Furosemide is a strong diuretic (saluretic) agent, effective when administered orally and parenterally. The diuretic effect is due to inhibition of the reabsorption of sodium and chlorine ions in the kidneys. The drug is equally effective for acidosis and alkalosis.
The action of furosemide is rapid: the diuretic effect when administered intravenously develops within a few minutes, when taken orally - within the first hour. The duration of the effect after a single intravenous administration is 1.5-3 hours, after oral administration - more than 4 hours. These properties make possible use furosemide in emergency cases - with pulmonary and cerebral edema. The maximum severity of the diuretic effect is observed during the first 2 days. In a number of situations, furosemide has diuretic effect with insufficient effectiveness of other diuretics.
Indications for use of the drug Furosemide
Stagnation in small and big circle blood circulation caused by heart failure, liver cirrhosis with symptoms of portal hypertension, pulmonary and cerebral edema, barbiturate poisoning, eclampsia, hypertonic disease, including for the relief of hypertensive crises. The drug can be used in combination with other antihypertensive drugs.
Use of the drug Furosemide
Orally before meals, intravenously and intramuscularly. Orally, 0.04 g is usually prescribed once a day (in the morning). If the effect is insufficient, the dose is increased to 0.08-0.16 g/day in 2-3 doses with an interval of 6 hours. After swelling decreases, lower doses are prescribed with a break of 1-2 days.
For hypertension (arterial hypertension), furosemide is prescribed 0.02-0.04 g once a day. With concomitant heart failure, the daily dose can be increased to 0.08 g. When taken with other antihypertensive drugs the dose of furosemide is usually 0.02 g 1-2 times a day.
In case of impaired absorption in the intestine, loss of consciousness, or if it is necessary to obtain a quick effect, furosemide is administered intramuscularly and intravenously (slowly in a stream). Daily dose for parenteral administration- 20-60 ml (1-2 times a day). After achieving the desired effect, proceed to oral administration of furosemide.
Contraindications to the use of the drug Furosemide
First half of pregnancy, hypokalemia, hepatic coma, terminal stage renal failure, mechanical obstruction of the urinary tract.
Side effects of the drug Furosemide
Nausea, diarrhea, hyperemia and itching of the skin, arterial hypotension, reversible decrease in hearing acuity, interstitial nephritis. Due to increased diuresis, dizziness, depression, muscle weakness, thirst, hypokalemia, hyperuricemia, uricosuria, and hyperglycemia may occur. During development side effects the dose of furosemide should be reduced or discontinued.
Drug interactions Furosemide
List of pharmacies where you can buy Furosemide:
- Saint Petersburg
The drug that affects kidney function is Furosemide. What is it prescribed for and how is it used? This medicine belong to the group of diuretics. It removes substances such as sodium, potassium, magnesium, calcium from the human body well and lowers blood pressure. Active ingredient the drug promotes excretion and has a hypotensive effect on the patient.
Action of the drug and release form
The effect of using the medication occurs very quickly and lasts a short period of time. When the drug is administered intravenously, it healing effect occurs within 5-10 minutes. If you use the drug in tablet form, its effect begins in about an hour, and maximum effect observed after 1.5-2 hours. Today, Furosemide can be produced in three forms: tablets (40 mg), injection solution (2 ml), granules for preparing a solution that is taken orally.
"Furosemide": what is it prescribed for?
This drug is prescribed to patients for therapy that may occur with:
- chronic and renal failure;
- acute heart failure;
- arterial hypertension;
- cerebral edema;
- burns;
- hypertensive crisis.
The medication should be used only as prescribed by the attending physician to avoid possible complications.
Use of the drug "Furosemide"
It is recommended to take in the morning before breakfast. Adults are usually prescribed a dosage of 40 mg once daily. The doctor may increase the amount of the drug to 160 mg if necessary. If the swelling decreases, then the dose of the medicine is reduced with a break of several days. The maximum allowable amount of the drug per day is 1500 mg. How to take Furosemide for children: the dose of the medication should be 3 mg per 1 kg of the child’s weight, this amount can be taken in several doses. But at the same time, the maximum daily amount of medication for a child should not exceed 40 mg. After swelling has reduced, the drug can be taken only a few times a week. More details about how to take Furosemide can be found in the instructions, as well as from your doctor.
Contraindications and side effects
People with hypersensitivity to the components of the drug are not recommended to take Furosemide. We have already figured out what this drug is prescribed for, let’s see who should not take this medication. It is prohibited for people with kidney and liver failure, obstruction urinary tract, anuria, diabetes mellitus. These are not all contraindications to the use of the drug Furosemide. It is not prescribed to children under three years of age. Also, the medicine should not be taken for pancreatitis or severe hypotension. Among the side effects, of which there are many, we can note itchy skin, nausea, vomiting, dizziness, thirst, depression, hyperglycemia. The medicine should not be used for treatment in the first half of pregnancy.
Helpful information
This article is not an instruction for the use of the drug Furosemide. For what it is prescribed and how it is used, you can find out in more detail from the instructions for the drug or by consulting with your doctor. It should be noted that under no circumstances should you take this remedy on your own - this can lead to an overdose and worsening the patient’s condition. When using the drug, the level of urea, electrolytes and carbonates should be monitored.
Furosemide, what do these tablets help with? The drug is well known for its diuretic properties, which help relieve swelling. The diuretic "Furosemide" instructions for use prescribes taking it for edema, heart failure, hypertension.
Composition and release form
The medication is produced in the form of tablets for internal use, as well as a solution for injection. The active element of the drug "Furosemide", which helps with edema, is the substance of the same name. Diuretic tablets include 0.04 g active substance, injections contain 10 mg/ml.
Injections are supplied in 2 ml ampoules. Better absorption The medication is supported by auxiliary components, the list of which depends on the form of release: starch, silicon dioxide, sodium hydroxide, magnesium stearate, sodium chloride, povidone and other components.
Pharmacological properties
Diuretic tablets "Furosemide", which helps the medicine for kidney diseases, intensively remove water and magnesium and calcium ions from the body. Thus, the diuretic effect of the active element is manifested. When using the drug for heart failure, the load on the myocardium is reduced.
This occurs as a result of dilation of arteries and veins. The effect of the drug is observed after 5 minutes with intravenous injection and after an hour when using tablets. Therapeutic effect lasts for 2-3 hours. If kidney function deteriorates, the medication acts for 6-8 hours.
Medicine "Furosemide": what helps
The medication is prescribed for various types of edematous syndrome. Indications for the use of the drug "Furosemide" include the following diseases and conditions: 
heart asthma; excess calcium in the body; pulmonary edema; hypertensive crisis; heart failure; eclampsia; cerebral edema; complicated arterial hypertension; nephrotic syndrome; cirrhosis of the liver.
The drug is also used when performing forced diuresis.
What does Furosemide in ampoules help with?
The instructions explain that the indications for use injection form similar to tablets. However, the injections work faster. Doctors, when asked: “What is the Furasemide solution intended for?”, answer that intravenous administration can quickly reduce pressure and preload on the myocardium. This plays an important role when emergency conditions sick.
Contraindications
The instructions for use prohibit the use of the drug "Furosemide" for:
hypersensitivity to the active element; stenosis urethra; arterial hypotension; digitalis intoxication; pancreatitis; acute glomerulonephritis; hypokalemia; diabetic coma; increased venous pressure; acute failure kidney; hepatic coma; gout; cardiomyopathy; urinary duct stones; liver failure in a complex form; hyperglycemic coma; hyperuricemia; aortic stenosis; alkalosis; precomatose states; acute myocardial infarction.
Caution when using the product should be observed by elderly people, with diabetes mellitus, prostate hyperplasia, hypoproteinemia, and atherosclerosis. The drug "Furosemide" during pregnancy and breastfeeding can only be used as a means emergency care under the supervision of a doctor.
Medicine "Furosemide": instructions for use 
The treatment regimen is determined by a specialist depending on clinical picture pathology. Tablets are taken in a volume of 20 to 80 mg per day. The dosage can be gradually increased to daily use means up to 0.6 g. The amount of Furosemide for children is calculated based on body weight 1-2 mg per kg, not more than 6 mg per kg.
Instructions for the use of Furosemide injections
Volume of intramuscular or intravenous injections should not be higher than 0.04 g per day. It is possible to double the dose. Doctors recommend injecting the drug into a vein infectiously within 2 minutes. Injections into muscle tissue are only possible if it is impossible to use tablets and intravenous injections.
At acute conditions Injections into the muscle are contraindicated.
Drug interactions
The combined use of Furosemide and other drugs may cause negative reactions body. The combination of the medication with hypoglycemic drugs, cephalosporins, aminoglycosides, indomethacin, NSAIDs, and insulin is unacceptable. Do not take the product together with digitoxin, astemizole, digoxin, ACE inhibitors, cisplatin, cholestyramine, cisapride, phenytoin, colestipol, lithium carbonate.
Side effects
The drug "Furosemide", reviews and instructions confirm this, can cause negative reactions in the body. Side effects include:
tachycardia, dizziness, hearing impairment; anorexia, oliguria, exfoliative dermatitis; aplastic anemia, dehydration, thrombophlebitis; orthostatic hypotension, muscle weakness; blurred vision, dry mouth; interstitial nephritis, urticaria; thrombocytopenia, metabolic acidosis; kidney calcification (in newborns); arrhythmia, headache, cholestatic jaundice; hematuria, skin itching, hypochloremia; low blood pressure, tetany, stool disorders; urinary retention, purpura, leukopenia; hyponatremia, collapse, apathy; nausea or vomiting, lethargy, impotence; necrotizing angiitis, agranulocytosis; hypovolemia, confusion; exacerbation of pancreatitis, vasculitis; anaphylactic shock, adynamia, drowsiness, erythema.
Price and analogues
"Furasemide" can be replaced the following drugs– analogues: “Lasix”, “Torasemide”, “Trigrim”, “Furosemide Sopharma”. You can buy Furosemide tablets for 16–20 rubles, the price of injections is 25 rubles.
Opinions of patients and doctors
The drug "Furosemide", reviews from experts confirm this fact, is a key remedy for the treatment of edema syndrome in people with heart failure. This fast-acting drug. Patients say that in addition to helping with edema and hypertension, the medication has side effects and is addictive (it is not advisable to use long time).
Many women use the drug Furosemide for weight loss. This product allows you to quickly get rid of 3 - 5 kg excess weight. However, doctors do not recommend taking the drug for weight loss, since it does not break down excess fat, and removes water and others necessary substances. Women claim that when taking more than 2 capsules per week, side effects and addiction appear.
On the forums you can come across the question: Which is better - Lasix or Furosemide? Pharmacists explain that the drugs are identical, and their choice depends on price and availability.
Congestion, swelling of soft tissues are quite common disorders that occur in many diseases different systems organs. You can improve the outflow and exit of fluid from the body with the help of medications, of which there are a huge variety today. And quite often doctors recommend the drug Furosemide to their patients. What does it help with? What properties does it have? Are there any contraindications to treatment? Are side effects possible? The answers to these questions are of interest to every patient.
Composition and release form of the drug
The diuretic "Furosemide" is available in the form of tablets, as well as a solution for intravenous or intramuscular administration. There are also granules for preparing a suspension - this form of medicine is more suitable for treating children.
The main active substance of the drug is furosemide. One tablet contains 40 mg of this component. You can buy packs of 20 or 50 tablets at the pharmacy. In some cases (especially when it comes to severe edema), it is advisable to use an injection solution - it is sold in 2 ml glass ampoules with a furosemide concentration of 1%. Today, packages of 10, 25 and 50 ampoules are sold.
In fact, in almost every pharmacy you can easily purchase the drug Furosemide. Doctor's prescription for tablets in this case not needed, although some pharmacies have sales restrictions.
Basic pharmacological properties
IN modern medicine The drug Furosemide is very often used. Its use in some cases is simply necessary. This is a fast-acting diuretic that inhibits the processes of reabsorption of chlorine and sodium ions in the proximal and distal tubules of the kidney, which accelerates the process of excretion of fluid from the body. The drug has no effect on glomerular filtration, therefore it is prescribed even in the presence of renal failure. Furosemide also expands peripheral vessels, which ensures a reduction blood pressure.
After taking the pill, the effect usually begins to appear within 30-50 minutes. If we are talking about intravenous administration, then the increase in the volume of urine excreted begins after 15-20 minutes. The effect of the medicine lasts about 3-4 hours.
The drug "Furosemide": what is it taken for? Indications for therapy
Every person experiences poor health from time to time. So in what cases is it advisable to take the drug "Furosemide"? What does it help with? The main indication for use is edema syndrome. In turn, edema can be a symptom of a variety of diseases.
Of course, fluid stagnation often indicates the presence of kidney problems. In such cases, doctors often prescribe Furosemide. Indications for use: edema caused by chronic renal failure, nephrotic syndrome, hypercalcemia. In addition, the drug helps with hypertension, chronic heart failure, eclampsia, and cardiac asthma. The medicine also helps fight swelling, which is associated with liver disease. Indications also include pulmonary and cerebral edema.
Medicine "Furosemide": instructions
These tablets, as mentioned earlier, can be freely purchased at the pharmacy. If you have any problems, however, you should first consult a doctor. Only a specialist can prescribe you to take the drug Furosemide. How to take pills, what is the maximum daily dose how long the treatment will last - you will find the answers to all these questions from your doctor. The instructions for use contain only general recommendations.
As a rule, the initial dose of the drug for adults is 40 mg of furosemide (one tablet). If no changes occur after taking the medication, the doctor may increase the dose by 80-120 mg every 6-8 hours until a normal diuretic effect appears. However, there are some limitations. You can take no more than four tablets (160 mg) at a time. The maximum daily dose is 300 mg, but in such quantities the medicine cannot be used for maintenance therapy, only as an emergency measure.
Often patients suffering from swelling and arterial hypertension, the drug Furosemide is prescribed. How to take it in such cases? Most often, doctors recommend taking one tablet twice a day. The duration of therapy is determined individually. As soon as the swelling begins to disappear, the dose of the medication is gradually reduced.
Intravenous and intramuscular injection It is advisable only for persistent swelling, as well as in cases where oral administration impossible. When it comes to treating children, the daily dose is 1-2 mg of furosemide per kilogram of weight.
Doctors often prescribe the drug Furosemide (tablets) to their patients. Instructions for use contain some special recommendations. Against the background of a long course of medication, it is very important to constantly monitor blood pressure, as well as monitor the concentration of electrolytes in the plasma. Some patients are also advised to take potassium supplements and eat a diet rich in this and other minerals.
Are there any contraindications?
Many people are interested in the question of whether all categories of patients are allowed to take the drug Furosemide (tablets). The instructions for use confirm that there are some contraindications in this case. Every patient should familiarize themselves with their list before starting therapy.
To begin with, it is worth saying that the drug is not prescribed to a patient with hypokalemia, since the tablets can further reduce the level of potassium in the blood, which will affect the functioning of the entire body, especially of cardio-vascular system. Contraindications also include increased sensitivity to any of the components of the drug, lactose intolerance, lactase deficiency and wheat allergy.
The drug should not be prescribed in the presence of severe renal or liver failure, hepatic coma. Contraindications also include acute glomerulonephritis, in which there is a violation of the outflow of urine. The drug should not be taken by patients with water-electrolyte imbalance, decompensated aortic and mitral stenosis, increased venous pressure, hypertrophic obstructive cardiomyopathy. The tablets are not intended for use in children under three years of age.
Many people need to take the drug Furosemide. Indications for therapy are most often swelling, and it is no secret that many pregnant women face a similar problem. It is immediately worth noting that taking this medication in the first trimester is strictly prohibited. In the second half of pregnancy, therapy is possible, but only under the supervision of a doctor. By the way, during lactation the medicine affects the functioning of the mammary glands, causing a decrease in the amount of milk (due to the removal of fluid). If therapy is still necessary, then during treatment breast-feeding It's better to stop.
Main side effects
Many people are interested in questions about what the drug “Furosemide” is, what it is used for, etc. But an equally important aspect is the presence of side effects. Statistical studies have shown that complications in most cases are the result of improper or excessive long-term use medicines. If you follow all the doctor's recommendations, the likelihood of developing side effects is minimal.
Hypotension and interstitial nephritis may develop during therapy. It is also possible that blood potassium levels may decrease, glucose levels may increase, and uric acid, which is associated with increased diuresis. Sometimes there are reactions from the digestive system (nausea, vomiting) and nervous systems(dizziness, headaches, fatigue, depression, confusion). It is also possible that extreme thirst, dry mucous membranes. Some patients develop skin allergic reactions.
Interaction with other drugs
The diuretic Furosemide is not recommended to be taken together with cephalosporins, ethacrynic acid, amphotericins and other drugs that have a nephrotoxic effect. This drug also increases the activity of theophylline and diazoxide, reduces the effect of allopurinol, non-depolarizing muscle relaxants. Be sure to tell your doctor about all medications you take. During therapy it is strictly forbidden to drink alcohol.
Overdose and its consequences
Today, many patients are faced with the need to take the drug Furosemide. Indications for its use are swelling and fluid stagnation, which, unfortunately, some people encounter very often. Unfortunately, too large doses of this medicine can lead to dangerous consequences, in particular, hypovolemia - a condition that is accompanied by a decrease in circulating blood volume. Against the background of such a disorder, it is possible a sharp decline blood pressure, as well as orthostatic collapse. After an overdose, the patient must be taken to the hospital immediately. First of all, he needs to be given an electrolyte solution in order to restore blood volume. If necessary, further symptomatic therapy is carried out.
How much does the medicine cost?
So, we found out what the instructions say about the drug Furosemide. The tablets, their composition and properties are certainly very interesting. But not less important factor For many, the price of the medicine is also a factor.
So how much will the drug cost? In fact, Furosemide stands out among other diuretics not only because of its high efficiency, but also because of its affordable cost. A package of 50 tablets with a dose of the active substance of 40 mg costs about 30-40 rubles. But 10 ampoules of this medicine will cost 25-30 rubles, which, you see, is not so much. Of course, the figure may vary depending on the patient’s city of residence, the pharmacy whose services he decided to use, and many other factors.
Analogues of the drug
In some cases, for a number of reasons, patients are not suitable for a particular medicine. Therefore, many are interested in whether it is possible to replace Furosemide with something. Analogues of this drug, of course, exist. Modern pharmaceutical market offers a huge selection of diuretics.
For example, Lasix is considered a fairly good substitute. The doctor may also recommend taking medications such as Furon or Frusemide. These are structural analogues that contain the same active substance and, accordingly, have a similar effect.
There are other diuretics that contain different components, but provide the same effect. Doctors often prescribe medications to their patients such as “Urea”, “Mannitol”, “Trifas”, “Clopamide”, “Uregit”. It's pretty strong drugs, which help quickly solve the problem with swelling. There are means of a milder effect, the list of which includes “Cyclomethiazide”, “Hypothiazide”, “Pterofen”, “Diacarb”, “Veroshpiron”.
In any case, you should understand that you cannot independently look for a substitute for the drug Furosemide. Only the attending physician can select analogues, since everything here depends on the patient’s health status, his age, the characteristics of the disease and individual needs. Uncontrolled reception diuretics can lead to dangerous consequences.
The drug Furosemide is effective diuretic fast action, used for excessive accumulation of fluid in the organs of the urinary system, as a diuretic for edema, etc. Let's take a closer look at the drug Furosemide - what it is prescribed for, how the tablets or solution work and how effective they are.
Characteristics of the product
The drug is available both in the form of tablets and in the form of a solution for injection. The speed at which the first positive results of treatment with Furosemide appear depends on the use of one or another dosage form drug. So, when administered intravenously, it can quickly cause the desired effect and has a diuretic effect after 15 minutes, when using the tablet form - after half an hour. The effect lasts for quite a long time, up to four hours.
For Furosemide, the indications for use are quite extensive. This medicine is prescribed for diseases such as hypertension, renal and heart failure, nephrotic syndrome, as well as serious violations liver function (for example, with cirrhosis).
Furosemide is also often chosen for cystitis. Unlike many drugs of similar action, it does not reduce glomerular filtration. This allows it to be used in cases of renal failure. The hypotensive effect of the drug expands the scope of its application.
However, this drug may not always be prescribed. Contraindications for Furosemide may include:
The drug must be prescribed by a doctor who first explains how to take Furosemide correctly and how to respond to possible side effects. If symptoms such as nausea, vomiting, attacks of thirst, dizziness, or diarrhea occur, you should immediately inform your doctor. Usually in this case the dosage of the drug is reduced, or Furosemide is replaced with another drug. In addition to those listed, side effects such as various allergic reactions may occur, general weakness and etc.
As a rule, Furosemide for edema is prescribed in a dosage of 40 mg per day, for which the method of administration is determined - 1 tablet per day in the morning. The dosage can be doubled and divided into two doses with an interval of 6 hours (for the first half of the day). After the swelling decreases, the dosage of the drug is gradually reduced, the interval between applications increases. For children, the dosage is calculated depending on body weight, namely 1-2 mg of medication per kilogram of weight.
Use of Furosemide for cystitis
In order to understand why Furosemide is prescribed for cystitis, you need to know what this disease is. Cystitis is inflammatory process, flowing in bladder, which is bacterial in nature and primarily affects the mucous membrane of the organ. The causative agents of cystitis are Escherichia coli and Pseudomonas aeruginosa bacteria, staphylococcus and Candida fungi. Once in the bladder, these microorganisms begin to actively multiply, resulting in disruption of the functioning of this organ.
Cystitis, as an indication for the use of Furosemide, is considered because the inflammatory process occurring in the bladder requires the prevention of stagnation of urine, as a condition for its development. Unfortunately, most often cystitis develops into chronic form due to the patient's incorrect approach to treatment. Often the patient independently chooses medications and methods of therapy, uses means traditional medicine, determines when to stop treatment. In this case, little attention is usually paid to establishing the process of excreting urine in a sufficient volume, and this has a direct impact on suppressing the source of inflammation in the organs of the urinary system in general and the bladder in particular.
Typically, during the treatment of cystitis, doctors recommend that patients drink as much fluid as possible, while prescribing various diuretics. Furosemide for cystitis is prescribed precisely in this capacity. This approach ensures the regular outflow of large volumes of urine, which leads to a decrease in inflammation and signs of intoxication.
However, Furosemide for cystitis cannot be the only medicine or form the basis of therapy. It must be remembered that bacterial inflammation requires the use of antibiotics or at least drugs based on medicinal herbs antiseptic action, if we are talking about initial stage diseases. In the absence of proper treatment, the disease will progress, and in addition to the discomfort when urinating, with which it all began, symptoms such as:
If symptomatic picture will be replenished with the above symptoms, the patient will be indicated for hospitalization and long-term treatment. Otherwise, the patient’s condition will worsen even more, and the disease will lead to serious complications.
Furosemide for edema
If Furosemide is prescribed for cystitis to stimulate the excretion of urine and increase the volume of circulating fluid, then for edema it is used to remove excess fluid from the body. In this case, the patient is usually advised, on the contrary, to reduce the amount of water consumed.
It is very important to maintain a balance in the process of water-salt metabolism. The fluid consumed and output must be equivalent in volume. Otherwise, excess fluid will accumulate in the body. If it begins to be deposited in tissues and cavities, a person may not notice it at first. Only external swelling that forms on the face, limbs, etc. become noticeable immediately.
Edema occurs due to a number of diseases and dysfunctions. For example, due to allergies, liver diseases, due to the use of certain medications. In any case, excess fluid must be removed from the body. In the absence of contraindications, Furosemide can be used for edema.
In this case, it is usually prescribed in a standard dosage - 1 tablet per day (in the morning) every day, as swelling decreases, once every two or three days, until complete cessation of use.
It is noted that a person who has taken the drug once already notices some reduction in swelling, and after a few days they, in most cases, go away completely.
Of course, in this case it is necessary to take other measures, primarily aimed at eliminating the causes that caused the appearance of swelling. If the disease that provoked the formation of edema is not cured, then this symptom after stopping furosemide, it will return again. Meanwhile, this drug should not be abused. It must be used according to the schedule established by the attending physician and only after a prescription has been made.
You should be aware that uncontrolled use of diuretics, including Furosemide, can lead to very severe consequences. In addition, with the fluid removed from the body, especially in large volumes, many useful elements are washed out, such as magnesium, calcium, potassium, sodium, etc. If the drug is prescribed by a doctor, he gives recommendations for correcting nutrition or prescribes vitamin and mineral complexes.
If for some reason the use of diuretics is impossible, for example, the maximum permissible duration of the course of taking Furosemide has been exceeded, you can use other methods of relieving edema. For example, a light stroking massage, foot baths, and rest help a lot in this case. You can consult with a specialist who can offer additional options eliminating this symptom.
Any changes in the patient’s condition and therapy for swelling should be monitored by the attending physician, since self-medication can lead to impairment water balance in the body, which in itself is very dangerous.
To remove excess fluid from the body, as well as to cleanse it and balance the acid-base level, diuretics are used, which in medicine are called diuretics. They can be of 2 types: synthetic and natural.
Usually prescribed to patients with problems of the heart muscle, liver, kidneys, high blood pressure, if the pathology is accompanied by edema. In addition, patients are prescribed pulmonary edema, brain, intoxication harmful substances excreted unchanged by the kidneys.
A diuretic is a drug widely used in medicine. However, when taking this drug, few people think about what effect Furosemide has on the body and what side effects and consequences may be encountered after completing the intake.
The principle of action of a diuretic
Furosemide – pharmacological agent with a diuretic effect, related to “loop” diuretics. It is able to accelerate the formation of urine and reduce the volume of fluid in the tissues of the body. The medicine is very powerful and starts the process almost instantly, however, its effect does not last long.
20 minutes after administration, the mechanism of action starts, the greatest effect is achieved after 2 hours and lasts 3-6 hours. The drug has a depressing effect on the reabsorption of sodium and chlorine ions, and promotes the excretion of calcium, potassium, and magnesium ions. Furosemide has a strong diuretic effect, natriuretic and chloruretic effects.
When using tablets for heart failure, the load on the heart subsides 20 minutes after taking it. After 60-120 minutes, blood circulation decreases, vascular tone decreases and the amount of fluid in the tissues decreases. It is at this moment that Furosemide reaches the peak of its effect. The leaching of sodium chloride also increases, which helps lower blood pressure.
Side effects
Let's list which adverse reactions from the body may occur, as well as their symptoms:
Furosemide is dangerous medicine, which can lead to serious disruptions in the human body. For this reason, the drug should be taken only as prescribed by a doctor and the dosage should be adjusted as necessary.
The dangers of long-term use of a diuretic for weight loss
Long-term use of Furosemide during weight loss increases the risk of side effects, and the chance of death due to metabolic disorders and cardiac arrest increases significantly. This is due to the fact that a pronounced deficiency of minerals necessary for normal functioning all organs and systems.
For this reason, long-term use of any diuretics is prohibited. Physically, a person loses performance, endurance, the body loses the ability to regulate body temperature, which leads to dehydration, weakness, and disruption of blood circulation.
Why the drug is dangerous: unpleasant consequences
Due to long-term use of the drug, a dose-dependent effect appears in humans. In more detail, an increase in the volume of urine occurs due to the intake different quantities medicine associated with pathology and personal characteristics the patient's body. In addition, over time, the kidneys stop responding to the initial dose, which requires increasing it.
Cases have been recorded when, when diuretics are discontinued, a person experiences psychological changes, i.e. there is a direct dependence on the drug. This is especially true for those who independently practice taking Furosemide for weight loss.
Pseudo-Bartter syndrome may also develop. The pathology is characterized by water and electrolyte disturbances - a decrease in the concentration of potassium, sodium, chlorine in the blood, a violation acid-base balance, signs of dehydration appear, and plasma renin activity increases.
Benefits of using the drug
However positive sides the drug still has. It helps to quickly remove poisons, toxins and excess fluid, thereby relieving swelling. That is, it performs its original functions properly.
IMPORTANT! Taking the drug under the supervision of a doctor in combination with other medications does not cause any harm.
How to recover from Furosemide
After stopping the diuretic, the patient's swelling may worsen. This may happen for one of the following reasons:
- A consequence of a disease treated with Furosemide. In this case, you will need to consult your doctor with subsequent correction of the pathology.
- Symptom of drug addiction.
With the furosemide-dependent effect, everything is a little more complicated. You will need to take mineral supplements medications containing potassium and magnesium, it is better to consume liquid in small quantities. Use as a diuretic herbal teas. It is advisable to drink no later than 4 o’clock in the afternoon, and last appointment eat food until 6 pm. These recommendations will have to be followed for 30 days or more.
In order to prevent hypokalemia, you need to introduce foods with high content potassium - nuts, dried apricots, raisins, beans, peas and other legumes, seaweed, potatoes. At the same time, it is recommended to take potassium supplements.
To compensate for magnesium deficiency, you will need to take chloride or magnesium gluconate. Sodium chloride therapy for low sodium levels in the blood is carried out carefully, since salt retains fluid in the body.
Opinions of patients and doctors
Below are provided real reviews doctors and patients. Let's find out what opinion has formed about the diuretic in medical practice and among those who used the drug for any reason.
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