Panadol - syrup, suppositories and tablets to eliminate the temperature symptoms of colds and flu. Use of children's Panadol for fever and pain

Inflammation is a kind of protective reaction of the body to various pathogens (bacteria, viruses, chemical compounds). At the same time, the body releases special substances into the blood; waste products poison the child’s body. For pain relief, elimination unpleasant symptoms use non-steroidal drug– Panadol Baby syrup.

The drug effectively copes with the baby’s fever and relieves pain that accompanies almost every cold. Children's Panadol is very popular among parents; in most cases, the medication is reviewed positively.

Pharmacological properties

Panadol for children belongs to the group of non-steroidal anti-inflammatory drugs, antiseptics. The active component is paracetamol, the substance is capable of blocking inflammatory mediators that provoke inflammatory process, increased body temperature, and other unpleasant cold symptoms.

A distinctive feature of the drug is the slight anti-inflammatory activity of the component, after all, when a substance enters the blood, it begins to break down under the action of cell membrane enzymes. The drug has a loyal effect on the children's body, in rare cases it causes side effects. According to instructions, maximum concentration Panadol Baby is reached after half an hour, so the medicine acts quickly and significantly alleviates the baby’s condition.

The destruction of the drug elements occurs in the liver, then the active component of the syrup is excreted by the kidneys. If the dosage is observed, the drug does not violate electrolyte balance, water retention does not occur, the functioning of the gastrointestinal tract remains normal.

Composition and release form

Panadol Baby is produced in the form of syrup for oral administration. The bottle contains 100 ml of medicine, a convenient dispenser makes the process of taking the medicine easier. The liquid has a pinkish color, a characteristic viscous consistency and a pleasant strawberry aroma. The manufacturer produces the product in the form of pills, powder, solution for infusion, rectal suppositories. For children, a suspension is most often used. Pleasant taste, ease of use have earned the love of many children and their parents.

The main component of Panadol for children is paracetamol. The substance was first synthesized in the USA back in 1887. It was tested and studied for quite a long period of time, and some scientists doubted its effectiveness. Mass production of paracetamol began only in 1953, and the substance is extremely popular today.

Paracetamol was originally used as a pain reliever for varying degrees of pain. In addition, the substance was actively used to solve problems with the gastrointestinal tract in children.

Note! During the research, it was found that Panadol acts effectively, copes well with headaches, toothaches, fever, and alleviates colds. Do not exceed the dosage due to the high risk of side effects if the recommendations described in the instructions are not followed.

Indications for use

Children's Panadol is used in the following cases:

to lower the baby’s body temperature, reduce the unpleasant symptoms of colds (flu, and others);
relief, including with;
elimination of pain from otitis media, sinusitis, tonsillitis, ;
sometimes used to alleviate the condition of various neuralgic problems (only with the permission of the doctor);
in some cases, they are used once for children 2–3 months after vaccination. The instructions indicate that the drug copes with unpleasant sensations, reduces the risk of side effects after vaccination.

Panadol is approved for use by children from three months up to twelve years old. Before using the medicine, consult your pediatrician, strictly follow his recommendations.

Contraindications

Children's Panadol is prohibited from taking in the following cases:

the presence of hypersensitivity to paracetamol or other components of the drug;
blood diseases;
children up to three months of age (can only be taken with the permission of the pediatrician);
serious liver dysfunction;
kidney pathologies;
It is not recommended to combine it with other drugs containing paracetamol.

Before use, be sure to carefully read the instructions and follow the helpful instructions.

Possible side effects

Exceeding the dosage or individual intolerance to the components of the medication leads to a number of unpleasant consequences.

Malfunction gastrointestinal tract:

loss of appetite;
attacks of nausea;
loss of appetite, lethargic state of the baby;
severe pain in the intestinal or stomach area;
Excessive, constant excess of the dosage leads to necrosis of liver cells, resulting in liver failure.

Nervous system problems:

in some cases it is noted increased activity baby, insomnia, excessive anxiety;
a single dose of a large amount of Panadol leads to dizziness, severe pain in the temples, sometimes – loss of consciousness.

Answer immune system (allergic reactions):

swelling respiratory tract, Quincke's edema;
rash on the body, redness in the area of formations;
the most serious complication is Stephen-Jones syndrome (which is drug-induced tissue necrosis). Sometimes Lyell's syndrome (damage to epidermal tissues) appears. Pathological conditions require immediate medical intervention, emergency resuscitation.

Lesions of the hematopoietic organs:

children are pale skin face, cyanosis of the nasolabial triangle, sometimes pain is felt in the heart area;
thrombocytopenia is noted, which is accompanied by excessive bleeding and poor blood clotting;
long, uncontrolled reception The medication leads to disturbances in the functioning of the bone marrow.

From the endocrine system:

glycemic coma;
lowering blood sugar levels.

Sometimes kidney failure and problems with urination develop.

Instructions for use and dosage

Panadol syrup for children is taken orally, Before use, be sure to stir the suspension in the bottle. Using a measuring syringe, draw up the required amount of product and pour it into the baby’s mouth. After use, rinse the device.

Approximate regimen of use and dosage of Panadol:

2–3 months– individual dosage is prescribed exclusively by the attending physician;
3–6 months– give the baby 4 ml, the maximum permissible daily dose is 16 ml;
from 6 months to 1 year– 5 ml up to four times in a day;
from one to two years– 7 ml, per day up to 28 ml;
from one to two years– 9 ml, allowed to use up to 36 ml per day;
from three years to six years– 10 ml, the maximum allowed to give the baby is 40 ml;
from six to nine years– 14 ml, you can give the baby 56 ml per day;
from nine to twelve years– 20 ml, 80 ml can be taken daily.

Anyway the specific dosage is prescribed by the attending physician, It is not advisable to give the drug to your child yourself.

Interaction with other drugs

Panadol for children It is not recommended to combine it with other anti-inflammatory, antipyretic medicinal products. Even when combined with multivitamins, notify your doctor. The child's body is very sensitive and reacts sharply to taking several medications at the same time.

Dosage form: suspension for oral administration Compound:

Composition (per 5 ml suspension)

Active substance: paracetamol 120 mg.

Excipients: malic acid 2.5 mg, gumxanthan 35.0 mg, maltitol3500.0 mg, sorbitol 70%crystalline 666.5 mg, sorbitol105.0 mg, citric acid 1.0 mg,parahydroxybenzoic ester mixtureacids (methyl-, ethyl-,propyl parahydroxybenzoatessodium) 7.5 mg, strawberry flavorL1005 5 5.0 mg, azorubine dye 0.05 mg, water up to 5.0 ml.

Description:

Pink viscous liquid with a strawberry odor, containing crystals.

Pharmacotherapeutic group:Analgesic non-narcotic drug ATX:

N.02.B.E Anilides

N.02.B.E.01 Paracetamol

Pharmacodynamics:The drug has analgesic and antipyretic properties. Blocks cyclooxygenase in the central nervous system, affecting the centers of pain and thermoregulation. The anti-inflammatory effect is practically absent. It does not affect the condition of the gastrointestinal mucosa and water-salt metabolism, since it does not affect the synthesis of prostaglandins in peripheral tissues. Pharmacokinetics:

Absorption is high - Panadol is quickly and almost completely absorbed from the gastrointestinal tract. Plasma protein binding is about 15%. Peak plasma concentrations are reached after 30-60 minutes.

The distribution of paracetamol in body fluids is relatively even.

Metabolized primarily in the liver with the formation of several metabolites. In newborns in the first two days of life and in children 3-10 years of age, the main metabolite of paracetamol is paracetamol sulfate; in children 12 years of age and older, it is conjugated glucuronide. Part of the drug (approximately 17%) undergoes hydroxylation to form active metabolites that are conjugated with glutathione. With a lack of glutathione, these metabolites of paracetamol can block the enzyme systems of hepatocytes and cause their necrosis.

The half-life when taking a therapeutic dose ranges from 2-3 hours.

When taking therapeutic doses, 90-100% of the dose taken is excreted in the urine within one day. The main amount of the drug is released after conjugation in the liver. No more than 3% of the received dose of paracetamol is excreted unchanged.

Indications:

Used in children from 3 months to 12 years as:

Antipyretic - to reduce elevated body temperature due to colds, flu and childhood infectious diseases(chicken pox, mumps, measles, rubella, scarlet fever, etc.)

Pain reliever for toothache, including teething, headache, ear pain for otitis media and sore throat.

For children 2-3 months of age, a single dose is possible to reduce fever after vaccination. If the temperature does not decrease, consult a doctor.

Contraindications:

Hypersensitivity to paracetamol or any other ingredient of the drug;

- pronounced violations liver or kidney function;

Newborn period

Carefully:Use with caution whenliver dysfunction (incl.Gilbert's syndrome), kidneys,genetic absence of the enzymeglucose-6-phosphate dehydrogenase,severe forms of blood diseases(severe anemia, leukopenia,thrombocytopenia).If there is any oflisted diseases beforethe drug should be takenconsult your doctor. Directions for use and dosage:For oral administration.

Before use contentsthe bottle needs to be goodshake for at least 10 seconds The measuring syringe included inside the package allows you to correctly andrationally dose the drug. The dose of the drug depends on the age and body weight of the child.

Children (from 3 months to 12 years)

The maximum single dose is 15 mg/kg body weight. The maximum daily dose is 60 mg/kg body weight. The frequency of administration is no more than 3-4 times a day. If necessary, you can givechild the recommended dose every 4-6 hours, but not more than 4 doses in 24 hours.

In all other cases before When taking the drug "Children's Panadol" you need to consult a doctor.

Body weight (kg)	Age	Dose
		One-time		Maximum daily
		ml	mg	ml	mg
4,5-6	2-3 months	Only on doctor's orders
6-8	3-6 months	4.0			384
8-10	6-12 months	5.0	120		480
10-13	1 -2 years	7.0	168		672
13-15	2-3 years	9.0	216		864
15-21	3-6 years	10.0	240		960
21-29	6-9 years	14.0	336		1344
29-42	9-12 years	20.0	480		1920

Duration of use without consulting a doctor is 3 days.

If the child's condition does not improve while taking the drug, consult a doctor.

Side effects:At recommended doses, the drug is usually well tolerated. The following side effects were detected spontaneously during post-registration use of the drug.

Side effects are classified by organ system and frequency. The frequency of side effects is defined as follows: very often (greater than or equal to 1/10), often (greater than or equal to1/100 and less than 1/10), uncommon (greater than or equal to 1/1000 and less than 1/100), rare (greater than or equal to 1/10,000 and less than 1/1000) and very rare (greater than or equal to 1/100 000 and less than 1/10,000).

Allergic reactions:

Very rarely - in the form of skin rashes, itching, urticaria, angioedema, Stevens-Johnson syndrome, anaphylaxis;

From the hematopoietic system:

Very rarely - thrombocytopenia, anemia, leukopenia;

From the outside respiratory system:

Very rarely - bronchospasm (in patients with hypersensitivity to acetylsalicylic acid and other non-steroidal anti-inflammatory drugs);

From the hepatobiliary system:

Very rarely - liver dysfunction.

Sometimes nausea, vomiting, and pain in the stomach are possible.

If any of these side effects occur, stop taking the drug and consult your doctor immediately.

Overdose: Symptoms : during the first 24 hours after an overdose, nausea, vomiting, stomach pain, sweating, pale skin, anorexia. After 1-2 days, signs of liver damage are determined (pain in the liver area, increased activity of “liver” enzymes). Possible development of a disorder carbohydrate metabolism And metabolic acidosis. In adult patients, liver damage develops after taking more than 10 g of paracetamol; in children, when taking more than 125 mg/kg of the child’s body weight. If there are factors influencing the toxicity of paracetamol to the liver (see section "Interaction with other medicines", "special instructions") liver damage is possible aftertaking 5 or more grams of paracetamol.

IN severe cases overdose as a result liver failure encephalopathy (impaired brain function), bleeding, hypoglycemia, cerebral edema, and even death may develop. Possible development of acute renal failure with acute tubular necrosis, characteristic features which is pain in the lumbar region, hematuria (admixture of blood or red blood cells in the urine), proteinuria ( increased content protein in the urine), while severe liver damage may be absent. There have been cases of violations heart rate, pancreatitis.

With long-term use exceeding the recommended dose, hepatotoxic and nephrotoxic effects may occur ( renal colic, nonspecific bacteriuria, interstitial nephritis, papillary necrosis).

Treatment : If an overdose is suspected, even in the absence of pronounced first symptoms, it is necessary to stop using the drug and immediately seek medical advice. medical assistance. Within 1 hour after an overdose, it is recommended to lavage the stomach and take enterosorbents (, polyphepan). The level of paracetamol in the blood plasma should be determined, but not earlier than 4 hours after the overdose (earlier results are unreliable). Administration of acetylcysteine within 24 hours of an overdose. The maximum protective effect is provided during the first 8 hours after an overdose; over time, the effectiveness of the antidote drops sharply. If necessary, administer intravenously. In the absence of vomiting, methionine can be used before the patient is admitted to the hospital. The need for additional therapeuticmeasures (further administration of methionine, intravenous administration of acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as on the time elapsed after its administration. Treatment of patients with serious violation liver function tests 24 hours after taking paracetamol should be carried out in conjunction with specialists from a poison control center or a specialized liver disease department. phenylbutazone

, butadione, preparations of St. John's wort and others inducers of microsomal oxidation increase the production of hydroxylated active metabolites, causing the possibility of developing severe liver damage with small overdoses of paracetamol (5 g or more).

Inhibitors of microsomal liver enzymes reduce the risk of hepatotoxicity.

Under the influence of paracetamol, the elimination time of chloramphenicol (chloramphenicol) increases by 5 times, resulting in an increased risk of chloramphenicol (chloramphenicol) poisoning.

When taken regularly over a long period of time, the drug enhances the effect of indirect anticoagulants (and other coumarins), which increases the risk of bleeding. Occasional administration of a single dose of the drug does not have a significant effect on the effect of indirect anticoagulants. and increase andreduces the rate of absorption of paracetamol. The drug may reduce the effectiveness of uricosuric drugs.

Special instructions:

Children under 3 months and children born prematurely"Children's Panadol" can only be given as prescribed by a doctor.

When conducting tests to determine uric acid and blood sugar levels, tell your doctor about using the drug "Children's Panadol".

When taking the drug for more than 7 days, it is recommended peripheral blood control and functional state of the liver. Glutathione deficiency due to disorder eating behavior, cystic fibrosis, HIV infection, starvation, exhaustion causes the possibility of developing severe liver damage with small overdoses paracetamol (5 g or more).

The drug should not be used simultaneously with others paracetamol containing drugs.

"Children's Panadol" contains maltitol and. Patients with rare hereditary fructose intolerance should not take this drug. The drug contains a mixture of parahydroxybenzoic acid esters (sodium methyl, ethyl, and propyl parahydroxybenzoates), which may cause delayed allergic reactions.

"Children's Panadol" does not contain sugar, alcohol and acetylsalicylic acid.

Release form/dosage:Oral suspension, 120 mg / 5 ml. Package: Primary packaging

100, 300 and 1000 ml in dark glass bottles.

Secondary packaging

1 bottle along with a measuring syringe and instructions for use will be placed in a cardboard box.

Packaging for hospitals

10-50 bottles of 1000 ml, along with instructions for use, are placed in a cardboard box.

Storage conditions:

At temperatures not exceeding 30° C. Protect from light. Do not freeze. Keep out of the reach of children.

Best before date: 3 years. Do not use after the expiration date stated on the package. Conditions for dispensing from pharmacies: Over the counter Registration number: P N011292/01 Registration date: 23.04.2010 / 26.04.2016 Expiration date: Instructions

During illness, it may be necessary to take medication before seeing a doctor to relieve symptoms. Panadol syrup is one of the effective available funds, used as antipyretic drug. The medicine is available for both adults and children. You can buy it at a pharmacy without a doctor's prescription.

The suspension is produced in containers made of dark material with a volume of 100, 300 and 1000 ml. The package includes instructions for use and a measuring syringe for accurate dose measurement.

The composition per 5 ml of the drug contains:

120 mg paracetamol;
additional substances to create taste and consistency: malic and citric acid, sorbitol, sodium nipasept, xanthan gum, glucose syrup hydrogenate, azorubine, and to give a pleasant consistency and taste - strawberry flavor and water;
a product called Panadol Extra contains caffeine.

The syrup looks like a viscous liquid and has a pleasant berry smell.

The manufacturer also offers the product in the form of tablets, soluble powder and suppositories. As a rule, suppositories are effective as a symptomatic medicine for children. Only a doctor can prescribe Panadol in the form of suppositories; it is not recommended to personally decide on the use of this type of medication.

Pharmacological action and indications for use

The reason for taking the medicine may be:

Migraine and headache.
Painful sensations in the teeth.
Painful spasms in the lower back and muscles.
Neuralgia.
Pain during menstruation.
Reducing temperature during colds, infectious and viral diseases.

Paracetamol is a long-known effective remedy against pain of various types and high temperature. In small dosages, the substance can be given to children; for adults, the volume should be increased in accordance with body weight.

Panadol: instructions for use for adults and children

Children's syrup Panadol Baby can be used in the treatment of children from 3 months to 12 years inclusive. Before taking the product, shake the contents of the bottle thoroughly.

Then measure the required dose using a special spoon or syringe, which are usually included in the package, and take the suspension in accordance with the instructions:

Children: 15-60 mg per 1 kg of weight, depending on age. Up to six months maximum daily dosage for children is 350 mg, up to one year - 500 mg, at the age of 1-3 years - up to 750 mg, up to 6 years - no more than 1000 mg. With a weight of less than 30 kg, from 6 to 9 years of age, the daily maximum is 1500 mg, up to 12 years - a maximum of 2000 mg. The number of doses is 3-4 times during the day, at regular intervals. It is strictly not recommended to do more than 4 techniques.
Adults weighing more than 60 kg and adolescents weighing more than 40 kg are recommended to take the medicine in a volume of 500 mg at a time, with a maximum dose of no more than 1000 mg. Duration of treatment is from 5 to 7 days.

Detailed instructions describing how to take the medicine are included in the package. Before taking, or better yet before purchasing, a medicine, you must study it carefully.

Special instructions for taking syrup

Experts allow syrup to be given once to children 2-3 months old to reduce body temperature after administration of the vaccine. If the method did not work positive effect, you need to urgently consult a doctor.

Important! Newborns who were born ahead of schedule, and only a doctor can prescribe medicine for children under 3 months of age! Self-medication is dangerous and unacceptable!

If the drug is taken without a pediatrician’s prescription (at the age permitted by the instructions) as an antipyretic, the period of administration is up to 3 days; as a pain reliever - up to 5 days.

If the patient has pathologies of the liver, kidneys, a disease called "Gilbert's syndrome", as well as in old age, the recommended daily dose substances must be reduced, and the time interval between doses must be increased.

If you have alcoholic hepatosis, taking the medication increases the likelihood of developing liver damage.

Note! If planned laboratory test to determine glucose and uric acid, you need to stop taking the drug a couple of days in advance - the substance distorts the real indicator.

Drug interactions with other drugs

At complex treatment It is important to consider how using certain substances together can affect the body.

There is a possibility of a hepatotoxic reaction if the drug is used simultaneously with the following drugs:

barbiturates;
diphenin;
rifampicin;
butadione;
various anticonvulsants.

If the syrup is combined in one therapy with chloramphenicol, there is a high probability that the latter will increase its toxicity.

At long-term use paracetamol, an anticoagulant effect of coumarin derivatives is observed. This reaction may result in bleeding.

Contraindications, side effects and overdose

The following should be noted as contraindications:

special sensitivity to substances contained in the medicine;
failure of the liver and kidneys;
newborn 1-2 months old.

Side effects can occur if the drug is taken incorrectly, despite contraindications.

In this case, you can expect the following consequences:

allergic rash;
nausea, sometimes leading to vomiting;
painful stomach cramps;
in some cases there is a possibility of anemia, leukopenia and thrombocytopenia.

Important! If the above side effects occur, immediately call a doctor at home.

Analogues of antipyretic drugs for children and adults

The following options can be considered as analogues for the main active ingredient:

Akamol Teva. Available in tablets, syrup, and candles for children. The product in the form of suppositories is prescribed by a pediatrician.
Daleron. In addition to the main substance, it has additional components to create a pleasant texture and fruity taste. Contains fructose, which may be a contraindication for use.
Lupocet. Available in several forms: powder, syrup, capsules, solutions. Can be used from 1 month. Typically, painkillers antipyretic syrup washed down with plenty of liquid. You need to take it a couple of hours after eating, as food blocks the absorption of the product. At the same time, the medicine should not be taken on an empty stomach.
Meksalen. Contains paracetamol. Available in tablet form. Used as an antipyretic and analgesic.
Paracetamol. Available in in different forms, including flavored syrup for children. Allowed for use from 3 months. For young children, a single dose can be added to a bottle of water.
Perfalgan. The active ingredient is paracetamol. It comes in the form of syrup, powder for dilution in liquid, capsules, suppositories. Acceptable age: from 1 month.
Efferalgan. The basis is the substance paracetamol. Allowed for children from the age of 1 month as an antipyretic and analgesic. Available without a prescription.

Each analogue has some contraindications, possible side effects if taken incorrectly, and treatment features in general. Despite the possibility of purchasing the medicine without a prescription, it is recommended to discuss treatment with your doctor.

(the main active substance included in Panadol) can be found in pharmacies in various dosage forms Oh. These are capsules, suspension, effervescent powder for the preparation of oral solution for children, oral solution for children, solution for infusion, rectal suppositories, syrup, rectal suppositories for children, oral suspension, tablets. Each of the listed forms is indicated at a certain age and situation, taking into account the patient’s condition and individual sensitivity.

Since the main component of Panadol is paracetamol, you should start with its description in order to find out the essence of the drug, its functions, indications, contraindications for certain age categories. Paracetamol was synthesized in the USA at Johns Hopkins University back in 1877. For a long time Studies have been conducted with controversial results and preference for other drugs. As a result, mass production and sale of Paracetamol began only in 1953.

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Paracetamol was positioned on the pharmaceutical market primarily as a painkiller for pain medium degree. Paracetamol was especially popular as a remedy for headaches and migraines. In addition, Paracetamol was recommended as more safe medicine for children with gastrointestinal diseases. Paracetamol under trade name Panadol began to be produced in 1956, and its sale was carried out only by prescription.

In the USA, studies were conducted to identify the effects of the substance paracetamol on the human body. This was due to the fact that Americans often received poisoning from these drugs, considering Panadol to be a medicine that had minimal effects on the digestive organs. What positive and negative effects were identified in patients using this drug?

Panadol is well tolerated and acts quite effectively, lowering body temperature and relieving headache, dental, muscle pain. Considering Panadol a “harmless” drug, many take it for any reason and in large doses. As a result of exceeding the dose, the observed patients in the study group primarily experienced side effects such as allergies and liver dysfunction, expressed in increased liver enzymes. Less serious side effects An overdose resulted in dizziness, abdominal pain, and nausea. The study of the drug continues to this day, discovering new properties, indications and contraindications for taking the drug. What can I say in defense of the drug?

Panadol is a good antipyretic that does not cause serious negative impact on the body of an adult and a child when taken infrequently and correctly (regarding dosage). Each dosage form of the drug has its own characteristics, and therefore requires a detailed study of the composition, properties, indications, etc.

Panadol Extra: description and mechanism of action

Panadol Extra is produced in two forms: coated tablets and a soluble form in effervescent tablets. In both versions active ingredients Contains paracetamol and caffeine. Panadol Extra refers to analgesics and antipyretics, drugs that can relieve pain and lower body temperature.

Panadol is an antipyretic and analgesic. According to the instructions, the tablets are prescribed for headaches and migraines, influenza and other viral infections, sore throat, tonsillitis and other inflammations of the respiratory system, sciatica and lumbago, lesions of the oral mucosa, rheumatism, myalgia, neuralgia and neuritis, and other pain syndromes of an unspecified nature. These are the areas of application of the drug.

Paracetamol and caffeine act together and enhance each other's properties. Paracetamol reduces the rate of prostaglandin production, increases heat transfer and reduces the degree of excitability of the thermal center. The human thermal center is located in the brain and regulates body temperature. If he is in excited state under the influence of life activity viral infections, body temperature rises, heat production and loss change. As already noted, paracetamol can reduce the excitability of the TC; this is a temporary measure to reduce high fever, since paracetamol does not eliminate the causes of the disease...

...For a long time it was believed that taking antipyretic drugs inhibits the body’s defenses, which, by increasing temperature regime are fighting the infection. Recent studies have revealed that this fact is erroneous and the body continues the antiviral fight, but without such conditions as headache, heaviness, weakness, etc. As for caffeine, it increases the level of paracetamol in brain cells, enhancing its effect on the thermal center. In addition, caffeine increases the permeability of histohematological barriers, which are designed to perform protective function by limiting the transition of foreign bodies from blood to tissue and vice versa.

Regarding the metabolism of these substances, they are broken down in the liver and excreted by the kidneys. In general, both paracetamol and caffeine are perfectly absorbed by the gastrointestinal tract (without irritating it), and are equally distributed throughout the tissues and cells of the brain.

How to take Panadol?

Before deciding to use Panadol, you should study contraindications and precautions to eliminate the possibility of side effects. The tablets should not be taken if there is significant liver or kidney dysfunction, epilepsy, high blood pressure, glaucoma, in childhood up to 12 years old. The drug may give unexpected results when alcohol addiction and viral hepatitis.

Pregnant women should take Panadol Extra with caution, although there is no evidence negative influence The drug has not been established for fetal development. It is known for certain that paracetamol is able to penetrate the placenta into the baby’s body. There is no information about teratogenic effects. As for the use of the drug during breastfeeding, the situation is similar. Paracetamol can pass into the child's body through mother's milk. Its concentration, of course, is small, but the child can react to it, mainly with pain in the gastrointestinal tract. In reviews, Panadol is often mentioned by pregnant and nursing mothers as the main savior against headaches and fever. Here it is important to reduce the dosage and increase the interval between doses. Then risks can be reduced or eliminated altogether. The drug is prohibited during pregnancy and in all other cases if there is an individual intolerance to the components of the drug.

So how to take Panadol? At high temperature as an antipyretic, you should take 1-2 tablets no more often than every 4 hours. If the temperature persists for more than three days, it is advisable to stop taking the drug and consult a doctor. Maximum dose at one time - 2 tablets, and per day - no more than 8 tablets. The dosage of Panadol during pregnancy is reduced to 0.5 tablets. To reduce pain, the dosage remains the same, but the duration of administration can be increased to 5 days.

Panadol Extra tablets: overdose and special instructions

When using Panadol, you need to monitor the intake of other paracetamol- and caffeine-containing drugs and foods. So it’s simply better not to drink too much strong tea and coffee, and avoid alcoholic drinks. When taking both simultaneously, tachycardia, increased excitability, liver intoxication, etc. may occur. For people prone to allergies, the risk of intolerance to the drug increases.

If the dosage of Panadol is not observed, an overdose is possible, manifested by nausea and vomiting, pain in the gastrointestinal tract, and liver damage.

Soluble and insoluble form of the drug: what is the difference?

The difference between these dosage forms lies in the special production method. But the main thing is that effervescent tablets act faster due to instant release active ingredients and do not irritate the gastric mucosa. In addition, soluble Panadol is more pleasant to drink for both children and adults. The tablet must be dissolved in half a glass of water and drunk.

Of the minuses effervescent tablets there is an increased sugar content and an effect on tooth enamel citric acid, which is included in all soluble dosage forms.

Panadol Baby - detailed description

Panadol Baby is produced in the form of syrup and suspension and can be used to treat children from 3 months of age. The drug contains paracetamol and the following excipients: xanthan gum, malic acid, liquid maltitol, azorubine, strawberry flavor, sodium nipasept, sorbitol 70% crystallizing, sorbitol, purified water and anhydrous citric acid. It is important that the syrup and suspension do not contain alcohol.

Indications for taking Panadol for children are high fever as a result of childhood infectious diseases, ARVI and influenza, to relieve moderate pain syndromes. The children's form of the drug is indicated as a pain reliever during teething and after vaccination. This drug can be used to reduce a child’s body temperature in case of illness. chicken pox, whooping cough, mumps, etc.

How quickly does Panadol Baby work?

Immediately after taking the drug, it is absorbed into the plasma from the gastrointestinal tract without irritating it. The effect of taking Panadol occurs within 15 to 60 minutes. Body temperature drops significantly and pain goes away. Panadol Baby, according to the instructions, is not an anti-inflammatory drug, since the paracetamol contained in it is inactivated in the cells of the mucous membranes. Children's syrup and suspension are excreted from the body in 1-4 hours in the urine, breaking down in the liver.

How to take Panadol Baby correctly to alleviate childhood diseases?

Panadol syrup and suspension differ from the tablet form in their speed of action and ease of use. Small children do not know how to swallow tablets, and if they are crushed first, usually some of the drug remains on the spoon or in the baby bottle. Thus, it is difficult to determine the correct dose of the medicine. According to the instructions, it should be taken depending on the child’s body weight and age. The annotation says that the recommended age of the child is 3 months. But often the drug is prescribed in more early age in certain situations. The dose of the drug will be indicated by the doctor.

According to the instructions for Panadol Baby, children from 3 to 6 months are usually prescribed 4 ml every 4 hours. That is, 3-4 times a day if necessary. Paracetamol-containing drugs should never be given to a child more than five times a day. Children from six months to one year are given 5 ml, children from one to two years - 7 ml, from 2 to 3 years - 9 ml, from 3 to 6 years - 10 ml, from 6 to 9 years - 14 ml, up to 12 years 20 ml. The interval between doses is always at least 4 hours. The dosage of children's Panadol must be strictly observed to avoid side effects.

If the child has not yet reached 3 one month old, and due to infection or the post-vaccination period, it is necessary to take an antipyretic drug, the doctor may prescribe Panadol Baby 2.5 ml 1-2 times a day after 4 hours. Although the doctor may change the dosage of the children's version of the drug.

Contraindications

Up to two months of age baby syrup or suspension are not approved for use. They are also contraindicated for premature babies under 3 months. Panadol syrup is not prescribed for changes in the functioning of the liver and kidneys, for blood diseases (anemia and leukopenia), for elevated level bilirubin. If there are signs of individual intolerance to the drug, its use should be avoided. As for the Panadol suspension, in addition to what has already been said, it should be mentioned that it contains fructose, to which young children are also often allergic.

Children's Panadol can be used during pregnancy!

As indicated in the instructions for children's Panadol Baby, it can be used by pregnant women at high temperatures. During pregnancy, the drug has a rapid effect, but is less toxic than tablets for adults. After all, it is designed for a fragile child’s body. Children's Panadol or Nurofen is recommended for pregnant women under medical supervision. Which one is better?

Nurofen, unlike Panadol, also has a pronounced anti-inflammatory effect, therefore it has a threefold effect on the body: antipyretic, analgesic and anti-inflammatory. If the question is Nurofen or Panadol, then it is probably better to use the second throughout pregnancy, and in the first and second trimesters you can take Nurofen. Most the best option– prevention of morbidity, then the issue of taking certain medications will not be so pressing.

If your mother is sick and the high temperature seriously affects your well-being, you can take the syrup version (the dosage is in the description). Since its elimination from the body occurs after about 3 hours, after this time you can continue to breastfeed the baby. You should not get carried away with the drug, especially if the child is not yet 3 months old. Support normal condition follows other more harmless means, since Panadol is not recommended during breastfeeding, even in a child dosage.

Side effects and overdose

In most cases, Panadol is well tolerated by the child’s body, fulfilling its main function as an antipyretic. In some cases, an allergic reaction is possible, manifested by skin rash, itching, etc. As stated in the instructions for children's syrup, there are cases of a response from the gastrointestinal tract: nausea, vomiting, abdominal pain, etc. If a child increased sensitivity to the drug, other, more serious consequences, up to anemia, reduced level blood sugar, bronchospasm, etc.

If the syrup dosage is not observed, symptoms of overdose may occur. These are impaired renal and liver function, problems in the area of hematopoiesis, drowsiness, pallor, loss of appetite, necrosis, nephritis, arrhythmia. If an overdose occurs, patients are usually hospitalized, the stomach is washed, and they are prescribed drug therapy. This is why it is so important to follow the instructions for Panadol syrup and suspension.

Panadol candles for children and description

In addition to active paracetamol, the suppositories contain neutral solid fats. This drug is especially indicated for children with a tendency to vomit and refuse to take tablets and syrups. Panadol suppositories are prescribed for children from six months to 2.5 years. The instructions highlight following cases for taking medication: influenza, ARVI, post-vaccination fever, chickenpox, measles, whooping cough, scarlet fever, painful eruption teeth, sore throat, otitis media, etc.

To insert the suppository correctly, you need to lay the child on his side, slightly bend one leg and index finger insert the suppository. It is better to do this after a bowel movement. You should not forget about hand hygiene before the procedure.

The dosage of Panadol in suppositories depends on body weight and age. One suppository contains 125 mg of active and excipients. A dose of 60 mg per 1 kg of weight should not be used per day. The average dose for a single use is 10-15 mg per 1 kg of child weight up to 4 times a day every 4-6 hours. So, if the child weighs 8-13 kg, one suppository is prescribed 3-4 times a day. The course of use of the drug is 3-5 days.

As for contraindications, side effects, overdose and precautions, they are all typical for all forms of Panadol. The peculiarities of using children's candles lie only in the principle of introduction and age restrictions. If there is inflammation or bleeding in the rectum, taking the drug is prohibited.

Suppositories, tablets or syrup, which is more effective and safer?

Mothers often ask their pediatrician which is better: suppositories, syrup or tablets? Each form has its own pros and cons. Read more about Panadol rectal antipyretic suppositories for children. Candles act faster and longer, as a rule, their effect lasts up to 8 hours. There is no need to force a child to drink a syrup or pill that is unpleasant for him. In addition, their effect does not last more than 3-4 hours. Using candles, you can avoid irritation of the gastrointestinal tract and allergic reactions of the body. But there is one thing... They can irritate the mucous membranes. Therefore, as a candle, it is better to lightly immerse it in Vaseline oil. As stated in the instructions, you should not use suppositories frequently in order to reduce the level of irritation in the rectum. In addition, the content active substance in suppositories is usually higher than in other forms of the drug. Reviews of children's Panadol recommend the following regimen: take antipyretic syrup or tablet in the morning and afternoon, and use children's suppositories in the evening.

A child has a high fever, or what remains outside the instructions for Panadol

High body temperature in children and adults is a sign of the body’s fight against infections that have entered it. If an adult can withstand a temperature of 40-41 degrees, then for a child this fact can become dangerous. Firstly, the risk of seizures increases, and secondly, overheating of the body is possible, which negatively affects not only general health, but also affects internal organs. Initially, to reduce a high temperature, you should try methods such as wiping, lowering the room temperature, light clothing and plenty of warm drinks...

...If these non-drug methods do not produce results even by 1 degree, it is necessary to use medications. Ibufen, Nurofen or Panadol for children help well with this. If the temperature has persisted for a long time, you can start by using rectal suppositories, this measure will allow for some time children's body relax. Whatever drug is chosen as an antipyretic, first of all you need to carefully study the instructions and exclude your own child from the list of contraindications. Only then can you start taking the drug.

Reviews at a Glance

Most of reviews of Panadol characterize it as an effective antipyretic and analgesic drug. The drug very rarely causes allergies, which is important in case of illness small child. It works quickly and for a long time, but not for everyone. Some parents do not see much effect from taking the drug. And this can happen. Each body reacts individually to synthetic drugs. Perhaps, at too high a temperature, this drug is not the most effective remedy, but one of the safest. Largest quantity votes were cast in favor of Panadol rectal suppositories...

...Their main advantage is their long-term effectiveness as an antipyretic. In any case, Panadol for children will reduce the temperature by at least one - and this will already alleviate the baby’s condition. Parents need to be very attentive to their sick child. There is no need to categorically prohibit him from doing anything or, conversely, demand him. Let him be calm, then recovery will come faster.

Prices

Like most drugs, the price of Panadol depends on the form of release. So the cheapest form is insoluble tablets (21-26 rubles). The price for candles is 70-89 rubles, the price for syrup is 98-112 rubles, for the suspension – about 80 rubles. Price soluble Panadol about 52-70 rub.

Medicines with antipyretic effects are certainly present in the medicine cabinet of families with small children, because elevated body temperature can be called one of the most common symptoms childhood diseases

Drugs are often used to combat fever in children. based on paracetamol, because they are called one of the safest in childhood. A representative of such medications is Children's Panadol. When is it prescribed to children, in what dosages is it prescribed, is it used in infants, and what analogues are replaced if necessary?

Release form

Children's Panadol, which is also called Panadol Baby, comes in two forms:

Suspension. This Panadol is a sweet-tasting syrup-like liquid (due to its viscous consistency, this medicine is often called syrup) with a strawberry aroma and a pink tint. The solution is bottled in glass bottles and sold in two volumes - 100 ml and 300 ml. The bottle comes with a plastic syringe that helps you accurately measure milliliters of suspension.
Rectal suppositories. They are sold in a box of 5 to 20 pieces, packed in strips of 5-10 suppositories. These candles have a uniform structure, cone shape and white color. Normally, a candle released from packaging should not have physical defects or any impurities.

Compound

The main ingredient in both forms of Panadol Baby is paracetamol. In the suspension it is contained in a dose of 120 mg / 5 ml, and in one suppository - in the amount of 125 mg or 250 mg.

The only one additional component suppositories are solid fat, and liquid Panadol contains many excipients, including maltitol, flavoring, sorbitol, malic acid, azorubine and other compounds. However There is no sugar or alcohol in the suspension.

Operating principle

Paracetamol in Children's Panadol can affect cyclooxygenase. This enzyme, which is found in the cells of the central nervous system, is responsible for the formation of prostaglandins. Its inhibition interferes with the synthesis of such substances, as a result of which the medicine affects the centers of pain and thermoregulation. This leads to a gradual decrease in temperature and disappearance of pain.

Compared to others non-steroidal drugs with the same effects, Panadol has almost no anti-inflammatory effect. This medication does not affect the synthesis of prostaglandins, which occurs in peripheral tissues. This determines absence harmful effects medications for the digestive tract.

Paracetamol from the suspension is absorbed faster than from suppositories. The effect of the liquid drug taken orally begins in approximately 15-20 minutes, and after administration of the suppository, the effect develops within 1.5-2 hours. The duration of action of both forms is about 4 hours.

Metabolic transformations of paracetamol take place in the liver, and approximately 90% of this substance leaves the body within 24 hours in the urine.

Indications

The most common reason for using Children's Panadol is elevated temperature bodies. The medicine is given:

with the flu;
with scarlet fever;
with ARVI;
for measles;
with chicken pox;
with intestinal infection;
for mumps and other childhood infections;
when a temperature reaction to the vaccine appears.

Since Panadol is still able to relieve pain, the suspension and suppositories are also used for pain syndrome. The drug is in demand for teething, pain in the ears caused by otitis media, pain due to a bruise, pain in the throat due to a sore throat, and so on.

From what age is it used?

It is usually not prescribed to babies under 3 months of age, but the drug can be given to an infant for 1-3 months to reduce the temperature caused by vaccination. However, such a dose should be one-time and only under the supervision of a doctor. If after one dose the medication does not bring down the temperature, you should not give the syrup again.

The suspension is strictly contraindicated for babies in the first month of life.. The question of using the suspension in children older than 3 months who were born prematurely is decided by the doctor.

Adolescents over 12 years of age are also not prescribed the liquid form, since Panadol tablets are 500 mg per adolescence convenient.

Panadol suppositories are not used until six months of age. In this case, suppositories containing 125 mg of the active ingredient are prescribed to children from 6 months to 2 and a half years, and a drug with a higher dose of paracetamol (250 mg per suppository) is used in patients from 3 to 6 years.

There are also weight restrictions for the use of suppositories - a drug with 125 mg is prescribed for a body weight of 8 to 12.5 mg, and suppositories of 250 mg are given to children who weigh from 13 to 20 kg.

Panadol suppositories are not prescribed to patients over 6 years of age and weighing more than 20 kg.

Contraindications

Panadol Baby should not be taken by children:

with intolerance to paracetamol or another component of the drug;
with impaired kidney function;
with a genetically determined absence of glucose 6-phosphate dehydrogenase in the body;
with severe liver diseases;
with anemia and other blood diseases.

The suspension is also contraindicated in case of fructose intolerance, and suppositories are not used in case of inflammation of the rectum or bleeding from this part of the intestine.

Adults when carrying a child or breastfeeding take Panadol not prohibited.

Side effects

Manufacturers warn about the following possible side effects:

When treating Panadol Baby, allergic reactions may occur. In some children they manifest themselves as rashes, in others - itching or redness of the skin, but in rare cases, angioedema, urticaria or anaphylactic shock may develop.
The use of the drug may affect the number of blood cells. A decrease in their number sometimes occurs with prolonged use of Panadol.
If your child is hypersensitive to medications NSAID groups, then taking Panadol can cause bronchospasm.
Very rarely, the medication disrupts liver function or causes negative symptoms from the gastrointestinal tract.

Instructions for use

The drug is used in strict accordance with the instructions in the instructions:

A single dose of Panadol in suppositories is 1 suppository, and the method of administration of such a medicine is rectal.
The suppositories are inserted in a lying position (it is recommended that the child is on the left side with one leg pulled up to the stomach), gently pushing them into the anus with the index finger.
Before using suppositories, you should wait for natural bowel movements or do an enema so that the drug does not leave the intestine immediately after administration.
To dispense the suspension, it is recommended to use a measuring syringe, which is sold along with the bottle. Before drawing the solution with a syringe, you need to vigorously shake the bottle so that all the ingredients are well mixed and distributed evenly.
The dosage of liquid Panadol is determined based on weight and age. For each individual child, you can see it in the table, which is on the box and inside the paper instructions included with the bottle. There are also marked single doses drug, and daily allowance.

In order not to be mistaken with the maximum allowed amount of syrup, it should be calculated based on body weight. In childhood, do not give more than 15 mg of paracetamol per 1 kilogram, and a child can receive a maximum of 60 mg/kg per day.
The frequency of use of both the suspension and suppositories is 3-4 times a day. The drug is given to swallow or injected into the rectum at intervals of 4-6 hours, but Panadol should not be used more than four times a day.
The duration of taking Panadol Baby depends on the reason for its prescription and is adjusted by the doctor. If a child has pain or fever, and it is not possible to show the baby to a doctor, it is allowed to use the medication without consultation for no longer than three days.
If the medicine is prescribed by a doctor for a period of more than 7 days, the risk of side effects must be monitored. In particular, with such long-term use, the child needs to have blood tests and check functional state liver.