drugs is that Complivit D3 additionally contains lemon acid... This component is believed to contribute to better calcium absorption.

    Cost "Complivit calcium D3" is much cheaper than "D3 Nycomed". For 30 tablets of this medicine in a pharmacy they usually ask for 100-120 rubles. In this case, the daily dosage of this drug is most often 1-2 tablets.

    Reviews

    This medicine is most often used instead of Calcium D3 Nycomed. What are the high-quality and inexpensive analogues for this medication? In answer to this question, in most cases, this particular drug is called. Consumers have a generally good opinion of this dietary supplement. Patients refer to the unconditional advantages of this medication, first of all, that it simply perfectly replenishes the lack of calcium in the body. Also, many patients note the fact that this medication just perfectly promotes bone healing after fractures. There are different reviews regarding the taste of Complivit Calcium D3 tablets. Many patients find this medicine to be drunk very easily. Others believe that the taste of these pills is not particularly pleasant.

    The disadvantage of this drug, some patients consider only the fact that sometimes people have its individual intolerance. It is better not to take "Complivit calcium D3" to such patients. This can negatively affect the health of their liver.

    Medicine "Calcid": composition and cost

    This analogue is also often prescribed by doctors instead of "Calcium D3 Nycomed". The main advantage of this drug is its low cost. This medicine replenishes calcium in the body quite well. Vitamin D3, which improves the absorption of this microelement, is present in the preparation, despite its absence in the name. In fact, "Calcid" is just a cheap domestic generic version of the drug "D3 Nycomed". The drug "Calcid" costs about 150 rubles. for 100 tab. He is prescribed in the amount of about 3 tablets per day.

    Consumer opinion about "Calcide"

    This drug is chosen by many consumers looking for cheaper analogs for Calcium D3 Nycomed. This medication has earned excellent reviews of patients. Most patients note the fact that it helps no worse than the advertised "Calcium D3 Nycomed". Of course, this medicine has earned excellent reviews for its very low cost.

    To the disadvantages of "Calcid" consumers refer only to the fact that the sale sometimes comes across defective (too hard) tablets.

    "Calcium asset"

    Many drugs in this group, including, for example, "Calcid", are not recommended for women who are expecting a baby. Therefore, many consumers are interested in whether there are analogues for "Calcium D3 Nycomed" on the market that are cheaper for pregnant women. Fortunately, such medicines exist in pharmacies today. For example, a pleasant exception in in this case is "Calcium asset". This drug is called the best in the group for pregnant women.

    In addition to the main substance itself, the composition of this medication includes a complexone substance, which stabilizes the work of "building-destruction" of human bone tissue. This medicine is made on the basis of not ordinary, but vegetable calcium obtained from the amaranth plant. In this form, this trace element is much better absorbed by the human body.

    This analogue "Calcium D3 Nycomed" is cheaper than the latter. The price for it in pharmacies is about 80 rubles. for 40 tab.

    Reviews of the medication

    This dietary supplement is also praised by many consumers. However, some people who took it, believe that the effectiveness of the drug "Calcium D3 Nycomed" is somewhat inferior. This medicine is cheaper than some other analogues. But it is recommended to take it not 2-3 tablets a day, but 4. The effect, according to many consumers, when using this medication is noticeable later than when using Calcium D3 Nycomed.

    Among the disadvantages of this medication, among other things, some consumers also refer to the fact that it can negatively affect the functioning of the kidneys.

    "Beresh calcium D3"

    This drug can also be attributed to fairly effective cheap substitutes "Nycomed D3". It costs about the same - in the region of 200-250 rubles. for 30 tablets. This dietary supplement is produced in Hungary. Indications and contraindications for him are the same as for the drug "Calcium D3 Nycomed".

    Loading ...Loading ...